-
1
-
-
84880346637
-
Breast cancer as a systemic disease: a view of metastasis
-
[1] Redig, A.J., McAllister, S.S., Breast cancer as a systemic disease: a view of metastasis. J. Intern Med. 274 (2013), 113–126.
-
(2013)
J. Intern Med.
, vol.274
, pp. 113-126
-
-
Redig, A.J.1
McAllister, S.S.2
-
2
-
-
24944561382
-
Essential role for Ras signaling in glioblastoma maintenance
-
[2] Holmen, S.L., Williams, B.O., Essential role for Ras signaling in glioblastoma maintenance. Cancer Res. 65 (2005), 8250–8255.
-
(2005)
Cancer Res.
, vol.65
, pp. 8250-8255
-
-
Holmen, S.L.1
Williams, B.O.2
-
3
-
-
34547100321
-
RAS/RAF pathway activation in gliomas: the result of copy number gains rather than activating mutations
-
[3] Jeuken, J., van den Broecke, C., Gijsen, S., Boots-Sprenger, S., Wesseling, P., RAS/RAF pathway activation in gliomas: the result of copy number gains rather than activating mutations. Acta Neuropathol. 114 (2007), 121–133.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 121-133
-
-
Jeuken, J.1
van den Broecke, C.2
Gijsen, S.3
Boots-Sprenger, S.4
Wesseling, P.5
-
4
-
-
33846205171
-
Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration
-
[4] Goldberg, L., Kloog, Y.A., Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration. Cancer Res. 66 (2006), 11709–11717.
-
(2006)
Cancer Res.
, vol.66
, pp. 11709-11717
-
-
Goldberg, L.1
Kloog, Y.A.2
-
5
-
-
34748821802
-
The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion
-
[5] Hjelmeland, A.B., Lattimore, K.P., Fee, B.E., Shi, Q., Wickman, S., Keir, S.T., Hjelmeland, M.D., et al. The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion. Mol. Cancer Ther. 6 (2007), 2449–2457.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 2449-2457
-
-
Hjelmeland, A.B.1
Lattimore, K.P.2
Fee, B.E.3
Shi, Q.4
Wickman, S.5
Keir, S.T.6
Hjelmeland, M.D.7
-
6
-
-
54349109317
-
Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target
-
[6] Zeng, L., Imamoto, A., Rosner, M.R., Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target. Expert Opin. Ther. Targets 12 (2008), 1275–1287.
-
(2008)
Expert Opin. Ther. Targets
, vol.12
, pp. 1275-1287
-
-
Zeng, L.1
Imamoto, A.2
Rosner, M.R.3
-
7
-
-
41849102400
-
Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor
-
[7] Granovsky, A.E., Rosner, M.R., Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Cell Res. 18 (2008), 452–457.
-
(2008)
Cell Res.
, vol.18
, pp. 452-457
-
-
Granovsky, A.E.1
Rosner, M.R.2
-
8
-
-
36248980460
-
Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction
-
[8] Klysik, J., Theroux, S.J., Sedivy, J.M., Moffit, J.S., Boekelheide, K., Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cell Signal 20 (2008), 1–9.
-
(2008)
Cell Signal
, vol.20
, pp. 1-9
-
-
Klysik, J.1
Theroux, S.J.2
Sedivy, J.M.3
Moffit, J.S.4
Boekelheide, K.5
-
9
-
-
84903901117
-
RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2
-
[9] Sun, M., Gomes, S., Chen, P., Frankenberger, C.A., Sankarasharma, D., Chung, C.H., Chada, K.K., et al. RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2. Oncogene 33 (2014), 3528–3537.
-
(2014)
Oncogene
, vol.33
, pp. 3528-3537
-
-
Sun, M.1
Gomes, S.2
Chen, P.3
Frankenberger, C.A.4
Sankarasharma, D.5
Chung, C.H.6
Chada, K.K.7
-
10
-
-
80455174648
-
Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer
-
[10] Yun, J., Frankenberger, C.A., Kuo, W.L., Boelens, M.C., Eves, E.M., Cheng, N., Liang, H., et al. Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J. 30 (2011), 4500–4514.
-
(2011)
EMBO J.
, vol.30
, pp. 4500-4514
-
-
Yun, J.1
Frankenberger, C.A.2
Kuo, W.L.3
Boelens, M.C.4
Eves, E.M.5
Cheng, N.6
Liang, H.7
-
11
-
-
33846941188
-
High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma
-
[11] Hebert, C., Norris, K., Scheper, M.A., Nikitakis, N., Sauk, J.J., High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma. Mol. Cancer, 6, 2007, 5.
