메뉴 건너뛰기




Volumn 6, Issue 3, 2015, Pages 1594-1604

MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype

Author keywords

Cancer; microRNA; Phenotype; Regulation; Signaling pathways

Indexed keywords

ESTROGEN RECEPTOR; MICRORNA; MICRORNA 181A 1; MICRORNA 193B; MICRORNA 199A 2; MICRORNA 203; MICRORNA 214; MICRORNA 221; MICRORNA 30E; MICRORNA 324; MICRORNA 375; MICRORNA 532; UNCLASSIFIED DRUG;

EID: 84922732621     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2734     Document Type: Article
Times cited : (46)

References (58)
  • 1
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nature reviews Cancer. 2006; 6:857-866.
    • (2006) Nature reviews Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 2
    • 80052041185 scopus 로고    scopus 로고
    • MicroRNA regulation by RNA-binding proteins and its implications for cancer
    • van Kouwenhove M, Kedde M, Agami R. MicroRNA regulation by RNA-binding proteins and its implications for cancer. Nature reviews Cancer. 2011; 11:644-656.
    • (2011) Nature reviews Cancer , vol.11 , pp. 644-656
    • van Kouwenhove, M.1    Kedde, M.2    Agami, R.3
  • 3
    • 34250841756 scopus 로고    scopus 로고
    • MicroRNAs in human cancer: from research to therapy
    • Negrini M, Ferracin M, Sabbioni S, Croce CM. MicroRNAs in human cancer: from research to therapy. J Cell Sci. 2007; 120:1833-1840.
    • (2007) J Cell Sci , vol.120 , pp. 1833-1840
    • Negrini, M.1    Ferracin, M.2    Sabbioni, S.3    Croce, C.M.4
  • 4
    • 70349320158 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation in cancer
    • Croce CM. Causes and consequences of microRNA dysregulation in cancer. Nature reviews Genetics. 2009; 10:704-714.
    • (2009) Nature reviews Genetics , vol.10 , pp. 704-714
    • Croce, C.M.1
  • 5
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, Benz CC. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem. 2007; 282:1479-1486.
    • (2007) J Biol Chem , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 8
    • 81855224576 scopus 로고    scopus 로고
    • Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
    • Kasinski AL, Slack FJ. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nature reviews Cancer. 2011; 11:849-864.
    • (2011) Nature reviews Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 13
    • 80053074068 scopus 로고    scopus 로고
    • MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity
    • Lu TX, Hartner J, Lim EJ, Fabry V, Mingler MK, Cole ET, Orkin SH, Aronow BJ, Rothenberg ME. MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity. J Immunol. 2011; 187:3362-3373.
    • (2011) J Immunol , vol.187 , pp. 3362-3373
    • Lu, T.X.1    Hartner, J.2    Lim, E.J.3    Fabry, V.4    Mingler, M.K.5    Cole, E.T.6    Orkin, S.H.7    Aronow, B.J.8    Rothenberg, M.E.9
  • 14
    • 84861567957 scopus 로고    scopus 로고
    • MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma
    • Fang Y, Xue JL, Shen Q, Chen J, Tian L. MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma. Hepatology. 2012; 55:1852-1862.
    • (2012) Hepatology , vol.55 , pp. 1852-1862
    • Fang, Y.1    Xue, J.L.2    Shen, Q.3    Chen, J.4    Tian, L.5
  • 17
    • 80355128968 scopus 로고    scopus 로고
    • MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart
    • Glass C, Singla DK. MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart. American journal of physiology Heart and circulatory physiology. 2011; 301:H2038-2049.
    • (2011) American journal of physiology Heart and circulatory physiology , vol.301 , pp. H2038-H2049
    • Glass, C.1    Singla, D.K.2
  • 18
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
    • Ponomarev ED, Veremeyko T, Barteneva N, Krichevsky AM, Weiner HL. MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nature medicine. 2011; 17:64-70.
    • (2011) Nature medicine , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4    Weiner, H.L.5
