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Volumn 141, Issue , 2016, Pages S40-S45

Factor XI and factor XII as targets for new anticoagulants

Author keywords

Anticoagulants; contact system; factor XI; factor XII; intrinsic pathway; thrombosis

Indexed keywords

ANTICOAGULANT AGENT; ANTISENSE OLIGONUCLEOTIDE; APTAMER; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; ENOXAPARIN; ANTIBODY; MOLECULAR LIBRARY;

EID: 84989930205     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/S0049-3848(16)30363-2     Document Type: Article
Times cited : (67)

References (47)
  • 2
    • 84896741977 scopus 로고    scopus 로고
    • Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: a systematic review and meta-analysis
    • 2 van der Hulle, T, Kooiman, J, den Exter, PL, Dekkers, OM, Klok, FA, Huisman, MV, Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: a systematic review and meta-analysis. J. Thromb. Haemost. 12 (2014), 320–328.
    • (2014) J. Thromb. Haemost. , vol.12 , pp. 320-328
    • van der Hulle, T.1    Kooiman, J.2    den Exter, P.L.3    Dekkers, O.M.4    Klok, F.A.5    Huisman, M.V.6
  • 3
    • 80051794851 scopus 로고    scopus 로고
    • Factor XI and XII as antithrombotic targets
    • 3 Müller, F, Gailani, D, Renné, T, Factor XI and XII as antithrombotic targets. Curr. Opin. Hematol. 18 (2011), 349–355.
    • (2011) Curr. Opin. Hematol. , vol.18 , pp. 349-355
    • Müller, F.1    Gailani, D.2    Renné, T.3
  • 4
    • 84937974660 scopus 로고    scopus 로고
    • Factor XI and contact activation as targets for antithombotic therapy
    • 4 Gailani, D, Bane, E, Gruber, A, Factor XI and contact activation as targets for antithombotic therapy. J. Thromb. Haemost. 13 (2015), 1383–1395.
    • (2015) J. Thromb. Haemost. , vol.13 , pp. 1383-1395
    • Gailani, D.1    Bane, E.2    Gruber, A.3
  • 5
    • 79851476826 scopus 로고    scopus 로고
    • Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis
    • 5 Salomon, O, Steinberg, DM, Zucker, M, Varon, D, Zivelin, A, Seligsohn, U, Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis. Thromb. Haemost. 105 (2011), 269–273.
    • (2011) Thromb. Haemost. , vol.105 , pp. 269-273
    • Salomon, O.1    Steinberg, D.M.2    Zucker, M.3    Varon, D.4    Zivelin, A.5    Seligsohn, U.6
  • 6
    • 43249088304 scopus 로고    scopus 로고
    • Reduced incidence of ischemic stroke in patients with severe factor XI deficiency
    • 6 Salomon, O, Steinberg, DM, Koren-Morag, N, Tanne, D, Seligsohn, U, Reduced incidence of ischemic stroke in patients with severe factor XI deficiency. Blood 111 (2008), 4113–4117.
    • (2008) Blood , vol.111 , pp. 4113-4117
    • Salomon, O.1    Steinberg, D.M.2    Koren-Morag, N.3    Tanne, D.4    Seligsohn, U.5
  • 9
    • 84906097265 scopus 로고    scopus 로고
    • Polyphosphate; a new player in the field of hemostasis
    • 9 Smith, SA, Morrissey, JH, Polyphosphate; a new player in the field of hemostasis. Curr. Opin Hematol 21 (2014), 388–394.
    • (2014) Curr. Opin Hematol , vol.21 , pp. 388-394
    • Smith, S.A.1    Morrissey, J.H.2
  • 12
    • 84906940224 scopus 로고    scopus 로고
    • Neutrophil extracellular traps promote thrombin generation through platelet-dependent and platelet-independent mechanisms
    • 12 Gould, TJ, Vu, TT, Swystun, LL, Dwivedi, DJ, Mai, SH, Weitz, JI, Liaw, PC, Neutrophil extracellular traps promote thrombin generation through platelet-dependent and platelet-independent mechanisms. Arterioscler. Thromb. Vasc. Biol. 34 (2014), 1977–1984.
    • (2014) Arterioscler. Thromb. Vasc. Biol. , vol.34 , pp. 1977-1984
    • Gould, T.J.1    Vu, T.T.2    Swystun, L.L.3    Dwivedi, D.J.4    Mai, S.H.5    Weitz, J.I.6    Liaw, P.C.7
  • 13
    • 67849097372 scopus 로고    scopus 로고
    • Factor XI deficiency in humans
    • 13 Seligsohn, U, Factor XI deficiency in humans. J. Thromb. Hemost. 7 (2009), 84–87.
    • (2009) J. Thromb. Hemost. , vol.7 , pp. 84-87
    • Seligsohn, U.1
  • 14
    • 84859707412 scopus 로고    scopus 로고
    • The procoagulant and proinflammatory plasma contact system
    • 14 Renne, T, The procoagulant and proinflammatory plasma contact system. Semin. Immunopathol. 34 (2012), 31–41.
