Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A β-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 10, 2008, Pages 3725-3736

  Petrella, Stephanie ^a   Ziental Gelus, Nathalie ^b   Mayer, Claudine ^b   Renard, Murielle ^c   Jarlier, Vincent ^a,c   Sougakoff, Wladimir ^b,c  

^a SORBONNE UNIVERSITÉ   (France)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; BETA LACTAMASE; CEFOTAXIME; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CITRIC ACID; GLUTAMIC ACID; IMIPENEM; LYSINE; PENICILLIN G; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SERINE; THREONINE; TICARCILLIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BINDING SITE; BLA KPC 2 GENE; BLA TEM 1 GENE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENTEROBACTER CLOACAE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; FRANCE; KLUYVERA CRYOCRESCENS; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

AGED; BASE SEQUENCE; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BETA-LACTAMS; CATALYTIC DOMAIN; CEPHALOSPORIN RESISTANCE; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; DNA, BACTERIAL; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FRANCE; GENES, BACTERIAL; HUMANS; IMIPENEM; KINETICS; MALE; MODELS, MOLECULAR; MUTATION;

EID: 54049149405     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00163-08     Document Type: Article

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