-
(2007)
Mol. Cancer
, vol.6
, pp. 5
-
-
Hebert, C.1
Norris, K.2
Scheper, M.A.3
Nikitakis, N.4
Sauk, J.J.5
-
12
-
-
42249103794
-
Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family
-
[12] Motoyama, K., Inoue, H., Nakamura, Y., Uetake, H., Sugihara, K., Mori, M., Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. Clin. Cancer Res. 14 (2008), 2334–2340.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 2334-2340
-
-
Motoyama, K.1
Inoue, H.2
Nakamura, Y.3
Uetake, H.4
Sugihara, K.5
Mori, M.6
-
13
-
-
58149148165
-
HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma
-
[13] Hristov, A.C., Cope, L., Reyes, M.D., Singh, M., Iacobuzio-Donahue, C., Maitra, A., Resar, L.M., HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma. Mod. Pathol. 22 (2009), 43–49.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 43-49
-
-
Hristov, A.C.1
Cope, L.2
Reyes, M.D.3
Singh, M.4
Iacobuzio-Donahue, C.5
Maitra, A.6
Resar, L.M.7
-
14
-
-
34447532061
-
HMGA2 overexpression in non-small cell lung cancer
-
[14] Meyer, B., Loeschke, S., Schultze, A., Weigel, T., Sandkamp, M., Goldmann, T., Vollmer, E., et al. HMGA2 overexpression in non-small cell lung cancer. Mol. Carcinog. 46 (2007), 503–511.
-
(2007)
Mol. Carcinog.
, vol.46
, pp. 503-511
-
-
Meyer, B.1
Loeschke, S.2
Schultze, A.3
Weigel, T.4
Sandkamp, M.5
Goldmann, T.6
Vollmer, E.7
-
15
-
-
43049117843
-
HMGA2 mRNA expression correlates with the malignant phenotype in human thyroid neoplasias
-
[15] Chiappetta, G., Ferraro, A., Vuttariello, E., Monaco, M., Galdiero, F., De Simone, V., Califano, D., et al. HMGA2 mRNA expression correlates with the malignant phenotype in human thyroid neoplasias. Eur. J. Cancer 44 (2008), 1015–1021.
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 1015-1021
-
-
Chiappetta, G.1
Ferraro, A.2
Vuttariello, E.3
Monaco, M.4
Galdiero, F.5
De Simone, V.6
Califano, D.7
-
16
-
-
1542720383
-
Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity
-
[16] Miyazawa, J., Mitoro, A., Kawashiri, S., Chada, K.K., Imai, K., Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res. 64 (2004), 2024–2029.
-
(2004)
Cancer Res.
, vol.64
, pp. 2024-2029
-
-
Miyazawa, J.1
Mitoro, A.2
Kawashiri, S.3
Chada, K.K.4
Imai, K.5
-
17
-
-
44949237000
-
HMGA2 gene is a promising target for ovarian cancer silencing therapy
-
[17] Malek, A., Bakhidze, E., Noske, A., Sers, C., Aigner, A., Schafer, R., Tchernitsa, O., HMGA2 gene is a promising target for ovarian cancer silencing therapy. Int. J. Cancer 123 (2008), 348–356.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 348-356
-
-
Malek, A.1
Bakhidze, E.2
Noske, A.3
Sers, C.4
Aigner, A.5
Schafer, R.6
Tchernitsa, O.7
-
18
-
-
84925283559
-
RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OPN
-
[18] Liu, H., Li, P., Li, B., Sun, P., Zhang, J., Wang, B., Jia, B., RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OPN. Tumour Biol. 35 (2014), 11949–11958.
-
(2014)
Tumour Biol.
, vol.35
, pp. 11949-11958
-
-
Liu, H.1
Li, P.2
Li, B.3
Sun, P.4
Zhang, J.5
Wang, B.6
Jia, B.7
-
19
-
-
85013269757
-
Raf kinase inhibitor protein (RKIP) inhibits the cell migration and invasion in human glioma cell lines in vitro
-
[19] Lei, X., Chang, L., Ye, W., Jiang, C., Zhang, Z., Raf kinase inhibitor protein (RKIP) inhibits the cell migration and invasion in human glioma cell lines in vitro. Int. J. Clin. Exp. Pathol. 8 (2015), 14214–14220.
-
(2015)
Int. J. Clin. Exp. Pathol.
, vol.8
, pp. 14214-14220
-
-
Lei, X.1
Chang, L.2
Ye, W.3
Jiang, C.4
Zhang, Z.5
-
20
-
-
84893774245
-
Overexpression of RKIP inhibits cell invasion in glioma cell lines through upregulation of miR-98
-
[20] Chen, Z., Cheng, Q., Ma, Z., Xi, H., Peng, R., Jiang, B., Overexpression of RKIP inhibits cell invasion in glioma cell lines through upregulation of miR-98. Biomed. Res. Int., 2013, 2013, 695179.
-
(2013)
Biomed. Res. Int.