    • (2012) Semin. Immunopathol. , vol.34 , pp. 31-41
    • Renne, T.1
  • 15
    • 84898978532 scopus 로고    scopus 로고
    • Physiologic activities of the contact activation system
    • 15 Schmaier, AH, Physiologic activities of the contact activation system. Thromb. Res. 133 (2014), S41–S44.
    • (2014) Thromb. Res. , vol.133 , pp. S41-S44
    • Schmaier, A.H.1
  • 16
    • 84255201932 scopus 로고    scopus 로고
    • Polyphosphate is a cofactor for the activation of factor XI by thrombin
    • 16 Choi, SH, Smith, SA, Morrissey, JH, Polyphosphate is a cofactor for the activation of factor XI by thrombin. Blood 118 (2011), 6963–6970.
    • (2011) Blood , vol.118 , pp. 6963-6970
    • Choi, S.H.1    Smith, S.A.2    Morrissey, J.H.3
  • 17
    • 84951304886 scopus 로고    scopus 로고
    • Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic pathway of coagulation
    • Epub ahead of print.
    • 17 Vu, TT, Leslie, BA, Stafford, AR, Zhou, J, Fredenburgh, JC, Weitz, JI, Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic pathway of coagulation. Thromb. Haemost., 115, 2015 Epub ahead of print.
    • (2015) Thromb. Haemost. , vol.115
    • Vu, T.T.1    Leslie, B.A.2    Stafford, A.R.3    Zhou, J.4    Fredenburgh, J.C.5    Weitz, J.I.6
  • 19
    • 70449472262 scopus 로고    scopus 로고
    • Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology
    • 19 Cushman, M, O'Meara, ES, Folsom, AR, Heckbert, SR, Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology. Blood 114 (2009), 2878–2883.
    • (2009) Blood , vol.114 , pp. 2878-2883
    • Cushman, M.1    O'Meara, E.S.2    Folsom, A.R.3    Heckbert, S.R.4
  • 20
    • 78349308080 scopus 로고    scopus 로고
    • Intrinsic coagulation activation and the risk of arterial thrombosis in young women: results from the Risk of Arterial Thrombosis in relation to Oral contraceptives (RATIO) case-control study
    • 20 Siegerink, B, Govers-Riemslag, JW, Rosendaal, FR, Ten Cate, H, Algra, A, Intrinsic coagulation activation and the risk of arterial thrombosis in young women: results from the Risk of Arterial Thrombosis in relation to Oral contraceptives (RATIO) case-control study. Circulation 122 (2010), 1854–1861.
    • (2010) Circulation , vol.122 , pp. 1854-1861
    • Siegerink, B.1    Govers-Riemslag, J.W.2    Rosendaal, F.R.3    Ten Cate, H.4    Algra, A.5
  • 21
    • 33845497457 scopus 로고    scopus 로고
    • Levels of instrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII
    • 21 Doggen, CJ, Rosendaal, FR, Meijers, JC, Levels of instrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII. Blood 108 (2006), 4045–4051.
    • (2006) Blood , vol.108 , pp. 4045-4051
    • Doggen, C.J.1    Rosendaal, F.R.2    Meijers, J.C.3
  • 23
    • 0028234054 scopus 로고
    • John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia Study
    • 23 Koster, T, Rosendaal, FR, Briet, E, Vandenbroucke, JP, John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia Study. Br. J. Haematol. 87 (1994), 422–424.
    • (1994) Br. J. Haematol. , vol.87 , pp. 422-424
    • Koster, T.1    Rosendaal, F.R.2    Briet, E.3    Vandenbroucke, J.P.4
  • 24
    • 0032825571 scopus 로고    scopus 로고
    • Reevaluation of the incidence of thromboembolic complications in congenital factor XII deficiency – a study on 73 subjects from 14 Swiss families
    • 24 Zeerleder, S, Schloesser, M, Redondo, M, Wuillemin, WA, Engel, W, Furlan, M, Lammle, B, Reevaluation of the incidence of thromboembolic complications in congenital factor XII deficiency – a study on 73 subjects from 14 Swiss families. Thromb. Haemost. 82 (1999), 1240–1246.
    • (1999) Thromb. Haemost. , vol.82 , pp. 1240-1246
    • Zeerleder, S.1    Schloesser, M.2    Redondo, M.3    Wuillemin, W.A.4    Engel, W.5    Furlan, M.6    Lammle, B.7
  • 28
    • 84897552463 scopus 로고    scopus 로고
    • Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits
    • 28 Yau, JW, Liao, P, Fredenburgh, JC, Stafford, AR, Revenko, AS, Monia, BP, Weitz, JI, Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits. Blood 123 (2014), 2102–2107.
    • (2014) Blood , vol.123 , pp. 2102-2107
    • Yau, J.W.1    Liao, P.2    Fredenburgh, J.C.3    Stafford, A.R.4    Revenko, A.S.5    Monia, B.P.6    Weitz, J.I.7
