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Volumn 2016, Issue , 2016, Pages

Gene × Environment Interactions in Schizophrenia: Evidence from Genetic Mouse Models

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DYSBINDIN; NEU DIFFERENTIATION FACTOR; NUCLEAR RECEPTOR RELATED FACTOR 1; REELIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25;

EID: 84990935792     PISSN: 20905904     EISSN: 16875443     Source Type: Journal    
DOI: 10.1155/2016/2173748     Document Type: Review
Times cited : (35)

References (207)
  • 1
    • 33645217100 scopus 로고    scopus 로고
    • Prenatal infection as a risk factor for schizophrenia
    • A. S. Brown, "Prenatal infection as a risk factor for schizophrenia, " Schizophrenia Bulletin, vol. 32, no. 2, pp. 200-202, 2006.
    • (2006) Schizophrenia Bulletin , vol.32 , Issue.2 , pp. 200-202
    • Brown, A.S.1
  • 2
    • 78249256348 scopus 로고    scopus 로고
    • The environment and susceptibility to schizophrenia
    • A. S. Brown, "The environment and susceptibility to schizophrenia, " Progress in Neurobiology, vol. 93, no. 1, pp. 23-58, 2011.
    • (2011) Progress in Neurobiology , vol.93 , Issue.1 , pp. 23-58
    • Brown, A.S.1
  • 3
    • 77954839370 scopus 로고    scopus 로고
    • Cognition and disability in bipolar disorder: Lessons from schizophrenia research
    • P. D. Harvey, A. P. Wingo, K. E. Burdick, and R. J. Baldessarini, "Cognition and disability in bipolar disorder: lessons from schizophrenia research, " Bipolar Disorders, vol. 12, no. 4, pp. 364-375, 2010.
    • (2010) Bipolar Disorders , vol.12 , Issue.4 , pp. 364-375
    • Harvey, P.D.1    Wingo, A.P.2    Burdick, K.E.3    Baldessarini, R.J.4
  • 4
    • 84859423247 scopus 로고    scopus 로고
    • Schizophrenia and the lifetime trajectory of psychotic illness: Developmental neuroscience and pathobiology, redux
    • A. S. Brown and P. H. Patterson, Eds., Columbia University Press, New York, NY, USA
    • J. L. Waddington, R. J. Hennessy, C. M. P. O'Tuathaigh et al., "Schizophrenia and the lifetime trajectory of psychotic illness: developmental neuroscience and pathobiology, redux, " in The Origins of Schizophrenia, A. S. Brown and P. H. Patterson, Eds., pp. 3-21, Columbia University Press, New York, NY, USA, 2012.
    • (2012) The Origins of Schizophrenia , pp. 3-21
    • Waddington, J.L.1    Hennessy, R.J.2    O'Tuathaigh, C.M.P.3
  • 5
  • 7
    • 80052376956 scopus 로고    scopus 로고
    • The size and burden of mental disorders and other disorders of the brain in Europe 2010
    • H. U. Wittchen, F. Jacobi, J. Rehm et al., "The size and burden of mental disorders and other disorders of the brain in Europe 2010, " European Neuropsychopharmacology, vol. 21, no. 9, pp. 655-679, 2011.
    • (2011) European Neuropsychopharmacology , vol.21 , Issue.9 , pp. 655-679
    • Wittchen, H.U.1    Jacobi, F.2    Rehm, J.3
  • 8
    • 33744795750 scopus 로고    scopus 로고
    • Epidemiology, clinical consequences, and psychosocial treatment of nonadherence in schizophrenia
    • S. Leucht and S. Heres, "Epidemiology, clinical consequences, and psychosocial treatment of nonadherence in schizophrenia, " Journal of Clinical Psychiatry, vol. 67, no. 5, pp. 3-8, 2006.
    • (2006) Journal of Clinical Psychiatry , vol.67 , Issue.5 , pp. 3-8
    • Leucht, S.1    Heres, S.2
  • 9
    • 84922215950 scopus 로고    scopus 로고
    • Recent genetic findings in schizophrenia and their therapeutic relevance
    • P. J. Harrison, "Recent genetic findings in schizophrenia and their therapeutic relevance, " Journal of Psychopharmacology, vol. 29, no. 2, pp. 85-96, 2015.
    • (2015) Journal of Psychopharmacology , vol.29 , Issue.2 , pp. 85-96
    • Harrison, P.J.1
  • 10
    • 84870064466 scopus 로고    scopus 로고
    • Neurodevelopmental model of schizophrenia: Update 2012
    • J. L. Rapoport, J. N. Giedd, and N. Gogtay, "Neurodevelopmental model of schizophrenia: update 2012, " Molecular Psychiatry, vol. 17, no. 12, pp. 1228-1238, 2012.
    • (2012) Molecular Psychiatry , vol.17 , Issue.12 , pp. 1228-1238
    • Rapoport, J.L.1    Giedd, J.N.2    Gogtay, N.3
  • 11
    • 84901608878 scopus 로고    scopus 로고
    • Largescale genomics unveils the genetic architecture of psychiatric disorders
    • J. Gratten, N. R. Wray, M. C. Keller, and P. M. Visscher, "Largescale genomics unveils the genetic architecture of psychiatric disorders, " Nature Neuroscience, vol. 17, no. 6, pp. 782-790, 2014.
    • (2014) Nature Neuroscience , vol.17 , Issue.6 , pp. 782-790
    • Gratten, J.1    Wray, N.R.2    Keller, M.C.3    Visscher, P.M.4
  • 12
    • 0033106050 scopus 로고    scopus 로고
    • Basic concepts in the study of diseases with complex genetics
    • M. Burmeister, "Basic concepts in the study of diseases with complex genetics, " Biological Psychiatry, vol. 45, no. 5, pp. 522-532, 1999.
    • (1999) Biological Psychiatry , vol.45 , Issue.5 , pp. 522-532
    • Burmeister, M.1
  • 13
    • 45749158144 scopus 로고    scopus 로고
    • Psychiatric genetics: Progress amid controversy
    • M. Burmeister, M. G. McInnis, and S. Zöllner, "Psychiatric genetics: progress amid controversy, " Nature Reviews Genetics, vol. 9, no. 7, pp. 527-540, 2008.
    • (2008) Nature Reviews Genetics , vol.9 , Issue.7 , pp. 527-540
    • Burmeister, M.1    McInnis, M.G.2    Zöllner, S.3
  • 14
    • 77955893203 scopus 로고    scopus 로고
    • Misconceptions about gene-environment interactions in psychiatry
    • S. Zammit, M. J. Owen, and G. Lewis, "Misconceptions about gene-environment interactions in psychiatry, " Evidence-Based Mental Health, vol. 13, no. 3, pp. 65-68, 2010.
    • (2010) Evidence-Based Mental Health , vol.13 , Issue.3 , pp. 65-68
    • Zammit, S.1    Owen, M.J.2    Lewis, G.3
  • 15
    • 84908135019 scopus 로고    scopus 로고
    • Practitioner Review: A critical perspective on gene-environment interaction models-what impact should they have on clinical perceptions and practice
    • M. R. Munafò, S. Zammit, and J. Flint, "Practitioner Review: A critical perspective on gene-environment interaction models-what impact should they have on clinical perceptions and practice" Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 55, no. 10, pp. 1092-1101, 2014.
    • (2014) Journal of Child Psychology and Psychiatry and Allied Disciplines , vol.55 , Issue.10 , pp. 1092-1101
    • Munafò, M.R.1    Zammit, S.2    Flint, J.3
  • 16
    • 10644253628 scopus 로고    scopus 로고
    • A review of the evidence from family, twin and adoption studies for a geneticcontribution to adult psychiatric disorders
    • R. A. Shih, P. L. Belmonte, and P. P. Zandi, "A review of the evidence from family, twin and adoption studies for a geneticcontribution to adult psychiatric disorders, " International Review of Psychiatry, vol. 16, no. 4, pp. 260-283, 2004.
    • (2004) International Review of Psychiatry , vol.16 , Issue.4 , pp. 260-283
    • Shih, R.A.1    Belmonte, P.L.2    Zandi, P.P.3
  • 17
    • 0027251609 scopus 로고
    • Genetically mediated vulnerability to schizophrenia
    • C. A. Prescott and I. I. Gottesman, "Genetically mediated vulnerability to schizophrenia, " Psychiatric Clinics of North America, vol. 16, no. 2, pp. 245-267, 1993.
    • (1993) Psychiatric Clinics of North America , vol.16 , Issue.2 , pp. 245-267
    • Prescott, C.A.1    Gottesman, I.I.2
  • 18
    • 0032722572 scopus 로고    scopus 로고
    • Development, disease and degeneration in schizophrenia: A unitary pathophysiological model
    • M. S. Keshavan, "Development, disease and degeneration in schizophrenia: A unitary pathophysiological model, " Journal of Psychiatric Research, vol. 33, no. 6, pp. 513-521, 1999.
    • (1999) Journal of Psychiatric Research , vol.33 , Issue.6 , pp. 513-521
    • Keshavan, M.S.1
  • 19
    • 24344433989 scopus 로고    scopus 로고
    • Association between the neuregulin 1 gene and schizophrenia: A systematic review
    • S. Tosato, P. Dazzan, and D. Collier, "Association between the neuregulin 1 gene and schizophrenia: A systematic review, " Schizophrenia Bulletin, vol. 31, no. 3, pp. 613-617, 2005.
    • (2005) Schizophrenia Bulletin , vol.31 , Issue.3 , pp. 613-617
    • Tosato, S.1    Dazzan, P.2    Collier, D.3
  • 20
    • 84866657557 scopus 로고    scopus 로고
    • Implications of genetic findings for understanding schizophrenia
    • M. J. Owen, "Implications of genetic findings for understanding schizophrenia, " Schizophrenia Bulletin, vol. 38, no. 5, pp. 904-907, 2012.
    • (2012) Schizophrenia Bulletin , vol.38 , Issue.5 , pp. 904-907
    • Owen, M.J.1
  • 22
    • 67651108762 scopus 로고    scopus 로고
    • Genetics of psychosis; Insights from views across the genome
    • M. C. O'Donovan, N. J. Craddock, and M. J. Owen, "Genetics of psychosis; insights from views across the genome, " Human Genetics, vol. 126, no. 1, pp. 3-12, 2009.
    • (2009) Human Genetics , vol.126 , Issue.1 , pp. 3-12
    • O'Donovan, M.C.1    Craddock, N.J.2    Owen, M.J.3
  • 24
    • 84882689092 scopus 로고    scopus 로고
    • Neuregulin 1: A prime candidate for research into gene-environment interactions in schizophrenia Insights from genetic rodent models
    • T. Karl, "Neuregulin 1: A prime candidate for research into gene-environment interactions in schizophrenia Insights from genetic rodent models, " Frontiers in Behavioral Neuroscience, vol. 7, article 106, 2013.
    • (2013) Frontiers in Behavioral Neuroscience , vol.7
    • Karl, T.1
  • 25
    • 84879782139 scopus 로고    scopus 로고
    • Mouse models of gene-environment interactions in schizophrenia
    • G. Kannan, A. Sawa, and M. V. Pletnikov, "Mouse models of gene-environment interactions in schizophrenia, " Neurobiology of Disease, vol. 57, pp. 5-11, 2013.
    • (2013) Neurobiology of Disease , vol.57 , pp. 5-11
    • Kannan, G.1    Sawa, A.2    Pletnikov, M.V.3
  • 26
    • 84949538695 scopus 로고    scopus 로고
    • Closing the translational gap between mutant mouse models and the clinical reality of psychotic illness
    • C. M. O'Tuathaigh and J. L. Waddington, "Closing the translational gap between mutant mouse models and the clinical reality of psychotic illness, " Neuroscience and Biobehavioral Reviews, vol. 58, pp. 19-35, 2015.
    • (2015) Neuroscience and Biobehavioral Reviews , vol.58 , pp. 19-35
    • O'Tuathaigh, C.M.1    Waddington, J.L.2
  • 27
    • 84865159829 scopus 로고    scopus 로고
    • Epigenetics of major psychosis: Progress, problems and perspectives
    • V. Labrie, S. Pai, and A. Petronis, "Epigenetics of major psychosis: progress, problems and perspectives, " Trends in Genetics, vol. 28, no. 9, pp. 427-435, 2012.
