Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NF B Pathway Suppression

Journal of Diabetes Research

Volumn 2016, Issue , 2016, Pages

  Zhou, Zhong'E ^a   Tang, Yong ^a   Jin, Xian ^b   Chen, Chengjun ^b   Lu, Yi ^b   Liu, Liang ^a   Shen, Chengxing ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b The Central Hospital of Minhang District   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CD86 ANTIGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; METFORMIN; TUMOR NECROSIS FACTOR; ADVANCED GLYCATION END PRODUCT RECEPTOR; AGER PROTEIN, MOUSE; ANTIDIABETIC AGENT; CYTOKINE; IL1B PROTEIN, MOUSE; INTERLEUKIN-6, MOUSE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOFLUORESCENCE TEST; INFLAMMATION; MALE; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; GENETICS; MACROPHAGE; METABOLISM;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CYTOKINES; GLYCATION END PRODUCTS, ADVANCED; HYPOGLYCEMIC AGENTS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MACROPHAGES; MALE; METFORMIN; MICE; NF-KAPPA B; RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84991608354     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/4847812     Document Type: Article

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