Production of KPC-2 carbapenemase by an Escherichia coli clinical isolate belonging to the international ST131 clone

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 10, 2011, Pages 4935-4936

  Morris, Dearbháile ^a   Boyle, Fiona ^a   Ludden, Catherine ^a   Condon, Iris ^b   Hale, James ^c   O'Connell, Nuala ^b   Power, Lorraine ^b   Boo, Teck Wee ^a   Dhanji, Hiran ^d   Lavallee, Christian ^d   Woodford, Neil ^d   Cormican, Martin ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b UNIVERSITY HOSPITAL LIMERICK   (Ireland)

^c UNIVERSITY COLLEGE CORK   (Ireland)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; BETA LACTAMASE CTX M; CARBAPENEMASE; CEFIXIME; CEFOTAXIME; CEFOXITIN; CEFPODOXIME; CEFTAZIDIME; CEFUROXIME; CHLORAMPHENICOL; CIPROFLOXACIN; ERTAPENEM; GENTAMICIN; IMIPENEM; KANAMYCIN; MEROPENEM; MINOCYCLINE; NALIDIXIC ACID; OFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM; STREPTOMYCIN; TETRACYCLINE; TRIMETHOPRIM;

AGAR DILUTION; ANTIBIOTIC RESISTANCE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CLONE; DISK DIFFUSION; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ENTEROBACTERIACEAE; HUMAN; KLEBSIELLA PNEUMONIAE; LETTER; LOWER RESPIRATORY TRACT INFECTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; URINARY TRACT INFECTION; UROPATHOGENIC ESCHERICHIA COLI;

AGED, 80 AND OVER; BACTERIAL PROTEINS; BETA-LACTAMASES; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS;

EID: 80052837386     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.05127-11     Document Type: Letter

References (14)

1. Anonymous. 2011. Carbapenemase-producing Enterobacteriaceae in the UK, 2003-2011. Health Prot. Rep. 5:24. http://www.hpa.org.uk/hpr/archives/2011/ news2411.htm#crbpnmses.
2. Bush, K. 2010. Alarming beta-lactamase-mediated resistance in multidrugresistant Enterobacteriaceae. Curr. Opin. Microbiol. 13:558-564.
3. Clermont, O., et al. 2009. Rapid detection of the O25b-ST131 clone of Escherichia coli encompassing the CTX-M-15-producing strains. J. Antimicrob. Chemother. 64:274-277.
4. Clinical Laboratory Standards Institute. 2010. Performance standards for antimicrobial disk susceptibility tests; approved standard, 20th informational supplement. CLSI document M100-S20. CLSI, Wayne, PA.
5. Cuzon, G., et al. 2010. Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene. Emerg. Infect. Dis. 16:1349-1356.
6. Essack, S. Y., L. M. Hall, D. G. Pillay, M. L. McFadyen, and D. M. Livermore. 2001. Complexity and diversity of Klebsiella pneumoniae strains with extended-spectrum beta-lactamases isolated in 1994 and 1996 at a teaching hospital in Durban, South Africa. Antimicrob. Agents Chemother. 45:88-95. (Pubitemid 32039099)
7. Giakkoupi, P., et al. 2011. An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10). J. Antimicrob. Chemother. 66:1510-1513.
8. Kitchel, B., et al. 2009. Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258. Antimicrob. Agents Chemother. 53:3365-3370.
9. Mantengoli, E., et al. 2011. Escherichia coli ST131 producing extendedspectrum beta-lactamases plus VIM-1 carbapenemase: further narrowing of treatment options. Clin. Infect. Dis. 52:690-691.
10. Peirano, G., P. C. Schreckenberger, and J. D. Pitout. 2011. The characteristics of NDM-1-producing Escherichia coli that belong to the successful and virulent clone ST131. Antimicrob. Agents Chemother. 55:2986-2988.
11. Poirel, L., C. Hombrouck-Alet, C. Freneaux, S. Bernabeu, and P. Nordmann. 2010. Global spread of New Delhi metallo-beta-lactamase 1. Lancet Infect. Dis. 10:832.
12. Rogers, B. A., H. E. Sidjabat, and D. L. Paterson. 2011. Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain. J. Antimicrob. Chemother. 66:1-14.
13. Woodford, N., E. J. Fagan, and M. J. Ellington. 2006. Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases. J. Antimicrob. Chemother. 57:154-155.
14. Woodford, N., et al. 2004. Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center. Antimicrob. Agents Chemother. 48:4793-4799.