    • (2012) Trends in Genetics , vol.28 , Issue.9 , pp. 427-435
    • Labrie, V.1    Pai, S.2    Petronis, A.3
  • 28
    • 84951912775 scopus 로고    scopus 로고
    • Animalmodels of gene-environment interaction in schizophrenia: A dimensional perspective
    • Y. Ayhan, R. McFarland, andM. V. Pletnikov, "Animalmodels of gene-environment interaction in schizophrenia: A dimensional perspective, " Progress in Neurobiology, vol. 136, pp. 1-27, 2016.
    • (2016) Progress in Neurobiology , vol.136 , pp. 1-27
    • Ayhan, Y.1    McFarland, R.2    Pletnikov, M.V.3
  • 29
    • 0035189109 scopus 로고    scopus 로고
    • Paternal factors and schizophrenia risk: De novo mutations and imprinting
    • D. Malaspina, "Paternal factors and schizophrenia risk: de novo mutations and imprinting, " Schizophrenia Bulletin, vol. 27, no. 3, pp. 379-393, 2001.
    • (2001) Schizophrenia Bulletin , vol.27 , Issue.3 , pp. 379-393
    • Malaspina, D.1
  • 30
    • 77951215096 scopus 로고    scopus 로고
    • Advancing paternal and maternal age are both important for autism risk
    • A. Reichenberg, R. Gross, S. Sandin, and E. S. Susser, "Advancing paternal and maternal age are both important for autism risk, " American Journal of Public Health, vol. 100, no. 5, pp. 772-773, 2010.
    • (2010) American Journal of Public Health , vol.100 , Issue.5 , pp. 772-773
    • Reichenberg, A.1    Gross, R.2    Sandin, S.3    Susser, E.S.4
  • 31
    • 84865208871 scopus 로고    scopus 로고
    • Rate of de novo mutations and the importance of father's age to disease risk
    • A. Kong, M. L. Frigge, G. Masson et al., "Rate of de novo mutations and the importance of father's age to disease risk, " Nature, vol. 488, no. 7412, pp. 471-475, 2012.
    • (2012) Nature , vol.488 , Issue.7412 , pp. 471-475
    • Kong, A.1    Frigge, M.L.2    Masson, G.3
  • 32
    • 35648963256 scopus 로고    scopus 로고
    • Aberrant epigenetic regulation could explain the relationship of paternal age to schizophrenia
    • M. C. Perrin, A. S. Brown, and D. Malaspina, "Aberrant epigenetic regulation could explain the relationship of paternal age to schizophrenia, " Schizophrenia Bulletin, vol. 33, no. 6, pp. 1270-1273, 2007.
    • (2007) Schizophrenia Bulletin , vol.33 , Issue.6 , pp. 1270-1273
    • Perrin, M.C.1    Brown, A.S.2    Malaspina, D.3
  • 33
    • 84878253884 scopus 로고    scopus 로고
    • Advanced paternal age is associated with altered DNA methylation at brain-expressed imprinted loci in inbred mice: Implications for neuropsychiatric disease
    • R. G. Smith, A. Reichenberg, R. L. Kember et al., "Advanced paternal age is associated with altered DNA methylation at brain-expressed imprinted loci in inbred mice: implications for neuropsychiatric disease, " Molecular Psychiatry, vol. 18, no. 6, pp. 635-636, 2013.
    • (2013) Molecular Psychiatry , vol.18 , Issue.6 , pp. 635-636
    • Smith, R.G.1    Reichenberg, A.2    Kember, R.L.3
  • 34
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies
    • P. F. Sullivan, K. S. Kendler, and M. C. Neale, "Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies, " Archives of General Psychiatry, vol. 60, no. 12, pp. 1187-1192, 2003.
    • (2003) Archives of General Psychiatry , vol.60 , Issue.12 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 35
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium, "Rare chromosomal deletions and duplications increase risk of schizophrenia, " Nature, vol. 455, pp. 237-241, 2008.
    • (2008) Nature , vol.455 , pp. 237-241
  • 36
    • 49949085933 scopus 로고    scopus 로고
    • Large recurrent microdeletions associated with schizophrenia
    • H. Stefansson, D. Rujescu, S. Cichon et al., "Large recurrent microdeletions associated with schizophrenia, " Nature, vol. 455, pp. 232-236, 2008.
    • (2008) Nature , vol.455 , pp. 232-236
    • Stefansson, H.1    Rujescu, D.2    Cichon, S.3
  • 39
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophreniaassociated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium, "Biological insights from 108 schizophreniaassociated genetic loci, " Nature, vol. 511, pp. 421-427, 2014.
    • (2014) Nature , vol.511 , pp. 421-427
  • 40
    • 84898914426 scopus 로고    scopus 로고
    • Risk genes for schizophrenia: Translational opportunities for drug discovery
    • C. L. Winchester, J. A. Pratt, and B. J. Morris, "Risk genes for schizophrenia: Translational opportunities for drug discovery, " Pharmacology andTherapeutics, vol. 143, no. 1, pp. 34-50, 2014.
    • (2014) Pharmacology AndTherapeutics , vol.143 , Issue.1 , pp. 34-50
    • Winchester, C.L.1    Pratt, J.A.2    Morris, B.J.3
  • 41
    • 84893904007 scopus 로고    scopus 로고
    • A polygenic burden of rare disruptivemutations in schizophrenia
    • S. M. Purcell, J. L. Moran, M. Fromer et al., "A polygenic burden of rare disruptivemutations in schizophrenia, " Nature, vol. 506, no. 7487, pp. 185-190, 2014.
    • (2014) Nature , vol.506 , Issue.7487 , pp. 185-190
    • Purcell, S.M.1    Moran, J.L.2    Fromer, M.3
  • 42
    • 84920646061 scopus 로고    scopus 로고
    • Genetic risk for schizophrenia: Convergence on synaptic pathways involved in plasticity
    • J. Hall, S. Trent, K. L. Thomas, M. C. O'Donovan, and M. J. Owen, "Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity, " Biological Psychiatry, vol. 77, no. 1, pp. 52-58, 2015.
    • (2015) Biological Psychiatry , vol.77 , Issue.1 , pp. 52-58
    • Hall, J.1    Trent, S.2    Thomas, K.L.3    O'Donovan, M.C.4    Owen, M.J.5
  • 43
    • 84883465830 scopus 로고    scopus 로고
    • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
    • Cross-Disorder Group of the Psychiatric Genomics Consortium
    • Cross-Disorder Group of the Psychiatric Genomics Consortium, "Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs, " Nature Genetics, vol. 45, pp. 984-994, 2013.
    • (2013) Nature Genetics , vol.45 , pp. 984-994
  • 44
    • 84928650714 scopus 로고    scopus 로고
    • Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
    • D. M. Ruderfer, A. H. Fanous, S. Ripke et al., "Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia, " Molecular Psychiatry, vol. 19, no. 9, pp. 1017-1024, 2014.
    • (2014) Molecular Psychiatry , vol.19 , Issue.9 , pp. 1017-1024
    • Ruderfer, D.M.1    Fanous, A.H.2    Ripke, S.3
  • 45
    • 84901596062 scopus 로고    scopus 로고
    • Genome-scale neurogenetics: Methodology and meaning
    • S. A. McCarroll, G. Feng, and S. E. Hyman, "Genome-scale neurogenetics: methodology and meaning, " Nature Neuroscience, vol. 17, no. 6, pp. 756-763, 2014.
    • (2014) Nature Neuroscience , vol.17 , Issue.6 , pp. 756-763
    • McCarroll, S.A.1    Feng, G.2    Hyman, S.E.3
  • 46
    • 61849179516 scopus 로고    scopus 로고
    • Early life stress as a risk factor for mental health: Role of neurotrophins from rodents to non-human primates
    • F. Cirulli, N. Francia, A. Berry, L. Aloe, E. Alleva, and S. J. Suomi, "Early life stress as a risk factor for mental health: role of neurotrophins from rodents to non-human primates, " Neuroscience and Biobehavioral Reviews, vol. 33, no. 4, pp. 573-585, 2009.
    • (2009) Neuroscience and Biobehavioral Reviews , vol.33 , Issue.4 , pp. 573-585
    • Cirulli, F.1    Francia, N.2    Berry, A.3    Aloe, L.4    Alleva, E.5    Suomi, S.J.6
  • 47
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • E. J. Nestler and S. E. Hyman, "Animal models of neuropsychiatric disorders, " Nature Neuroscience, vol. 13, no. 10, pp. 1161-1169, 2010.
    • (2010) Nature Neuroscience , vol.13 , Issue.10 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 48
    • 78149462958 scopus 로고    scopus 로고
    • The environment and schizophrenia
    • J. van Os, G. Kenis, and B. P. F. Rutten, "The environment and schizophrenia, " Nature, vol. 468, no. 7321, pp. 203-212, 2010.
    • (2010) Nature , vol.468 , Issue.7321 , pp. 203-212
    • Van Os, J.1    Kenis, G.2    Rutten, B.P.F.3
  • 49
    • 34547851588 scopus 로고    scopus 로고
    • Dissecting cause and effect in the pathogenesis of psychiatric disorders: Genes, environment and behaviour
    • L. Gray and A. J. Hannan, "Dissecting cause and effect in the pathogenesis of psychiatric disorders: genes, environment and behaviour, " Current Molecular Medicine, vol. 7, no. 5, pp. 470-478, 2007.
    • (2007) Current Molecular Medicine , vol.7 , Issue.5 , pp. 470-478
    • Gray, L.1    Hannan, A.J.2
  • 50
    • 78649809112 scopus 로고    scopus 로고
    • Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology
    • B. Abazyan, J. Nomura, G. Kannan et al., "Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology, " Biological Psychiatry, vol. 68, no. 12, pp. 1172-1181, 2010.
    • (2010) Biological Psychiatry , vol.68 , Issue.12 , pp. 1172-1181
    • Abazyan, B.1    Nomura, J.2    Kannan, G.3
  • 51
    • 84963775114 scopus 로고    scopus 로고
    • Acritical period of vulnerability to adolescent stress: Epigeneticmediators in mesocortical dopaminergic neurons
    • M. Niwa, R. S. Lee, T. Tanaka, K. Okada, S. Kano, and A. Sawa, "Acritical period of vulnerability to adolescent stress: epigeneticmediators in mesocortical dopaminergic neurons, " Human Molecular Genetics, vol. 25, no. 7, pp. 1370-1381, 2016.
    • (2016) Human Molecular Genetics , vol.25 , Issue.7 , pp. 1370-1381
    • Niwa, M.1    Lee, R.S.2    Tanaka, T.3    Okada, K.4    Kano, S.5    Sawa, A.6
  • 52
    • 10744221335 scopus 로고    scopus 로고
    • Early and late neurodevelopmental influences in the prodrome to schizophrenia: Contributions of genes, environment, and their interactions
    • T. D. Cannon, T. G. M. Van Erp, C. E. Bearden et al., "Early and late neurodevelopmental influences in the prodrome to schizophrenia: contributions of genes, environment, and their interactions, " Schizophrenia Bulletin, vol. 29, no. 4, pp. 653-669, 2003.
    • (2003) Schizophrenia Bulletin , vol.29 , Issue.4 , pp. 653-669
    • Cannon, T.D.1    Van Erp, T.G.M.2    Bearden, C.E.3
  • 55
    • 84877626914 scopus 로고    scopus 로고
    • Toward the future of psychiatric diagnosis: The seven pillars of RDoC
    • B. N. Cuthbert andT. R. Insel, "Toward the future of psychiatric diagnosis: The seven pillars of RDoC, " BMC Medicine, vol. 11, article 126, 2013.
    • (2013) BMC Medicine , vol.11
    • Cuthbert, B.N.1    Insel, T.R.2
  • 56
    • 71849093384 scopus 로고    scopus 로고
    • Schizophrenia and the city: A review of literature and prospective study of psychosis and urbanicity in Ireland
    • B. D. Kelly, E. O'Callaghan, J. L. Waddington et al., "Schizophrenia and the city: A review of literature and prospective study of psychosis and urbanicity in Ireland, " Schizophrenia Research, vol. 116, no. 1, pp. 75-89, 2010.
