Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice

Journal of Diabetes Research

Volumn 2016, Issue , 2016, Pages

  Xie, Yong ^a   Zhang, Yi ^b   Guo, Zebin ^b   Zeng, Hongliang ^b   Zheng, Baodong ^b  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALOID DERIVATIVE; ASPARTATE AMINOTRANSFERASE; CHOLINE BITARTRATE; FATTY ACID; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; ISOLIENSININE; LIENSININE; METHIONINE; NEFERINE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ALKALOID; GLUCOSE BLOOD LEVEL; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; PHOSPHOPROTEIN; PLANT EXTRACT;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; INFLAMMATION; INSULIN RESISTANCE; LOTUS; LOTUS PLUMULE; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; RAT; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; GLUCOSE BLOOD LEVEL; IMMUNOLOGY; LIPID DIET; METABOLISM; NELUMBO; PLANT SEED; WISTAR RAT;

ALKALOIDS; ANIMALS; BLOOD GLUCOSE; DIET, HIGH-FAT; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; NELUMBO; NON-ALCOHOLIC FATTY LIVER DISEASE; PHOSPHOPROTEINS; PLANT EXTRACTS; RATS; RATS, WISTAR; SEEDS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84991633883     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/3965864     Document Type: Article

References (33)

1. J. A. López-Velázquez, K. V. Silva-Vidal, G. Ponciano-Rodríguez et al., "The prevalence of nonalcoholic fatty liver disease in the Americas, " Annals of Hepatology, vol. 13, no. 2, pp. 166-178, 2014.
2. B. P. Mulhall, J. P. Ong, and Z. M. Younossi, "Non-alcoholic fatty liver disease: An overview, " Journal of Gastroenterology and Hepatology, vol. 17, no. 11, pp. 1136-1143, 2002.
3. M. Charlton, "Nonalcoholic fatty liver disease: A review of current understanding and future impact, " Clinical Gastroenterology and Hepatology, vol. 2, no. 12, pp. 1048-1058, 2004.
4. S. A. Polyzos, J. Kountouras, and C. Zavos, "Nonalcoholic fatty liver disease: The pathogenetic roles of insulin resistance and adipocytokines, " Current Molecular Medicine, vol. 9, no. 3, pp. 299-314, 2009.
5. S. A. Zaitone, B. M. Barakat, S. E. Bilasy, M. S. Fawzy, E. Z. Abdelaziz, and N. E. Farag, "Protective effect of boswellic acids versus pioglitazone in a ratmodel of diet-induced non-alcoholic fatty liver disease: influence on insulin resistance and energy expenditure, "Naunyn-Schmiedeberg'sArchives of Pharmacology, vol. 388, no. 6, pp. 587-600, 2015.
6. K. L. Kopec and D. Burns, "Nonalcoholic fatty liver disease: A review of the spectrum of disease, diagnosis, and therapy, " Nutrition in Clinical Practice, vol. 26, no. 5, pp. 565-576, 2011.
7. B. W. SmithandL. A. Adams, "Non-alcoholic fatty liver disease, " Critical Reviews in Clinical Laboratory Sciences, vol. 48, no. 3, pp. 97-113, 2011.
8. C. Masterjohn and R. S. Bruno, "Therapeutic potential of green tea in nonalcoholic fatty liver disease, " Nutrition Reviews, vol. 70, no. 1, pp. 41-56, 2012.
9. J. Xiao, Y. P. Ching, E. C. Liong, A. A. Nanji, M. L. Fung, and G. L. Tipoe, "Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model, " European Journal of Nutrition, vol. 52, no. 1, pp. 179-191, 2013.
10. P. Xin, H. Han, D. Gao et al., "Alleviative effects of resveratrol on nonalcoholic fatty liver disease are associatedwith up regulation of hepatic low density lipoprotein receptor and scavenger receptor class B type I gene expressions in rats, " Food and Chemical Toxicology, vol. 52, pp. 12-18, 2013.
11. G. M. Trovato, G. F. Martines, F. M. Trovato, and D. Catalano, "Regular coffee: A magic bullet or a naked gun? Regular coffee but not espresso drinking is protective against fibrosis in NAFLD, " Journal of Hepatology, vol. 58, no. 6, pp. 1264-1265, 2013.
12. B. Huang, X. Ban, J. He, J. Tong, J. Tian, and Y. Wang, "Hepatoprotective and antioxidant activity of ethanolic extracts of edible lotus (Nelumbo nucifera Gaertn.) leaves, " Food Chemistry, vol. 120, no. 3, pp. 873-878, 2010.
13. Y. Xie, Y. Zhang, L.-T. Zhang, S.-X. Zeng, Z.-B. Guo, and B.-D. Zheng, "Protective effects of alkaloid compounds fromNelumbinis Plumula on tert-butyl hydroperoxide-induced oxidative stress, "Molecules, vol. 18, no. 9, pp. 10285-10300, 2013.
