Association of Systolic Blood Pressure Variability With Mortality, Coronary Heart Disease, Stroke, and Renal Disease

Journal of the American College of Cardiology

Volumn 68, Issue 13, 2016, Pages 1375-1386

  Gosmanova, Elvira O ^a,b   Mikkelsen, Margit K ^c   Molnar, Miklos Z ^d   Lu, Jun L ^d   Yessayan, Lenar T ^e   Kalantar Zadeh, Kamyar ^f   Kovesdy, Csaba P ^d,g  

^a STRATTON VA MEDICAL CENTER   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

hypertension; outcomes; visit to visit variability

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOOP DIURETIC AGENT; POTASSIUM SPARING DIURETIC AGENT; THIAZIDE DIURETIC AGENT; VASODILATOR AGENT;

ADULT; AGE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE VARIABILITY; BODY MASS; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DEMOGRAPHY; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; END STAGE RENAL DISEASE; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MARRIAGE; MORTALITY; OUTPATIENT; PRIORITY JOURNAL; RACE DIFFERENCE; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; VETERAN; BLOOD PRESSURE; CHRONIC KIDNEY FAILURE; COMPLICATION; CORONARY ARTERY DISEASE; MIDDLE AGED; PATHOPHYSIOLOGY; UNITED STATES; VETERANS HEALTH;

BLOOD PRESSURE; COHORT STUDIES; CORONARY ARTERY DISEASE; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; RENAL INSUFFICIENCY, CHRONIC; STROKE; UNITED STATES; VETERANS HEALTH;

EID: 84990892327     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2016.06.054     Document Type: Article

References (44)

