Epstein-Barr virus associated lymphomas in people with HIV

Current Opinion in HIV and AIDS

Volumn 12, Issue 1, 2017, Pages 39-46

  Carbone, Antonino ^a   Volpi, Chiara C ^b   Gualeni, Ambra V ^b   Gloghini, Annunziata ^b  

^a CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Epstein Barr virus associated lymphoma; Epstein Barr virus related lymphoma; Gamma herpesviruses; HIV; HIV associated lymphoma; Lymphoma

Indexed keywords

CD20 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; KI 67 ANTIGEN; PROTEIN BCL 2; PROTEIN BCL 6; SYNDECAN 1;

BURKITT LYMPHOMA; CLINICAL FEATURE; DISEASE ASSOCIATION; EPSTEIN BARR VIRUS; HODGKIN DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSURVEILLANCE; LARGE CELL LYMPHOMA; LYMPHOMA; PATHOGENESIS; PRIMARY EFFUSION LYMPHOMA; PRIORITY JOURNAL; REVIEW; COMPLICATION; EPSTEIN BARR VIRUS INFECTION; MORTALITY;

EPSTEIN-BARR VIRUS INFECTIONS; HIV INFECTIONS; HUMANS; LYMPHOMA;

EID: 84991503727     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0000000000000333     Document Type: Review

References (40)

