Within-subject blood pressure level-not variability-predicts fatal and nonfatal outcomes in a general population

Hypertension

Volumn 60, Issue 5, 2012, Pages 1138-1147

  Schutte, Rudolph ^a,b   Thijs, Lutgarde ^a   Liu, Yan Ping ^a   Asayama, Kei ^a,c   Jin, Yu ^a   Odili, Augustine ^a,d   Gu, Yu Mei ^a   Kuznetsova, Tatiana ^a   Jacobs, Lotte ^a   Staessen, Jan A ^a,e  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b NORTH WEST UNIVERSITY   (South Africa)

^c TOHOKU UNIVERSITY   (Japan)

^d UNIVERSITY OF ABUJA   (Nigeria)

^e MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

blood pressure variability; cardiovascular disease; epidemiology; population science; risk factors

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ADULT; ARTICLE; BLOOD PRESSURE VARIABILITY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; DEATH; FEMALE; FOLLOW UP; HAZARD RATIO; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; OUTCOME ASSESSMENT; PERIPHERAL ISCHEMIA; POPULATION; PRIORITY JOURNAL; PROGNOSIS; SYSTOLIC BLOOD PRESSURE;

ADRENERGIC BETA-ANTAGONISTS; ADULT; BELGIUM; BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; CARDIOVASCULAR DISEASES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT (HEALTH CARE); PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; YOUNG ADULT;

EID: 84868200843     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.202143     Document Type: Article

References (56)