    • (2010) Schizophrenia Research , vol.116 , Issue.1 , pp. 75-89
    • Kelly, B.D.1    O'Callaghan, E.2    Waddington, J.L.3
  • 58
    • 0028043537 scopus 로고
    • Schizophrenia and the influenza epidemics of 1954, 1957 and 1959: A southern hemisphere study
    • J. J. McGrath, M. R. Pemberton, J. L. Welham, and R. M. Murray, "Schizophrenia and the influenza epidemics of 1954, 1957 and 1959: A southern hemisphere study, " Schizophrenia Research, vol. 14, no. 1, pp. 1-8, 1994.
    • (1994) Schizophrenia Research , vol.14 , Issue.1 , pp. 1-8
    • McGrath, J.J.1    Pemberton, M.R.2    Welham, J.L.3    Murray, R.M.4
  • 59
    • 0029898371 scopus 로고    scopus 로고
    • Prenatal exposure to the 1957 influenza epidemic and adult schizophrenia: A followup study
    • M. Cannon, D. Cotter, V. P. Coffey et al., "Prenatal exposure to the 1957 influenza epidemic and adult schizophrenia: A followup study, " British Journal of Psychiatry, vol. 168, pp. 368-371, 1996.
    • (1996) British Journal of Psychiatry , vol.168 , pp. 368-371
    • Cannon, M.1    Cotter, D.2    Coffey, V.P.3
  • 60
    • 0033602069 scopus 로고    scopus 로고
    • Effects of family history and place and season of birth on the risk of schizophrenia
    • P. B. Mortensen, C. B. Pedersen, T. Westergaard et al., "Effects of family history and place and season of birth on the risk of schizophrenia, "The New England Journal of Medicine, vol. 340, no. 8, pp. 603-608, 1999.
    • (1999) The New England Journal of Medicine , vol.340 , Issue.8 , pp. 603-608
    • Mortensen, P.B.1    Pedersen, C.B.2    Westergaard, T.3
  • 61
    • 40849145994 scopus 로고    scopus 로고
    • Maternal exposure to herpes simplex virus and risk of psychosis among adult offspring
    • S. L. Buka, T. D. Cannon, E. F. Torrey, andR. H. Yolken, "Maternal exposure to herpes simplex virus and risk of psychosis among adult offspring, " Biological Psychiatry, vol. 63, no. 8, pp. 809-815, 2008.
    • (2008) Biological Psychiatry , vol.63 , Issue.8 , pp. 809-815
    • Buka, S.L.1    Cannon, T.D.2    Torrey, E.F.3    Yolken, R.H.4
  • 62
    • 77649167678 scopus 로고    scopus 로고
    • Prenatal infection and schizophrenia: A review of epidemiologic and translational studies
    • A. S. Brown and E. J. Derkits, "Prenatal infection and schizophrenia: A review of epidemiologic and translational studies, " The American Journal of Psychiatry, vol. 167, no. 3, pp. 261-280, 2010.
    • (2010) The American Journal of Psychiatry , vol.167 , Issue.3 , pp. 261-280
    • Brown, A.S.1    Derkits, E.J.2
  • 63
    • 23244437953 scopus 로고    scopus 로고
    • Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia
    • U. Meyer, J. Feldon, M. Schedlowski, and B. K. Yee, "Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia, "Neuroscience and Biobehavioral Reviews, vol. 29, no. 6, pp. 913-947, 2005.
    • (2005) Neuroscience and Biobehavioral Reviews , vol.29 , Issue.6 , pp. 913-947
    • Meyer, U.1    Feldon, J.2    Schedlowski, M.3    Yee, B.K.4
  • 64
    • 33646831799 scopus 로고    scopus 로고
    • Immunological stress at the maternal-foetal interface: A link between neurodevelopment and adult psychopathology
    • U. Meyer, J. Feldon, M. Schedlowski, and B. K. Yee, "Immunological stress at the maternal-foetal interface: A link between neurodevelopment and adult psychopathology, " Brain, Behavior, and Immunity, vol. 20, no. 4, pp. 378-388, 2006.
    • (2006) Brain, Behavior, and Immunity , vol.20 , Issue.4 , pp. 378-388
    • Meyer, U.1    Feldon, J.2    Schedlowski, M.3    Yee, B.K.4
  • 65
    • 38349115639 scopus 로고    scopus 로고
    • Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling
    • U. Meyer, P. J. Murray, A. Urwyler, B. K. Yee, M. Schedlowski, and J. Feldon, "Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling, " Molecular Psychiatry, vol. 13, no. 2, pp. 208-221, 2008.
    • (2008) Molecular Psychiatry , vol.13 , Issue.2 , pp. 208-221
    • Meyer, U.1    Murray, P.J.2    Urwyler, A.3    Yee, B.K.4    Schedlowski, M.5    Feldon, J.6
  • 66
    • 77957986357 scopus 로고    scopus 로고
    • Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia
    • B. K. Bitanihirwe, D. Peleg-Raibstein, F. Mouttet, J. Feldon, and U. Meyer, "Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia, " Neuropsychopharmacology, vol. 35, no. 12, pp. 2462-2478, 2010.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.12 , pp. 2462-2478
    • Bitanihirwe, B.K.1    Peleg-Raibstein, D.2    Mouttet, F.3    Feldon, J.4    Meyer, U.5
  • 67
    • 0037218688 scopus 로고    scopus 로고
    • Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring
    • L. Shi, S. H. Fatemi, R. W. Sidwell, and P. H. Patterson, "Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring, "The Journal of Neuroscience, vol. 23, no. 1, pp. 297-302, 2003.
    • (2003) The Journal of Neuroscience , vol.23 , Issue.1 , pp. 297-302
    • Shi, L.1    Fatemi, S.H.2    Sidwell, R.W.3    Patterson, P.H.4
  • 68
    • 33646926705 scopus 로고    scopus 로고
    • The time of prenatal immune challenge determines the specificity of inflammationmediated brain and behavioral pathology
    • U. Meyer, M. Nyffeler, A. Engler et al., "The time of prenatal immune challenge determines the specificity of inflammationmediated brain and behavioral pathology, " The Journal of Neuroscience, vol. 26, no. 18, pp. 4752-4762, 2006.
    • (2006) The Journal of Neuroscience , vol.26 , Issue.18 , pp. 4752-4762
    • Meyer, U.1    Nyffeler, M.2    Engler, A.3
  • 69
    • 0642369566 scopus 로고    scopus 로고
    • Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: A novel neurodevelopmental model of schizophrenia
    • L. Zuckerman, M. Rehavi, R. Nachman, and I. Weiner, "Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: A novel neurodevelopmental model of schizophrenia, " Neuropsychopharmacology, vol. 28, no. 10, pp. 1778-1789, 2003.
    • (2003) Neuropsychopharmacology , vol.28 , Issue.10 , pp. 1778-1789
    • Zuckerman, L.1    Rehavi, M.2    Nachman, R.3    Weiner, I.4
  • 70
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • S. E. P. Smith, J. Li, K. Garbett, K. Mirnics, and P. H. Patterson, "Maternal immune activation alters fetal brain development through interleukin-6, " The Journal of Neuroscience, vol. 27, no. 40, pp. 10695-10702, 2007.
    • (2007) The Journal of Neuroscience , vol.27 , Issue.40 , pp. 10695-10702
    • Smith, S.E.P.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 71
    • 84858740384 scopus 로고    scopus 로고
    • Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism
    • N. V. Malkova, C. Z. Yu, E. Y. Hsiao, M. J. Moore, and P. H. Patterson, "Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism, " Brain, Behavior, and Immunity, vol. 26, no. 4, pp. 607-616, 2012.
    • (2012) Brain, Behavior, and Immunity , vol.26 , Issue.4 , pp. 607-616
    • Malkova, N.V.1    Yu, C.Z.2    Hsiao, E.Y.3    Moore, M.J.4    Patterson, P.H.5
  • 72
    • 0141993552 scopus 로고    scopus 로고
    • Post-pubertal emergence of disrupted latent inhibition following prenatal immune activation
    • L. Zuckerman and I. Weiner, "Post-pubertal emergence of disrupted latent inhibition following prenatal immune activation, " Psychopharmacology, vol. 169, no. 3-4, pp. 308-313, 2003.
    • (2003) Psychopharmacology , vol.169 , Issue.3-4 , pp. 308-313
    • Zuckerman, L.1    Weiner, I.2
  • 73
    • 84924073241 scopus 로고    scopus 로고
    • Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: Amelioration byCOX-2 inhibition
    • K. Zavitsanou, C. K. Lim, T. Purves-Tyson et al., "Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: Amelioration byCOX-2 inhibition, " Brain, Behavior, and Immunity, vol. 41, no. 1, pp. 173-181, 2014.
    • (2014) Brain, Behavior, and Immunity , vol.41 , Issue.1 , pp. 173-181
    • Zavitsanou, K.1    Lim, C.K.2    Purves-Tyson, T.3
  • 74
    • 80054007975 scopus 로고    scopus 로고
    • Abnormal trajectories of neurodevelopment and behavior following in utero insult in the rat
    • Y. Piontkewitz, M. Arad, and I. Weiner, "Abnormal trajectories of neurodevelopment and behavior following in utero insult in the rat, " Biological Psychiatry, vol. 70, no. 9, pp. 842-851, 2011.
    • (2011) Biological Psychiatry , vol.70 , Issue.9 , pp. 842-851
    • Piontkewitz, Y.1    Arad, M.2    Weiner, I.3
  • 75
    • 84925452526 scopus 로고    scopus 로고
    • The Poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery
    • S. Reisinger, D. Khan, E. Kong, A. Berger, A. Pollak, and D. D. Pollak, "The Poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery, " Pharmacology andTherapeutics, vol. 149, pp. 213-226, 2015.
    • (2015) Pharmacology AndTherapeutics , vol.149 , pp. 213-226
    • Reisinger, S.1    Khan, D.2    Kong, E.3    Berger, A.4    Pollak, A.5    Pollak, D.D.6
  • 77
    • 66949116991 scopus 로고    scopus 로고
    • A two-method meta-analysis of Neuregulin 1(NRG1) association and heterogeneity in schizophrenia
    • Y. G. Gong, C. N. Wu, Q. H. Xing, X. Z. Zhao, J. Zhu, and L. He, "A two-method meta-analysis of Neuregulin 1(NRG1) association and heterogeneity in schizophrenia, " Schizophrenia Research, vol. 111, no. 1-3, pp. 109-114, 2009.
    • (2009) Schizophrenia Research , vol.111 , Issue.1-3 , pp. 109-114
    • Gong, Y.G.1    Wu, C.N.2    Xing, Q.H.3    Zhao, X.Z.4    Zhu, J.5    He, L.6
  • 78
    • 84879415088 scopus 로고    scopus 로고
    • Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: A case-control study and meta-analysis
    • H. C. Loh, P. Y. Tang, S. F. Tee et al., "Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: A case-control study and meta-analysis, " Psychiatry Research, vol. 208, no. 2, pp. 186-188, 2013.
    • (2013) Psychiatry Research , vol.208 , Issue.2 , pp. 186-188
    • Loh, H.C.1    Tang, P.Y.2    Tee, S.F.3
  • 79
    • 33745684066 scopus 로고    scopus 로고
    • Neuregulin 1 and schizophrenia: Genetics, gene expression, and neurobiology
    • P. J. Harrison and A. J. Law, "Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology, " Biological Psychiatry, vol. 60, no. 2, pp. 132-140, 2006.
    • (2006) Biological Psychiatry , vol.60 , Issue.2 , pp. 132-140
    • Harrison, P.J.1    Law, A.J.2
  • 80
    • 43949084738 scopus 로고    scopus 로고
    • Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
    • L. Mei andW.-C. Xiong, "Neuregulin 1 in neural development, synaptic plasticity and schizophrenia, " Nature Reviews Neuroscience, vol. 9, no. 6, pp. 437-452, 2008.
    • (2008) Nature Reviews Neuroscience , vol.9 , Issue.6 , pp. 437-452
    • Mei, L.1    Xiong, W.-C.2
  • 81
    • 37149023773 scopus 로고    scopus 로고
    • Interleukin-1 beta gene polymorphism and its interactions with neuregulin-1 gene polymorphism are associated with schizophrenia
    • K. Hänninen, H. Katila, M. Saarela et al., "Interleukin-1 beta gene polymorphism and its interactions with neuregulin-1 gene polymorphism are associated with schizophrenia, " European Archives of Psychiatry and Clinical Neuroscience, vol. 258, no. 1, pp. 10-15, 2007.
