Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation

Journal of the American Heart Association

Volumn 4, Issue 8, 2015, Pages e002322-

  Jaffer, Iqbal H ^a   Stafford, Alan R ^a   Fredenburgh, James C ^a   Whitlock, Richard P ^a   Chan, Noel C ^a   Weitz, Jeffrey I ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

anticoagulants; coagulation; thrombin; valves

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN; DABIGATRAN; THROMBIN; WARFARIN;

ADVERSE EFFECTS; BLEEDING; BLOOD; CHEMICALLY INDUCED; COMPARATIVE STUDY; DEVICES; DOSE RESPONSE; HEART VALVE PROSTHESIS; HEART VALVE REPLACEMENT; HUMAN; INTERNATIONAL NORMALIZED RATIO; KINETICS; METABOLISM; PROSTHESIS DESIGN; THROMBOEMBOLISM; TREATMENT OUTCOME;

ANTICOAGULANTS; ANTITHROMBINS; DABIGATRAN; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART VALVE PROSTHESIS; HEART VALVE PROSTHESIS IMPLANTATION; HEMORRHAGE; HUMANS; INTERNATIONAL NORMALIZED RATIO; KINETICS; PROSTHESIS DESIGN; THROMBIN; THROMBOEMBOLISM; TREATMENT OUTCOME; WARFARIN;

EID: 84968453686     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.002322     Document Type: Article

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