-
2
-
-
84878833216
-
Clinical relevance of pharmacogenetics in gastrointestinal stromal tumor treatment in the era of personalized therapy
-
Angelini S, Ravegnini G, Fletcher JA, Maffei F, Hrelia P. Clinical relevance of pharmacogenetics in gastrointestinal stromal tumor treatment in the era of personalized therapy. Pharmacogenomics 14(8), 941-956 (2013).
-
(2013)
Pharmacogenomics
, vol.14
, Issue.8
, pp. 941-956
-
-
Angelini, S.1
Ravegnini, G.2
Fletcher, J.A.3
Maffei, F.4
Hrelia, P.5
-
3
-
-
84976406962
-
Pharmacogenetics of tyrosine kinase inhibitors in gastrointestinal stromal tumor and chronic myeloid leukemia
-
Ravegnini G, Samamrini G, Angelini S, Hrelia P. Pharmacogenetics of tyrosine kinase inhibitors in gastrointestinal stromal tumor and chronic myeloid leukemia. Expert Opin. Drug Metab. Toxicol. 12(7), 733-742 (2016).
-
(2016)
Expert Opin. Drug Metab. Toxicol.
, vol.12
, Issue.7
, pp. 733-742
-
-
Ravegnini, G.1
Samamrini, G.2
Angelini, S.3
Hrelia, P.4
-
4
-
-
84907398280
-
Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST)
-
Nannini M, Astolfi A, Urbini M et al. Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST). BMC Cancer 14, 685 (2014).
-
(2014)
BMC Cancer
, vol.14
, pp. 685
-
-
Nannini, M.1
Astolfi, A.2
Urbini, M.3
-
5
-
-
33646432734
-
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate
-
Prenen H, Cools J, Mentens N et al. Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clin. Cancer Res. 12(8), 2622-2627 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.8
, pp. 2622-2627
-
-
Prenen, H.1
Cools, J.2
Mentens, N.3
-
6
-
-
84938216475
-
Gastrointestinal cancer: Management of GIST-go beyond imatinib: Treat resistant subtypes
-
Pantaleo MA, Biasco G. Gastrointestinal cancer: management of GIST-go beyond imatinib: treat resistant subtypes. Nat. Rev. Clin. Oncol. 12(8), 440-442 (2015).
-
(2015)
Nat. Rev. Clin. Oncol.
, vol.12
, Issue.8
, pp. 440-442
-
-
Pantaleo, M.A.1
Biasco, G.2
-
7
-
-
84939529271
-
Personalized medicine in gastrointestinal stromal tumor (GIST): Clinical implications of the somatic and germline DNA analysis
-
Ravegnini G, Nannini M, Sammarini G et al. Personalized medicine in gastrointestinal stromal tumor (GIST): clinical implications of the somatic and germline DNA analysis. Int. J. Mol. Sci. 16(7), 15592-15608 (2015).
-
(2015)
Int. J. Mol. Sci.
, vol.16
, Issue.7
, pp. 15592-15608
-
-
Ravegnini, G.1
Nannini, M.2
Sammarini, G.3
-
8
-
-
84922732621
-
MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype
-
Ben-Hamo R, Efroni S. MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype. Oncotarget 6(3), 1594-1604 (2015).
-
(2015)
Oncotarget
, vol.6
, Issue.3
, pp. 1594-1604
-
-
Ben-Hamo, R.1
Efroni, S.2
-
9
-
-
60149088848
-
Origins and mechanisms of miRNAs and siRNAs
-
Carthew RW, Sontheimer EJ. Origins and mechanisms of miRNAs and siRNAs. Cell 136(4), 642-655 (2009).
-
(2009)
Cell
, vol.136
, Issue.4
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
11
-
-
84939498496
-
MiRNA profiling in gastrointestinal stromal tumors: Implication as diagnostic and prognostic markers
-
Nannini M, Ravegnini G, Angelini S, Astolfi A, Biasco G, Pantaleo MA. miRNA profiling in gastrointestinal stromal tumors: implication as diagnostic and prognostic markers. Epigenomics 7(6), 1033-1049 (2015).
-
(2015)
Epigenomics
, vol.7
, Issue.6
, pp. 1033-1049
-
-
Nannini, M.1
Ravegnini, G.2
Angelini, S.3
Astolfi, A.4
Biasco, G.5
Pantaleo, M.A.6
-
12
-
-
84990847232
-
-
miRBase: The microRNA database
-
miRBase: the microRNA database. http://microrna.sanger.ac.uk
-
-
-
-
13
-
-
84990847251
-
-
INGENUITY. www.ingenuity.com
-
-
-
-
14
-
-
84892692245
-
Insulin-like growth factor (IGF) system and gastrointestinal stromal tumours (GIST): Present and future
-
Nannini M, Biasco G, Astolfi A, Urbini M, Pantaleo MA. Insulin-like growth factor (IGF) system and gastrointestinal stromal tumours (GIST): present and future. Histol. Histopathol. 29(2), 167-175 (2014).
