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Volumn 21, Issue 12, 2016, Pages 1663-1671

Caspr2-reactive antibody cloned from a mother of an ASD child mediates an ASD-like phenotype in mice

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CONTACTIN ASSOCIATED PROTEIN LIKE 2 ANTIBODY; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; PARVALBUMIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; ANTIBODY; CNTNAP2 PROTEIN, HUMAN; COMPLEMENT COMPONENT C6; MEMBRANE PROTEIN; NERVE PROTEIN;

EID: 84989957030     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2016.165     Document Type: Article
Times cited : (78)

References (51)
  • 2
    • 84900527418 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorder among children aged 8 years -autism and developmental disabilities monitoring network, 11 sites, United States, 2010
    • Developmental Disabilities Monitoring Network Surveillance Year 2010 Principal Investigators; Centers for Disease Control and Prevention (CDC
    • Developmental Disabilities Monitoring Network Surveillance Year 2010 Principal Investigators; Centers for Disease Control and Prevention (CDC). Prevalence of autism spectrum disorder among children aged 8 years -autism and developmental disabilities monitoring network, 11 sites, United States, 2010. MMWR Surveill Summ 2014; 63: 1-21
    • (2014) MMWR Surveill Summ , vol.63 , pp. 1-21
  • 3
    • 84910150637 scopus 로고    scopus 로고
    • Familial recurrence of autism spectrum disorder: Evaluating genetic and environmental contributions
    • Risch N, Hoffmann TJ, Anderson M, Croen LA, Grether JK, Windham GC. Familial recurrence of autism spectrum disorder: evaluating genetic and environmental contributions. Am J Psychiatry 2014; 171: 1206-1213
    • (2014) Am J Psychiatry , vol.171 , pp. 1206-1213
    • Risch, N.1    Hoffmann, T.J.2    Anderson, M.3    Croen, L.A.4    Grether, J.K.5    Windham, G.C.6
  • 4
    • 84857192192 scopus 로고    scopus 로고
    • Maternal infection and autism
    • Patterson PH. Maternal infection and autism. Brain Behav Immun 2012; 26: 393
    • (2012) Brain Behav Immun , vol.26 , pp. 393
    • Patterson, P.H.1
  • 5
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith SE, Li J, Garbett K, Mirnics K, Patterson PH. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci 2007; 27: 10695-10702
    • (2007) J Neurosci , vol.27 , pp. 10695-10702
    • Smith, S.E.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 6
    • 84959447961 scopus 로고    scopus 로고
    • The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
    • Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, et al. The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science 2016; 351: 933-939
    • (2016) Science , vol.351 , pp. 933-939
    • Choi, G.B.1    Yim, Y.S.2    Wong, H.3    Kim, S.4    Kim, H.5    Kim, S.V.6
  • 7
    • 84870499875 scopus 로고    scopus 로고
    • Autism after infection, febrile episodes, and antibiotic use during pregnancy: An exploratory study
    • Atladottir HO, Henriksen TB, Schendel DE, Parner ET. Autism after infection, febrile episodes, and antibiotic use during pregnancy: an exploratory study. Pediatrics 2012; 130: e1447-e1454
    • (2012) Pediatrics , vol.130 , pp. e1447-e1454
    • Atladottir, H.O.1    Henriksen, T.B.2    Schendel, D.E.3    Parner, E.T.4
  • 8
    • 84923218412 scopus 로고    scopus 로고
    • Epigenetics of autism-related impairment: Copy number variation and maternal infection
    • Mazina V, Gerdts J, Trinh S, Ankenman K, Ward T, Dennis MY, et al. Epigenetics of autism-related impairment: copy number variation and maternal infection. J Dev Behav Pediatr 2015; 36: 61-67
    • (2015) J Dev Behav Pediatr , vol.36 , pp. 61-67
    • Mazina, V.1    Gerdts, J.2    Trinh, S.3    Ankenman, K.4    Ward, T.5    Dennis, M.Y.6
  • 9
    • 84888286336 scopus 로고    scopus 로고
    • Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder
    • Brimberg L, Sadiq A, Gregersen PK, Diamond B. Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder. Mol Psychiatry 2013; 18: 1171-1177
    • (2013) Mol Psychiatry , vol.18 , pp. 1171-1177