    • (2007) European Archives of Psychiatry and Clinical Neuroscience , vol.258 , Issue.1 , pp. 10-15
    • Hänninen, K.1    Katila, H.2    Saarela, M.3
  • 82
    • 78149407535 scopus 로고    scopus 로고
    • In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation
    • K. Marballi, M. P. Quinones, F. Jimenez et al., "In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation, " Journal of Molecular Medicine, vol. 88, no. 11, pp. 1133-1141, 2010.
    • (2010) Journal of Molecular Medicine , vol.88 , Issue.11 , pp. 1133-1141
    • Marballi, K.1    Quinones, M.P.2    Jimenez, F.3
  • 83
    • 78650083166 scopus 로고    scopus 로고
    • Phenotypic characterization of transgenic mice overexpressing neuregulin-1
    • T. Kato, A. Kasai, M. Mizuno et al., "Phenotypic characterization of transgenic mice overexpressing neuregulin-1, " PLoS ONE, vol. 5, no. 12, Article IDe14185, 2010.
    • (2010) PLoS ONE , vol.5 , Issue.12
    • Kato, T.1    Kasai, A.2    Mizuno, M.3
  • 84
    • 34748906661 scopus 로고    scopus 로고
    • Alteredmotor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: Implications for understanding schizophrenia
    • T. Karl, L. Duffy, A. Scimone, R. P. Harvey, and P. R. Schofield, "Alteredmotor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia, " Genes, Brain and Behavior, vol. 6, no. 7, pp. 677-687, 2007.
    • (2007) Genes, Brain and Behavior , vol.6 , Issue.7 , pp. 677-687
    • Karl, T.1    Duffy, L.2    Scimone, A.3    Harvey, R.P.4    Schofield, P.R.5
  • 85
    • 34249888202 scopus 로고    scopus 로고
    • Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1
    • C. M. P. O'Tuathaigh, D. Babovic, G. J. O'Sullivan et al., "Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1, " Neuroscience, vol. 147, no. 1, pp. 18-27, 2007.
    • (2007) Neuroscience , vol.147 , Issue.1 , pp. 18-27
    • O'Tuathaigh, C.M.P.1    Babovic, D.2    O'Sullivan, G.J.3
  • 86
    • 84859425428 scopus 로고    scopus 로고
    • Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene ™ environment interaction
    • L. Desbonnet, C. O'Tuathaigh, G. Clarke et al., "Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene ™ environment interaction, " Brain, Behavior, and Immunity, vol. 26, no. 4, pp. 660-671, 2012.
    • (2012) Brain, Behavior, and Immunity , vol.26 , Issue.4 , pp. 660-671
    • Desbonnet, L.1    O'Tuathaigh, C.2    Clarke, G.3
  • 87
    • 84855463704 scopus 로고    scopus 로고
    • Neuregulin 1 hypomorphic mutant mice: Enhanced baseline locomotor activity but normal psychotropic druginduced hyperlocomotion and prepulse inhibition regulation
    • M. van den Buuse, L. Wischhof, R. X. Lee, S. Martin, and T. Karl, "Neuregulin 1 hypomorphic mutant mice: enhanced baseline locomotor activity but normal psychotropic druginduced hyperlocomotion and prepulse inhibition regulation, " International Journal of Neuropsychopharmacology, vol. 12, no. 10, pp. 1383-1393, 2009.
    • (2009) International Journal of Neuropsychopharmacology , vol.12 , Issue.10 , pp. 1383-1393
    • Buuse Den Van, M.1    Wischhof, L.2    Lee, R.X.3    Martin, S.4    Karl, T.5
  • 88
    • 79959301242 scopus 로고    scopus 로고
    • Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit
    • T. Karl, T. H. J. Burne, M. Van den Buuse, and R. Chesworth, "Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit" Behavioural Brain Research, vol. 223, no. 2, pp. 336-341, 2011.
    • (2011) Behavioural Brain Research , vol.223 , Issue.2 , pp. 336-341
    • Karl, T.1    Burne, T.H.J.2    Buuse Den Van, M.3    Chesworth, R.4
  • 89
    • 14944350075 scopus 로고    scopus 로고
    • Neuregulin-1 immunoglobulin-like domain mutant mice: Clozapine sensitivity and impaired latent inhibition
    • M. Rimer, D. W. Barrett, M. A. Maldonado, V. M. Vock, and F. Gonzalez-Lima, "Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition, " NeuroReport, vol. 16, no. 3, pp. 271-275, 2005.
    • (2005) NeuroReport , vol.16 , Issue.3 , pp. 271-275
    • Rimer, M.1    Barrett, D.W.2    Maldonado, M.A.3    Vock, V.M.4    Gonzalez-Lima, F.5
  • 90
    • 49049113745 scopus 로고    scopus 로고
    • Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
    • Y.-J. J. Chen, M. A. Johnson, M. D. Lieberman et al., "Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components, " The Journal of Neuroscience, vol. 28, no. 27, pp. 6872-6883, 2008.
    • (2008) The Journal of Neuroscience , vol.28 , Issue.27 , pp. 6872-6883
    • Chen, Y.-J.J.1    Johnson, M.A.2    Lieberman, M.D.3
  • 91
    • 84898470506 scopus 로고    scopus 로고
    • Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophreniarelated cognitive deficits
    • J.-C. Pei, C.-M. Liu, and W.-S. Lai, "Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophreniarelated cognitive deficits, " Frontiers in Behavioral Neuroscience, vol. 8, article 126, 2014.
    • (2014) Frontiers in Behavioral Neuroscience , vol.8
    • Pei, J.-C.1    Liu, C.-M.2    Lai, W.-S.3
  • 92
    • 84905390577 scopus 로고    scopus 로고
    • Phenotypic effects of maternal immune activation and early postnatal milieu in mice mutant for the schizophrenia risk gene neuregulin-1
    • C. O'Leary, L. Desbonnet, N. Clarke et al., "Phenotypic effects of maternal immune activation and early postnatal milieu in mice mutant for the schizophrenia risk gene neuregulin-1, " Neuroscience, vol. 277, pp. 294-305, 2014.
    • (2014) Neuroscience , vol.277 , pp. 294-305
    • O'Leary, C.1    Desbonnet, L.2    Clarke, N.3
  • 93
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
    • D. H. R. Blackwood, A. Fordyce, M. T. Walker, D. M. St. Clair, D. J. Porteous, and W. J. Muir, "Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family, " American Journal ofHuman Genetics, vol. 69, no. 2, pp. 428-433, 2001.
    • (2001) American Journal OfHuman Genetics , vol.69 , Issue.2 , pp. 428-433
    • Blackwood, D.H.R.1    Fordyce, A.2    Walker, M.T.3    St Clair, D.M.4    Porteous, D.J.5    Muir, W.J.6
  • 94
    • 23744517093 scopus 로고    scopus 로고
    • A frameshift mutation in disrupted in schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder
    • N. A. Sachs, A. Sawa, S. E. Holmes, C. A. Ross, L. E. DeLisi, and R. L. Margolis, "A frameshift mutation in disrupted in schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder, "Molecular Psychiatry, vol. 10, no. 8, pp. 758-764, 2005.
    • (2005) Molecular Psychiatry , vol.10 , Issue.8 , pp. 758-764
    • Sachs, N.A.1    Sawa, A.2    Holmes, S.E.3    Ross, C.A.4    DeLisi, L.E.5    Margolis, R.L.6
  • 95
    • 84856118476 scopus 로고    scopus 로고
    • DISC1-binding proteins in neural development, signalling and schizophrenia
    • N. J. Bradshaw and D. J. Porteous, "DISC1-binding proteins in neural development, signalling and schizophrenia, " Neuropharmacology, vol. 62, no. 3, pp. 1230-1241, 2012.
    • (2012) Neuropharmacology , vol.62 , Issue.3 , pp. 1230-1241
    • Bradshaw, N.J.1    Porteous, D.J.2
  • 96
    • 81555203199 scopus 로고    scopus 로고
    • Linking neurodevelopmental and synaptic theories of mental illness through DISC1
    • N. J. Brandon and A. Sawa, "Linking neurodevelopmental and synaptic theories of mental illness through DISC1, " Nature Reviews Neuroscience, vol. 12, no. 12, pp. 707-722, 2011.
    • (2011) Nature Reviews Neuroscience , vol.12 , Issue.12 , pp. 707-722
    • Brandon, N.J.1    Sawa, A.2
  • 97
    • 34247619460 scopus 로고    scopus 로고
    • Behavioral phenotypes of Disc1 missense mutations in mice
    • S. J. Clapcote, T. V. Lipina, J. K. Millar et al., "Behavioral phenotypes of Disc1 missense mutations in mice, " Neuron, vol. 54, no. 3, pp. 387-402, 2007.
    • (2007) Neuron , vol.54 , Issue.3 , pp. 387-402
    • Clapcote, S.J.1    Lipina, T.V.2    Millar, J.K.3
  • 98
    • 35448988145 scopus 로고    scopus 로고
    • Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected bymeasures translatable to humans
    • T. Hikida, H. Jaaro-Peled, S. Seshadri et al., "Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected bymeasures translatable to humans, " Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 36, pp. 14501-14506, 2007.
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.36 , pp. 14501-14506
    • Hikida, T.1    Jaaro-Peled, H.2    Seshadri, S.3
  • 99
    • 36749042144 scopus 로고    scopus 로고
    • Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice
    • W. Li, Y. Zhou, J. D. Jentsch et al., "Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice, " Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 46, pp. 18280-18285, 2007.
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.46 , pp. 18280-18285
    • Li, W.1    Zhou, Y.2    Jentsch, J.D.3
  • 100
    • 44349132300 scopus 로고    scopus 로고
    • A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition
    • M. Kvajo, H. McKellar, P. A. Arguello et al., "A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition, " Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 19, pp. 7076-7081, 2008.
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.19 , pp. 7076-7081
    • Kvajo, M.1    McKellar, H.2    Arguello, P.A.3
  • 101
    • 38349114264 scopus 로고    scopus 로고
    • Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia
    • M. V. Pletnikov, Y. Ayhan, O. Nikolskaia et al., "Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia, " Molecular Psychiatry, vol. 13, no. 2, pp. 173-186, 2008.
    • (2008) Molecular Psychiatry , vol.13 , Issue.2 , pp. 173-186
    • Pletnikov, M.V.1    Ayhan, Y.2    Nikolskaia, O.3
  • 102
    • 58149174266 scopus 로고    scopus 로고
    • Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated DISC1
    • S. Shen, B. Lang, C. Nakamoto et al., "Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated DISC1, " The Journal of Neuroscience, vol. 28, no. 43, pp. 10893-10904, 2008.
    • (2008) The Journal of Neuroscience , vol.28 , Issue.43 , pp. 10893-10904
    • Shen, S.1    Lang, B.2    Nakamoto, C.3
  • 103
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3/-catenin signaling
    • Y. Mao, X. Ge, C. L. Frank et al., "Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3/-catenin signaling, " Cell, vol. 136, no. 6, pp. 1017-1031, 2009.
    • (2009) Cell , vol.136 , Issue.6 , pp. 1017-1031
    • Mao, Y.1    Ge, X.2    Frank, C.L.3
  • 104
    • 84877137928 scopus 로고    scopus 로고
    • Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice
    • T. V. Lipina, C. Zai, D. Hlousek, J. C. Roder, and A. H. C. Wong, "Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice, " The Journal of Neuroscience, vol. 33, no. 18, pp. 7654-7666, 2013.
    • (2013) The Journal of Neuroscience , vol.33 , Issue.18 , pp. 7654-7666
    • Lipina, T.V.1    Zai, C.2    Hlousek, D.3    Roder, J.C.4    Wong, A.H.C.5
  • 105
    • 65549109489 scopus 로고    scopus 로고
    • NeonatalpolyI:Ctreatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood
    • D. Ibi, T. Nagai, Y. Kitahara et al., "NeonatalpolyI:Ctreatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood, " Neuroscience Research, vol. 64, no. 3, pp. 297-305, 2009.