-
(2014)
Histol. Histopathol.
, vol.29
, Issue.2
, pp. 167-175
-
-
Nannini, M.1
Biasco, G.2
Astolfi, A.3
Urbini, M.4
Pantaleo, M.A.5
-
15
-
-
84990870064
-
-
Target Scan
-
Target Scan. www.targetscan.org
-
-
-
-
16
-
-
84871412667
-
Expression of IGF-1 receptor in KIT/PDGF receptor-α wild-type gastrointestinal stromal tumors with succinate dehydrogenase complex dysfunction
-
Nannini M, Astolfi A, Paterini P et al. Expression of IGF-1 receptor in KIT/PDGF receptor-α wild-type gastrointestinal stromal tumors with succinate dehydrogenase complex dysfunction. Future Oncol. 9(1), 121-126 (2013).
-
(2013)
Future Oncol.
, vol.9
, Issue.1
, pp. 121-126
-
-
Nannini, M.1
Astolfi, A.2
Paterini, P.3
-
17
-
-
78049495856
-
Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification
-
Janeway KA, Zhu MJ, Barretina J, Perez-Atayde A, Demetri GD, Fletcher JA. Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification. Int. J. Cancer 127(11), 2718-2722 (2010).
-
(2010)
Int. J. Cancer
, vol.127
, Issue.11
, pp. 2718-2722
-
-
Janeway, K.A.1
Zhu, M.J.2
Barretina, J.3
Perez-Atayde, A.4
Demetri, G.D.5
Fletcher, J.A.6
-
18
-
-
72449212435
-
Insulin-like growth factor 1 receptor expression in wild-type GISTs: A potential novel therapeutic target
-
Pantaleo MA, Astolfi A, Di Battista M et al. Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target. Int. J. Cancer 125(12), 2991-2994 (2009).
-
(2009)
Int. J. Cancer
, vol.125
, Issue.12
, pp. 2991-2994
-
-
Pantaleo, M.A.1
Astolfi, A.2
Di Battista, M.3
-
19
-
-
84861991534
-
MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type i insulinlike growth factor receptor
-
Shen K, Liang Q, Xu K et al. MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulinlike growth factor receptor. Biochem. Pharmacol. 84(3), 320-330 (2012).
-
(2012)
Biochem. Pharmacol.
, vol.84
, Issue.3
, pp. 320-330
-
-
Shen, K.1
Liang, Q.2
Xu, K.3
-
20
-
-
84935501185
-
MicroRNA-139-5p inhibits cell proliferation and invasion by targeting insulin-like growth factor 1 receptor in human non-small-cell lung cancer
-
Xu W, Hang M, Yuan CY, Wu FL, Chen SB, Xue K. MicroRNA-139-5p inhibits cell proliferation and invasion by targeting insulin-like growth factor 1 receptor in human non-small-cell lung cancer. Int. J. Clin. Exp. Pathol. 8(4), 3864-3870 (2015).
-
(2015)
Int. J. Clin. Exp. Pathol.
, vol.8
, Issue.4
, pp. 3864-3870
-
-
Xu, W.1
Hang, M.2
Yuan, C.Y.3
Wu, F.L.4
Chen, S.B.5
Xue, K.6
-
21
-
-
84901190431
-
IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma
-
Gao L, Wang X, Zhang L et al. IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma. Oncotarget 5(9), 2562-2574 (2014).
-
(2014)
Oncotarget
, vol.5
, Issue.9
, pp. 2562-2574
-
-
Gao, L.1
Wang, X.2
Zhang, L.3
-
22
-
-
84911458551
-
Let-7b-5p regulates proliferation and apoptosis in multiple myeloma by targeting IGF1R
-
Xu H, Liu C, Zhang Y et al. Let-7b-5p regulates proliferation and apoptosis in multiple myeloma by targeting IGF1R. Acta Biochim. Biophys. Sin. (Shanghai) 46(11), 965-972 (2014).
-
(2014)
Acta Biochim. Biophys. Sin. (Shanghai)
, vol.46
, Issue.11
, pp. 965-972
-
-
Xu, H.1
Liu, C.2
Zhang, Y.3
-
23
-
-
34249033020
-
MicroRNA detection and target prediction: Integration of computational and experimental approaches
-
Chaudhuri K, Chatterjee R. MicroRNA detection and target prediction: integration of computational and experimental approaches. DNA Cell. Biol. 26(5), 321-337 (2007).
-
(2007)
DNA Cell. Biol.