    • Brimberg, L.1    Sadiq, A.2    Gregersen, P.K.3    Diamond, B.4
  • 13
    • 0344687381 scopus 로고    scopus 로고
    • Maternal neuronal antibodies associated with autism and a language disorder
    • Dalton P, Deacon R, Blamire A, Pike M, McKinlay I, Stein J, et al. Maternal neuronal antibodies associated with autism and a language disorder. Ann Neurol 2003; 53: 533-537
    • (2003) Ann Neurol , vol.53 , pp. 533-537
    • Dalton, P.1    Deacon, R.2    Blamire, A.3    Pike, M.4    McKinlay, I.5    Stein, J.6
  • 15
    • 84880166349 scopus 로고    scopus 로고
    • Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey
    • Bauman MD, Iosif AM, Ashwood P, Braunschweig D, Lee A, Schumann CM, et al. Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey. Transl Psychiatry 2013; 3: e278
    • (2013) Transl Psychiatry , vol.3 , pp. e278
    • Bauman, M.D.1    Iosif, A.M.2    Ashwood, P.3    Braunschweig, D.4    Lee, A.5    Schumann, C.M.6
  • 16
    • 67349116508 scopus 로고    scopus 로고
    • Prenatal exposure to antibodies from mothers of children with autism produces neurobehavioral alterations: A pregnant dam mouse model
    • Singer HS, Morris C, Gause C, Pollard M, Zimmerman AW, Pletnikov M. Prenatal exposure to antibodies from mothers of children with autism produces neurobehavioral alterations: a pregnant dam mouse model. J Neuroimmunol 2009; 211: 39-48
    • (2009) J Neuroimmunol , vol.211 , pp. 39-48
    • Singer, H.S.1    Morris, C.2    Gause, C.3    Pollard, M.4    Zimmerman, A.W.5    Pletnikov, M.6
  • 19
    • 0033396331 scopus 로고    scopus 로고
    • Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels
    • Poliak S, Gollan L, Martinez R, Custer A, Einheber S, Salzer JL, et al. Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels. Neuron 1999; 24: 1037-1047
    • (1999) Neuron , vol.24 , pp. 1037-1047
    • Poliak, S.1    Gollan, L.2    Martinez, R.3    Custer, A.4    Einheber, S.5    Salzer, J.L.6
  • 20
    • 80053540965 scopus 로고    scopus 로고
    • Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits
    • Penagarikano O, Abrahams BS, Herman EI, Winden KD, Gdalyahu A, Dong H, et al. Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. Cell 2011; 147: 235-246
    • (2011) Cell , vol.147 , pp. 235-246
    • Penagarikano, O.1    Abrahams, B.S.2    Herman, E.I.3    Winden, K.D.4    Gdalyahu, A.5    Dong, H.6
  • 21
    • 77957927440 scopus 로고    scopus 로고
    • The simons simplex collection: A resource for identification of autism genetic risk factors
    • Fischbach GD, Lord C. The Simons Simplex Collection: a resource for identification of autism genetic risk factors. Neuron 2010; 68: 192-195
    • (2010) Neuron , vol.68 , pp. 192-195
    • Fischbach, G.D.1    Lord, C.2
  • 22
    • 50949118232 scopus 로고    scopus 로고
    • Identification of DNA-reactive B cells in patients with systemic lupus erythematosus
    • Zhang J, Jacobi AM, Mackay M, Aranow C, Wang T, Chinnasamy P, et al. Identification of DNA-reactive B cells in patients with systemic lupus erythematosus. J Immunol Methods 2008; 338: 79-84
    • (2008) J Immunol Methods , vol.338 , pp. 79-84
    • Zhang, J.1    Jacobi, A.M.2    MacKay, M.3    Aranow, C.4    Wang, T.5    Chinnasamy, P.6
  • 23
    • 36849031722 scopus 로고    scopus 로고
    • Efficient generation of monoclonal antibodies from single human B cells by single cell RTPCR and expression vector cloning
    • Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H. Efficient generation of monoclonal antibodies from single human B cells by single cell RTPCR and expression vector cloning. J Immunol Methods 2008; 329: 112-124
    • (2008) J Immunol Methods , vol.329 , pp. 112-124
    • Tiller, T.1    Meffre, E.2    Yurasov, S.3    Tsuiji, M.4    Nussenzweig, M.C.5    Wardemann, H.6
  • 24
    • 58149344949 scopus 로고    scopus 로고
    • Neurotoxic autoantibodies mediate congenital cortical impairment qof offspring in maternal lupus
    • Lee JY, Huerta PT, Zhang J, Kowal C, Bertini E, Volpe BT, et al. Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus. Nat Med 2009; 15: 91-96
    • (2009) Nat Med , vol.15 , pp. 91-96