1. Parati G, Pomidossi G, Albini F, Malaspina D, Mancia G. Relationship of 24-hour blood pressure mean and variability to severity of target-organ damage in hypertension. J Hypertens. 1987;5:93-98.
2. Tatasciore A, Renda G, Zimarino M, Soccio M, Bilo G, Parati G, Schillaci G, De Caterina R. Awake systolic blood pressure variability correlates with target-organ damage in hypertensive subjects. Hypertension. 2007;50:325-332.
3. Kawai T, Ohishi M, Kamide K, Onishi M, Takeya Y, Tatara Y, Oguro R, Yamamoto K, Sugimoto K, Rakugi H. The impact of visit-to-visit variability in blood pressure on renal function. Hypertens Res. 2012;35:239-243.
4. Matsui Y, Ishikawa J, Eguchi K, Shibasaki S, Shimada K, Kario K. Maximum value of home blood pressure: a novel indicator of target organ damage in hypertension. Hypertension. 2011;57:1087-1093.
5. Kikuya M, Hozawa A, Ohokubo T, Tsuji I, Michimata M, Matsubara M, Ota M, Nagai K, Araki T, Satoh H, Ito S, Hisamichi S, Imai Y. Prognostic significance of blood pressure and heart rate variabilities: the Ohasama study. Hypertension. 2000;36:901-906.
6. Johansson JK, Niiranen TJ, Puukka PJ, Jula AM. Prognostic value of the variability in home-measured blood pressure and heart rate: the Finn-Home Study. Hypertension. 2012;59:212-218.
7. Shimbo D, Newman JD, Aragaki AK, Lamonte MJ, Bavry AA, Allison M, Manson JE, Wassertheil-Smoller S. Association between annual visit-to-visit blood pressure variability and stroke in postmenopausal women: data from the women's health initiative. Hypertension. 2012;60:625-630.
8. Muntner P, Shimbo D, Tonelli M, Reynolds K, Arnett DK, Oparil S. The relationship between visit-to-visit variability in systolic blood pressure and all-cause mortality in the general population: findings from NHANES III, 1988 to 1994. Hypertension. 2011;57:160-166.
9. Schutte AE, Schutte R, Huisman HW, van Rooyen JM, Fourie CM, Malan NT, Malan L. Blood pressure variability is significantly associated with ECG left ventricular mass in normotensive Africans: the SABPA Study. Hypertens Res. 2011;34:1127-1134.
10. Pierdomenico SD, Lapenna D, Di Tommaso R, Di Carlo S, Esposito AL, Di Mascio R, Ballone E, Cuccurullo F, Mezzetti A. Blood pressure variability and cardiovascular risk in treated hypertensive patients. Am J Hypertens. 2006;19:991-997.
11. Hansen TW, Thijs L, Li Y, Boggia J, Kikuya M, Björklund- Bodegård K, Richart T, Ohkubo T, Jeppesen J, Torp-Pedersen C, Dolan E, Kuznetsova T, Stolarz-Skrzypek K, Tikhonoff V, Malyutina S, Casiglia E, Nikitin Y, Lind L, Sandoya E, Kawecka-Jaszcz K, Imai Y, Wang J, Ibsen H, O'Brien E, Staessen JA. International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes Investigators. Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations. Hypertension. 2010;55:1049-1057.
12. Rothwell PM, Howard SC, Dolan E, O'Brien E, Dobson JE, Dahlöf B, Poulter NR, Sever PS; ASCOT-BPLA and MRC Trial Investigators. Effects of beta blockers and calcium-channel blockers on within-individual variability in blood pressure and risk of stroke. Lancet Neurol. 2010;9:469-480.
13. Webb AJ, Rothwell PM. Effect of dose and combination of antihypertensives on interindividual blood pressure variability: a systematic review. Stroke. 2011;42:2860-2865.
14. Rothwell PM, Howard SC, Dolan E, O'Brien E, Dobson JE, Dahlöf B, Sever PS, Poulter NR. Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension. Lancet. 2010;375:895-905.
15. Hsieh YT, Tu ST, Cho TJ, Chang SJ, Chen JF, Hsieh MC. Visit-to-visit variability in blood pressure strongly predicts all-cause mortality in patients with type 2 diabetes: a 5·5-year prospective analysis. Eur J Clin Invest. 2012;42:245-253.
16. Verdecchia P, Angeli F, Gattobigio R, Rapicetta C, Reboldi G. Impact of blood pressure variability on cardiac and cerebrovascular complications in hypertension. Am J Hypertens. 2007;20:154-161.
17. Eguchi K, Ishikawa J, Hoshide S, Pickering TG, Schwartz JE, Shimada K, Kario K. Night time blood pressure variability is a strong predictor for cardiovascular events in patients with type 2 diabetes. Am J Hypertens. 2009;22:46-51.
18. Hansen TW, Li Y, Staessen JA. Blood pressure variability remains an elusive predictor of cardiovascular outcome. Am J Hypertens. 2009;22:3-4.
19. Staessen JA, Wang JG, Brand E, Barlassina C, Birkenhäger WH, Herrmann SM, Fagard R, Tizzoni L, Bianchi G. Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population. J Hypertens. 2001;19:1349-1358.
20. Stolarz-Skrzypek K, Kuznetsova T, Thijs L, Tikhonoff V, Seidlerová J, Richart T, Jin Y, Olszanecka A, Malyutina S, Casiglia E, Filipovský J, Kawecka-Jaszcz K, Nikitin Y, Staessen JA; European Project on Genes in Hypertension (EPOGH) Investigators. Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion. JAMA. 2011;305:1777-1785.
21. Staessen J, Bulpitt CJ, Fagard R, Joossens JV, Lijnen P, Amery A. Familial aggregation of blood pressure, anthropometric characteristics and urinary excretion of sodium and potassium-a population study in two Belgian towns. J Chronic Dis. 1985;38:397-407.
22. Kuznetsova T, Staessen JA, Kawecka-Jaszcz K, Babeanu S, Casiglia E, Filipovsky J, Nachev C, Nikitin Y, Peleskã J, O'Brien E. Quality control of the blood pressure phenotype in the European Project on Genes in Hypertension. Blood Press Monit. 2002;7:215-224.
23. World Health Organization. Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation. Geneva, Switzerland: World Health Organization; 2000.
24. Office of Population Censuses and Surveys. Classification of Occupations and Coding Index. London, United Kingdom: Her Majesty's Stationery Office; 1980.
25. Åstrand PO, Rodahl K. Textbook of Work Physiology. Physiological Bases of Exercise. New York, NY: McGraw-Hill Book Company; 1986:486-522.
26. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 2003;26(suppl 1):S5-S20.
27. Franklin SS, Larson MG, Khan SA, Wong ND, Leip EP, Kannel WB, Levy D. Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study. Circulation. 2001;103:1245-1249.