, vol.2013
, pp. 695179
-
-
Chen, Z.1
Cheng, Q.2
Ma, Z.3
Xi, H.4
Peng, R.5
Jiang, B.6
-
21
-
-
84975318173
-
The biological complexity of RKIP signaling in human cancers
-
[21] Farooqi, A.A., Li, Y., Sarkar, F.H., The biological complexity of RKIP signaling in human cancers. Exp. Mol. Med., 47, 2015, e185.
-
(2015)
Exp. Mol. Med.
, vol.47
, pp. e185
-
-
Farooqi, A.A.1
Li, Y.2
Sarkar, F.H.3
-
22
-
-
60549104367
-
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
-
[22] Dangi-Garimella, S., Yun, J., Eves, E.M., Newman, M., Erkeland, S.J., Hammond, S.M., Minn, A.J., et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J. 28 (2009), 347–358.
-
(2009)
EMBO J.
, vol.28
, pp. 347-358
-
-
Dangi-Garimella, S.1
Yun, J.2
Eves, E.M.3
Newman, M.4
Erkeland, S.J.5
Hammond, S.M.6
Minn, A.J.7
-
23
-
-
34948892058
-
Diffuse glioma growth: a guerilla war
-
[23] Claes, A., Idema, A.J., Wesseling, P., Diffuse glioma growth: a guerilla war. Acta Neuropathol. 114 (2007), 443–458.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 443-458
-
-
Claes, A.1
Idema, A.J.2
Wesseling, P.3
-
24
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
[24] Louis, D.N., Ohgaki, H., Wiestler, O.D., Cavenee, W.K., Burger, P.C., Jouvet, A., Scheithauer, B.W., et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114 (2007), 97–109.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
-
25
-
-
48249125791
-
Malignant gliomas in adults
-
[25] Wen, P.Y., Kesari, S., Malignant gliomas in adults. N. Engl. J. Med. 359 (2008), 492–507.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
26
-
-
84870668442
-
The role of microRNAs in breast cancer migration, invasion and metastasis
-
[26] Tang, J., Ahmad, A., Sarkar, F.H., The role of microRNAs in breast cancer migration, invasion and metastasis. Int. J. Mol. Sci. 13 (2012), 13414–13437.
-
(2012)
Int. J. Mol. Sci.
, vol.13
, pp. 13414-13437
-
-
Tang, J.1
Ahmad, A.2
Sarkar, F.H.3
-
27
-
-
78649265598
-
Loss of Raf-1 kinase inhibitory protein in pancreatic ductal adenocarcinoma
-
[27] Kim, H.S., Kim, G.Y., Lim, S.J., Kim, Y.W., Loss of Raf-1 kinase inhibitory protein in pancreatic ductal adenocarcinoma. Pathology 42 (2010), 655–660.
-
(2010)
Pathology
, vol.42
, pp. 655-660
-
-
Kim, H.S.1
Kim, G.Y.2
Lim, S.J.3
Kim, Y.W.4
-
28
-
-
77957359351
-
PEBP1 downregulation is associated to poor prognosis in HCC related to hepatitis B infection
-
[28] Xu, Y.F., Yi, Y., Qiu, S.J., Gao, Q., Li, Y.W., Dai, C.X., Cai, M.Y., et al. PEBP1 downregulation is associated to poor prognosis in HCC related to hepatitis B infection. J. Hepatol. 53 (2010), 872–879.
-
(2010)
J. Hepatol.
, vol.53
, pp. 872-879
-
-
Xu, Y.F.1
Yi, Y.2
Qiu, S.J.3
Gao, Q.4
Li, Y.W.5
Dai, C.X.6
Cai, M.Y.7
-
29
-
-
49649114120
-
Inverse association between Raf Kinase Inhibitory Protein and signal transducers and activators of transcription 3 expression in gastric adenocarcinoma patients: implications for clinical outcome
-
[29] Chatterjee, D., Sabo, E., Tavares, R., Resnick, M.B., Inverse association between Raf Kinase Inhibitory Protein and signal transducers and activators of transcription 3 expression in gastric adenocarcinoma patients: implications for clinical outcome. Clin. Cancer Res. 14 (2008), 2994–3001.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 2994-3001
-
-
Chatterjee, D.1
Sabo, E.2
Tavares, R.3
Resnick, M.B.4
-
30
-
-
70349285960
-
Loss of RKIP expression is associated with poor survival in GISTs
-
[30] Martinho, O., Gouveia, A., Silva, P., Pimenta, A., Reis, R.M., Lopes, J.M., Loss of RKIP expression is associated with poor survival in GISTs. Virchows Arch. 455 (2009), 277–284.
-
(2009)
Virchows Arch.