1. 1 Mozaffarian, D., Benjamin, E.J., Go, A.S., et al. Heart disease and stroke statistics–2016 update: a report from the American Heart Association. Circulation 133 (2016), e38–e360.
2. 2 James, P.A., Oparil, S., Carter, B.L., et al. 2014 evidence-based guidelines for the management of high blood pressure in adults. JAMA 311 (2014), 507–520.
3. 3 Collins, R., Peto, R., MacMahon, S., et al. Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 335 (1990), 827–838.
4. 4 Perry, H.M. Jr., Miller, J.P., Fornoff, J.R., et al. Early predictors of 15-year end-stage renal disease in hypertensive patients. Hypertension 25 (1995), 587–594.
5. 5 Stokes, J. 3rd, Kannel, W.B., Wolf, P.A., D'Agostino, R.B., Cupples, L.A., Blood pressure as a risk factor for cardiovascular disease. The Framingham Study–30 years of follow-up. Hypertension 13 (1989), I13–I18.
6. 6 Kovesdy, C.P., Bleyer, A.J., Molnar, M.Z., et al. Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study. Ann Intern Med 159 (2013), 233–242.
7. 7 Gosmanov, A.R., Lu, J.L., Sumida, K., et al. Synergistic association of combined glycemic and blood pressure level with risk of complications in US veterans with diabetes. J Hypertens 34 (2016), 907–913.
8. 8 Kovesdy, C.P., Alrifai, A.A.Z., Gosmanova, E.O., et al. Age and outcomes associated with blood pressure in patients with incident CKD. Clin J Am Soc Nephrol 11 (2016), 821–831.
9. 9 Parati, G., Ochoa, J.E., Salvi, P., Lombardi, C., Bilo, G., Prognostic value of blood pressure variability and average blood pressure levels in patients with hypertension and diabetes. Hypertension 36 (2013), 312–323.
10. 10 Howard, S.C., Rothwell, P.M., Reproducibility of measures of visit-to-visit variability in blood pressure after transient ischaemic attack or minor stroke. Cerebrovasc Dis 28 (2009), 331–340.
11. 11 Muntner, P., Joyce, C., Levitan, E., et al. Reproducibility of visit-to-visit variability of blood pressure measured as part of routine clinical care. J Hypertens 29 (2011), 2332–2338.
12. 12 Clarke, R., Shipley, M., Lewington, S., et al. Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies. Am J Epidemiol 150 (1999), 341–353.
13. 13 Lewington, S., Clarke, R., Qizilbash, N., Peto, R., Collins, R., Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360 (2002), 1903–1913.
14. 14 Muntner, P., Shimbo, D., Tonelli, M., Reynolds, K., Arnett, D.K., Oparil, S., The relationship between visit-to-visit variability in systolic blood pressure and all-cause mortality in the general population. Hypertension 57 (2011), 160–166.
15. 15 McMullan, C.J., Bakris, G.L., Phillips, R.A., Forman, J.P., Association of BP variability with mortality among African Americans with CKD. Clin J Am Soc Nephrol 8 (2013), 731–738.
16. 16 Selvarajah, V., Pasea, L., Ojha, S., Wilkinson, I.B., Tomlinson, L.A., Pre-dialysis systolic blood pressure-variability is independently associated with all-cause mortality in incident haemodialysis patients. Plos One, 9, 2014, e86514.
17. 17 Rothwell, P.M., Howard, S.C., Dolan, E., et al. Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension. Lancet 375 (2010), 895–905.
18. 18 Shimbo, D., Newman, J., Aragaki, A., et al. Association between annual visit-to-visit blood pressure variability and stroke in postmenopausal women: Data from the Women's Health Initiative. Hypertension 60 (2012), 625–630.
19. 19 Okada, H., Fukui, M., Tanaka, M., et al. Visit-to-visit variability in systolic blood pressure is correlated with diabetic nephropathy and atherosclerosis in patients with type 2 diabetes. Atherosclerosis 220 (2012), 155–159.
20. 20 Poortvliet, R.K., Ford, I., Lloyd, S.M., et al. Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). Plos One, 7, 2012, e52438.
21. 21 Mancia, G., Facchetti, R., Parati, G., Zanchetti, A., Visit-to-visit blood pressure variability, carotid atherosclerosis, and cardiovascular events in the european lacidipine study on atherosclerosis. Circulation 126 (2012), 569–578.
22. 22 Schutte, R., Thijs, L., Liu, Y.-P., et al. Within-subject blood pressure level - not variability - predicts fatal and nonfatal outcomes in a general population. Hypertension 60 (2012), 1138–1147.
23. 23 Kovesdy, C.P., Norris, K.C., Boulware, L.E., et al. Association of race with mortality and cardiovascular events in a large cohort of US veterans. Circulation 132 (2015), 1538–1548.
24. 24 Lu, J.L., Molnar, M.Z., Naseer, A., Mikkelsen, M.K., Kalantar-Zadeh, K., Kovesdy, C.P., Association of age and BMI with kidney function and mortality: a cohort study. Lancet Diabetes Endocrinol 3 (2015), 704–714.
25. 25 Molnar, M.Z., Alhourani, H.M., Wall, B.M., et al. Association of hepatitis C viral infection with incidence and progression of chronic kidney disease in a large cohort of US veterans. Hepatology 61 (2015), 1495–1502.
26. 26 George, L.K., Molnar, M.Z., Lu, J.L., Kalantar-Zadeh, K., Koshy, S.K., Kovesdy, C.P., Association of pre-operative albuminuria with post-operative outcomes after coronary artery bypass grafting. Sci Rep, 5, 2015, 16458.
27. 27 Grams, M.E., Sang, Y., Coresh, J., et al. Acute kidney injury after major surgery: a retrospective analysis of Veterans Health Administration data. Am J Kidney Dis 67 (2016), 872–880.
28. 28 Molnar, M.Z., Mucsi, I., Novak, M., et al. Association of incident obstructive sleep apnoea with outcomes in a large cohort of US veterans. Thorax 70 (2015), 888–895.
29. 29 Stroupe, K.T., Tarlov, E., Zhang, Q., et al. Use of Medicare and DOD data for improving VA race data quality. J Rehabil Research Develop 47 (2010), 781–795.
30. 30 Sohn, M.W., Zhang, H., Arnold, N., et al. Transition to the new race/ethnicity data collection standards in the Department of Veterans Affairs. Popul Health Metr, 4, 2006, 7.
31. 31 Hajjar, I., Kotchen, T., Regional variations of blood pressure in the United States are associated with regional variations in dietary intakes: the NHANES-III data. J Nutr 133 (2003), 211–214.
32. 32 Smith, M.W., Joseph, G.J., Pharmacy data in the VA health care system. Med Care Res Rev 60 (2003), 92S–123S.
33. 33 Sohn, M.W., Arnold, N., Maynard, C., Hynes, D.M., Accuracy and completeness of mortality data in the Department of Veterans Affairs. Popul Health Metr, 4, 2006, 2.
34. 34 Gosmanova, E.O., Lu, J.L., Streja, E., et al. Association of medical treatment nonadherence with all-cause mortality in newly treated hypertensive US veterans. Hypertension 64 (2014), 951–957.
35. 35 Gosmanova, E.O., Molnar, M.Z., Alrifai, A., et al. Impact of non-adherence on renal and cardiovascular outcomes in US Veterans. Am J Nephrol 42 (2015), 151–157.
36. 36 Hata, J., Arima, H., Rothwell, P.M., et al. Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus. Circulation 128 (2013), 1325–1334.
37. 37 Yano, Y., Fujimoto, S., Kramer, H., et al. Long-term blood pressure variability, new-onset diabetes mellitus, and new-onset chronic kidney disease in the Japanese general population. Hypertension 66 (2015), 30–36.
38. 38 McMullan, C.J., Lambers Heerspink, H.J., Parving, H.H., Dwyer, J.P., Forman, J.P., de Zeeuw, D., Visit-to-visit variability in blood pressure and kidney and cardiovascular outcomes in patients with type 2 diabetes and nephropathy: a post hoc analysis from the RENAAL study and the Irbesartan Diabetic Nephropathy Trial. Am J Kidney Dis 64 (2014), 714–722.
39. 39 Whittle, J., Lunch, A.I., Tanner, R.M., et al. Visit-to-visit variability of BP and CKD outcomes: results of the ALLHAT. Clin J Am Soc Nephrol 11 (2016), 471–480.
40. 40 Muntner, P., Levitan, E.B., Joyce, C., et al. Association between antihypertensive medication adherence and visit-to-visit variability of blood pressure. J Clin Hypertens (Greenwich) 15 (2013), 112–117.
41. 41 Shimbo, D., Shea, S., McClelland, R.L., et al. Associations of aortic distensibility and arterial elasticity with long-term visit-to-visit blood pressure variability: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Hypertens 26 (2013), 896–902.
42. 42 Eguchi, K., Hoshide, S., Schwartz, J.E., et al. Visit-to-visit and ambulatory blood pressure variability as predictors of incident cardiovascular events in patients with hypertension. J Hypertens 30 (2012), 1556–1563.
43. 43 Eto, M., Toba, K., Akishita, M., et al. Reduced endothelial vasomotor function and enhanced neointimal formation after vascular injury in a rat model of blood pressure lability. Hypertens Res 26 (2003), 991–998.
44. 44 Webb, A.J., Fischer, U., Mehta, Z., Rothwell, P.M., Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis. Lancet 375 (2010), 906–915.