, vol.26
, Issue.5
, pp. 321-337
-
-
Chaudhuri, K.1
Chatterjee, R.2
-
24
-
-
85005769283
-
Quadruple wild-type (WT) GIST: Defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways
-
Pantaleo MA, Nannini M, Corless CL, Heinrich MC. Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways. Cancer Med. 4(1), 101-103 (2015).
-
(2015)
Cancer Med.
, vol.4
, Issue.1
, pp. 101-103
-
-
Pantaleo, M.A.1
Nannini, M.2
Corless, C.L.3
Heinrich, M.C.4
-
25
-
-
84962440911
-
Targeting CDK4 and CDK6: From discovery to therapy
-
Sherr CJ, Beach D, Shapiro GI. Targeting CDK4 and CDK6: from discovery to therapy. Cancer Discov. 6(4), 353-367 (2015).
-
(2015)
Cancer Discov.
, vol.6
, Issue.4
, pp. 353-367
-
-
Sherr, C.J.1
Beach, D.2
Shapiro, G.I.3
-
26
-
-
84952059517
-
MiRNA signature identification of retinoblastoma and the correlations between differentially expressed miRNAs during retinoblastoma progression
-
Yang Y, Mei Q. miRNA signature identification of retinoblastoma and the correlations between differentially expressed miRNAs during retinoblastoma progression. Mol. Vis. 21, 1307-1317 (2015).
-
(2015)
Mol. Vis.
, vol.21
, pp. 1307-1317
-
-
Yang, Y.1
Mei, Q.2
-
27
-
-
79957647418
-
Aging and microRNA expression in human skeletal muscle: A microarray and bioinformatics analysis
-
Drummond MJ, McCarthy JJ, Sinha M et al. Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis. Physiol. Genomics 43(10), 595-603 (2011).
-
(2011)
Physiol. Genomics
, vol.43
, Issue.10
, pp. 595-603
-
-
Drummond, M.J.1
McCarthy, J.J.2
Sinha, M.3
-
28
-
-
46149089421
-
Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression
-
Godar S, Ince TA, Bell GW et al. Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell 134(1), 62-73 (2008).
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 62-73
-
-
Godar, S.1
Ince, T.A.2
Bell, G.W.3
-
29
-
-
23044491699
-
The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer
-
Miletti-González KE, Chen S, Muthukumaran N et al. The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer. Cancer Res. 65(15), 6660-6667 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.15
, pp. 6660-6667
-
-
Miletti-González, K.E.1
Chen, S.2
Muthukumaran, N.3
-
30
-
-
77950561915
-
CD44, a therapeutic target for metastasising tumours
-
Orian-Rousseau V. CD44, a therapeutic target for metastasising tumours. Eur. J. Cancer 46(7), 1271-1277 (2010).
-
(2010)
Eur. J. Cancer
, vol.46
, Issue.7
, pp. 1271-1277
-
-
Orian-Rousseau, V.1
-
31
-
-
83055186465
-
CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers
-
Chen J, Guo T, Zhang L et al. CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers. Genes Chrom. Cancer 51(2), 186-195 (2012).
-
(2012)
Genes Chrom. Cancer
, vol.51
, Issue.2
, pp. 186-195
-
-
Chen, J.1
Guo, T.2
Zhang, L.3
-
32
-
-
84944512794
-
ETV1 mRNA is specifically expressed in gastrointestinal stromal tumors
-
Jang BG, Lee HE, Kim WH. ETV1 mRNA is specifically expressed in gastrointestinal stromal tumors. Virchows Arch. 467(4), 393-403 (2015).
-
(2015)
Virchows Arch.
, vol.467
, Issue.4
, pp. 393-403
-
-
Jang, B.G.1
Lee, H.E.2
Kim, W.H.3
-
33
-
-
34250623276
-
Significance of CD44 expression in gastrointestinal stromal tumors in relation to disease progression and survival
-
Hsu KH, Tsai HW, Shan YS, Lin PW. Significance of CD44 expression in gastrointestinal stromal tumors in relation to disease progression and survival. World J. Surg. 31(7), 1438-1444 (2007).
-
(2007)
World J. Surg.
, vol.31
, Issue.7
, pp. 1438-1444
-
-
Hsu, K.H.1
Tsai, H.W.2
Shan, Y.S.3
Lin, P.W.4
-
34
-
-
79955598536
-
Expression of CD44 3'-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis
-
Jeyapalan Z, Deng Z, Shatseva T, Fang L, He C, Yang BB. Expression of CD44 3'-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis. Nucleic Acids Res.39(8), 3026-3041 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, Issue.8
, pp. 3026-3041
-
-
Jeyapalan, Z.1
Deng, Z.2
Shatseva, T.3
Fang, L.4
He, C.5
Yang, B.B.6
|