, vol.455
, pp. 277-284
-
-
Martinho, O.1
Gouveia, A.2
Silva, P.3
Pimenta, A.4
Reis, R.M.5
Lopes, J.M.6
-
31
-
-
84921325331
-
RKIP suppresses gastric cancer cell proliferation and invasion and enhances apoptosis regulated by microRNA-224
-
[31] Liu, H., Li, P., Li, B., Sun, P., Zhang, J., Wang, B., Jia, B., RKIP suppresses gastric cancer cell proliferation and invasion and enhances apoptosis regulated by microRNA-224. Tumour Biol. 35 (2014), 10095–10103.
-
(2014)
Tumour Biol.
, vol.35
, pp. 10095-10103
-
-
Liu, H.1
Li, P.2
Li, B.3
Sun, P.4
Zhang, J.5
Wang, B.6
Jia, B.7
-
32
-
-
79957552560
-
Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98
-
[32] Alajez, N.M., Shi, W., Hui, A.B., Bruce, J., Lenarduzzi, M., Ito, E., Yue, S., et al. Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. Cell Death Dis., 1, 2010, e85.
-
(2010)
Cell Death Dis.
, vol.1
, pp. e85
-
-
Alajez, N.M.1
Shi, W.2
Hui, A.B.3
Bruce, J.4
Lenarduzzi, M.5
Ito, E.6
Yue, S.7
-
33
-
-
85013339889
-
MiR-185 acts as a tumor suppressor by targeting AKT1 in non-small cell lung cancer cells
-
[33] Li, S., Ma, Y., Hou, X., Liu, Y., Li, K., Xu, S., Wang, J., MiR-185 acts as a tumor suppressor by targeting AKT1 in non-small cell lung cancer cells. Int. J. Clin. Exp. Pathol. 8 (2015), 11854–11862.
-
(2015)
Int. J. Clin. Exp. Pathol.
, vol.8
, pp. 11854-11862
-
-
Li, S.1
Ma, Y.2
Hou, X.3
Liu, Y.4
Li, K.5
Xu, S.6
Wang, J.7
-
34
-
-
84918561270
-
miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer
-
[34] Tang, H., Liu, P., Yang, L., Xie, X., Ye, F., Wu, M., Liu, X., et al. miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer. Mol. Cancer Ther. 13 (2014), 3185–3197.
-
(2014)
Mol. Cancer Ther.
, vol.13
, pp. 3185-3197
-
-
Tang, H.1
Liu, P.2
Yang, L.3
Xie, X.4
Ye, F.5
Wu, M.6
Liu, X.7
-
35
-
-
84891555541
-
miR-185 is an independent prognosis factor and suppresses tumor metastasis in gastric cancer
-
[35] Tan, Z., Jiang, H., Wu, Y., Xie, L., Dai, W., Tang, H., Tang, S., miR-185 is an independent prognosis factor and suppresses tumor metastasis in gastric cancer. Mol. Cell Biochem. 386 (2014), 223–231.
-
(2014)
Mol. Cell Biochem.
, vol.386
, pp. 223-231
-
-
Tan, Z.1
Jiang, H.2
Wu, Y.3
Xie, L.4
Dai, W.5
Tang, H.6
Tang, S.7
-
36
-
-
84946214504
-
Plasma miR-185 is decreased in patients with esophageal squamous cell carcinoma and might suppress tumor migration and invasion by targeting RAGE
-
[36] Jing, R., Chen, W., Wang, H., Ju, S., Cong, H., Sun, B., Jin, Q., et al. Plasma miR-185 is decreased in patients with esophageal squamous cell carcinoma and might suppress tumor migration and invasion by targeting RAGE. Am. J. Physiol. Gastrointest. Liver Physiol. 309 (2015), G719–G729.
-
(2015)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.309
, pp. G719-G729
-
-
Jing, R.1
Chen, W.2
Wang, H.3
Ju, S.4
Cong, H.5
Sun, B.6
Jin, Q.7
-
37
-
-
3442883359
-
Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines
-
[37] Schuierer, M.M., Bataille, F., Hagan, S., Kolch, W., Bosserhoff, A.K., Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res. 64 (2004), 5186–5192.
-
(2004)
Cancer Res.
, vol.64
, pp. 5186-5192
-
-
Schuierer, M.M.1
Bataille, F.2
Hagan, S.3
Kolch, W.4
Bosserhoff, A.K.5
-
38
-
-
0038275924
-
Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis
-
[38] Fu, Z., Smith, P.C., Zhang, L., Rubin, M.A., Dunn, R.L., Yao, Z., Keller, E.T., Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J. Natl. Cancer Inst. 95 (2003), 878–889.
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 878-889
-
-
Fu, Z.1
Smith, P.C.2
Zhang, L.3
Rubin, M.A.4
Dunn, R.L.5
Yao, Z.6
Keller, E.T.7
|