Meta-analysis of genetic variation in DTNBP1 and general cognitive ability

Biological Psychiatry

Volumn 68, Issue 12, 2010, Pages 1126-1133

  Zhang, Jian Ping ^a   Burdick, Katherine E ^a,b,c   Lencz, Todd ^a,b,c,d   Malhotra, Anil K ^a,b,c  

^a ZUCKER HILLSIDE HOSPITAL   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

Author keywords

DTNBP1; general cognitive ability; genetics; healthy control; human; meta analysis

Indexed keywords

DYSBINDIN;

ALLELE; ARTICLE; CLINICAL TRIAL; COGNITION; COHORT ANALYSIS; CORRELATION COEFFICIENT; GENETIC VARIABILITY; HOMOZYGOTE; HUMAN; MEDLINE; META ANALYSIS; NEUROPSYCHOLOGICAL TEST; PHENOTYPE; PRIORITY JOURNAL; PUBLISHING; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW;

CARRIER PROTEINS; COGNITION; HUMANS; META-ANALYSIS AS TOPIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 78649865999     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.09.016     Document Type: Article

References (51)

1. A.Y. Guo, J. Sun, B.P. Riley, D.L. Thiselton, K.S. Kendler, and Z. Zhao The dystrobrevin-binding protein 1 gene: Features and networks Mol Psychiatry 14 2009 18 29
2. C.S. Weickert, R.E. Straub, B.W. McClintock, M. Matsumoto, R. Hashimoto, and T.M. Hyde Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain Arch Gen Psychiatry 61 2004 544 555
3. K. Talbot, D.S. Cho, W.Y. Ong, M.A. Benson, L.Y. Han, and H.A. Kazi Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin Hum Mol Genet 15 2006 3041 3054
4. D.K. Dickman, and G.W. Davis The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis Science 326 2009 1127 1130
5. X.W. Chen, Y.Q. Feng, C.J. Hao, X.L. Guo, X. He, and Z.Y. Zhou DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release J Cell Biol 181 2008 791 801
6. K. Kubota, N. Kumamoto, S. Matsuzaki, R. Hashimoto, T. Hattori, and H. Okuda Dysbindin engages in c-Jun N-terminal kinase activity and cytoskeletal organization Biochem Biophys Res Commun 379 2009 191 195
7. C.A. Ghiani, M. Starcevic, I.A. Rodriguez-Fernandez, R. Nazarian, V.T. Cheli, and L.N. Chan The dysbindin-containing complex (BLOC-1) in brain: Developmental regulation, interaction with SNARE proteins and role in neurite outgrowth Mol Psychiatry 115 2009 204 215
8. R.E. Straub, Y. Jiang, C.J. MacLean, Y. Ma, B.T. Webb, and M.V. Myakishev Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia Am J Hum Genet 71 2002 337 348
9. B. Funke, C.T. Finn, A.M. Plocik, S. Lake, P. DeRosse, and J.M. Kane Association of the DTNBP1 locus with schizophrenia in a U.S. population Am J Hum Genet 75 2004 891 898
10. D. Li, and L. He Association study between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia: A meta-analysis Schizophr Res 96 2007 112 118
11. N.C. Allen, S. Bagade, M.B. McQueen, J.P. Ioannidis, F.K. Kavvoura, and M.J. Khoury Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database Nat Genet 40 2008 827 834
12. K.E. Burdick, T. Lencz, B. Funke, C.T. Finn, P.R. Szeszko, and J.M. Kane Genetic variation in DTNBP1 influences general cognitive ability Hum Mol Genet 15 2006 1563 1568
13. K.E. Burdick, T.E. Goldberg, B. Funke, J.A. Bates, T. Lencz, and R. Kucherlapati DTNBP1 genotype influences cognitive decline in schizophrenia Schizophr Res 89 2007 169 172
14. N.C. Stefanis, T.A. Trikalinos, D. Avramopoulos, N. Smyrnis, I. Evdokimidis, and E.E. Ntzani Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level Biol Psychiatry 62 2007 784 792
