Emergence of Escherichia coli sequence type 131 (ST131) and st3948 with KPC-2, KPC-3 and KPC-8 carbapenemases from a long-term care and rehabilitation facility (LTCRF) in Northern Italy

Advances in Experimental Medicine and Biology

Volumn 901, Issue , 2016, Pages 77-89

  Piazza, Aurora ^a   Caltagirone, Mariasofia ^a   Bitar, Ibrahim ^a   Nucleo, Elisabetta ^a   Spalla, Melissa ^a   Fogato, Elena ^b   D’Angelo, Roberto ^b   Pagani, Laura ^a   Migliavacca, Roberta ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b ASP Golgi Redaelli   (Italy)

Author keywords

KPC positive E. coli; Long term care and rehabilitation facility; Sequence type 131 (ST131); ST3948

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; CARBAPENEMASE; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; MEROPENEM; PIPERACILLIN; QUINOLONE DERIVATIVE; TIGECYCLINE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE; ESCHERICHIA COLI PROTEIN;

AGED; ALLELE; ANTIBIOTIC SENSITIVITY; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CONJUGATION; BACTERIUM ISOLATE; CARBAPENEMASE PRODUCING ENTEROBACTERIACEAE; CLINICAL ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; HUMAN; ITALY; MALE; MIC50; MIC90; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PHENOTYPE; PHYLOGENY; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; REPETITIVE SEQUENCE BASED POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; VERY ELDERLY; CLASSIFICATION; COMMUNICABLE DISEASES, EMERGING; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; NURSING HOME; REHABILITATION CENTER; STATISTICS AND NUMERICAL DATA;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; COMMUNICABLE DISEASES, EMERGING; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FEMALE; HUMANS; ITALY; MALE; MULTILOCUS SEQUENCE TYPING; PHYLOGENY; REHABILITATION CENTERS; SKILLED NURSING FACILITIES;

EID: 84990201116     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/5584_2015_5017     Document Type: Chapter

References (44)

