Field cancerization in sporadic colon cancer

Gut and Liver

Volumn 10, Issue 5, 2016, Pages 773-780

  Park, Soo Kyung ^a,b   Song, Chang Seok ^a,b   Yang, Hyo Joon ^a,b   Jung, Yoon Suk ^a,b   Choi, Kyu Yong ^a,b   Koo, Dong Hoe ^a,b   Kim, Kyung Eun ^b   Jeong, Kyung Uk ^b   Kim, Hyung Ook ^b   Kim, Hungdai ^b   Chun, Ho Kyung ^b   Park, Dong Il ^a,b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b School of Medicine   (South Korea)

Author keywords

Colorectal neoplasms; DNA methylation; Epigenomics; Field effect

Indexed keywords

DNA; MEMBRANE PROTEIN; N MYC DOWNSTREAM REGULATED GENE 4 PROTEIN; OSTEOGENIN; PLACENTA PROTEIN 5; SECRETED FRIZZLED RELATED PROTEIN 2; UNCLASSIFIED DRUG; BMPR2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; GLYCOPROTEIN; MUSCLE PROTEIN; NDRG4 PROTEIN, HUMAN; NERVE PROTEIN; SFRP2 PROTEIN, HUMAN; TISSUE-FACTOR-PATHWAY INHIBITOR 2; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER TISSUE; CLINICAL ARTICLE; COLON CANCER; COLONOSCOPY; CONTROLLED STUDY; DNA ISOLATION; DNA METHYLATION; FEMALE; FIELD CANCERIZATION; HUMAN; HUMAN TISSUE; MALE; ONCOLOGICAL PARAMETERS; POLYMERASE CHAIN REACTION; PROMOTER REGION; VERY ELDERLY; CASE CONTROL STUDY; COLON; COLON TUMOR; GENETICS; INTESTINE MUCOSA; MIDDLE AGED; PATHOLOGY;

BIOMARKERS, TUMOR; BONE MORPHOGENETIC PROTEIN 3; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CASE-CONTROL STUDIES; COLON; COLONIC NEOPLASMS; COLONOSCOPY; DNA METHYLATION; FEMALE; GLYCOPROTEINS; HUMANS; INTESTINAL MUCOSA; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC;

EID: 84990064121     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl15334     Document Type: Article

References (31)

1. Markowitz SD, Bertagnolli MM. Molecular origins of cancer: molecular basis of colorectal cancer. N Engl J Med 2009;361:2449-2460.
2. Kim ER, Kim YH. Clinical application of genetics in management of colorectal cancer. Intest Res 2014;12:184-193.
3. Baylin SB, Ohm JE. Epigenetic gene silencing in cancer: a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006;6:107-116.
4. Goel A, Boland CR. Epigenetics of colorectal cancer. Gastroenterology 2012;143:1442-1460.e1.
5. Kim MS, Lee J, Sidransky D. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev 2010;29:181-206.
6. Kondo Y, Issa JP. Epigenetic changes in colorectal cancer. Cancer Metastasis Rev 2004;23:29-39.
7. Zou H, Harrington JJ, Shire AM, et al. Highly methylated genes in colorectal neoplasia: implications for screening. Cancer Epidemiol Biomarkers Prev 2007;16:2686-2696.
8. Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium: clinical implications of multicentric origin. Cancer 1953;6:963-968.
9. Luo Y, Yu M, Grady WM. Field cancerization in the colon: a role for aberrant DNA methylation? Gastroenterol Rep (Oxf) 2014;2: 16-20.
10. Bernstein C, Bernstein H, Payne CM, Dvorak K, Garewal H. Field defects in progression to gastrointestinal tract cancers. Cancer Lett 2008;260:1-10.
11. Turenne CY, Tschetter L, Wolfe J, Kabani A. Necessity of qualitycontrolled 16S rRNA gene sequence databases: identifying nontuberculous Mycobacterium species. J Clin Microbiol 2001;39:3637-3648.
12. Shen L, Kondo Y, Rosner GL, et al. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst 2005;97:1330-1338.
13. Van Assche G, Dignass A, Bokemeyer B, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations. J Crohns Colitis 2013;7: 1-33.
14. Levi F, Randimbison L, Blanc-Moya R, et al. High constant incidence of second primary colorectal cancer. Int J Cancer 2013;132:1679-1682.
15. Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004;10:789-799.
16. Worthley DL, Whitehall VL, Buttenshaw RL, et al. DNA methylation within the normal colorectal mucosa is associated with pathway- specific predisposition to cancer. Oncogene 2010;29:1653-1662.
17. Grady WM, Parkin RK, Mitchell PS, et al. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene 2008;27:3880-3888.
18. Suzuki H, Gabrielson E, Chen W, et al. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 2002;31:141-149.
19. Suzuki H, Watkins DN, Jair KW, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004;36:417-422.
20. Sui C, Wang G, Chen Q, Ma J. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol 2014;35:10457-10465.
21. Hibi K, Goto T, Kitamura YH, et al. Methylation of TFPI2 gene is frequently detected in advanced well-differentiated colorectal cancer. Anticancer Res 2010;30:1205-1207.
22. Melotte V, Lentjes MH, van den Bosch SM, et al. N-Myc downstream- regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer. J Natl Cancer Inst 2009;101:916-927.
23. Loh K, Chia JA, Greco S, et al. Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development. Genes Chromosomes Cancer 2008;47:449-460.
24. Ahlquist DA, Zou H, Domanico M, et al. Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. Gastroenterology 2012;142:248-256.
25. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med 2014;370:1287-1297.
26. Fodde R, Smits R, Clevers H. APC, signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 2001;1:55-67.
27. Xu Q, D'Amore PA, Sokol SY. Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist. Development 1998;125:4767-4776.
28. Wong CM, Ng YL, Lee JM, et al. Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. Hepatology 2007;45:1129-1138.
29. Sato N, Parker AR, Fukushima N, et al. Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma. Oncogene 2005;24: 850-858.
30. Zhou RH, Kokame K, Tsukamoto Y, Yutani C, Kato H, Miyata T. Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Genomics 2001;73:86-97.
31. Koinuma K, Kaneda R, Toyota M, et al. Screening for genomic fragments that are methylated specifically in colorectal carcinoma with a methylated MLH1 promoter. Carcinogenesis 2005;26:2078-2085.