1. IARC. Monographs on the evaluation of carcinogenic risks to humans. A review of human carcinogens. Part B: Biological agents/IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Vol. 100, Lyon: 2012.
2. Gloghini A, Dolcetti R, Carbone A. Lymphomas occurring specifically in HIVinfected patients: from pathogenesis to pathology. Semin Cancer Biol 2013; 23:457-467.
3. Dolcetti R, Gloghini A, Caruso A, Carbone A. A lymphomagenic role for HIV beyond immune suppression? Blood 2016; 127:1403-1409.
4. Carbone A, Gloghini A, Dotti G. EBV-associated lymphoproliferative disorders: classification and treatment. Oncologist 2008; 13:577-585.
5. Gloghini A, Carbone A, Pantanowitz L. HIV-associated lymphomas. Atlas Genet Cytogenet Oncol Haematol 2016. [In press]
6. Carbone A, Cesarman E, Spina M, et al. HIV-associated lymphomas and gamma-herpesviruses. Blood 2009; 113:1213-1224.
7. Arvey A, Ojesina AI, Pedamallu CS, et al. The tumor virus landscape of AIDSrelated lymphomas. Blood 2015; 125:e14-e22.
8. Carbone A, Gloghini A, Larocca LM, et al. Expression profile of MUM1/IRF4, BCL-6, and CD138/syndecan-1 defines novel histogenetic subsets of human immunodeficiency virus-related lymphomas. Blood 2001; 97:744-751.
9. Carbone A. Emerging pathways in the development of AIDS-related lymphomas. Lancet Oncol 2003; 4:22-29.
10. Chadburn A, Abdul-Nabi AM, Teruya BS, Lo AA. Lymphoid proliferations associated with human immunodeficiency virus infection. Arch Pathol Lab Med 2013; 137:360-370.
11. Dolcetti R, Giagulli C, Hec W, et al. Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis. Proc Natl Acad Sci 2015; 112:14331-14336.
12. De Paoli P, Carbone A. Microenvironmental abnormalities induced by viral cooperation: impact on lymphomagenesis. Semin Cancer Biol 2015; 34:70-80.
13. Pantanowitz L, Carbone A, Dolcetti R. Microenvironment and HIV-related lymphomagenesis. Semin Cancer Biol 2015; 34:52-57.
14. Dolcetti R. Cross-talk between Epstein-Barr virus and microenvironment in the pathogenesis of lymphomas. Semin Cancer Biol 2015; 34:58-69.
15. Younes A, Carbone A, Johnson P, et al. Hodgkin's lymphoma. In: De Vita VTJ, Lawrence TS, Rosemberg SA, editors. De Vita, Hellman, and Rosenberg's cancer: principles & practice of oncology. Philadelphia, Baltimore, New York: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2014.
16. Martorelli D, Muraro E, Mastorci K, et al. A natural HIV p17 protein variant upregulates the LMP-1 EBV oncoprotein and promotes the growth of EBVinfected B-lymphocytes: implications for EBV-driven lymphomagenesis in the HIV setting. Int J Cancer 2015; 137:1374-1385.
17. Wang H-Y, Wong-Sefidan I, Reid E. Plasmablastic lymphoma. In: Yarchoan E, editor. Cancers in people with HIV and AIDS. New York: Springer; 2014. pp. 223-234.
18. Shiels MS, Pfeiffer RM, Gail MH, et al. Cancer burden in the HIV-infected population in the United States. J Natl Cancer Inst 2011; 103:753-762.
19. Simard EP, Pfeiffer RM, Engels EA. Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States. Cancer 2011; 117:1089-1096.
20. Grulich AE, Vajdic CM. The epidemiology of cancers in human immunodeficiency virus infection and after organ transplantation. Semin Oncol 2015; 42:247-257.
21. Dunleavy K, Wilson WH. How I treat HIV-associated lymphoma. Blood 2012; 119:3245-3255.
22. Carbone A, Vaccher E, Gloghini A, et al. Diagnosis and management of lymphomas and other cancers in HIV-infected patients. Nat Rev Clin Oncol 2014; 11:223-238.
23. Uldrick TS, Little RF. How I treat classical Hodgkin lymphoma in patients infected with human immunodeficiency virus. Blood 2015; 125:1226-1235.
24. Little RF, Pittaluga S, Dunleavy K. Presentation and pathogenesis of B-cell lymphoid cancers associated with HIV infection. In: Yarchoan E, editor. Cancers in people with HIV and AIDS. New York: Springer; 2014. pp. 155-173.
25. Stein H, Dallenbach F. Diffuse large lymphomas of B and T cell type. In: Knowles DM, editor. Neoplastic hematopathology. Baltimore: Williams & Wilkins; 1992. pp. 675-714.
26. Delecluse HJ, Anagnostopoulos I, Dallenbach F, et al. Plasmablastic lymphomas of the oral cavity: a new entity associated with the human immunodeficiency virus infection. Blood 1997; 89:1413-1420.
27. Stein H, Harris NL, Campo E. Plasmablastic lymphoma. In: Swerdlow SH, Campo E, Harris, et al., editors. World Health Organization classification of tumours, pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2008. pp. 256-257.
28. Castillo JJ, Bibas M, Miranda RN. The biology and treatment of plasmablastic lymphoma. Blood 2015; 125:2323-2330.
29. Polizzotto MN, Uldrick TS, Yarchoan R. Multicentric Castleman disease. In: Yarchoan E, editor. Cancers in people with HIV and AIDS. New York: Springer; 2014. pp. 245-260.
30. Carbone A, De Paoli P, Gloghini A, Vaccher E. KSHV-associated multicentric Castleman disease: a tangle of different entities requiring multitarget treatment strategies. Int J Cancer 2015; 137:251-261.
31. Cesarman E, Chang Y, Moore PS, et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 1995; 332:1186-1191.
32. Nador RG, Cesarman E, Chadburn A, et al. Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus. Blood 1996; 88:645-656.
33. Chadburn A, Hyjek E, Mathew S, et al. KSHV-positive solid lymphomas represent an extra-cavitary variant of primary effusion lymphoma. Am J Surg Pathol 2004; 28:1401-1416.
34. Carbone A, Gloghini A, Vaccher E, et al. Kaposi's sarcoma-associated herpesvirus/human herpesvirus type 8-positive solid lymphomas: a tissuebased variant of primary effusion lymphoma. J Mol Diagn 2005; 7:17-27.
35. Klein U, Gloghini A, Gaidano G, et al. Gene expression profile analysis of AIDSrelated primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts. Blood 2003; 101:4115-4121.
36. Fan W, Bubman D, Chadburn A, et al. Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association. J Virol 2005; 79:1244-1251.
37. Carbone A, Cesarman E, Gloghini A, Drexler HG. Understanding pathogenetic aspects and clinical presentation of primary effusion lymphoma through its derived cell lines. AIDS 2010; 24:479-490.
38. Carbone A, Volpi CC, Caccia D, et al. Extracavitary KSHV-positive solid lymphoma: a large B-cell lymphoma within the spectrum of primary effusion lymphoma. Am J Surg Pathol 2013; 37:1460-1461.
39. Gloghini A, Volpi CC, Caccia D, et al. Primary effusion lymphoma: secretome analysis reveals novel candidate biomarkers with potential pathogenetic significance. Am J Pathol 2014; 184:618-630.
40. Fend F, Cabecadas J, Gaulard P, et al. Early lesions in lymphoid neoplasia: conclusions based on the Workshop of the XV. Meeting of the European Association of Hematopathology and the Society of Hematopathology, in Uppsala, Sweden. J Hematopathol 2012; 5:169-199.