  • 20
    • 79959805164 scopus 로고    scopus 로고
    • miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • Dweep H, Sticht C, Pandey P, Gretz N. miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. Journal of biomedical informatics. 2011; 44:839-847.
    • (2011) Journal of biomedical informatics , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 21
    • 0036020892 scopus 로고    scopus 로고
    • A direct approach to false discovery rates
    • Storey JD. A direct approach to false discovery rates. J Roy Stat Soc B. 2002; 64:479-498.
    • (2002) J Roy Stat Soc B , vol.64 , pp. 479-498
    • Storey, J.D.1
  • 22
    • 37849022459 scopus 로고    scopus 로고
    • Identification of key processes underlying cancer phenotypes using biologic pathway analysis
    • Efroni S, Schaefer CF, Buetow KH. Identification of key processes underlying cancer phenotypes using biologic pathway analysis. PloS one. 2007; 2:e425.
    • (2007) PloS one , vol.2
    • Efroni, S.1    Schaefer, C.F.2    Buetow, K.H.3
  • 23
    • 84907023028 scopus 로고    scopus 로고
    • Correction: Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression
    • Ben-Hamo R, Efroni S. Correction: Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression. Genome medicine. 2012; 4:87.
    • (2012) Genome medicine , vol.4 , pp. 87
    • Ben-Hamo, R.1    Efroni, S.2
  • 24
    • 84897989566 scopus 로고    scopus 로고
    • Network as biomarker: Quantifying transcriptional co-expression to stratify cancer clinical phenotypes
    • Ben-Hamo Rotem ES. Network as biomarker: Quantifying transcriptional co-expression to stratify cancer clinical phenotypes. Systems Biomedicine. 2013; 1.
    • (2013) Systems Biomedicine , pp. 1
    • Ben-Hamo Rotem, E.S.1
  • 28
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes
    • Bjornstrom L, Sjoberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol. 2005; 19:833-842.
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Bjornstrom, L.1    Sjoberg, M.2
  • 30
    • 0032423729 scopus 로고    scopus 로고
    • Steroid hormone receptors in breast cancer management
    • Osborne CK. Steroid hormone receptors in breast cancer management. Breast cancer research and treatment. 1998; 51:227-238.
    • (1998) Breast cancer research and treatment , vol.51 , pp. 227-238
    • Osborne, C.K.1
  • 32
    • 77952302285 scopus 로고    scopus 로고
    • The role of estrogen receptor beta (ERbeta) in malignant diseases-a new potential target for antiproliferative drugs in prevention and treatment of cancer
    • Warner M, Gustafsson JA. The role of estrogen receptor beta (ERbeta) in malignant diseases-a new potential target for antiproliferative drugs in prevention and treatment of cancer. Biochemical and biophysical research communications. 2010; 396:63-66.
    • (2010) Biochemical and biophysical research communications , vol.396 , pp. 63-66
    • Warner, M.1    Gustafsson, J.A.2
  • 33
    • 84855593872 scopus 로고    scopus 로고
    • Biomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies
    • Ben-Hamo R, Efroni S. Biomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies. BMC systems biology. 2012; 6.
    • (2012) BMC systems biology , pp. 6
    • Ben-Hamo, R.1    Efroni, S.2
  • 38
    • 77953411618 scopus 로고    scopus 로고
    • MicroRNA-466l upregulates IL-10 expression in TLRtriggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation
    • Ma F, Liu X, Li D, Wang P, Li N, Lu L, Cao X. MicroRNA-466l upregulates IL-10 expression in TLRtriggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J Immunol. 2010; 184:6053-6059.
    • (2010) J Immunol , vol.184 , pp. 6053-6059
    • Ma, F.1    Liu, X.2    Li, D.3    Wang, P.4    Li, N.5    Lu, L.6    Cao, X.7
  • 40
    • 84865442439 scopus 로고    scopus 로고
    • Atomistic mechanism of microRNA translation upregulation via molecular dynamics simulations