28. Mena L, Pintos S, Queipo NV, Aizpúrua JA, Maestre G, Sulbarán T. A reliable index for the prognostic significance of blood pressure variability. J Hypertens. 2005;23:505-511.
29. Gillespie BW. Use of generalized R-squared in Cox regression. APHA Scientific Session and Event Listing 2006. http://apha.confex.com/apha/134am/ techprogram/paper-135906.htm. Accessed August 15, 2012.
30. Zanchetti A. Wars, war games, and dead bodies on the battlefield: variations on the theme of blood pressure variability. Stroke. 2011;42:2722-2724.
31. Clement DL, Mussche MM, Vanhoutte G, Pannier R. Is blood pressure variability related to activity of the sympathetic system? Clin Sci. 1979;57(suppl 5):S217-S219.
32. Mancia G, Ferrari A, Gregorini L, Parati G, Pomidossi G, Bertinieri G, Grassi G, Zanchetti A. Blood pressure variability in man: its relation to high blood pressure, age and baroreflex sensitivity. Clin Sci. 1980;59(suppl 6):S401-S404.
33. Mancia G. Blood pressure variability at normal and high blood pressure. Chest. 1983;83(suppl 2):317-320.
34. Parati G, Pomidossi G, Casadei R, Groppelli A, Trazzi S, Di Rienzo M, Mancia G. Role of heart rate variability in the production of blood pressure variability in man. J Hypertens. 1987;5:557-560.
35. Frattola A, Parati G, Cuspidi C, Albini F, Mancia G. Prognostic value of 24-hour blood pressure variability. J Hypertens. 1993;11:1133-1137.
36. Sander D, Kukla C, Klingelhöfer J, Winbeck K, Conrad B. Relationship between circadian blood pressure patterns and progression of early carotid atherosclerosis: A 3-year follow-up study. Circulation. 2000;102:1536-1541.
37. Verdecchia P, Borgioni C, Ciucci A, Gattobigio R, Schillaci G, Sacchi N, Santucci A, Santucci C, Reboldi G, Porcellati C. Prognostic significance of blood pressure variability in essential hypertension. Blood Press Monit. 1996;1:3-11.
38. Rothwell PM. Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension. Lancet. 2010;375:938-948.
39. Farrell B, Godwin J, Richards S, Warlow C. The United Kingdom Transient Ischaemic Attack (UK-TIA) aspirin trial: final results. J Neurol Neurosurg Psychiatr. 1991;54:1044-1054.
40. The ESPS Group. The European Stroke Prevention Study (ESPS): principal end-points. Lancet. 1987;12:1351-1354.
41. The Dutch TIA Trial Study Group. A comparison of two doses of aspirin (30 mg vs. 283 mg a day) in patients after a transient ischemic attack or minor ischemic stroke. N Engl J Med. 1991;325:1261-1266.
42. Poulter NR, Wedel H, Dahlöf B, Sever PS, Beevers DG, Caulfield M, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J, Pocock S; ASCOT Investigators. Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA). Lancet. 2005;366:907-913.
43. Dahlöf B, Sever PS, Poulter NR, Wedel H, Beevers DG, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J; ASCOT Investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet. 2005;366:895-906.
44. Rodgers A, MacMahon S, Gamble G, Slattery J, Sandercock P, Warlow C. Blood pressure and risk of stroke in patients with cerebrovascular disease: the United Kingdom Transient Ischaemic Attack Collaborative Group. BMJ. 1996;313:147.
45. Gerin W, Rosofsky M, Pieper C, Pickering TG. A test of reproducibility of blood pressure and heart rate variability using a controlled ambulatory procedure. J Hypertens. 1993;11:1127-1131.
46. Weder AB, Julius S. Behavior, blood pressure variability, and hypertension. Psychosom Med. 1985;47:406-414.
47. Brook RD, Weder AB, Rajagopalan S. Environmental hypertensionology the effects of environmental factors on blood pressure in clinical practice and research. J Clin Hypertens (Greenwich). 2011;13:836-842.
48. Naggara O, Raymond J, Guilbert F, Roy D, Weill A, Altman DG. Analysis by categorizing or dichotomizing continuous variables is inadvisable: an example from the natural history of unruptured aneurysms. AJNR Am J Neuroradiol. 2011;32:437-440.
49. Webb AJ, Fischer U, Mehta Z, Rothwell PM. Effects of antihypertensive- drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis. Lancet. 2010;375:906-915.
50. MRC Working Party. Medical research council trial of treatment of hypertension in older adults: principal results. Br Med J. 1992;304:405-412.
51. Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002;360:1903-1913.
52. Gasowski J, Li Y, Kuznetsova T, Richart T, Thijs L, Grodzicki T, Clarke R, Staessen JA. Is "usual" blood pressure a proxy for 24-h ambulatory blood pressure in predicting cardiovascular outcomes? Am J Hypertens. 2008;21:994-1000.
53. British Cardiac Society, British Hypertension Society, Diabetes UK, HEART UK, Primary Care Cardiovascular Society, The Stroke Association. JBS 2: Joint British Societies' guidelines on prevention of cardiovascular diseases in clinical practice. Heart. 2006;91:1-52.
54. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Struijker Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Kjeldsen SE, Erdine S, Narkiewicz K, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Cifkova R, Dominiczak A, Fagard R, Heagerty AM, Laurent S, Lindholm LH, Mancia G, Manolis A, Nilsson PM, Redon J, Schmieder RE, Struijker-Boudier HA, Viigimaa M, Filippatos G, Adamopoulos S, Agabiti-Rosei E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Kiowski W, Lip G, Mallion JM, Manolis AJ, Nilsson PM, O'Brien E, Ponikowski P, Redon J, Ruschitzka F, Tamargo J, van Zwieten P, Viigimaa M, Waeber B, Williams B, Zamorano JL, The task force for the management of arterial hypertension of the European Society of Hypertension, The task force for the management of arterial hypertension of the European Society of Cardiology. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2007;28:1462-1536.
55. Staessen JA, Kuznetsova T, Stolarz K. Hypertension prevalence and stroke mortality across populations. JAMA. 2003;289:2420-2422.
56. Weinehall L, Ohgren B, Persson M, Stegmayr B, Boman K, Hallmans G, Lindholm LH. High remaining risk in poorly treated hypertension: the 'rule of halves' still exists. J Hypertens. 2002;20:2081-2088.