15. G. Donohoe, D.W. Morris, S. Clarke, K.A. McGhee, S. Schwaiger, and J.M. Nangle Variance in neurocognitive performance is associated with dysbindin-1 in schizophrenia: A preliminary study Neuropsychologia 45 2007 454 458 (Pubitemid 44828767)
16. J.R. Zinkstok, O. de Wilde, T.A. van Amelsvoort, M.W. Tanck, F. Baas, and D.H. Linszen Association between the DTNBP1 gene and intelligence: A case-control study in young patients with schizophrenia and related disorders and unaffected siblings Behav Brain Funct 3 2007 19
17. M. Luciano, F. Miyajima, P.A. Lind, T.C. Bates, M. Horan, and S.E. Harris Variation in the dysbindin gene and normal cognitive function in three independent population samples Genes Brain Behav 8 2009 218 227
18. T. Kircher, V. Markov, A. Krug, T. Eggermann, K. Zerres, and M.M. Nothen Association of the DTNBP1 genotype with cognition and personality traits in healthy subjects Psychol Med 39 2009 1657 1665
19. R. Hashimoto, H. Noguchi, H. Hori, K. Ohi, Y. Yasuda, M. Takeda, and H. Kunugi Association between the dysbindin gene (DTNBP1) and cognitive functions in Japanese subjects Psychiatry Clin Neurosci 63 2009 550 556
20. A.C. Need, D.K. Attix, J.M. McEvoy, E.T. Cirulli, K.L. Linney, and P. Hunt A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB Hum Mol Genet 18 2009 4650 4661
21. M.R. Munafo, and J. Flint Meta-analysis of genetic association studies Trends Genet 20 2004 439 444
22. C. Spearman General intelligence, objectively determined and measured Am J Psychol 15 1904 201 292
23. R. Plomin, and F.M. Spinath Intelligence: Genetics, genes, and genomics J Pers Soc Psychol 86 2004 112 129
24. R. Plomin Genetics and general cognitive ability Nature 402 6761 suppl 1999 C25 C29
25. J.H. Barnett, L. Scoriels, and M.R. Munafo Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism Biol Psychiatry 64 2008 137 144
26. R. Hashimoto, H. Noguchi, H. Hori, T. Nakabayashi, T. Suzuki, and N. Iwata A genetic variation in the dysbindin gene (DTNBP1) is associated with memory performance in healthy controls World J Biol Psychiatry 11 2009 431 438
27. I.J. Deary Human intelligence differences: Towards a combined experimental-differential approach Trends Cogn Sci 5 2001 164 170
28. M. Borenstein, L.V. Hedges, J.P.T. Higgins, and H.R. Rothstein Introduction to Meta-Analysis 2009 John Wiley & Sons, Ltd Chichester, West Sussex, UK
29. J.P. Higgins, S.G. Thompson, J.J. Deeks, and D.G. Altman Measuring inconsistency in meta-analyses BMJ 327 2003 557 560
30. M. Egger, G.D. Smith, M. Schneider, and C. Minder Bias in meta-analysis detected by a simple, graphical test BMJ 315 1997 629 634
31. S.J. Duval, and R.L. Tweedie A non-parametric "trim and fill" method of assessing publication bias in meta-analysis J Am Stat Assoc 95 2000 89 98
32. P. Kraft Curseswinner's and otherwisein genetic epidemiology Epidemiology 19 2008 649 651 discussion:657658
33. U.M. O'Leary, K.M. Rusch, and S.J. Guastello Estimating age-stratified WAIS-R IQS from scores on the Raven's Standard Progressive Matrices J Clin Psychol 47 1991 277 284
34. S. Lehrl, G. Triebig, and B. Fischer Multiple choice vocabulary test MWT as a valid and short test to estimate premorbid intelligence Acta Neurol Scand 91 1995 335 345
