Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation

Science Translational Medicine

Volumn 8, Issue 359, 2016, Pages

  Cho, Josalyn L ^a   Ling, Morris F ^a   Adams, David C ^a   Faustino, Lucas ^a   Islam, Sabina A ^a   Afshar, Roshi ^a   Griffith, Jason W ^a   Harris, Robert S ^a   Ng, Aylwin ^a,b   Radicioni, Giorgia ^c   Ford, Amina A ^c   Han, Andre K ^a   Xavier, Ramnik ^a,b   Kwok, William W ^d   Boucher, Richard ^c   Moon, James J ^a   Hamilos, Daniel L ^a   Kesimer, Mehmet ^c   Suter, Melissa J ^a   Medoff, Benjamin D ^a   Luster, Andrew D ^a   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d BENAROYA RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CD45RA ANTIGEN; CXCL1 CHEMOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EOTAXIN; GAMMA INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 21; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; METHACHOLINE; MUCIN; MUCIN 5AC; SECONDARY LYMPHOID TISSUE CHEMOKINE; TRANSCRIPTION FACTOR FOXP3; CYTOKINE;

AIRBORNE PARTICLE; AIRWAY EPITHELIAL CELL; AIRWAY SMOOTH MUSCLE CELL; ALLERGENICITY; ALLERGIC AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ALLERGIC REACTION; ARTICLE; ASTHMA; BRONCHOSCOPY; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GENE EXPRESSION; HOUSE DUST ALLERGY; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; MEMORY CELL; OPTICAL COHERENCE TOMOGRAPHY; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT ALLERGY; SKIN TEST; TH2 CELL; ADULT; COMPLICATION; HYPERSENSITIVITY; IMMUNOLOGY; INFLAMMATION; LUNG; METABOLISM; MUCUS; PATHOLOGY; SMOOTH MUSCLE;

ADULT; ALLERGENS; ASTHMA; CYTOKINES; HUMANS; HYPERSENSITIVITY; INFLAMMATION; LUNG; MUCUS; MUSCLE, SMOOTH; PHENOTYPE; TH2 CELLS;

EID: 84990886705     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aag1370     Document Type: Article

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