Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead

Archives of Toxicology

Volumn 90, Issue 5, 2016, Pages 1193-1209

  Liu, Gang ^a,b   Wang, Zhong Kun ^a   Wang, Zhen Yong ^a   Yang, Du Bao ^a   Liu, Zong Ping ^b   Wang, Lin ^a  

^a SHANDONG AGRICULTURAL UNIVERSITY   (China)

^b YANGZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Lead; Mitochondria; Mitochondrial permeability transition; Primary cell culture; Proximal tubular cells

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENINE NUCLEOTIDE TRANSLOCASE 1; ADENINE NUCLEOTIDE TRANSLOCASE 2; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CASPASE 3; CYTOCHROME C; LEAD; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 1; CARRIER PROTEIN; CASP3 PROTEIN, RAT; LEAD ACETATE; ORGANOMETALLIC COMPOUND;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CHANNEL GATING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ENZYME ACTIVATION; ENZYME RELEASE; EXPOSURE; FLOW CYTOMETRY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MALE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; MITOCHONDRION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CASPASE 3; CELLS, CULTURED; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; KIDNEY TUBULES, PROXIMAL; MALE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; ORGANOMETALLIC COMPOUNDS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84931095136     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-015-1547-0     Document Type: Article

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