메뉴 건너뛰기




Volumn 36, Issue 15, 2017, Pages 2095-2104

CXCL2/MIF-CXCR2 signaling promotes the recruitment of myeloid-derived suppressor cells and is correlated with prognosis in bladder cancer

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD33 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR4; CXCL2 CHEMOKINE; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; CXCL2 PROTEIN, HUMAN; ISOMERASE; MACROPHAGE MIGRATION INHIBITION FACTOR; MIF PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR RELA;

EID: 84990957255     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2016.367     Document Type: Article
Times cited : (215)

References (48)
  • 1
    • 84924720760 scopus 로고    scopus 로고
    • Current and recent clinical trials for perioperative systemic therapy for muscle invasive bladder cancer: A systematic review
    • Vashistha V, Quinn DI, Dorff TB, Daneshmand S. Current and recent clinical trials for perioperative systemic therapy for muscle invasive bladder cancer: a systematic review. BMC Cancer 2014; 14: 966.
    • (2014) BMC Cancer , vol.14 , pp. 966
    • Vashistha, V.1    Quinn, D.I.2    Dorff, T.B.3    Daneshmand, S.4
  • 2
    • 84893808963 scopus 로고    scopus 로고
    • The future of bladder cancer care in the USA
    • Kaplan AL, Litwin MS, Chamie K. The future of bladder cancer care in the USA. Nat Rev Urol 2014; 11: 59-62.
    • (2014) Nat Rev Urol , vol.11 , pp. 59-62
    • Kaplan, A.L.1    Litwin, M.S.2    Chamie, K.3
  • 3
    • 84896445750 scopus 로고    scopus 로고
    • Radical cystectomy for bladder cancer: Oncologic outcome in 271 Chinese patients
    • Zhang ZL, Dong P, Li YH, Liu ZW, Yao K, Han H et al. Radical cystectomy for bladder cancer: oncologic outcome in 271 Chinese patients. Chin J Cancer 2014; 33: 165-171.
    • (2014) Chin J Cancer , vol.33 , pp. 165-171
    • Zhang, Z.L.1    Dong, P.2    Li, Y.H.3    Liu, Z.W.4    Yao, K.5    Han, H.6
  • 5
    • 84897114969 scopus 로고    scopus 로고
    • The mechanism of action of BCG therapy for bladder cancer-a current perspective
    • Redelman-Sidi G, Glickman MS, Bochner BH. The mechanism of action of BCG therapy for bladder cancer-a current perspective. Nat Rev Urol 2014; 11: 153-162.
    • (2014) Nat Rev Urol , vol.11 , pp. 153-162
    • Redelman-Sidi, G.1    Glickman, M.S.2    Bochner, B.H.3
  • 6
    • 84923186335 scopus 로고    scopus 로고
    • Immunotherapy: PD-1-PD-L1 axis: Efficient checkpoint blockade against cancer
    • Errico A. Immunotherapy: PD-1-PD-L1 axis: efficient checkpoint blockade against cancer. Nat Rev Clin Oncol 2015; 12: 63.
    • (2015) Nat Rev Clin Oncol , vol.12 , pp. 63
    • Errico, A.1
  • 8
    • 34347340406 scopus 로고    scopus 로고
    • Focus on TILs: Prognostic significance of tumor infiltrating lymphocytes in human bladder cancer
    • Liakou CI, Narayanan S, Ng Tang D, Logothetis CJ, Sharma P. Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in human bladder cancer. Cancer Immun 2007; 7: 10.
    • (2007) Cancer Immun , vol.7 , pp. 10
    • Liakou, C.I.1    Narayanan, S.2    Ng Tang, D.3    Logothetis, C.J.4    Sharma, P.5
  • 9
    • 80053200887 scopus 로고    scopus 로고
    • Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer
    • Eruslanov E, Neuberger M, Daurkin I, Perrin GQ, Algood C, Dahm P et al. Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer. Int J Cancer 2012; 130: 1109-1119.
    • (2012) Int J Cancer , vol.130 , pp. 1109-1119
    • Eruslanov, E.1    Neuberger, M.2    Daurkin, I.3    Perrin, G.Q.4    Algood, C.5    Dahm, P.6
  • 10
    • 84950123685 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in gastric cancer
    • Huang L, Wu RL, Xu AM. Epithelial-mesenchymal transition in gastric cancer. Am J Transl Res 2015; 7: 2141-2158.
