Arid5a exacerbates IFN-γ-mediated septic shock by stabilizing T-bet mRNA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 41, 2016, Pages 11543-11548

  Zaman, Mohammad Mahabub Uz ^a   Masuda, Kazuya ^a   Nyati, Kishan Kumar ^a   Dubey, Praveen Kumar ^a   Ripley, Barry ^a   Wang, Kai ^a   Chalise, Jaya Prakash ^a   Higa, Mitsuru ^a   Hanieh, Hamza ^b   Kishimoto, Tadamitsu ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KING FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Arid5a; IFN ; IL 6; Septic shock; T bet

Indexed keywords

ADENINE THYMINE RICH INTERACTIVE DOMAIN CONTAINING PROTEIN 5A; BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 6; MESSENGER RNA; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ARID5A PROTEIN, MOUSE; CYTOKINE; DNA BINDING PROTEIN; LIPOPOLYSACCHARIDE; PROTEIN BINDING; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; IMMUNOREGULATION; LIPOPOLYSACCHARIDE-INDUCED ENDOTOXEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; PROTEIN EXPRESSION; RNA STABILITY; SEPTIC SHOCK; T LYMPHOCYTE ACTIVATION; TH1 CELL; ANIMAL; BLOOD; C57BL MOUSE; CELL SEPARATION; CONFORMATION; CONSERVED SEQUENCE; DEFICIENCY; DISEASE EXACERBATION; FEMALE; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SERODIAGNOSIS;

3' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CELL SEPARATION; CONSERVED SEQUENCE; CYTOKINES; DISEASE PROGRESSION; DNA-BINDING PROTEINS; FEMALE; HEK293 CELLS; HUMANS; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE, INBRED C57BL; NEUTRALIZATION TESTS; NUCLEIC ACID CONFORMATION; PROPIONIBACTERIUM ACNES; PROTEIN BINDING; RNA STABILITY; RNA, MESSENGER; SHOCK, SEPTIC; T-BOX DOMAIN PROTEINS; TH1 CELLS; TRANSCRIPTION FACTORS;

EID: 84991466958     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1613307113     Document Type: Article

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