Alleviation of Lead-Induced Apoptosis by Puerarin via Inhibiting Mitochondrial Permeability Transition Pore Opening in Primary Cultures of Rat Proximal Tubular Cells

Biological Trace Element Research

Volumn 174, Issue 1, 2016, Pages 166-176

  Wang, Zhong Kun ^a   Zhou, Xue Lei ^b   Song, Xiang Bin ^a   Zhuang, Dong Ming ^c   Wang, Zhen Yong ^a   Yang, Du Bao ^a   Wang, Lin ^a  

^a SHANDONG AGRICULTURAL UNIVERSITY   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Lead; Mitochondria; Mitochondrial permeability transition; Proximal tubular cells; Puerarin

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENINE NUCLEOTIDE TRANSLOCASE 1; ADENINE NUCLEOTIDE TRANSLOCASE 2; ADENOSINE TRIPHOSPHATE; CASPASE 3; CASPASE 9; CYTOCHROME C; LEAD; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PUERARIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; ISOFLAVONE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MITOCHONDRIAL PERMEABILITY; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; RENAL PROTECTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PRIMARY CELL CULTURE;

ANIMALS; APOPTOSIS; CELLS, CULTURED; ISOFLAVONES; KIDNEY TUBULES, PROXIMAL; LEAD; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; PRIMARY CELL CULTURE; RATS;

EID: 84990247441     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-016-0701-8     Document Type: Article

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