    • (2009) Neuroscience Research , vol.64 , Issue.3 , pp. 297-305
    • Ibi, D.1    Nagai, T.2    Kitahara, Y.3
  • 106
    • 80052023997 scopus 로고    scopus 로고
    • Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment
    • T. Nagai, Y. Kitahara, D. Ibi, T. Nabeshima, A. Sawa, and K. Yamada, "Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment, " Behavioural Brain Research, vol. 225, no. 1, pp. 305-310, 2011.
    • (2011) Behavioural Brain Research , vol.225 , Issue.1 , pp. 305-310
    • Nagai, T.1    Kitahara, Y.2    Ibi, D.3    Nabeshima, T.4    Sawa, A.5    Yamada, K.6
  • 107
    • 84899007371 scopus 로고    scopus 로고
    • Chronic exposure of mutantDISC1 mice to lead produces sex-dependent abnormalities consistent with schizophrenia and related mental disorders: A gene-environment interaction study
    • B. Abazyan, J. Dziedzic, K. Hua et al., "Chronic exposure of mutantDISC1 mice to lead produces sex-dependent abnormalities consistent with schizophrenia and related mental disorders: A gene-environment interaction study, " Schizophrenia Bulletin, vol. 40, no. 3, pp. 575-584, 2014.
    • (2014) Schizophrenia Bulletin , vol.40 , Issue.3 , pp. 575-584
    • Abazyan, B.1    Dziedzic, J.2    Hua, K.3
  • 108
    • 72449191782 scopus 로고    scopus 로고
    • Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons
    • B. Kadkhodaei, T. Ito, E. Joodmardi et al., "Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons, " The Journal of Neuroscience, vol. 29, no. 50, pp. 15923-15932, 2009.
    • (2009) The Journal of Neuroscience , vol.29 , Issue.50 , pp. 15923-15932
    • Kadkhodaei, B.1    Ito, T.2    Joodmardi, E.3
  • 109
    • 34547423806 scopus 로고    scopus 로고
    • Adult mice with reduced Nurr1 expression: An animal modelfor schizophrenia
    • P. Rojas, E. Joodmardi, Y. Hong, T. Perlmann, and S. O. ögren, "Adult mice with reduced Nurr1 expression: An animal modelfor schizophrenia, " Molecular Psychiatry, vol. 12, no. 8, pp. 756-766, 2007.
    • (2007) Molecular Psychiatry , vol.12 , Issue.8 , pp. 756-766
    • Rojas, P.1    Joodmardi, E.2    Hong, Y.3    Perlmann, T.4    Ögren, S.O.5
  • 110
    • 84855646841 scopus 로고    scopus 로고
    • Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments
    • S. Vuillermot, E. Joodmardi, T. Perlmann, S. O. ögren, J. Feldon, and U. Meyer, "Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments, " The Journal of Neuroscience, vol. 32, no. 2, pp. 436-451, 2012.
    • (2012) The Journal of Neuroscience , vol.32 , Issue.2 , pp. 436-451
    • Vuillermot, S.1    Joodmardi, E.2    Perlmann, T.3    Ögren, S.O.4    Feldon, J.5    Meyer, U.6
  • 113
    • 33846795815 scopus 로고    scopus 로고
    • Cannabis and psychosis: An update on course and biological plausiblemechanisms
    • D. Linszen and T. van Amelsvoort, "Cannabis and psychosis: An update on course and biological plausiblemechanisms, " Current Opinion in Psychiatry, vol. 20, no. 2, pp. 116-120, 2007.
    • (2007) Current Opinion in Psychiatry , vol.20 , Issue.2 , pp. 116-120
    • Linszen, D.1    Van Amelsvoort, T.2
  • 114
    • 34447619511 scopus 로고    scopus 로고
    • Cannabis use and risk of psychotic or affective mental health outcomes: A systematic review
    • T. H. Moore, S. Zammit, A. Lingford-Hughes et al., "Cannabis use and risk of psychotic or affective mental health outcomes: A systematic review, " The Lancet, vol. 370, no. 9584, pp. 319-328, 2007.
    • (2007) The Lancet , vol.370 , Issue.9584 , pp. 319-328
    • Moore, T.H.1    Zammit, S.2    Lingford-Hughes, A.3
  • 115
    • 0037240264 scopus 로고    scopus 로고
    • Cannabis dependence and psychotic symptoms in young people
    • D. M. Fergusson, L. J. Horwood, and N. R. Swain-Campbell, "Cannabis dependence and psychotic symptoms in young people, " Psychological Medicine, vol. 33, no. 1, pp. 15-21, 2003.
    • (2003) Psychological Medicine , vol.33 , Issue.1 , pp. 15-21
    • Fergusson, D.M.1    Horwood, L.J.2    Swain-Campbell, N.R.3
  • 116
    • 0037164390 scopus 로고    scopus 로고
    • Cannabis use in adolescence and risk for adult psychosis: Longitudinal prospective study
    • L. Arseneault, M. Cannon, R. Poulton, R. Murray, A. Caspi, and T. E. Moffitt, "Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study, " BritishMedical Journal, vol. 325, no. 7374, pp. 1212-1213, 2002.
    • (2002) BritishMedical Journal , vol.325 , Issue.7374 , pp. 1212-1213
    • Arseneault, L.1    Cannon, M.2    Poulton, R.3    Murray, R.4    Caspi, A.5    Moffitt, T.E.6
  • 117
    • 0442307621 scopus 로고    scopus 로고
    • Causal association between cannabis and psychosis: Examination of the evidence
    • L. Arseneault, M. Cannon, J. Witton, and R. M. Murray, "Causal association between cannabis and psychosis: examination of the evidence, " British Journal of Psychiatry, vol. 184, pp. 110-117, 2004.
    • (2004) British Journal of Psychiatry , vol.184 , pp. 110-117
    • Arseneault, L.1    Cannon, M.2    Witton, J.3    Murray, R.M.4
  • 118
    • 77951853072 scopus 로고    scopus 로고
    • Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults
    • J. McGrath, J. Welham, J. Scott et al., "Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults, " Archives of General Psychiatry, vol. 67, no. 5, pp. 440-447, 2010.
    • (2010) Archives of General Psychiatry , vol.67 , Issue.5 , pp. 440-447
    • McGrath, J.1    Welham, J.2    Scott, J.3
  • 119
    • 84875485080 scopus 로고    scopus 로고
    • Genetic variation underlying psychosis-inducing effects of cannabis: Critical review and future directions
    • J. Decoster, J. van Os, I. Myin-Germeys, M. De Hert, and R. van Winkel, "Genetic variation underlying psychosis-inducing effects of cannabis: critical review and future directions, " Current Pharmaceutical Design, vol. 18, no. 32, pp. 5015-5023, 2012.
    • (2012) Current Pharmaceutical Design , vol.18 , Issue.32 , pp. 5015-5023
    • Decoster, J.1    Van Os, J.2    Myin-Germeys, I.3    De Hert, M.4    Van Winkel, R.5
  • 120
    • 77956400455 scopus 로고    scopus 로고
    • Genome-wide findings in schizophrenia and the role of gene-environment interplay
    • R. Van Winkel, G. Esquivel, G. Kenis et al., "Genome-wide findings in schizophrenia and the role of gene-environment interplay, " CNS Neuroscience and Therapeutics, vol. 16, no. 5, pp. e185-e192, 2010.
    • (2010) CNS Neuroscience and Therapeutics , vol.16 , Issue.5 , pp. e185-e192
    • Van Winkel, R.1    Esquivel, G.2    Kenis, G.3
  • 121
    • 84943531741 scopus 로고    scopus 로고
    • Early cannabis use, polygenic risk score for schizophrenia and brain maturation in adolescence
    • L. French, C. Gray, G. Leonard et al., "Early cannabis use, polygenic risk score for schizophrenia and brain maturation in adolescence, " JAMA Psychiatry, vol. 72, no. 10, pp. 1002-1011, 2015.
    • (2015) JAMA Psychiatry , vol.72 , Issue.10 , pp. 1002-1011
    • French, L.1    Gray, C.2    Leonard, G.3
  • 122
    • 84943525539 scopus 로고    scopus 로고
    • America's cannabis experiment
    • D. Goldman, "America's cannabis experiment, " JAMA Psychiatry, vol. 72, no. 10, pp. 969-970, 2015.
    • (2015) JAMA Psychiatry , vol.72 , Issue.10 , pp. 969-970
    • Goldman, D.1
  • 123
    • 78651274327 scopus 로고    scopus 로고
    • Chronic adolescent exposure to-9-tetrahydrocannabinol in COMT mutant mice: Impact on psychosis-related and other phenotypes
    • C. M. P. O'Tuathaigh, M. Hryniewiecka, A. Behan et al., "Chronic adolescent exposure to-9-tetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes, " Neuropsychopharmacology, vol. 35, no. 11, pp. 2262-2273, 2010.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.11 , pp. 2262-2273
    • O'Tuathaigh, C.M.P.1    Hryniewiecka, M.2    Behan, A.3
  • 124
    • 0642338928 scopus 로고    scopus 로고
    • Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognitionmemory, and theperformance inaprogressive ratio task in adult rats
    • M. Schneider and M. Koch, "Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognitionmemory, and theperformance inaprogressive ratio task in adult rats, " Neuropsychopharmacology, vol. 28, no. 10, pp. 1760-1769, 2003.
    • (2003) Neuropsychopharmacology , vol.28 , Issue.10 , pp. 1760-1769
    • Schneider, M.1    Koch, M.2
  • 125
    • 84978745776 scopus 로고    scopus 로고
    • Adolescent cannabinoid exposure induces a persistent sub-cortical hyper-dopaminergic state and associated molecular adaptations in the prefrontal cortex
    • J. Renard, L. G. Rosen, M. Loureiro et al., "Adolescent cannabinoid exposure induces a persistent sub-cortical hyper-dopaminergic state and associated molecular adaptations in the prefrontal cortex, " Cerebral Cortex, 2016.
    • (2016) Cerebral Cortex
    • Renard, J.1    Rosen, L.G.2    Loureiro, M.3
  • 126
    • 68149158212 scopus 로고    scopus 로고
    • From real-world events to psychosis: The emerging neuropharmacology of delusions
    • P. D. Morrison and R. M. Murray, "From real-world events to psychosis: The emerging neuropharmacology of delusions, " Schizophrenia Bulletin, vol. 35, no. 4, pp. 668-674, 2009.
    • (2009) Schizophrenia Bulletin , vol.35 , Issue.4 , pp. 668-674
    • Morrison, P.D.1    Murray, R.M.2
  • 127
    • 84866630843 scopus 로고    scopus 로고
    • Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans
    • S. Han, B.-Z. Yang, H. R. Kranzler et al., "Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans, " Biological Psychiatry, vol. 72, no. 8, pp. 637-644, 2012.
    • (2012) Biological Psychiatry , vol.72 , Issue.8 , pp. 637-644
    • Han, S.1    Yang, B.-Z.2    Kranzler, H.R.3
  • 128
    • 36248997006 scopus 로고    scopus 로고
    • Heterozygous neuregulin 1 mice display greater baseline and 9-tetrahydrocannabinol-induced c-Fos expression
    • A. A. Boucher, G. E. Hunt, T. Karl, J. Micheau, I. S. McGregor, and J. C. Arnold, "Heterozygous neuregulin 1 mice display greater baseline and 9-tetrahydrocannabinol-induced c-Fos expression, " Neuroscience, vol. 149, no. 4, pp. 861-870, 2007.
    • (2007) Neuroscience , vol.149 , Issue.4 , pp. 861-870
    • Boucher, A.A.1    Hunt, G.E.2    Karl, T.3    Micheau, J.4    McGregor, I.S.5    Arnold, J.C.6
  • 129
    • 34248175418 scopus 로고    scopus 로고
    • Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of 9-tetrahydrocannabinol
    • A. A. Boucher, J. C. Arnold, L. Duffy, P. R. Schofield, J. Micheau, and T. Karl, "Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of 9-tetrahydrocannabinol, " Psychopharmacology, vol. 192, no. 3, pp. 325-336, 2007.
    • (2007) Psychopharmacology , vol.192 , Issue.3 , pp. 325-336
    • Boucher, A.A.1    Arnold, J.C.2    Duffy, L.3    Schofield, P.R.4    Micheau, J.5    Karl, T.6
  • 130
    • 77955471951 scopus 로고    scopus 로고
    • A followup study: Acute behavioural effects of 9-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice
    • L. E. Long, R. Chesworth, J. C. Arnold, and T. Karl, "A followup study: Acute behavioural effects of 9-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice, " Psychopharmacology, vol. 211, no. 3, pp. 277-289, 2010.