35. W. Li, Q. Zhang, N. Oiso, E.K. Novak, R. Gautam, and E.P. O'Brien Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1) Nat Genet 35 2003 84 89
36. K. Talbot, W.Y. Ong, D.J. Blake, J. Tang, N. Louneva, and G.C. Carlson Dysbindin-1 and its protein family D. Javitt, J. Kantrowitz, Handbook of Neurochemistry and Molecular Neurobiology: Schizophrenia 2009 Springer Publishers New York 110 241
37. A.J. Fallgatter, M.J. Herrmann, C. Hohoff, A.C. Ehlis, T.A. Jarczok, C.M. Freitag, and J. Deckert DTNBP1 (dysbindin) gene variants modulate prefrontal brain function in healthy individuals Neuropsychopharmacology 31 2006 2002 2010
38. V. Markov, A. Krug, S. Krach, C. Whitney, T. Eggermann, and K. Zerres Genetic variation in schizophrenia-risk-gene dysbindin 1 modulates brain activation in anterior cingulate cortex and right temporal gyrus during language production in healthy individuals Neuroimage 47 2009 2016 2022
39. K.L. Narr, P.R. Szeszko, T. Lencz, R.P. Woods, L.S. Hamilton, and O. Phillips DTNBP1 is associated with imaging phenotypes in schizophrenia Hum Brain Mapp 30 2009 3783 3794
40. V. Markov, A. Krug, S. Krach, A. Jansen, T. Eggermann, and K. Zerres Impact of schizophrenia-risk gene dysbindin 1 on brain activation in bilateral middle frontal gyrus during a working memory task in healthy individuals Hum Brain Mapp 31 2010 266 275
41. M. Thimm, A. Krug, V. Markov, S. Krach, A. Jansen, and K. Zerres The impact of dystrobrevin-binding protein 1 (DTNBP1) on neural correlates of episodic memory encoding and retrieval Hum Brain Mapp 31 2010 203 209
42. M.A. Benson, S.E. Newey, E. Martin-Rendon, R. Hawkes, and D.J. Blake Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain J Biol Chem 276 2001 24232 24241
43. M. Ceccarini, M. Grasso, C. Veroni, G. Gambara, B. Artegiani, and G. Macchia Association of dystrobrevin and regulatory subunit of protein kinase A: A new role for dystrobrevin as a scaffold for signaling proteins J Mol Biol 371 2007 1174 1187
44. T.T. Tang, F. Yang, B.S. Chen, Y. Lu, Y. Ji, K.W. Roche, and B. Lu Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression Proc Natl Acad Sci U S A 106 2009 21395 21400
45. Y. Iizuka, Y. Sei, D.R. Weinberger, and R.E. Straub Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization J Neurosci 27 2007 12390 12395
46. Y. Ji, F. Yang, F. Papaleo, H.X. Wang, W.J. Gao, D.R. Weinberger, and B. Lu Role of dysbindin in dopamine receptor trafficking and cortical GABA function Proc Natl Acad Sci U S A 106 2009 19593 19598
47. P.M. Wall, and C. Messier The hippocampal formationorbitomedial prefrontal cortex circuit in the attentional control of active memory Behav Brain Res 127 2001 99 117
48. R. Plomin, M.J. Owen, and P. McGuffin The genetic basis of complex human behaviors Science 264 1994 1733 1739
49. N. Soranzo, F. Rivadeneira, U. Chinappen-Horsley, I. Malkina, J.B. Richards, and N. Hammond Meta-analysis of genome-wide scans for human adult stature identifies novel loci and associations with measures of skeletal frame size PLoS Genet 5 2009 e1000445
50. G. Lettre Genetic regulation of adult stature Curr Opin Pediatr 21 2009 515 522
51. K. Peters, S. Wiltshire, A.K. Henders, M. Dragovic, J.C. Badcock, and D. Chandler Comprehensive analysis of tagging sequence variants in DTNBP1 shows no association with schizophrenia or with its composite neurocognitive endophenotypes Am J Med Genet B Neuropsychiatr Genet 147B 2008 1159 1166