1. Accogli M, Giani T, Monaco M et al (2014) Emergence of Escherichia coli ST131 sub-clone H30 producing VIM-1 and KPC-3 carbapenemases, Italy. J Antimicrob Chemother 69(8):2293-2296. doi:10.1093/jac/dku132
2. Almeida AC, deSáCavalcanti FL, Vilela MA et al (2012) Escherichia coli ST502 and Klebsiella pneumoniae ST11 sharing an IncW plasmid harbouring the bla (KPC-2) gene in an Intensive Care Unit patient. Int J Antimicrob Agents 40(4):374-376
3. Arnoldo L, Migliavacca R, Regattin L et al (2013) Prevalence of urinary colonization by extended spectrumbeta-lactamase Enterobacteriaceae among catheterized inpatients in Italian long term care facilities. BMC Infect Dis 13:124. doi:10.1186/1471-2334-13-124
4. Baraniak A, Grabowska A, Izdebski R et al (2011) Molecular characteristics of KPC-producing Enterobacteriaceae at the early stage of their dissemination in Poland, 2008-2009. Antimicrob Agents Chemother 55(12):5493-5499
5. Basic Local Alignment Search Tool. http://blast.ncbi.nlm. nih.gov/Blast.cgi
6. Brisse S, Diancourt L, Laouenan C et al (2012) Phylogenetic distribution of CTX-M-and non-extended-spectrum-beta-lactamase-producing Escherichia coli isolates: group B2 isolates, except clone ST131, rarely produce CTX-M enzymes. J Clin Microbiol 50:2974-2981
7. Brolund A, Hæggman S, Edquist PJ et al (2010) The DiversiLab system versus pulsed-field gel electrophoresis: characterisation of extended spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae. J Microbiol Methods 83(2):224-230. doi:10.1016/j.mimet.2010.09.004
8. Burke L, Humphreys H, Fitzgerald-Hughes D (2012) The revolving door between hospital and community: extended-spectrum beta-lactamase producing Escherichia coli in Dublin. J Hosp Infect 81:192-198
9. Cai JC, Zhang R, Hu YY et al (2014) Emergence of Escherichia coli sequence type 131 isolates producing KPC-2 carbapenemase in China. Antimicrob Agents Chemother 58(2):1146-1152. doi:10.1128/AAC.00912-13
10. Carattoli A, Bertini A, Villa L et al (2005) Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 63(3):219-228
11. Clermont O, Bonacorsi S, Bingen E (2000) Rapid and simple determination of the Escherichia coli phylogenetic group. Appl Environ Microbiol 66(10):4555-4558
12. Clermont O, Dhanji H, Upton M et al (2009) Rapid detection of the O25b-ST131 clone of Escherichia coli encompassing the CTX-M-15-producing strains. J Antimicrob Chemother 64(2):274-277
13. Colomer-Lluch M, Mora A, Lopez C et al (2013) Detection of quinolone-resistant Escherichia coli isolates belonging to clonal groups O25b:H4-B2-ST131 and O25b:H4-D-ST69 in raw sewage and river water in Barcelona, Spain. J Antimicrob Chemother 68:758-765
14. Coque TM, Novais A, Carattoli A et al (2008) Dissemination of clonally related Escherichia coli strains expressing extended-spectrum beta-lactamase CTX-M-15. Emerg Infect Dis 14(2):195-200
15. Deshpande LM, Rhomberg PR, Sader HS et al (2006) Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States Medical Centers: report from the MYSTIC Program (1999-2005). Diagn Microbiol Infect Dis 56(4):367-372 European Committee on Antimicrobial Susceptibility Testing. http://eucast.org/clinical_breakpoints
16. Ghodousi A, Bonura C, Di Noto AM et al (2015) Extended-spectrum ß-lactamase, AmpC-producing, and fluoroquinolone-resistant Escherichia coli in retail broiler chicken meat, Italy. Foodborne Pathog Dis 12 (7):619-625. doi:10.1089/fpd.2015.1936
17. Giakkoupi P, Pappa O, Polemis M et al (2009) Emerging Klebsiella pneumoniae isolates coproducing KPC-2 and VIM-1 carbapenemases. Antimicrob Agents Chemother 53(9):4048-4050
18. Giani T, Pini B, Arena F et al (2013) Epidemic diffusion of KPC carbapenemase-producing Klebsiella pneumoniae in Italy: results of the first countrywide survey, 15 May to 30 June 2011. Euro Surveill 18(22)
19. Gijón D, Curiao T, Baquero F et al (2012) Fecal carriage of carbapenemase-producing Enterobacteriaceae: a hidden reservoir in hospitalized and non-hospitalized patients. J Clin Microbiol 50(5):1558-1563
20. Gona F, Barbera F, Pasquariello AC et al (2014) In vivo multiclonal transfer of bla(KPC-3) from Klebsiella pneumoniae to Escherichia coli in surgery patients. Clin Microbiol Infect 20(10):O633-O635. doi:10.1111/1469-0691.12577
21. Goren MG, Navon-Venezia S, Chmelnitsky I et al (2010) Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. Antimicrob Agents Chemother 54(6):2687-2691. doi:10.1128/AAC.01359-09
22. Grundmann H, Livermore DM, Giske CG et al (2010) Carbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts. Euro Surveill 15(46)
