R-Phycoerythrin induces SGC-7901 apoptosis by arresting cell cycle at S Phase

Marine Drugs

Volumn 14, Issue 9, 2016, Pages

  Tan, Huixin ^a   Gao, Shiyong ^b   Zhuang, Yan ^b   Dong, Yanhong ^a   Guan, Wenhui ^a   Zhang, Kun ^a   Xu, Jian ^a   Cui, Jingru ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN UNIVERSITY OF COMMERCE   (China)

Author keywords

Apoptosis; Cell cycle arrest; Cell cycle related protein; Human gastric cancer; R phycoerythrin

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE 2; PHYCOERYTHRIN; PROTEIN CDC25A; PROTEIN TYROSINE PHOSPHATASE; R PHYCOERYTHRIN; UNCLASSIFIED DRUG; CDC25A PROTEIN, HUMAN; CDK2 PROTEIN, HUMAN; CELL CYCLE PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; ENZYME ACTIVATION; GASTRIC CANCER CELL LINE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IC50; MITOSIS INHIBITION; PROTEIN PROTEIN INTERACTION; S PHASE CELL CYCLE CHECKPOINT; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CYCLE CHECKPOINT; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENETICS; TUMOR CELL LINE;

APOPTOSIS; CDC25 PHOSPHATASES; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN A; CYCLIN-DEPENDENT KINASE 2; HUMANS; PHYCOERYTHRIN; S PHASE;

EID: 84989920994     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md14090166     Document Type: Article

References (37)