    • Lee, J.Y.1    Huerta, P.T.2    Zhang, J.3    Kowal, C.4    Bertini, E.5    Volpe, B.T.6
  • 26
    • 72949114659 scopus 로고    scopus 로고
    • Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo
    • Bradl M, Misu T, Takahashi T, Watanabe M, Mader S, Reindl M, et al. Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo. Ann Neurol 2009; 66: 630-643
    • (2009) Ann Neurol , vol.66 , pp. 630-643
    • Bradl, M.1    Misu, T.2    Takahashi, T.3    Watanabe, M.4    Mader, S.5    Reindl, M.6
  • 27
  • 28
    • 84868121906 scopus 로고    scopus 로고
    • Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
    • Anderson GR, Galfin T, Xu W, Aoto J, Malenka RC, Sudhof TC. Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development. Proc Natl Acad Sci USA 2012; 109: 18120-18125
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 18120-18125
    • Anderson, G.R.1    Galfin, T.2    Xu, W.3    Aoto, J.4    Malenka, R.C.5    Sudhof, T.C.6
  • 30
    • 0141433266 scopus 로고    scopus 로고
    • Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1
    • Poliak S, Salomon D, Elhanany H, Sabanay H, Kiernan B, Pevny L, et al. Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1. J Cell Biol 2003; 162: 1149-1160
    • (2003) J Cell Biol , vol.162 , pp. 1149-1160
    • Poliak, S.1    Salomon, D.2    Elhanany, H.3    Sabanay, H.4    Kiernan, B.5    Pevny, L.6
  • 31
    • 84929353630 scopus 로고    scopus 로고
    • The autism related protein contactin-associated protein-like 2 (CNTNAP2) stabilizes new spines: An in vivo mouse study
    • Gdalyahu A, Lazaro M, Penagarikano O, Golshani P, Trachtenberg JT, Geschwind DH. The autism related protein contactin-associated protein-like 2 (CNTNAP2) stabilizes new spines: an in vivo mouse study. PLoS One 2015; 10: e0125633
    • (2015) Plos One , vol.10 , pp. e0125633
    • Gdalyahu, A.1    Lazaro, M.2    Penagarikano, O.3    Golshani, P.4    Trachtenberg, J.T.5    Geschwind, D.H.6
  • 32
    • 38749140677 scopus 로고    scopus 로고
    • Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene
    • Alarcon M, Abrahams BS, Stone JL, Duvall JA, Perederiy JV, Bomar JM, et al. Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. Am J Hum Genet 2008; 82: 150-159
    • (2008) Am J Hum Genet , vol.82 , pp. 150-159
    • Alarcon, M.1    Abrahams, B.S.2    Stone, J.L.3    Duvall, J.A.4    Perederiy, J.V.5    Bomar, J.M.6
  • 33
    • 84867837982 scopus 로고    scopus 로고
    • Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation
    • Falivelli G, De Jaco A, Favaloro FL, Kim H, Wilson J, Dubi N, et al. Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation. Hum Mol Genet 2012; 21: 4761-4773
    • (2012) Hum Mol Genet , vol.21 , pp. 4761-4773
    • Falivelli, G.1    De Jaco, A.2    Favaloro, F.L.3    Kim, H.4    Wilson, J.5    Dubi, N.6
  • 34
    • 0038278610 scopus 로고    scopus 로고
    • CNTNAP2 is disrupted in a family with gilles de la tourette syndrome and obsessive compulsive disorder
    • Verkerk AJ, Mathews CA, Joosse M, Eussen BH, Heutink P, Oostra BA. CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder. Genomics 2003; 82: 1-9
    • (2003) Genomics , vol.82 , pp. 1-9
    • Verkerk, A.J.1    Mathews, C.A.2    Joosse, M.3    Eussen, B.H.4    Heutink, P.5    Oostra, B.A.6
  • 35
    • 0038384134 scopus 로고    scopus 로고
    • Placental transport of immunoglobulin G
    • Simister NE. Placental transport of immunoglobulin G. Vaccine 2003; 21: 3365-3369
    • (2003) Vaccine , vol.21 , pp. 3365-3369
    • Simister, N.E.1
  • 36
    • 84898468206 scopus 로고    scopus 로고
    • The effects of early-life seizures on hippocampal dendrite development and later-life learning and memory
    • Casanova JR, Nishimura M, Swann JW. The effects of early-life seizures on hippocampal dendrite development and later-life learning and memory. Brain Res Bull 2014; 103: 39-48
    • (2014) Brain Res Bull , vol.103 , pp. 39-48
    • Casanova, J.R.1    Nishimura, M.2    Swann, J.W.3
  • 38
  • 40
    • 33947681627 scopus 로고    scopus 로고
    • Digging and marble burying in mice: Simple methods for in vivo identification of biological impacts