    • (2015) Am J Transl Res , vol.7 , pp. 2141-2158
    • Huang, L.1    Wu, R.L.2    Xu, A.M.3
  • 11
    • 34848887822 scopus 로고    scopus 로고
    • Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy
    • Talmadge JE. Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin Cancer Res 2007; 13: 5243-5248.
    • (2007) Clin Cancer Res , vol.13 , pp. 5243-5248
    • Talmadge, J.E.1
  • 12
    • 84957582223 scopus 로고    scopus 로고
    • Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer
    • Dubeykovskaya Z, Si Y, Chen X, Worthley DL, Renz BW, Urbanska AM et al. Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nat Commun 2016; 7: 10517.
    • (2016) Nat Commun , vol.7 , pp. 10517
    • Dubeykovskaya, Z.1    Si, Y.2    Chen, X.3    Worthley, D.L.4    Renz, B.W.5    Urbanska, A.M.6
  • 13
    • 84953215779 scopus 로고    scopus 로고
    • Influential factors and synergies for radiationgene therapy on cancer
    • Lin M, Huang J, Shi Y, Xiao Y, Guo T. Influential factors and synergies for radiationgene therapy on cancer. Anal Cell Pathol 2015; 2015: 313145.
    • (2015) Anal Cell Pathol , vol.2015 , pp. 313145
    • Lin, M.1    Huang, J.2    Shi, Y.3    Xiao, Y.4    Guo, T.5
  • 14
    • 84939442067 scopus 로고    scopus 로고
    • ROR1C regulates differentiation of myeloid-derived suppressor cells
    • Gabrilovich D, Nefedova Y. ROR1C regulates differentiation of myeloid-derived suppressor cells. Cancer Cell 2015; 28: 147-149.
    • (2015) Cancer Cell , vol.28 , pp. 147-149
    • Gabrilovich, D.1    Nefedova, Y.2
  • 15
    • 84901334642 scopus 로고    scopus 로고
    • Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy
    • Highfill SL, Cui Y, Giles AJ, Smith JP, Zhang H, Morse E et al. Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. Sci Transl Med 2014; 6: 237ra267.
    • (2014) Sci Transl Med , vol.6 , pp. 237ra267
    • Highfill, S.L.1    Cui, Y.2    Giles, A.J.3    Smith, J.P.4    Zhang, H.5    Morse, E.6
  • 16
    • 84891836500 scopus 로고    scopus 로고
    • CXCR2-mediated tumorassociated neutrophil recruitment is regulated by IFN-ß
    • Jablonska J, Wu CF, Andzinski L, Leschner S, Weiss S. CXCR2-mediated tumorassociated neutrophil recruitment is regulated by IFN-ß. Int J Cancer 2014; 134: 1346-1358.
    • (2014) Int J Cancer , vol.134 , pp. 1346-1358
    • Jablonska, J.1    Wu, C.F.2    Andzinski, L.3    Leschner, S.4    Weiss, S.5
  • 17
    • 34248328368 scopus 로고    scopus 로고
    • CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers
    • Huang B, Lei Z, Zhao J, Gong W, Liu J, Chen Z et al. CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers. Cancer Lett 2007; 252: 86-92.
    • (2007) Cancer Lett , vol.252 , pp. 86-92
    • Huang, B.1    Lei, Z.2    Zhao, J.3    Gong, W.4    Liu, J.5    Chen, Z.6
  • 18
    • 84954053129 scopus 로고    scopus 로고
    • Targeting YAP-dependent MDSC infiltration impairs tumor progression
    • Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S et al. Targeting YAP-dependent MDSC infiltration impairs tumor progression. Cancer Disc 2016; 6: 80-95.
    • (2016) Cancer Disc , vol.6 , pp. 80-95
    • Wang, G.1    Lu, X.2    Dey, P.3    Deng, P.4    Wu, C.C.5    Jiang, S.6
  • 19
    • 84896726330 scopus 로고    scopus 로고
    • Alphagalactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3
    • Huang JR, Tsai YC, Chang YJ, Wu JC, Hung JT, Lin KH et al. Alphagalactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3. J Immunol 2014; 192: 1972-1981.