    • (2010) Psychopharmacology , vol.211 , Issue.3 , pp. 277-289
    • Long, L.E.1    Chesworth, R.2    Arnold, J.C.3    Karl, T.4
  • 131
    • 79956013167 scopus 로고    scopus 로고
    • The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids
    • A. A. Boucher, G. E. Hunt, J. Micheau et al., "The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids, " International Journal of Neuropsychopharmacology, vol. 14, no. 5, pp. 631-643, 2011.
    • (2011) International Journal of Neuropsychopharmacology , vol.14 , Issue.5 , pp. 631-643
    • Boucher, A.A.1    Hunt, G.E.2    Micheau, J.3
  • 132
    • 84871530475 scopus 로고    scopus 로고
    • Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeatedTHCexposure in adolescence
    • L. E. Long, R. Chesworth, X.-F. Huang, I. S. McGregor, J. C. Arnold, and T. Karl, "Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeatedTHCexposure in adolescence, " International Journal of Neuropsychopharmacology, vol. 16, no. 1, pp. 163-175, 2013.
    • (2013) International Journal of Neuropsychopharmacology , vol.16 , Issue.1 , pp. 163-175
    • Long, L.E.1    Chesworth, R.2    Huang, X.-F.3    McGregor, I.S.4    Arnold, J.C.5    Karl, T.6
  • 133
    • 85081783369 scopus 로고    scopus 로고
    • Novelmolecular changes induced by Nrg1 hypomorphismand Nrg1-cannabinoid interaction in adolescence: A hippocampal proteomic study in mice
    • J. R. Spencer, K. M. E. Darbyshire, A. A. Boucher et al., "Novelmolecular changes induced by Nrg1 hypomorphismand Nrg1-cannabinoid interaction in adolescence: A hippocampal proteomic study in mice, " Frontiers in CellularNeuroscience, vol. 7, article 15, 2013.
    • (2013) Frontiers in CellularNeuroscience , vol.7
    • Spencer, J.R.1    Darbyshire, K.M.E.2    Boucher, A.A.3
  • 134
    • 78650625479 scopus 로고    scopus 로고
    • Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: A preliminary report
    • J. A. S. Crippa, G. N. Derenusson, T. B. Ferrari et al., "Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: A preliminary report, " Journal of Psychopharmacology, vol. 25, no. 1, pp. 121-130, 2011.
    • (2011) Journal of Psychopharmacology , vol.25 , Issue.1 , pp. 121-130
    • Crippa, J.A.S.1    Derenusson, G.N.2    Ferrari, T.B.3
  • 135
    • 84956673537 scopus 로고    scopus 로고
    • Therapeutic potential of cannabinoids in psychosis
    • F. M. Leweke, J. K. Mueller, B. Lange et al., "Therapeutic potential of cannabinoids in psychosis, " Biological Psychiatry, vol. 79, no. 7, pp. 604-612, 2015.
    • (2015) Biological Psychiatry , vol.79 , Issue.7 , pp. 604-612
    • Leweke, F.M.1    Mueller, J.K.2    Lange, B.3
  • 136
    • 84859258164 scopus 로고    scopus 로고
    • Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice
    • L. E. Long, R. Chesworth, X.-F. Huang et al., "Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice, " PLoS ONE, vol. 7, no. 4, Article ID e34129, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Long, L.E.1    Chesworth, R.2    Huang, X.-F.3
  • 137
    • 84934960252 scopus 로고    scopus 로고
    • Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory
    • M. D. Ballinger, A. Saito, B. Abazyan et al., "Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory, " Neurobiology of Disease, vol. 82, pp. 176-184, 2015.
    • (2015) Neurobiology of Disease , vol.82 , pp. 176-184
    • Ballinger, M.D.1    Saito, A.2    Abazyan, B.3
  • 138
    • 31544460943 scopus 로고    scopus 로고
    • A novel protein isoform of catechol O-methyltransferase (COMT): Brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype
    • E. M. Tunbridge, D. R. Weinberger, and P. J. Harrison, "A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype, " Molecular Psychiatry, vol. 11, no. 2, pp. 116-117, 2006.
    • (2006) Molecular Psychiatry , vol.11 , Issue.2 , pp. 116-117
    • Tunbridge, E.M.1    Weinberger, D.R.2    Harrison, P.J.3
  • 139
    • 82455217216 scopus 로고    scopus 로고
    • COMT Val158Met-stress interaction in psychosis: Role of background psychosis risk
    • D. Collip, R. Van Winkel, O. Peerbooms et al., "COMT Val158Met-stress interaction in psychosis: role of background psychosis risk, " CNS Neuroscience and Therapeutics, vol. 17, no. 6, pp. 612-619, 2011.
    • (2011) CNS Neuroscience and Therapeutics , vol.17 , Issue.6 , pp. 612-619
    • Collip, D.1    Van Winkel, R.2    Peerbooms, O.3
  • 140
    • 84877138328 scopus 로고    scopus 로고
    • Gene-environment interaction on cognition: A twin study of childhood maltreatment and COMT variability
    • X. Goldberg, M. Fatjó-Vilas, S. Alemany, I. Nenadic, C. Gastó, and L. Fañanás, "Gene-environment interaction on cognition: A twin study of childhood maltreatment and COMT variability, " Journal of Psychiatric Research, vol. 47, no. 7, pp. 989-994, 2013.
    • (2013) Journal of Psychiatric Research , vol.47 , Issue.7 , pp. 989-994
    • Goldberg, X.1    Fatjó-Vilas, M.2    Alemany, S.3    Nenadic, I.4    Gastó, C.5    Fañanás, L.6
  • 141
    • 84890242585 scopus 로고    scopus 로고
    • Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes
    • S. Alemany, B. Arias, M. Fatjó-Vilas et al., "Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes, " Acta Psychiatrica Scandinavica, vol. 129, no. 1, pp. 54-62, 2014.
    • (2014) Acta Psychiatrica Scandinavica , vol.129 , Issue.1 , pp. 54-62
    • Alemany, S.1    Arias, B.2    Fatjó-Vilas, M.3
  • 142
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene X environment interaction
    • A. Caspi, T. E. Moffitt, M. Cannon et al., "Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction, " Biological Psychiatry, vol. 57, no. 10, pp. 1117-1127, 2005.
    • (2005) Biological Psychiatry , vol.57 , Issue.10 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3
  • 143
    • 84870593059 scopus 로고    scopus 로고
    • Genetic vs. Pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes
    • C. M. P. O'Tuathaigh, G. Clarke, J. Walsh et al., "Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes, " International Journal ofNeuropsychopharmacology, vol. 15, no. 9, pp. 1331-1342, 2012.
    • (2012) International Journal OfNeuropsychopharmacology , vol.15 , Issue.9 , pp. 1331-1342
    • O'Tuathaigh, C.M.P.1    Clarke, G.2    Walsh, J.3
  • 144
    • 84861183838 scopus 로고    scopus 로고
    • Chronic adolescent exposure to delta-9-tetrahydrocannabinol in COMT mutant mice: Impact on indices of dopaminergic, endocannabinoid and GABAergic pathways
    • á. T. Behan, M. Hryniewiecka, C. M. P. O'Tuathaigh et al., "Chronic adolescent exposure to delta-9-tetrahydrocannabinol in COMT mutant mice: impact on indices of dopaminergic, endocannabinoid and GABAergic pathways, " Neuropsychopharmacology, vol. 37, no. 7, pp. 1773-1783, 2012.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.7 , pp. 1773-1783
    • Behan Á, T.1    Hryniewiecka, M.2    O'Tuathaigh, C.M.P.3
  • 145
    • 33746589994 scopus 로고    scopus 로고
    • Stress, the hippocampus and the hypothalamic-pituitary-adrenal axis: Implications for the development of psychotic disorders
    • L. J. Phillips, P. D. McGorry, B. Garner et al., "Stress, the hippocampus and the hypothalamic-pituitary-adrenal axis: implications for the development of psychotic disorders, " Australian and New Zealand Journal of Psychiatry, vol. 40, no. 9, pp. 725-741, 2006.
    • (2006) Australian and New Zealand Journal of Psychiatry , vol.40 , Issue.9 , pp. 725-741
    • Phillips, L.J.1    McGorry, P.D.2    Garner, B.3
  • 146
    • 79952145883 scopus 로고    scopus 로고
    • Longitudinal study of stressful life events and daily stressors among adolescents at high risk for psychotic disorders
    • K. D. Tessner, V. Mittal, and E. F. Walker, "Longitudinal study of stressful life events and daily stressors among adolescents at high risk for psychotic disorders, " Schizophrenia Bulletin, vol. 37, no. 2, pp. 432-441, 2011.
    • (2011) Schizophrenia Bulletin , vol.37 , Issue.2 , pp. 432-441
    • Tessner, K.D.1    Mittal, V.2    Walker, E.F.3
  • 147
    • 84859269675 scopus 로고    scopus 로고
    • Dissociation mediates the relationship between childhood trauma and hallucinationproneness
    • F. Varese, E. Barkus, and R. P. Bentall, "Dissociation mediates the relationship between childhood trauma and hallucinationproneness, " PsychologicalMedicine, vol. 42, no. 5, pp. 1025-1036, 2012.
    • (2012) PsychologicalMedicine , vol.42 , Issue.5 , pp. 1025-1036
    • Varese, F.1    Barkus, E.2    Bentall, R.P.3
  • 148
    • 37249038472 scopus 로고    scopus 로고
    • Hypothesis: Social defeat is a risk factor for schizophrenia
    • J.-P. Selten and E. Cantor-Graae, "Hypothesis: social defeat is a risk factor for schizophrenia" The British Journal of Psychiatry, vol. 191, no. 51, pp. s9-s12, 2007.
    • (2007) The British Journal of Psychiatry , vol.191 , Issue.51 , pp. s9-s12
    • Selten, J.-P.1    Cantor-Graae, E.2
  • 151
    • 32444451651 scopus 로고    scopus 로고
    • Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    • O. Berton, C. A. McClung, R. J. DiLeone et al., "Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress, " Science, vol. 311, no. 5762, pp. 864-868, 2006.
    • (2006) Science , vol.311 , Issue.5762 , pp. 864-868
    • Berton, O.1    McClung, C.A.2    DiLeone, R.J.3
  • 152
    • 35348832393 scopus 로고    scopus 로고
    • Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    • V. Krishnan, M. Han, D. L. Graham et al., "Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions, " Cell, vol. 131, no. 2, pp. 391-404, 2007.
    • (2007) Cell , vol.131 , Issue.2 , pp. 391-404
    • Krishnan, V.1    Han, M.2    Graham, D.L.3
  • 153
    • 84907570931 scopus 로고    scopus 로고
    • Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice
    • T. W. Chohan, A. A. Boucher, J. R. Spencer et al., "Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice, " Schizophrenia Bulletin, vol. 40, no. 6, pp. 1272-1284, 2014.
    • (2014) Schizophrenia Bulletin , vol.40 , Issue.6 , pp. 1272-1284
    • Chohan, T.W.1    Boucher, A.A.2    Spencer, J.R.3
  • 154
    • 84862224816 scopus 로고    scopus 로고
    • Social defeat interacts with Disc1 mutations in the mouse to affect behavior
    • F. N. Haque, T. V. Lipina, J. C. Roder, and A. H. C. Wong, "Social defeat interacts with Disc1 mutations in the mouse to affect behavior, " Behavioural Brain Research, vol. 233, no. 2, pp. 337-344, 2012.
    • (2012) Behavioural Brain Research , vol.233 , Issue.2 , pp. 337-344
    • Haque, F.N.1    Lipina, T.V.2    Roder, J.C.3    Wong, A.H.C.4
  • 155
    • 84872443390 scopus 로고    scopus 로고
    • Adolescent stressinduced epigenetic control of dopaminergic neurons via glucocorticoids
    • M. Niwa, H. Jaaro-Peled, S. Tankou et al., "Adolescent stressinduced epigenetic control of dopaminergic neurons via glucocorticoids, " Science, vol. 339, no. 6117, pp. 335-339, 2013.
