Combined systemic elimination of MET and epidermal growth factor receptor signaling completely abolishes liver regeneration and leads to liver decompensation

Hepatology

Volumn 64, Issue 5, 2016, Pages 1711-1724

  Paranjpe, Shirish ^a   Bowen, William C ^a   Mars, Wendy M ^a   Orr, Anne ^a   Haynes, Meagan M ^a   DeFrances, Marie C ^a   Liu, Silvia ^b   Tseng, George C ^b   Tsagianni, Anastasia ^a   Michalopoulos, George K ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; AMMONIA; CANERTINIB; CAT PROTEIN; CCS PROTEIN; CYCLIN D1; CYTOCHROME P450; EPIDERMAL GROWTH FACTOR RECEPTOR; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 1; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 4; GCLC PROTEIN; GCLM PROTEIN; GLUTAMATE AMMONIA LIGASE; HEMOPEXIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ORNITHINE CARBAMOYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN; PROTEIN KINASE B; PROTEIN P21; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; THIOREDOXIN INTERACTING PROTEIN; TRANSFERRIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AMMONIA BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCITES; BODY WEIGHT; CELL PROLIFERATION; CELL SIZE; CELL VOLUME; CITRIC ACID CYCLE; COMPARATIVE STUDY; CONTROLLED STUDY; DECOMPENSATED LIVER CIRRHOSIS; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; GENE EXPRESSION; GLYCOLYSIS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIPID METABOLISM; LIPID STORAGE; LIVER LOBULE; LIVER REGENERATION; LIVER RESECTION; LIVER WEIGHT; MALE; MICROPHOTOGRAPHY; MOUSE; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; TUNEL ASSAY; UPREGULATION; UREA CYCLE; ANIMAL; LIVER FAILURE; PHYSIOLOGY;

ANIMALS; LIVER FAILURE; LIVER REGENERATION; MALE; MICE; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84990047813     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28721     Document Type: Article

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