    • Ye W, Qin F, Zhang J, Luo R, Chen HF. Atomistic mechanism of microRNA translation upregulation via molecular dynamics simulations. PloS one. 2012; 7:e43788.
    • (2012) PloS one , vol.7
    • Ye, W.1    Qin, F.2    Zhang, J.3    Luo, R.4    Chen, H.F.5
  • 41
    • 77949426688 scopus 로고    scopus 로고
    • A novel microRNA and transcription factor mediated regulatory network in schizophrenia
    • Guo AY, Sun J, Jia P, Zhao Z. A novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC systems biology. 2010; 4:10.
    • (2010) BMC systems biology , vol.4 , pp. 10
    • Guo, A.Y.1    Sun, J.2    Jia, P.3    Zhao, Z.4
  • 42
    • 68349092641 scopus 로고    scopus 로고
    • Clustered microRNAs' coordination in regulating proteinprotein interaction network
    • Yuan X, Liu C, Yang P, He S, Liao Q, Kang S, Zhao Y. Clustered microRNAs' coordination in regulating proteinprotein interaction network. BMC systems biology. 2009; 3:65.
    • (2009) BMC systems biology , vol.3 , pp. 65
    • Yuan, X.1    Liu, C.2    Yang, P.3    He, S.4    Liao, Q.5    Kang, S.6    Zhao, Y.7
  • 43
    • 45749124784 scopus 로고    scopus 로고
    • A computational screen for mouse signaling pathways targeted by microRNA clusters
    • Xu J, Wong C. A computational screen for mouse signaling pathways targeted by microRNA clusters. RNA. 2008; 14:1276-1283.
    • (2008) RNA , vol.14 , pp. 1276-1283
    • Xu, J.1    Wong, C.2
  • 44
    • 77956117850 scopus 로고    scopus 로고
    • Towards computational prediction of microRNA function and activity
    • Ulitsky I, Laurent LC, Shamir R. Towards computational prediction of microRNA function and activity. Nucleic acids research. 2010; 38:e160.
    • (2010) Nucleic acids research , vol.38
    • Ulitsky, I.1    Laurent, L.C.2    Shamir, R.3
  • 45
    • 84870356525 scopus 로고    scopus 로고
    • miR2Gene: pattern discovery of single gene, multiple genes, and pathways by enrichment analysis of their microRNA regulators
    • Qiu C, Wang J, Cui Q. miR2Gene: pattern discovery of single gene, multiple genes, and pathways by enrichment analysis of their microRNA regulators. BMC systems biology. 2011; 5Suppl 2:S9.
    • (2011) BMC systems biology , vol.5 , pp. S9
    • Qiu, C.1    Wang, J.2    Cui, Q.3
  • 46
    • 38549092089 scopus 로고    scopus 로고
    • miRGator: an integrated system for functional annotation of microRNAs
    • Nam S, Kim B, Shin S, Lee S. miRGator: an integrated system for functional annotation of microRNAs. Nucleic acids research. 2008; 36:D159-164.
    • (2008) Nucleic acids research , vol.36 , pp. D159-D164
    • Nam, S.1    Kim, B.2    Shin, S.3    Lee, S.4
  • 48
    • 80052223077 scopus 로고    scopus 로고
    • microRNAassociated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer
    • Buffa FM, Camps C, Winchester L, Snell CE, Gee HE, Sheldon H, Taylor M, Harris AL, Ragoussis J. microRNAassociated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer research. 2011; 71:5635-5645.
    • (2011) Cancer research , vol.71 , pp. 5635-5645
    • Buffa, F.M.1    Camps, C.2    Winchester, L.3    Snell, C.E.4    Gee, H.E.5    Sheldon, H.6    Taylor, M.7    Harris, A.L.8    Ragoussis, J.9
  • 52
    • 44149083586 scopus 로고    scopus 로고
    • miRDB: a microRNA target prediction and functional annotation database with a wiki interface
    • Wang X. miRDB: a microRNA target prediction and functional annotation database with a wiki interface. RNA. 2008; 14:1012-1017.
    • (2008) RNA , vol.14 , pp. 1012-1017
    • Wang, X.1
  • 55
    • 4644237189 scopus 로고    scopus 로고
    • Fast and effective prediction of microRNA/target duplexes
    • Rehmsmeier M, Steffen P, Hochsmann M, Giegerich R. Fast and effective prediction of microRNA/target duplexes. RNA. 2004; 10:1507-1517.
    • (2004) RNA , vol.10 , pp. 1507-1517
    • Rehmsmeier, M.1    Steffen, P.2    Hochsmann, M.3    Giegerich, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.