1. Zhao, M.R.; Sun, L.; Sun, S.C.; Gong, X.Q.; Fu, X.J.; Chen, M. The 42.1 and 53.7 kDa bands in SDS-PAGE of R-phycoerythrin from Polysiphonia urceolata. Int. J. Biol. Macromol. 2013, 60, 405-411. [CrossRef] [PubMed]
2. Manirafasha, E.; Ndikubwimana, T.; Zeng, X.H.; Lu, Y.H.; Jing, K.J. Phycobiliprotein: Potential microalgae derived pharmaceutical and biological reagent. Biochem. Eng. J. 2016, 109, 282-296. [CrossRef]
3. Galland-Irmouli, A.V.; Pons, L.; Lucon, M.; Villaume, C.; Mrabet, N.T.; Gueant, J.L.; Fleurence, J. One-step purification of R-phycoerythrin from the red macroalga Palmaria palmata using preparative polyacrylamide gel electrophoresis. J. Chromatogr. B Biomed. Sci. Appl. 2000, 739, 117-123. [CrossRef]
4. Stadnichuk, I.N. Phycobiliproteins-determination of chromophore composition and content. Phytochem. Anal. 1995, 6, 281-288. [CrossRef]
5. Wang, L.; Wang, S.M.; Fu, X.J.; Sun, L. Characteristics of an R-phycoerythrin with two gamma subunits prepared from red macroalga Polysiphonia urceolata. PLoS ONE 2015, 10, e0120333.
6. Wilson, K.M.; Morrison, I.E.G.; Smith, P.R.; Fernandez, N.; Cherry, R.J. Single particle tracking of cell-surface HLA-DR molecules using R-phycoerythrin labeled monoclonal antibodies and fluorescence digital imaging. J. Cell Sci. 1996, 109, 2101-2109. [PubMed]
7. Bradford, J.A.; Buller, G.; Suter, M.; Ignatius, M.; Beechem, J.M. Fluorescence-intensity multiplexing: Simultaneous seven-marker, two-color immunophenotyping using flow cytometry. Cytometry A 2004, 61, 142-152. [CrossRef] [PubMed]
8. Selva, C.; Malferrari, M.; Ballardini, R.; Ventola, A.; Francia, F.; Venturoli, G. Trehalose preserves the integrity of lyophilized phycoerythrin-antihuman CD8 antibody conjugates and enhances their thermal stability in flow cytometric assays. J. Pharm. Sci. 2013, 102, 649-659. [CrossRef] [PubMed]
9. Kim, M.S.; Kim, T.S. R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells. Cytometry A 2013, 83, 452-460. [CrossRef] [PubMed]
10. Hilditch, C.M.; Balding, P.; Jenkins, R.; Smith, A.J.; Rogers, L.J. R-Phycoerythrin from the macroalga corallina-officinalis (rhodophyceae) and application of a derived phycofluor probe for detecting sugar-binding sites on cell-membranes. J. Appl. Phycol. 1991, 3, 345-354. [CrossRef]
11. Zhang, F.; Li, J.F.; Zou, M.Q.; Chen, Y.; Wang, Y.F.; Qi, X.H. Simultaneous Detection of Clavibacter michiganensis subsp nebraskensis and Pantoea stewartii subsp. stewartii based on microsphere immunoreaction. J. Biomol. Screen. 2013, 18, 474-480. [CrossRef] [PubMed]
12. Munier, M.; Jubeau, S.; Wijaya, A.; Morancais, M.; Dumay, J.; Marchal, L.; Jaouen, P.; Fleurence, J. Physicochemical factors affecting the stability of two pigments: R-Phycoerythrin of Grateloupia turuturu and B-phycoerythrin of Porphyridium cruentum. Food Chem. 2014, 150, 400-407. [CrossRef] [PubMed]
13. Huang, B.; Wang, G.C.; Zeng, C.K.; Li, Z.G. The experimental research of R-phycoerythrin subunits on cancer treatment: A new photosensitizer in PDT. Cancer Biother. Radiopharm. 2002, 17, 35-42. [PubMed]
14. Wu, Q.; Fu, X.P.; Sun, L.C.; Zhang, Q.; Liu, G.M.; Cao, M.J.; Cai, Q.F. Effects of physicochemical factors and in vitro gastrointestinal digestion on antioxidant activity of R-phycoerythrin from red algae Bangia fusco-purpurea. Int. J. Food Sci. Technol. 2015, 50, 1445-1451. [CrossRef]
15. Senthilkumar, N.; Kurinjimalar, C.; Thangam, R.; Suresh, V.; Kavitha, G.; Gunasekaran, P.; Rengasamy, R. Further studies and biological activities of macromolecular protein R-phycoerythrin from Portieria homemannii. Int. J. Biol. Macromol. 2013, 62, 107-116. [CrossRef] [PubMed]
16. Pan, Q.W.; Chen, M.Z.; Li, J.; Wu, Y.; Zhen, C.; Liang, B. Antitumor function and mechanism of phycoerythrin from Porphyra haitanensis. Biol. Res. 2013, 46, 87-95. [CrossRef] [PubMed]
17. Sonani, R.R.; Singh, N.K.; Awasthi, A.; Prasad, B.; Kumar, J.; Madamwar, D. Phycoerythrin extends life span and health span of Caenorhabditis elegans. Age 2014, 36, 1-14. [CrossRef] [PubMed]
18. Daniel, B.; DeCoster, M.A. Quantification of sPLA2-induced early and late apoptosis changes in neuronal cell cultures using combined TUNEL and DAPI staining. Brain Res. 2004, 13, 144-450. [CrossRef] [PubMed]