  • 31
    • 84880447362 scopus 로고    scopus 로고
    • Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer
    • 31 Woodruff, RS, Xu, Y, Layzer, J, Wu, W, Ogletree, ML, Sullenger, BA, Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer. J. Thromb. Haemost. 11 (2013), 1364–1373.
    • (2013) J. Thromb. Haemost. , vol.11 , pp. 1364-1373
    • Woodruff, R.S.1    Xu, Y.2    Layzer, J.3    Wu, W.4    Ogletree, M.L.5    Sullenger, B.A.6
  • 33
    • 80052467986 scopus 로고    scopus 로고
    • A small-molecule factor XIa inhibitor produces antithrombotic efficacy with minimal bleeding time prolongation in rabbits
    • 33 Wong, PC, Crain, EJ, Watson, CA, Schumacher, WA, A small-molecule factor XIa inhibitor produces antithrombotic efficacy with minimal bleeding time prolongation in rabbits. J. Thromb. Thrombolysis 32 (2011), 129–137.
    • (2011) J. Thromb. Thrombolysis , vol.32 , pp. 129-137
    • Wong, P.C.1    Crain, E.J.2    Watson, C.A.3    Schumacher, W.A.4
  • 35
    • 84873898236 scopus 로고    scopus 로고
    • Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa
    • 35 Al-Horani, RA, Ponnusamy, P, Mehta, AY, Gailani, D, Desai, UR, Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa. J. Med. Chem. 56 (2013), 867–878.
    • (2013) J. Med. Chem. , vol.56 , pp. 867-878
    • Al-Horani, R.A.1    Ponnusamy, P.2    Mehta, A.Y.3    Gailani, D.4    Desai, U.R.5
  • 36
    • 84902438454 scopus 로고    scopus 로고
    • Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides
    • 36 Al-Horani, RA, Desai, UR, Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides. J. Med. Chem. 57 (2014), 4805–4818.
    • (2014) J. Med. Chem. , vol.57 , pp. 4805-4818
    • Al-Horani, R.A.1    Desai, U.R.2
  • 37
    • 0025874052 scopus 로고    scopus 로고
    • Factor XI activation in a revised model of blood coagulation
    • 37 Gailani, D, Broze, GJ Jr, Factor XI activation in a revised model of blood coagulation. Science 253 (1999), 909–912.
    • (1999) Science , vol.253 , pp. 909-912
    • Gailani, D.1    Broze, G.J.2
  • 38
    • 84931327017 scopus 로고    scopus 로고
    • Medical device-induced thrombosis: what causes it and how can we prevent it?
    • 38 Jaffer, IH, Fredenburgh, JC, Hirsh, J, Weitz, JI, Medical device-induced thrombosis: what causes it and how can we prevent it?. J. Thromb. Haemost. 13 (2015), S72–S81.
    • (2015) J. Thromb. Haemost. , vol.13 , pp. S72-S81
    • Jaffer, I.H.1    Fredenburgh, J.C.2    Hirsh, J.3    Weitz, J.I.4
  • 39
    • 84873973841 scopus 로고    scopus 로고
    • Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo
    • 39 Yau, JW, Stafford, AR, Liao, P, Fredenburgh, JC, Roberts, R, Brash, JL, Weitz, JI, Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo. Acta Biomater 8 (2012), 4092–4100.
    • (2012) Acta Biomater , vol.8 , pp. 4092-4100
    • Yau, J.W.1    Stafford, A.R.2    Liao, P.3    Fredenburgh, J.C.4    Roberts, R.5    Brash, J.L.6    Weitz, J.I.7
  • 42
    • 84879117604 scopus 로고    scopus 로고
    • Rx, a novel and specific antisense inhibitor of factor XI, caused a significant reduction in FXI antigen and activity and increased aPTT without causing bleeding in healthy volunteers
    • Abst.#209.
    • Rx, a novel and specific antisense inhibitor of factor XI, caused a significant reduction in FXI antigen and activity and increased aPTT without causing bleeding in healthy volunteers. Blood, 118, 2011 Abst.#209.
    • (2011) Blood , vol.118
    • Liu, Q.1    Bethune, C.2    Dessouki, E.3    Gundy, J.4    Monia, B.P.5    Bhanot, S.6
  • 44
    • 0037704209 scopus 로고    scopus 로고
    • Natural history of venous thromboembolism
    • 44 Kearon, C, Natural history of venous thromboembolism. Circulation 107 (2003), I22–I30.
    • (2003) Circulation , vol.107 , pp. I22-I30
    • Kearon, C.1
  • 47
    • 84908554196 scopus 로고    scopus 로고
    • Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome
    • 47 Weitz, JI, Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome. Thromb Haemost 112 (2014), 924–931.
    • (2014) Thromb Haemost , vol.112 , pp. 924-931
    • Weitz, J.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.