    • (2014) J Immunol , vol.192 , pp. 1972-1981
    • Huang, J.R.1    Tsai, Y.C.2    Chang, Y.J.3    Wu, J.C.4    Hung, J.T.5    Lin, K.H.6
  • 20
    • 77953616751 scopus 로고    scopus 로고
    • Regulation of Toll-like receptor-induced chemokine production in murine dendritic cells by mitogen-activated protein kinases
    • Mitchell D, Olive C. Regulation of Toll-like receptor-induced chemokine production in murine dendritic cells by mitogen-activated protein kinases. Mol Immunol 2010; 47: 2065-2073.
    • (2010) Mol Immunol , vol.47 , pp. 2065-2073
    • Mitchell, D.1    Olive, C.2
  • 21
    • 85017310284 scopus 로고    scopus 로고
    • Role of inflammation and inflammatory mediators in colorectal cancer
    • Dubois RN. Role of inflammation and inflammatory mediators in colorectal cancer. Trans Am Clin Climatol Assoc 2014; 125: 358-372.
    • (2014) Trans Am Clin Climatol Assoc , vol.125 , pp. 358-372
    • Dubois, R.N.1
  • 22
    • 84884752495 scopus 로고    scopus 로고
    • Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling
    • Fang LY, Izumi K, Lai KP, Liang L, Li L, Miyamoto H et al. Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling. Cancer Res 2013; 73: 5633-5646.
    • (2013) Cancer Res , vol.73 , pp. 5633-5646
    • Fang, L.Y.1    Izumi, K.2    Lai, K.P.3    Liang, L.4    Li, L.5    Miyamoto, H.6
  • 23
    • 79960411324 scopus 로고    scopus 로고
    • CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
    • Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 2011; 475: 222-225.
    • (2011) Nature , vol.475 , pp. 222-225
    • Qian, B.Z.1    Li, J.2    Zhang, H.3    Kitamura, T.4    Zhang, J.5    Campion, L.R.6
  • 24
    • 84924258438 scopus 로고    scopus 로고
    • Stromal-dependent tumor promotion by MIF family members
    • Mitchell RA, Yaddanapudi K. Stromal-dependent tumor promotion by MIF family members. Cell Signal 2014; 26: 2969-2978.
    • (2014) Cell Signal , vol.26 , pp. 2969-2978
    • Mitchell, R.A.1    Yaddanapudi, K.2
  • 25
    • 33846435328 scopus 로고    scopus 로고
    • Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization
    • Winner M, Koong AC, Rendon BE, Zundel W, Mitchell RA. Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization. Cancer Res 2007; 67: 186-193.
    • (2007) Cancer Res , vol.67 , pp. 186-193
    • Winner, M.1    Koong, A.C.2    Rendon, B.E.3    Zundel, W.4    Mitchell, R.A.5
  • 26
    • 43549112364 scopus 로고    scopus 로고
    • HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling
    • Scortegagna M, Cataisson C, Martin RJ, Hicklin DJ, Schreiber RD, Yuspa SH et al. HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling. Blood 2008; 111: 3343-3354.
    • (2008) Blood , vol.111 , pp. 3343-3354
    • Scortegagna, M.1    Cataisson, C.2    Martin, R.J.3    Hicklin, D.J.4    Schreiber, R.D.5    Yuspa, S.H.6
  • 27
    • 85017330797 scopus 로고    scopus 로고
    • Tumor-induced myeloidderived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer
    • OuYang LY, Wu XJ, Ye SB, Zhang RX, Li ZL, Liao W et al. Tumor-induced myeloidderived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer. J Transl Med 2015; 13: 47.
    • (2015) J Transl Med , vol.13 , pp. 47
    • OuYang, L.Y.1    Wu, X.J.2    Ye, S.B.3    Zhang, R.X.4    Li, Z.L.5    Liao, W.6
  • 29
    • 84911991603 scopus 로고    scopus 로고
    • Phenotypes, accumulation, and functions of myeloidderived suppressor cells and associated treatment strategies in cancer patients
    • Jiang J, Guo W, Liang X. Phenotypes, accumulation, and functions of myeloidderived suppressor cells and associated treatment strategies in cancer patients. Hum Immunol 2014; 75: 1128-1137.
    • (2014) Hum Immunol , vol.75 , pp. 1128-1137
    • Jiang, J.1    Guo, W.2    Liang, X.3
  • 30
    • 84884354300 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2
    • Cui TX, Kryczek I, Zhao L, Zhao E, Kuick R, Roh MH et al. Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2. Immunity 2013; 39: 611-621.