19. Marcellus, R.C.; Lavoie, J.N.; Boivin, D.; Shore, G.C.; Ketner, G.; Branton, P.E. The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis. J. Virol. 1998, 72, 7144-7153. [PubMed]
20. Jia, S.G.; Wang, X.M.; Qian, H.; Li, T.Y.; Sun, J.; Wang, L.; Yu, J.; Li, X.G.; Yin, J.L.; Liu, T.; et al. Phylogenomic analysis of transcriptomic sequences of mitochondria and chloroplasts for marine red algae (Rhodophyta) in China. Acta Oceanol. Sin. 2014, 33, 86-93. [CrossRef]
21. Thomas, D. Seaweeds; The Natural History Museum: London, UK, 2002.
22. Sukhoverkhov, S.V.; Kadnikova, I.A.; Podkorytova, A.V. Preparation of agar and agarose from the red algae Ahnfeltia tobuchiensis. Prikl. Biokhim. Mikrobiol. 2000, 36, 238-240. [PubMed]
23. Ermak, I.M.; Reunov, A.V.; Lapshina, L.A.; Byankina, A.O.; Bratskaya, S.Y.; Sokolova, E.V. Physicochemical and electron-microscopic study of carrageenans, sulfated polysaccharides from red algae of the families Tichocarpaceae and Gigartinaceae. Chem. Nat. Compd. 2013, 49, 593-595. [CrossRef]
24. Murugan, K.; Iyer, V.V. Differential growth inhibition of cancer cell lines and antioxidant activity of extracts of red, brown, and green marine algae. In Vitro Cell. Dev. Biol. Anim. 2013, 49, 324-334. [CrossRef] [PubMed]
25. Zandi, K.; Tajbakhsh, S.; Nabipour, I.; Rastian, Z.; Yousefi, F.; Sharafian, S.; Sartavi, K. In vitro antitumor activity of Gracilaria corticata (a red alga) against Jurkat and molt-4 human cancer cell lines. Afr. J. Biotechnol. 2010, 9, 6787-6790.
26. Allmendinger, A.; Spavieri, J.; Kaiser, M.; Casey, R.; Hingley-Wilson, S.; Lalvani, A.; Guiry, M.; Blunden, G.; Tasdemir, D. Antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three british and irish red algae. Phytother. Res. 2010, 24, 1099-1103. [CrossRef] [PubMed]
27. Raman, M.; Doble, M. kappa-Carrageenan from marine red algae, Kappaphycus alvarezii - A functional food to prevent colon carcinogenesis. J. Funct. Foods 2015, 15, 354-364. [CrossRef]
28. Wang, X.M.; Zhang, Z.S. The antitumor activity of a red alga polysaccharide complexes carrying 5-fluorouracil. Int. J. Biol. Macromol. 2014, 69, 542-545. [CrossRef] [PubMed]
29. Kazlowska, K.; Lin, H.T.V.; Chang, S.H.; Tsai, G.J. In Vitro and In Vivo Anticancer Effects of Sterol Fraction from Red Algae Porphyra dentata. Evid. Based Complement. Altern. Med. 2013. [CrossRef]
30. Lin, A.S.; Engel, S.; Smith, B.A.; Fairchild, C.R.; Aalbersberg, W.; Hay, M.E.; Kubanek, J. Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp. Bioorg. Med. Chem. 2010, 18, 8264-8269. [CrossRef] [PubMed]
31. George Rosenker, K.M.; Paquette, W.D.; Johnston, P.A.; Sharlow, E.R.; Vogt, A.; Bakan, A.; Lazo, J.S.; Wipf, P. Synthesis and biological evaluation of 3-aminoisoquinolin-1 (2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B. Bioorg. Med. Chem. 2015, 23, 2810-2818. [CrossRef] [PubMed]
32. Tilaoui, M.; Mouse, H.A.; Jaafari, A.; Zyad, A. Differential effect of artemisinin against cancer cell lines. Nat. Prod. Bioprospect. 2014, 4, 189-196. [CrossRef] [PubMed]
33. Gao, S.Y.; Li, J.; Wang, L.; Sun, Q.J.; Gong, Y.F.; Gang, J.; Su, Y.J.; Ji, Y.B. Ethanol but not aqueous extracts of tubers of Sauromatum giganteum (Engl.) Cusimano and Hett inhibit cancer cell proliferation. Asian Pac. J. Cancer Prev. 2014, 15, 10613-10619. [CrossRef] [PubMed]
34. Gao, S.; Tan, H.; Zhu, N.; Gao, H.; Lv, C.; Gang, J.; Ji, Y. Oridonin induces apoptosis through the mitochondrial pathway in human gastric cancer SGC-7901 cells. Int. J. Oncol. 2016, 48, 2453-2460. [CrossRef] [PubMed]
35. Gao, S.Y.; Gong, Y.F.; Sun, Q.J.; Bai, J.; Wang, L.; Fan, Z.Q.; Sun, Y.; Su, Y.J.; Gang, J.; Ji, Y.B. Screening antitumor bioactive fraction from Sauromatum giganteum (Engl.) Cusimano & Hett and sensitive cell lines with the serum pharmacology method and identification by UPLC-TOF-MS. Molecules 2015, 20, 4290-4306. [PubMed]
36. Gao, S.Y.; Li, J.; Qu, X.Y.; Zhu, N.; Ji, Y.B. Downregulation of Cdk1 and Cyclin B1 Expression Contributes to Oridonin-induced Cell Cycle Arrest at G (2)/M Phase and Growth Inhibition in SGC-7901 Gastric Cancer Cells. Asian Pac. J. Cancer Prev. 2014, 15, 6437-6441. [CrossRef] [PubMed]
37. Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254. [CrossRef]