    • (2013) Science , vol.339 , Issue.6117 , pp. 335-339
    • Niwa, M.1    Jaaro-Peled, H.2    Tankou, S.3
  • 156
    • 18444364206 scopus 로고    scopus 로고
    • Genetic variation in the 6p22. 3 Gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia
    • R. E. Straub, Y. Jiang, C. J. MacLean et al., "Genetic variation in the 6p22. 3 Gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia, " American Journal of Human Genetics, vol. 71, no. 2, pp. 337-348, 2002.
    • (2002) American Journal of Human Genetics , vol.71 , Issue.2 , pp. 337-348
    • Straub, R.E.1    Jiang, Y.2    MacLean, C.J.3
  • 157
    • 71649113424 scopus 로고    scopus 로고
    • The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample
    • B. Riley, P.-H. Kuo, B. S. Maher et al., "The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample, " Schizophrenia Research, vol. 115, no. 2-3, pp. 245-253, 2009.
    • (2009) Schizophrenia Research , vol.115 , Issue.2-3 , pp. 245-253
    • Riley, B.1    Kuo, P.-H.2    Maher, B.S.3
  • 158
    • 84866372949 scopus 로고    scopus 로고
    • Convergent functional genomics of schizophrenia: From comprehensive understanding to genetic risk prediction
    • M. Ayalew, H. Le-Niculescu, D. F. Levey et al., "Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction, "Molecular Psychiatry, vol. 17, no. 9, pp. 887-905, 2012.
    • (2012) Molecular Psychiatry , vol.17 , Issue.9 , pp. 887-905
    • Ayalew, M.1    Le-Niculescu, H.2    Levey, D.F.3
  • 159
    • 33845292885 scopus 로고    scopus 로고
    • DTNBP1 genotype influences cognitive decline in schizophrenia
    • K. E. Burdick, T. E. Goldberg, B. Funke et al., "DTNBP1 genotype influences cognitive decline in schizophrenia, " Schizophrenia Research, vol. 89, no. 1-3, pp. 169-172, 2007.
    • (2007) Schizophrenia Research , vol.89 , Issue.1-3 , pp. 169-172
    • Burdick, K.E.1    Goldberg, T.E.2    Funke, B.3
  • 160
    • 77954331106 scopus 로고    scopus 로고
    • DTNBP1 (dysbindin) gene variantsmodulate prefrontal brain function in schizophrenic patients-support for the glutamate hypothesis of schizophrenias
    • A. J. Fallgatter, A.-C. Ehlis, M. J. Herrmann et al., "DTNBP1 (dysbindin) gene variantsmodulate prefrontal brain function in schizophrenic patients-support for the glutamate hypothesis of schizophrenias, " Genes, Brain and Behavior, vol. 9, no. 5, pp. 489-497, 2010.
    • (2010) Genes, Brain and Behavior , vol.9 , Issue.5 , pp. 489-497
    • Fallgatter, A.J.1    Ehlis, A.-C.2    Herrmann, M.J.3
  • 161
    • 78649865999 scopus 로고    scopus 로고
    • Metaanalysis of genetic variation in DTNBP1 and general cognitive ability
    • J.-P. Zhang, K. E. Burdick, T. Lencz, and A. K. Malhotra, "Metaanalysis of genetic variation in DTNBP1 and general cognitive ability, " Biological Psychiatry, vol. 68, no. 12, pp. 1126-1133, 2010.
    • (2010) Biological Psychiatry , vol.68 , Issue.12 , pp. 1126-1133
    • Zhang, J.-P.1    Burdick, K.E.2    Lencz, T.3    Malhotra, A.K.4
  • 162
    • 37049006760 scopus 로고    scopus 로고
    • Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients
    • C. S. Weickert, D. A. Rothmond, T. M. Hyde, J. E. Kleinman, and R. E. Straub, "Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients, " Schizophrenia Research, vol. 98, no. 1-3, pp. 105-110, 2008.
    • (2008) Schizophrenia Research , vol.98 , Issue.1-3 , pp. 105-110
    • Weickert, C.S.1    Rothmond, D.A.2    Hyde, T.M.3    Kleinman, J.E.4    Straub, R.E.5
  • 163
    • 70349561789 scopus 로고    scopus 로고
    • Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression
    • J. Tang, R. P. LeGros, N. Louneva et al., "Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression, " HumanMolecular Genetics, vol. 18, no. 20, pp. 3851-3863, 2009.
    • (2009) HumanMolecular Genetics , vol.18 , Issue.20 , pp. 3851-3863
    • Tang, J.1    LeGros, R.P.2    Louneva, N.3
  • 164
    • 84940510235 scopus 로고    scopus 로고
    • The schizophrenia-related protein dysbindin-1A is degraded and facilitates NF-Kappa B activity in the nucleus
    • C. Fu, D. Chen, R. Chen, Q. Hu, G. Wang, and K.-L. Lim, "The schizophrenia-related protein dysbindin-1A is degraded and facilitates NF-Kappa B activity in the nucleus, " PLoS ONE, vol. 10, no. 7, Article ID e0132639, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.7
    • Fu, C.1    Chen, D.2    Chen, R.3    Hu, Q.4    Wang, G.5    Lim, K.-L.6
  • 166
    • 58149501704 scopus 로고    scopus 로고
    • Impaired longterm memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia
    • K. Takao, K. Toyama, K. Nakanishi et al., "Impaired longterm memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia, " Molecular brain, vol. 1, article 11, 2008.
    • (2008) Molecular Brain , vol.1
    • Takao, K.1    Toyama, K.2    Nakanishi, K.3
  • 167
    • 70350052966 scopus 로고    scopus 로고
    • Dysbindin modulates prefrontal cortical glutamatergic circuits andworkingmemory function in mice
    • J. D. Jentsch, H. Trantham-Davidson, C. Jairl, M. Tinsley, T. D. Cannon, and A. Lavin, "Dysbindin modulates prefrontal cortical glutamatergic circuits andworkingmemory function in mice, " Neuropsychopharmacology, vol. 34, no. 12, pp. 2601-2608, 2009.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.12 , pp. 2601-2608
    • Jentsch, J.D.1    Trantham-Davidson, H.2    Jairl, C.3    Tinsley, M.4    Cannon, T.D.5    Lavin, A.6
  • 168
    • 78650006680 scopus 로고    scopus 로고
    • Reduced dysbindin expression mediates N-methyl-D-aspartate receptor hypofunction and impaired working memory performance
    • K. H. Karlsgodt, K. Robleto, H. Trantham-Davidson et al., "Reduced dysbindin expression mediates N-methyl-D-aspartate receptor hypofunction and impaired working memory performance, " Biological Psychiatry, vol. 69, no. 1, pp. 28-34, 2011.
    • (2011) Biological Psychiatry , vol.69 , Issue.1 , pp. 28-34
    • Karlsgodt, K.H.1    Robleto, K.2    Trantham-Davidson, H.3
  • 169
    • 84855340012 scopus 로고    scopus 로고
    • Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine/D2 pathways
    • F. Papaleo, F. Yang, S. Garcia et al., "Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine/D2 pathways, "Molecular Psychiatry, vol. 17, no. 1, pp. 85-98, 2012.
    • (2012) Molecular Psychiatry , vol.17 , Issue.1 , pp. 85-98
    • Papaleo, F.1    Yang, F.2    Garcia, S.3
  • 170
    • 84892676724 scopus 로고    scopus 로고
    • Dysbindin-1 loss compromises NMDAR-dependent synaptic plasticity andcontextual fear conditioning
    • W. B. Glen Jr., B. Horowitz, G. C. Carlson et al., "Dysbindin-1 loss compromises NMDAR-dependent synaptic plasticity andcontextual fear conditioning, " Hippocampus, vol. 24, no. 2, pp. 204-213, 2014.
    • (2014) Hippocampus , vol.24 , Issue.2 , pp. 204-213
    • Glen, W.B.1    Horowitz, B.2    Carlson, G.C.3
  • 171
    • 84939534135 scopus 로고    scopus 로고
    • Loss of dysbindin-1, a risk gene for schizophrenia, leads to impaired group 1 metabotropic glutamate receptor function in mice
    • S. K. Bhardwaj, R. T. Ryan, T. P. Wong, and L. K. Srivastava, "Loss of dysbindin-1, a risk gene for schizophrenia, leads to impaired group 1 metabotropic glutamate receptor function in mice, " Frontiers in Behavioral Neuroscience, vol. 9, article 72, 2015.
    • (2015) Frontiers in Behavioral Neuroscience , vol.9
    • Bhardwaj, S.K.1    Ryan, R.T.2    Wong, T.P.3    Srivastava, L.K.4
  • 172
    • 78650009234 scopus 로고    scopus 로고
    • Dysbindin and Schizophrenia: It's dopamine and glutamate all over again
    • F. Papaleo and D. R. Weinberger, "Dysbindin and Schizophrenia: it's dopamine and glutamate all over again, " Biological Psychiatry, vol. 69, no. 1, pp. 2-4, 2011.
    • (2011) Biological Psychiatry , vol.69 , Issue.1 , pp. 2-4
    • Papaleo, F.1    Weinberger, D.R.2
  • 173
    • 67149095290 scopus 로고    scopus 로고
    • Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background
    • M. M. Cox, A. M. Tucker, J. Tang et al., "Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background, " Genes, Brain and Behavior, vol. 8, no. 4, pp. 390-397, 2009.
    • (2009) Genes, Brain and Behavior , vol.8 , Issue.4 , pp. 390-397
    • Cox, M.M.1    Tucker, A.M.2    Tang, J.3
  • 174
    • 45349094387 scopus 로고    scopus 로고
    • Serious obstetric complications interact with hypoxia-regulated/vascularexpression genes to influence schizophrenia risk
    • K. K. Nicodemus, S. Marenco, A. J. Batten et al., "Serious obstetric complications interact with hypoxia-regulated/vascularexpression genes to influence schizophrenia risk, " Molecular Psychiatry, vol. 13, no. 9, pp. 873-877, 2008.
    • (2008) Molecular Psychiatry , vol.13 , Issue.9 , pp. 873-877
    • Nicodemus, K.K.1    Marenco, S.2    Batten, A.J.3
  • 175
    • 77954324866 scopus 로고    scopus 로고
    • A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia
    • J. Voisey, C. D. Swagell, I. P. Hughes et al., "A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia, " Behavioral and Brain Functions, vol. 6, article 41, 2010.
    • (2010) Behavioral and Brain Functions , vol.6
    • Voisey, J.1    Swagell, C.D.2    Hughes, I.P.3
  • 176
    • 46049086735 scopus 로고    scopus 로고
    • Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia
    • S. Hattori, T. Murotani, S. Matsuzaki et al., "Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia, " Biochemical and Biophysical Research Communications, vol. 373, no. 2, pp. 298-302, 2008.
    • (2008) Biochemical and Biophysical Research Communications , vol.373 , Issue.2 , pp. 298-302
    • Hattori, S.1    Murotani, T.2    Matsuzaki, S.3
  • 177
    • 75549089372 scopus 로고    scopus 로고
    • The dysbindin-containing complex (BLOC-1) in brain: Developmental regulation, interaction with SNARE proteins and role in neurite outgrowth
    • C. A. Ghiani, M. Starcevic, I. A. Rodriguez-Fernandez et al., "The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth, " Molecular Psychiatry, vol. 15, no. 2, pp. 204-215, 2010.
    • (2010) Molecular Psychiatry , vol.15 , Issue.2 , pp. 204-215
    • Ghiani, C.A.1    Starcevic, M.2    Rodriguez-Fernandez, I.A.3
  • 178
    • 58849092285 scopus 로고    scopus 로고
    • Membrane fusion: Grappling with SNARE and SM proteins
    • T. C. Südhof and J. E. Rothman, "Membrane fusion: grappling with SNARE and SM proteins, " Science, vol. 323, no. 5913, pp. 474-477, 2009.
    • (2009) Science , vol.323 , Issue.5913 , pp. 474-477
    • Südhof, T.C.1    Rothman, J.E.2
  • 179
    • 0038003196 scopus 로고    scopus 로고
    • Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia
    • C. M. Lewis, D. F. Levinson, L. H. Wise et al., "Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: schizophrenia, " American Journal of Human Genetics, vol. 73, no. 1, pp. 34-48, 2003.