    • (2013) Immunity , vol.39 , pp. 611-621
    • Cui, T.X.1    Kryczek, I.2    Zhao, L.3    Zhao, E.4    Kuick, R.5    Roh, M.H.6
  • 31
    • 84977103128 scopus 로고    scopus 로고
    • Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab
    • Santegoets SJ, Stam AG, Lougheed SM, Gall H, Jooss K, Sacks N et al. Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab. J Immunother Cancer 2014; 2: 31.
    • (2014) J Immunother Cancer , vol.2 , pp. 31
    • Santegoets, S.J.1    Stam, A.G.2    Lougheed, S.M.3    Gall, H.4    Jooss, K.5    Sacks, N.6
  • 32
    • 84937519151 scopus 로고    scopus 로고
    • CCL2 promotes colorectal carcinogenesis by enhancing polymorphonuclear myeloid-derived suppressor cell population and function
    • Chun E, Lavoie S, Michaud M, Gallini CA, Kim J, Soucy G et al. CCL2 promotes colorectal carcinogenesis by enhancing polymorphonuclear myeloid-derived suppressor cell population and function. Cell Rep 2015; 12: 244-257.
    • (2015) Cell Rep , vol.12 , pp. 244-257
    • Chun, E.1    Lavoie, S.2    Michaud, M.3    Gallini, C.A.4    Kim, J.5    Soucy, G.6
  • 34
    • 84900482064 scopus 로고    scopus 로고
    • GammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer
    • Wu P, Wu D, Ni C, Ye J, Chen W, Hu G et al. GammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. Immunity 2014; 40: 785-800.
    • (2014) Immunity , vol.40 , pp. 785-800
    • Wu, P.1    Wu, D.2    Ni, C.3    Ye, J.4    Chen, W.5    Hu, G.6
  • 35
    • 84902158905 scopus 로고    scopus 로고
    • Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/alphaCD40 therapy
    • Weiss JM, Subleski JJ, Back T, Chen X, Watkins SK, Yagita H et al. Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/alphaCD40 therapy. J Immunol 2014; 192: 5821-5829.
    • (2014) J Immunol , vol.192 , pp. 5821-5829
    • Weiss, J.M.1    Subleski, J.J.2    Back, T.3    Chen, X.4    Watkins, S.K.5    Yagita, H.6
  • 36
    • 84880072604 scopus 로고    scopus 로고
    • Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms
    • Mao Y, Poschke I, Wennerberg E, Pico de Coana Y, Egyhazi Brage S, Schultz I et al. Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms. Cancer Res 2013; 73: 3877-3887.
    • (2013) Cancer Res , vol.73 , pp. 3877-3887
    • Mao, Y.1    Poschke, I.2    Wennerberg, E.3    Pico De Coana, Y.4    Egyhazi Brage, S.5    Schultz, I.6
  • 37
    • 84875462761 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer
    • Yu J, Du W, Yan F, Wang Y, Li H, Cao S et al. Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. J Immunol 2013; 190: 3783-3797.
    • (2013) J Immunol , vol.190 , pp. 3783-3797
    • Yu, J.1    Du, W.2    Yan, F.3    Wang, Y.4    Li, H.5    Cao, S.6
  • 38
    • 84872172395 scopus 로고    scopus 로고
    • Increased myeloidderived suppressor cells in gastric cancer correlate with cancer stage and plasma S100A8/A9 proinflammatory proteins
    • Wang L, Chang EW, Wong SC, Ong SM, Chong DQ, Ling KL. Increased myeloidderived suppressor cells in gastric cancer correlate with cancer stage and plasma S100A8/A9 proinflammatory proteins. J Immunol 2013; 190: 794-804.
    • (2013) J Immunol , vol.190 , pp. 794-804
    • Wang, L.1    Chang, E.W.2    Wong, S.C.3    Ong, S.M.4    Chong, D.Q.5    Ling, K.L.6
  • 39
    • 66949145484 scopus 로고    scopus 로고
    • Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells
    • Corzo CA, Cotter MJ, Cheng P, Cheng F, Kusmartsev S, Sotomayor E et al. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. J Immunol 2009; 182: 5693-5701.
    • (2009) J Immunol , vol.182 , pp. 5693-5701
    • Corzo, C.A.1    Cotter, M.J.2    Cheng, P.3    Cheng, F.4    Kusmartsev, S.5    Sotomayor, E.6
  • 40
    • 65549141834 scopus 로고    scopus 로고
    • The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies
    • Ozao-Choy J, Ma G, Kao J, Wang GX, Meseck M, Sung M et al. The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Res 2009; 69: 2514-2522.