23. Kim YA, Qureshi ZA, Adams-Haduch JM et al (2012) Features of infections due to Klebsiella pneumoniae carbapenemase-producing Escherichia coli: emergence of sequence type 131. Clin Infect Dis 55(2):224-231
24. Lau SH, Kaufmann ME, Livermore DM et al (2008) UK epidemic Escherichia coli strains A-E, with CTX-M-15 beta-lactamase, all belong to the international O25: H4-ST131 clone. J Antimicrob Chemother 62 (6):1241-1244
25. Ma L, Siu LK, Lin JC et al (2013) Updated molecular epidemiology of carbapenem-nonsusceptible Escherichia coli in Taiwan: first identification of KPC-2 or NDM-1-producing E. coli in Taiwan. BMC Infect Dis 13:599. doi:10.1186/1471-2334-13-599
26. Mavroidi A, Miriagou V, Malli E et al (2012) Emergence of Escherichia coli sequence type 410 (ST410) with KPC-2 β-lactamase. Int J Antimicrob Agents 39 (3):247-250
27. Miriagou V, Cornaglia G, Edelstein M et al (2010) Acquired carbapenemases in Gram-negative bacterial pathogens: detection and surveillance issues. Clin Microbiol Infect 16(2):112-122. doi:10.1111/j.1469-0691.2009.03116.x
28. Morris D, Boyle F, Ludden C et al (2011) Production of KPC-2 carbapenemase by an Escherichia coli clinical isolate belonging to the international ST131 clone. Antimicrob Agents Chemother 55(10):4935-4936. doi:10.1128/AAC.05127-11
29. Multi Locus Sequence Typing scheme from the website of the University of Warwick. http://mlst.warwick.ac.uk/mlst/dbs/Ecoli
30. Naas T, Cuzon G, Gaillot O et al (2011) When carbapenem-hydrolyzing beta-lactamase Kpc meets Escherichia coli ST131 in France. Antimicrob Agents Chemother 55(10):4933-4934. doi:10.1128/AAC.00719-11
31. Nicolas-Chanoine MH, Robert J, Vigan M et al (2013) Different factors associated with CTX-M-producing ST131 and non-ST131 Escherichia coli clinical isolates. PLoS One 8(9), e72191
32. Nicolas-Chanoine MH, Bertrand X, Madec JY (2014) Escherichia coli ST131, an intriguing clonal group. Clin Microbiol Rev 27(3):543-574. doi:10.1128/CMR.00125-13
33. O’Hara JA, Hu F, Ahn C et al (2014) Molecular epidemiology of KPC-producing Escherichia coli: occurrence of ST131-fimH30 subclone harboring pKpQIL-like IncFIIk plasmid. Antimicrob Agents Chemother 58 (7):4234-4237. doi:10.1128/AAC.02182-13
34. Pagani L, Migliavacca R, Pallecchi L et al (2002) Emerging extended-spectrum beta-lactamases in Proteus mirabilis. J Clin Microbiol 40(4):1549-1552
35. Petrella S, Ziental-Gelus N, Mayer C et al (2008) Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A betalactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France. Antimicrob Agents Chemother 52(10):3725-3736. doi:10.1128/AAC.00163-08
36. Platell JL, Johnson JR, Cobbold RN et al (2011) Multidrug-resistant extraintestinal pathogenic Escherichia coli of sequence type ST131 in animals and foods. Vet Microbiol 153(1-2):99-108. doi:10.1016/j.vetmic.2011.05.007
37. Pomba C, López-Cerero L, Bellido M et al (2014) Withinlineage variability of ST131 Escherichia coli isolates from humans and companion animals in the south of Europe. J Antimicrob Chemother 69(1):271-273. doi:10.1093/jac/dkt343
38. Richter SN, Frasson I, Bergo C et al (2011) Transfer of KPC-2 Carbapenemase from Klebsiella pneumoniae to Escherichia coli in a patient: first case in Europe. J Clin Microbiol 49(5):2040-2042. doi:10.1128/JCM.00133-11
39. Ruiz-Garbajosa P, Curiao T, Tato M et al (2013) Multiclonal dispersal of KPC genes following the emergence of non-ST258 KPC-producing Klebsiella pneumoniae clones in Madrid, Spain. J Antimicrob Chemother 68(11):2487-2492
40. Tenover FC, Arbeit RD, Goering RV et al (1995) Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33 (9):2233-2239
41. Tzelepi E, Magana C, Platsouka E et al (2003) Extendedspectrum beta-lactamase types in Klebsiella pneumoniae and Escherichia coli in two Greek hospitals. Int J Antimicrob Agents 21(3):285-288
42. Urban C, Bradford PA, Tuckman M et al (2008) Carbapenem-resistant Escherichia coli harboring Klebsiella pneumoniae carbapenemase betalactamases associated with long-term care facilities. Clin Infect Dis 46(11):e127-e130. doi:10.1086/588048
43. Viau RA, Hujer AM, Marshall SH et al (2012) “Silent” dissemination of Klebsiella pneumoniae isolates bearing K. pneumoniae carbapenemase in a long-term care facility for children and young adults in Northeast Ohio. Clin Infect Dis 54(9):1314-1321. doi:10.1093/cid/cis036
44. Wirth T, Falush D, Lan R et al (2006) Sex and virulence in Escherichia coli: an evolutionary perspective. Mol Microbiol 60(5):1136-1151