    • (2003) American Journal of Human Genetics , vol.73 , Issue.1 , pp. 34-48
    • Lewis, C.M.1    Levinson, D.F.2    Wise, L.H.3
  • 180
    • 84872600527 scopus 로고    scopus 로고
    • Preliminary evidence for association between schizophrenia and polymorphisms in the regulatory regions of the ADRA2A, DRD3 and SNAP-25 genes
    • J. Lochman, V. J. Balcar, F. St'astný, and O. Sery, "Preliminary evidence for association between schizophrenia and polymorphisms in the regulatory regions of the ADRA2A, DRD3 and SNAP-25 genes, " Psychiatry Research, vol. 205, no. 1-2, pp. 7-12, 2013.
    • (2013) Psychiatry Research , vol.205 , Issue.1-2 , pp. 7-12
    • Lochman, J.1    Balcar, V.J.2    St'Astný, F.3    Sery, O.4
  • 181
    • 33947264082 scopus 로고    scopus 로고
    • D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD
    • X. Fan and E. J. Hess, "D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD, " Neurobiology of Disease, vol. 26, no. 1, pp. 201-211, 2007.
    • (2007) Neurobiology of Disease , vol.26 , Issue.1 , pp. 201-211
    • Fan, X.1    Hess, E.J.2
  • 182
    • 70449532982 scopus 로고    scopus 로고
    • D2 dopamine receptor subtypemediated hyperactivity and amphetamine responses in amodel of ADHD
    • X. Fan, M. Xu, and E. J. Hess, "D2 dopamine receptor subtypemediated hyperactivity and amphetamine responses in amodel of ADHD, " Neurobiology of Disease, vol. 37, no. 1, pp. 228-236, 2010.
    • (2010) Neurobiology of Disease , vol.37 , Issue.1 , pp. 228-236
    • Fan, X.1    Xu, M.2    Hess, E.J.3
  • 183
    • 70449334191 scopus 로고    scopus 로고
    • Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk
    • P. L. Oliver and K. E. Davies, "Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk, " Human Molecular Genetics, vol. 18, no. 23, pp. 4576-4589, 2009.
    • (2009) Human Molecular Genetics , vol.18 , Issue.23 , pp. 4576-4589
    • Oliver, P.L.1    Davies, K.E.2
  • 184
    • 84883799213 scopus 로고    scopus 로고
    • Gene-environment interactions affect long-term depression (LTD) through changes in dopamine receptor affinity in Snap25 deficient mice
    • M. Baca, A. M. Allan, L. D. Partridge, and M. C. Wilson, "Gene-environment interactions affect long-term depression (LTD) through changes in dopamine receptor affinity in Snap25 deficient mice, " Brain Research, vol. 1532, pp. 85-98, 2013.
    • (2013) Brain Research , vol.1532 , pp. 85-98
    • Baca, M.1    Allan, A.M.2    Partridge, L.D.3    Wilson, M.C.4
  • 185
    • 84893780369 scopus 로고    scopus 로고
    • A positive correlation between serum levels of mature brain-derived neurotrophic factor and negative symptoms in schizophrenia
    • T. Niitsu, T. Ishima, T. Yoshida et al., "A positive correlation between serum levels of mature brain-derived neurotrophic factor and negative symptoms in schizophrenia, " Psychiatry Research, vol. 215, no. 2, pp. 268-273, 2014.
    • (2014) Psychiatry Research , vol.215 , Issue.2 , pp. 268-273
    • Niitsu, T.1    Ishima, T.2    Yoshida, T.3
  • 186
    • 84907997380 scopus 로고    scopus 로고
    • Brain derived neurotropic factor (BDNF) is associated with childhood abuse but not cognitive domains in first episode psychosis
    • C. Theleritis, H. L. Fisher, I. Shäfer et al., "Brain derived neurotropic factor (BDNF) is associated with childhood abuse but not cognitive domains in first episode psychosis, " Schizophrenia Research, vol. 159, no. 1, pp. 56-61, 2014.
    • (2014) Schizophrenia Research , vol.159 , Issue.1 , pp. 56-61
    • Theleritis, C.1    Fisher, H.L.2    Shäfer, I.3
  • 187
    • 84994878601 scopus 로고    scopus 로고
    • Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: Relevance for the study of chromatin remodeling properties of antipsychotic drugs
    • E. Dong, P. Tueting, F. Matrisciano, D. R. Grayson, and A. Guidotti, "Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs, " Translational Psychiatry, vol. 6, article e711, 2016.
    • (2016) Translational Psychiatry , vol.6
    • Dong, E.1    Tueting, P.2    Matrisciano, F.3    Grayson, D.R.4    Guidotti, A.5
  • 189
    • 84878431731 scopus 로고    scopus 로고
    • BDNF deficiency and young-adult methamphetamine induce sex-specific effects on prepulse inhibition regulation
    • E. E. Manning and M. van den Buuse, "BDNF deficiency and young-adult methamphetamine induce sex-specific effects on prepulse inhibition regulation, " Frontiers in Cellular Neuroscience, vol. 7, article 92, 2013.
    • (2013) Frontiers in Cellular Neuroscience , vol.7
    • Manning, E.E.1    Buuse Den Van, M.2
  • 190
    • 0033646608 scopus 로고    scopus 로고
    • Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression
    • S. H. Fatemi, J. A. Earle, and T. McMenomy, "Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression, " Molecular Psychiatry, vol. 5, no. 6, pp. 654-663, 2000.
    • (2000) Molecular Psychiatry , vol.5 , Issue.6 , pp. 654-663
    • Fatemi, S.H.1    Earle, J.A.2    McMenomy, T.3
  • 191
    • 77954203843 scopus 로고    scopus 로고
    • Reelin-mediated signaling in neuropsychiatric and neurodegenerative diseases
    • I. Knuesel, "Reelin-mediated signaling in neuropsychiatric and neurodegenerative diseases, " Progress in Neurobiology, vol. 91, no. 4, pp. 257-274, 2010.
    • (2010) Progress in Neurobiology , vol.91 , Issue.4 , pp. 257-274
    • Knuesel, I.1
  • 192
    • 61849135475 scopus 로고    scopus 로고
    • Gene-environment interaction during early development in the heterozygous reeler mouse: Clues for modelling of major neurobehavioral syndromes
    • G. Laviola, E. Ognibene, E. Romano, W. Adriani, and F. Keller, "Gene-environment interaction during early development in the heterozygous reeler mouse: clues for modelling of major neurobehavioral syndromes, " Neuroscience and Biobehavioral Reviews, vol. 33, no. 4, pp. 560-572, 2009.
    • (2009) Neuroscience and Biobehavioral Reviews , vol.33 , Issue.4 , pp. 560-572
    • Laviola, G.1    Ognibene, E.2    Romano, E.3    Adriani, W.4    Keller, F.5
  • 193
    • 33846001701 scopus 로고    scopus 로고
    • Neurobehavioural disorders in the infant reeler mouse model: Interaction of genetic vulnerability and consequences of maternal separation
    • E. Ognibene, W. Adriani, S. Macr, and G. Laviola, "Neurobehavioural disorders in the infant reeler mouse model: interaction of genetic vulnerability and consequences of maternal separation, " Behavioural Brain Research, vol. 177, no. 1, pp. 142-149, 2007.
    • (2007) Behavioural Brain Research , vol.177 , Issue.1 , pp. 142-149
    • Ognibene, E.1    Adriani, W.2    Macr, S.3    Laviola, G.4
  • 194
    • 84905037077 scopus 로고    scopus 로고
    • Effects of prenatal hypoxia on schizophrenia-related phenotypes in heterozygous reeler mice: A gene ™ environment interaction study
    • K. R. Howell and A. Pillai, "Effects of prenatal hypoxia on schizophrenia-related phenotypes in heterozygous reeler mice: A gene ™ environment interaction study, " European Neuropsychopharmacology, vol. 24, no. 8, pp. 1324-1336, 2014.
    • (2014) European Neuropsychopharmacology , vol.24 , Issue.8 , pp. 1324-1336
    • Howell, K.R.1    Pillai, A.2
  • 195
    • 69249229726 scopus 로고    scopus 로고
    • Animal models of gene-environment interactions in schizophrenia
    • Y. Ayhan, A. Sawa, C. A. Ross, and M. V. Pletnikov, "Animal models of gene-environment interactions in schizophrenia, " Behavioural Brain Research, vol. 204, no. 2, pp. 274-281, 2009.
    • (2009) Behavioural Brain Research , vol.204 , Issue.2 , pp. 274-281
    • Ayhan, Y.1    Sawa, A.2    Ross, C.A.3    Pletnikov, M.V.4
  • 196
    • 79960470756 scopus 로고    scopus 로고
    • Geneenvironment interactions and construct validity in preclinical models of psychiatric disorders
    • E. L. Burrows, C. E. McOmish, and A. J. Hannan, "Geneenvironment interactions and construct validity in preclinical models of psychiatric disorders, " Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 35, no. 6, pp. 1376-1382, 2011.
    • (2011) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.35 , Issue.6 , pp. 1376-1382
    • Burrows, E.L.1    McOmish, C.E.2    Hannan, A.J.3
  • 197
    • 19144373244 scopus 로고    scopus 로고
    • Behavioural sensitization to daily life stress in psychosis
    • I. Myin-Germeys, P. Delespaul, and J. van Os, "Behavioural sensitization to daily life stress in psychosis, " Psychological Medicine, vol. 35, no. 5, pp. 733-741, 2005.
    • (2005) Psychological Medicine , vol.35 , Issue.5 , pp. 733-741
    • Myin-Germeys, I.1    Delespaul, P.2    Van Os, J.3
  • 199
  • 200
    • 0031661035 scopus 로고    scopus 로고
    • Are there sex differences in neuropsychological functions among patientswith schizophrenia
    • J. M. Goldstein, L. J. Seidman, J. M. Goodman et al., "Are there sex differences in neuropsychological functions among patientswith schizophrenia" American Journal of Psychiatry, vol. 155, no. 10, pp. 1358-1364, 1998.
    • (1998) American Journal of Psychiatry , vol.155 , Issue.10 , pp. 1358-1364
    • Goldstein, J.M.1    Seidman, L.J.2    Goodman, J.M.3
  • 202
    • 84855307242 scopus 로고    scopus 로고
    • Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia
    • D. A. Lewis, A. A. Curley, J. R. Glausier, and D. W. Volk, "Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia, " Trends in Neurosciences, vol. 35, no. 1, pp. 57-67, 2012.
    • (2012) Trends in Neurosciences , vol.35 , Issue.1 , pp. 57-67
    • Lewis, D.A.1    Curley, A.A.2    Glausier, J.R.3    Volk, D.W.4
  • 203
    • 84975473447 scopus 로고    scopus 로고
    • Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons
    • S. Canetta, S. Bolkan, N. Padilla-Coreano et al., "Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons, "Molecular Psychiatry, vol. 21, no. 7, pp. 956-968, 2016.
    • (2016) Molecular Psychiatry , vol.21 , Issue.7 , pp. 956-968
    • Canetta, S.1    Bolkan, S.2    Padilla-Coreano, N.3
  • 204
    • 68949180394 scopus 로고    scopus 로고
    • Schizophrenia
    • J. vanOs and S. Kapur, "Schizophrenia, " The Lancet, vol. 374, no. 9690, pp. 635-645, 2009.
    • (2009) The Lancet , vol.374 , Issue.9690 , pp. 635-645
    • VanOs, J.1    Kapur, S.2
  • 205
    • 84941656023 scopus 로고    scopus 로고
    • Bridging the gap between research into biological and psychosocial models of psychosis
    • R. M. Murray, L. Sideli, C. La Cascia, andD. La Barbera, "Bridging the gap between research into biological and psychosocial models of psychosis, " Shanghai Archives of Psychiatry, vol. 27, no. 3, pp. 139-143, 2015.
    • (2015) Shanghai Archives of Psychiatry , vol.27 , Issue.3 , pp. 139-143
    • Murray, R.M.1    Sideli, L.2    La Cascia, C.3    La Barbera, D.4
  • 207
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • P. J. Harrison and D. R. Weinberger, "Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence, " Molecular Psychiatry, vol. 10, no. 1, pp. 40-68, 2005.
    • (2005) Molecular Psychiatry , vol.10 , Issue.1 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2


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