    • (2009) Cancer Res , vol.69 , pp. 2514-2522
    • Ozao-Choy, J.1    Ma, G.2    Kao, J.3    Wang, G.X.4    Meseck, M.5    Sung, M.6
  • 41
    • 84899753178 scopus 로고    scopus 로고
    • PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
    • Noman MZ, Desantis G, Janji B, Hasmim M, Karray S, Dessen P et al. PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation. J Exp Med 2014; 211: 781-790.
    • (2014) J Exp Med , vol.211 , pp. 781-790
    • Noman, M.Z.1    Desantis, G.2    Janji, B.3    Hasmim, M.4    Karray, S.5    Dessen, P.6
  • 42
    • 84947032530 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: A novel prognostic indicator
    • Zhang H, Li ZL, Ye SB, Ouyang LY, Chen YS, He J et al. Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator. Cancer Immunol Immunother 2015; 64: 1587-1599.
    • (2015) Cancer Immunol Immunother , vol.64 , pp. 1587-1599
    • Zhang, H.1    Li, Z.L.2    Ye, S.B.3    Ouyang, L.Y.4    Chen, Y.S.5    He, J.6
  • 43
    • 84871330172 scopus 로고    scopus 로고
    • Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice
    • Shang K, Bai YP, Wang C, Wang Z, Gu HY, Du X et al. Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice. PLoS One 2012; 7: e51848.
    • (2012) PLoS One , vol.7 , pp. e51848
    • Shang, K.1    Bai, Y.P.2    Wang, C.3    Wang, Z.4    Gu, H.Y.5    Du, X.6
  • 44
    • 57149106131 scopus 로고    scopus 로고
    • TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche
    • Yamamoto M, Kikuchi H, Ohta M, Kawabata T, Hiramatsu Y, Kondo K et al. TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche. Cancer Res 2008; 68: 9754-9762.
    • (2008) Cancer Res , vol.68 , pp. 9754-9762
    • Yamamoto, M.1    Kikuchi, H.2    Ohta, M.3    Kawabata, T.4    Hiramatsu, Y.5    Kondo, K.6
  • 45
    • 84930960083 scopus 로고    scopus 로고
    • Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK signalling
    • Thummuri D, Jeengar MK, Shrivastava S, Nemani H, Ramavat RN, Chaudhari P et al. Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK signalling. Pharmacol Res 2015; 99: 63-73.
    • (2015) Pharmacol Res , vol.99 , pp. 63-73
    • Thummuri, D.1    Jeengar, M.K.2    Shrivastava, S.3    Nemani, H.4    Ramavat, R.N.5    Chaudhari, P.6
  • 46
    • 30444459066 scopus 로고    scopus 로고
    • MyD88 mediates neutrophil recruitment initiated by IL-1 R but not TLR2 activation in immunity against Staphylococcus aureus
    • Miller LS, O'Connell RM, Gutierrez MA, Pietras EM, Shahangian A, Gross CE et al. MyD88 mediates neutrophil recruitment initiated by IL-1 R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity 2006; 24: 79-91.
    • (2006) Immunity , vol.24 , pp. 79-91
    • Miller, L.S.1    O'Connell, R.M.2    Gutierrez, M.A.3    Pietras, E.M.4    Shahangian, A.5    Gross, C.E.6
  • 47
    • 84876146710 scopus 로고    scopus 로고
    • Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells
    • Hong EH, Chang SY, Lee BR, Kim YS, Lee JM, Kang CY et al. Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells. Int J Cancer 2013; 132: 2839-2848.
    • (2013) Int J Cancer , vol.132 , pp. 2839-2848
    • Hong, E.H.1    Chang, S.Y.2    Lee, B.R.3    Kim, Y.S.4    Lee, J.M.5    Kang, C.Y.6
  • 48
    • 84941795187 scopus 로고    scopus 로고
    • COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells
    • Li ZL, Ye SB, OuYang LY, Zhang H, Chen YS, He J et al. COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells. Oncoimmunology 2015; 4: e1044712.
    • (2015) Oncoimmunology , vol.4 , pp. e1044712
    • Li, Z.L.1    Ye, S.B.2    OuYang, L.Y.3    Zhang, H.4    Chen, Y.S.5    He, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.