DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1

Journal of Hematology and Oncology

Volumn 9, Issue 1, 2016, Pages 1-12

  Xu, Jie ^a   Zhang, Wu ^a   Yan, Xiao Jing ^b   Lin, Xue Qiu ^c,d   Li, Wei ^c   Mi, Jian Qing ^a   Li, Jun Min ^a   Zhu, Jiang ^a   Chen, Zhu ^a   Chen, Sai Juan ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d TONGJI UNIVERSITY   (China)

Author keywords

Acute myeloid leukemia; DNMT3A mutation; Extramedullary infiltration; TWIST1

Indexed keywords

DNA METHYLTRANSFERASE 3A; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST1; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; NUCLEAR PROTEIN; TWIST RELATED PROTEIN 1; TWIST1 PROTEIN, HUMAN;

ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CANCER INFILTRATION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DNMT3A GENE; EPITHELIAL MESENCHYMAL TRANSITION; EXTRAMEDULLARY INFILTRATION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MENINX; METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; RNA INTERFERENCE; ACUTE MYELOID LEUKEMIA; ANIMAL; CELL MOTION; GENETICS; MUTATION; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; TUMOR INVASION; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; DNA (CYTOSINE-5-)-METHYLTRANSFERASES; EPITHELIAL-MESENCHYMAL TRANSITION; HETEROGRAFTS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MUTATION; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; TWIST-RELATED PROTEIN 1;

EID: 84991203173     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-016-0337-3     Document Type: Review

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