    • Deacon RM. Digging and marble burying in mice: simple methods for in vivo identification of biological impacts. Nat Protoc 2006; 1: 122-124
    • (2006) Nat Protoc , vol.1 , pp. 122-124
    • Deacon, R.M.1
  • 41
    • 67349201064 scopus 로고    scopus 로고
    • Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety
    • Thomas A, Burant A, Bui N, Graham D, Yuva-Paylor LA, Paylor R. Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety. Psychopharmacology (Berl) 2009; 204: 361-373
    • (2009) Psychopharmacology (Berl , vol.204 , pp. 361-373
    • Thomas, A.1    Burant, A.2    Bui, N.3    Graham, D.4    Yuva-Paylor, L.A.5    Paylor, R.6
  • 42
    • 84947489051 scopus 로고    scopus 로고
    • Selective impairment of spatial cognition caused by autoantibodies to the N-methyl-daspartate receptor
    • Chang EH, Volpe BT, Mackay M, Aranow C, Watson P, Kowal C, et al. Selective impairment of spatial cognition caused by autoantibodies to the N-methyl-daspartate receptor. EBioMed 2015; 2: 755-764
    • (2015) EBioMed , vol.2 , pp. 755-764
    • Chang, E.H.1    Volpe, B.T.2    MacKay, M.3    Aranow, C.4    Watson, P.5    Kowal, C.6
  • 43
    • 77956225035 scopus 로고    scopus 로고
    • Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2
    • Tan GC, Doke TF, Ashburner J, Wood NW, Frackowiak RS. Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2. Neuroimage 2010; 53: 1030-1042
    • (2010) Neuroimage , vol.53 , pp. 1030-1042
    • Tan, G.C.1    Doke, T.F.2    Ashburner, J.3    Wood, N.W.4    Frackowiak, R.S.5
  • 44
    • 70449517234 scopus 로고    scopus 로고
    • The anterior cingulate cortex in autism: Heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups
    • Simms ML, Kemper TL, Timbie CM, Bauman ML, Blatt GJ. The anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups. Acta Neuropathol 2009; 118: 673-684
    • (2009) Acta Neuropathol , vol.118 , pp. 673-684
    • Simms, M.L.1    Kemper, T.L.2    Timbie, C.M.3    Bauman, M.L.4    Blatt, G.J.5
  • 45
    • 0035203309 scopus 로고    scopus 로고
    • The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system
    • Denaxa M, Chan CH, Schachner M, Parnavelas JG, Karagogeos D. The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system. Development 2001; 128: 4635-4644
    • (2001) Development , vol.128 , pp. 4635-4644
    • Denaxa, M.1    Chan, C.H.2    Schachner, M.3    Parnavelas, J.G.4    Karagogeos, D.5
  • 46
    • 0025237057 scopus 로고
    • The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity
    • Furley AJ, Morton SB, Manalo D, Karagogeos D, Dodd J, Jessell TM. The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity. Cell 1990; 61: 157-170
    • (1990) Cell , vol.61 , pp. 157-170
    • Furley, A.J.1    Morton, S.B.2    Manalo, D.3    Karagogeos, D.4    Dodd, J.5    Jessell, T.M.6
  • 47
    • 0033962732 scopus 로고    scopus 로고
    • Long-term memory underlying hippocampusdependent social recognition in mice
    • Kogan JH, Frankland PW, Silva AJ. Long-term memory underlying hippocampusdependent social recognition in mice. Hippocampus 2000; 10: 47-56
    • (2000) Hippocampus , vol.10 , pp. 47-56
    • Kogan, J.H.1    Frankland, P.W.2    Silva, A.J.3
  • 49
    • 84958212452 scopus 로고    scopus 로고
    • Estrogens suppress a behavioral phenotype in zebrafish mutants of the autism risk gene, CNTNAP2
    • Hoffman EJ, Turner KJ, Fernandez JM, Cifuentes D, Ghosh M, Ijaz S, et al. Estrogens suppress a behavioral phenotype in zebrafish mutants of the autism risk gene, CNTNAP2. Neuron 2016; 89: 725-733
    • (2016) Neuron , vol.89 , pp. 725-733
    • Hoffman, E.J.1    Turner, K.J.2    Fernandez, J.M.3    Cifuentes, D.4    Ghosh, M.5    Ijaz, S.6
  • 51
    • 77956378343 scopus 로고    scopus 로고
    • Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, morvan's syndrome and acquired neuromyotonia
    • Irani SR, Alexander S, Waters P, Kleopa KA, Pettingill P, Zuliani L, et al. Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia. Brain 2010; 133: 2734-2748
    • (2010) Brain , vol.133 , pp. 2734-2748
    • Irani, S.R.1    Alexander, S.2    Waters, P.3    Kleopa, K.A.4    Pettingill, P.5    Zuliani, L.6


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