14. W. Liu, H.-J. Wang, N. Si, and B.-L. Bian, "Study on preparation technology of plumula nelumbinis alkaloid dripping pill and determination of content by HPLC, " Journal of ChineseMaterial Medicine, vol. 32, no. 7, pp. 581-584, 2007.
15. D. R. Matthews, J. P. Hosker, A. S. Rudenski, B. A. Naylor, D. F. Treacher, and R. C. Turner, "Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man, " Diabetologia, vol. 28, no. 7, pp. 412-419, 1985.
16. Y. Li, L. Liu, B. Wang et al., "Impairment of reproductive function in a male rat model of non-alcoholic fatty liver disease and beneficial effect of N-3 fatty acid supplementation, " Toxicology Letters, vol. 222, no. 2, pp. 224-232, 2013.
17. S. Deivanayagam, B. S. Mohammed, B. E. Vitola et al., "Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents, " The American Journal of Clinical Nutrition, vol. 88, no. 2, pp. 257-262, 2008.
18. L. J. Goodyear, F. Giorgino, L. A. Sherman, J. Carey, R. J. Smith, and G. L. Dohm, "Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects, " The Journal of Clinical Investigation, vol. 95, no. 5, pp. 2195-2204, 1995.
19. S. A. Zaitone and S. Essawy, "Addition of a low dose of rimonabant toorlist at therapy decreases weight gain and reduces adiposity in dietary obese rats, " Clinical&Experimental Pharmacollogy & Physiology, vol. 39, no. 6, pp. 551-5594, 2012.
20. F. R. Jornayvaz and G. I. Shulman, "Diacylglycerol activation of protein kinase C and hepatic insulin resistance, " Cell Metabolism, vol. 15, no. 5, pp. 574-584, 2012.
21. G. Marchesini, E. Bugianesi, and G. Forlani, "Nonalcoholic fatty liver diseases tea to hepatitis and metabolic syndrome, " Hepatology, vol. 37, no. 4, pp. 917-923, 2003.
22. E. Bugianesi, A. J. McCullough, and G. Marchesini, "Insulin resistance: A metabolic pathway to chronic liver disease, " Hepatology, vol. 42, no. 5, pp. 987-1000, 2005.
23. K. Cusi, "Role of insulin resistance and lipotoxicity in nonalcoholic steatohepatitis, " Clinics in Liver Disease, vol. 13, no. 4, pp. 545-563, 2009.
24. P. Staehr, O. Hother-Nielsen, B. R. Landau, V. Chandramouli, J. J. Holst, and H. Beck-Nielsen, "Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis, " Diabetes, vol. 52, no. 2, pp. 260-267, 2003.
25. A. G. Shah, A. Lydecker, K. Murray, B. N. Tetri, M. J. Contos, and A. J. Sanyal, "Comparison of noninvasive markers of fibrosis inpatientswithnonalcoholic fatty liver disease, " Clinical Gastroenterology&Hepatology, vol. 7, no. 10, pp. 1104-1112, 2009.
26. A. Schäffler, J. Schölmerich, and C. Büchler, "Mechanisms of disease: Adipocytokines and visceral adipose tissue-emerging role in nonalcoholic fatty liver disease, " Nature Clinical Practice Gastroenterology and Hepatology, vol. 2, no. 6, pp. 273-280, 2005.
27. G. S. Hotamisligil, P. Peraldi, A. Budavari, R. Ellis, M. F. White, and B. M. Spiegelman, "IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity inTNF-α-and obesity-induced insulin resistance, " Science, vol. 271, no. 5249, pp. 665-668, 1996.
28. Y. Miyazaki, R. Pipek, L. J. Mandarino, and R. A. DeFronzo, "Tumor necrosis factor α and insulin resistance in obese type 2 diabetic patients, " International Journal of Obesity, vol. 27, no. 1, pp. 88-94, 2003.
29. S. Joshi-Barve, S. S. Barve, K. Amancherla et al., "Palmitic acid induces production of proinflammatory cytokine interleukin-8 fromhepatocytes, " Hepatology, vol. 46, no. 3, pp. 823-830, 2007.
30. S. Schenk, M. Saberi, and J. M. Olefsky, "Insulin sensitivity: modulation by nutrients and inflammation, " Journal of Clinical Investigation, vol. 118, no. 9, pp. 2992-3002, 2008.
31. C. R. Bruce and D. J. Dyck, "Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor necrosis factor-β, " American Journal of Physiology-Endocrinology & Metabolism, vol. 287, no. 4, pp. E616-E621, 2004.
32. L. A. Videla, G. Tapia, R. Rodrigo et al., "Liver NF-KB and AP-1DNA binding in obese patients, " Obesity, vol. 17, no. 5, pp. 973-979, 2009.
33. G. Tuncman, J. Hirosumi, G. Solinas et al., "Functional in vivo interactions between JNK1 and JNK2 is in obesity and insulin resistance, " Proceedings of the National Academy of Sciences of the United States of Americ, vol. 132, no. 2, pp. 311-322, 2005.