메뉴 건너뛰기




Volumn 8, Issue 10, 2015, Pages 12869-12876

Overexpression of BRCA1 attenuates the sensitivity of PC9 cells to gefitinib

Author keywords

BRCA1; Cell proliferation; Gefitinib

Indexed keywords

ANTINEOPLASTIC AGENT; BRCA1 PROTEIN; BRCA1 PROTEIN, HUMAN; GEFITINIB; QUINAZOLINE DERIVATIVE;

EID: 84991625853     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (28)
  • 2
    • 84866608818 scopus 로고    scopus 로고
    • Links between genome integrity and BRCA1 tumor suppression
    • Li M, Greenberg R. Links between genome integrity and BRCA1 tumor suppression. Trends Biochem Sci 2012; 37: 418-424.
    • (2012) Trends Biochem Sci , vol.37 , pp. 418-424
    • Li, M.1    Greenberg, R.2
  • 3
    • 77649131406 scopus 로고    scopus 로고
    • Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
    • Moynahan ME, Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol 2010; 11: 196-207.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 196-207
    • Moynahan, M.E.1    Jasin, M.2
  • 4
    • 84926432359 scopus 로고    scopus 로고
    • Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins
    • Prakash R, Zhang Y, Feng W, Jasin M. Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins. Cold Spring Harb Perspect Biol 2015; 7: a016600.
    • (2015) Cold Spring Harb Perspect Biol , vol.7 , pp. a016600
    • Prakash, R.1    Zhang, Y.2    Feng, W.3    Jasin, M.4
  • 5
    • 77957975815 scopus 로고    scopus 로고
    • Purified human BRCA2 stimulates RAD51-mediated recombination
    • Jensen RB, Carreira A, Kowalczykowski SC. Purified human BRCA2 stimulates RAD51-mediated recombination. Nature 2010; 467: 678-683.
    • (2010) Nature , vol.467 , pp. 678-683
    • Jensen, R.B.1    Carreira, A.2    Kowalczykowski, S.C.3
  • 6
    • 77957804215 scopus 로고    scopus 로고
    • Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
    • Liu J, Doty T, Gibson B, Heyer WD. Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nat Struct Mol Biol 2010; 17: 1260-1262.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 1260-1262
    • Liu, J.1    Doty, T.2    Gibson, B.3    Heyer, W.D.4
  • 8
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273: 5858-5868.
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 9
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995; 19: 183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 12
    • 84934292801 scopus 로고    scopus 로고
    • Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin
    • Oser MG, Niederst MJ, Sequist LV, Engelman JA. Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin. Lancet Oncol 2015; 16: e165-172.
    • (2015) Lancet Oncol , vol.16 , pp. e165-e172
    • Oser, M.G.1    Niederst, M.J.2    Sequist, L.V.3    Engelman, J.A.4
  • 15
    • 47949126508 scopus 로고    scopus 로고
    • Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of Head and Neck cancers
    • Abu-Ali S, Fotovati A, Shirasuna K. Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of Head and Neck cancers. Mol Cancer 2008; 7: 47.
    • (2008) Mol Cancer , vol.7 , pp. 47
    • Abu-Ali, S.1    Fotovati, A.2    Shirasuna, K.3
  • 16
    • 79551510855 scopus 로고    scopus 로고
    • EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment
    • Liccardi G, Hartley JA, Hochhauser D. EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment. Cancer Res 2011; 71: 1103-1114.
    • (2011) Cancer Res , vol.71 , pp. 1103-1114
    • Liccardi, G.1    Hartley, J.A.2    Hochhauser, D.3
  • 18
    • 39749129748 scopus 로고    scopus 로고
    • Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity
    • Tanaka T, unshi A, Brooks C, Liu J, Hobbs ML, Meyn RE. Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity. Clin Cancer Res 2008; 14: 1266-1273.
    • (2008) Clin Cancer Res , vol.14 , pp. 1266-1273
    • Tanaka, T.1    Unshi, A.2    Brooks, C.3    Liu, J.4    Hobbs, M.L.5    Meyn, R.E.6
  • 23
    • 66349096607 scopus 로고    scopus 로고
    • PALB2 is an integral component of the BRCA complex required for homologous recombination repair
    • Sy SM, Huen MS, Chen J. PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci U S A 2009; 106: 7155-7160.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7155-7160
    • Sy, S.M.1    Huen, M.S.2    Chen, J.3
  • 24
    • 66349096607 scopus 로고    scopus 로고
    • PALB2 is an integral component of the BRCA complex required for homologous recombination repair
    • Sy SM, Huen MS, Chen J. PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci U S A 2009; 106: 7155-7160.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7155-7160
    • Sy, S.M.1    Huen, M.S.2    Chen, J.3
  • 25
    • 62549115236 scopus 로고    scopus 로고
    • PALB2 links BRCA1 and BRCA2 in the DNA-damage response
    • Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B, Yu X. PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 2009; 19: 524-529.
    • (2009) Curr Biol , vol.19 , pp. 524-529
    • Zhang, F.1    Ma, J.2    Wu, J.3    Ye, L.4    Cai, H.5    Xia, B.6    Yu, X.7
  • 26
    • 70450270557 scopus 로고    scopus 로고
    • Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C
    • Gildemeister OS, Sage JM, Knight KL. Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. J Biol Chem 2009; 284: 31945-31952.
    • (2009) J Biol Chem , vol.284 , pp. 31945-31952
    • Gildemeister, O.S.1    Sage, J.M.2    Knight, K.L.3
  • 28
    • 85013208728 scopus 로고    scopus 로고
    • Phase IB study of olaparib (AZD2281) plus gefitinib in EGFR-mutant patients (p) with advanced non-small-cell-lung cancer (NSCLC)
    • Campelo R. Phase IB study of olaparib (AZD2281) plus gefitinib in EGFR-mutant patients (p) with advanced non-small-cell-lung cancer (NSCLC). J Clin Oncol 2013; 31 Suppl.
    • (2013) J Clin Oncol , vol.31
    • Campelo, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.