MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

Cell Reports

Volumn 17, Issue 1, 2016, Pages 179-192

  Eckersley Maslin, Mélanie A ^a   Svensson, Valentine ^b,c   Krueger, Christel ^a   Stubbs, Thomas M ^a   Giehr, Pascal ^d   Krueger, Felix ^a   Miragaia, Ricardo J ^b,c,e   Kyriakopoulos, Charalampos ^d   Berrens, Rebecca V ^a   Milagre, Inês ^a   Walter, Jörn ^d   Teichmann, Sarah A ^b,c   Reik, Wolf ^a,c  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d SAARLAND UNIVERSITY   (Germany)

^e UNIVERSITY OF MINHO   (Portugal)

Author keywords

chromatin; DNA methylation; embryonic stem cell; endogenous retrovirus; imprint; MERVL; preimplantation; reprogramming; Zscan4

Indexed keywords

DNA METHYLTRANSFERASE; CHROMATIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTOME; ZSCAN4C PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DNA REPLICATION; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; EPIGENETICS; GENE; GENE ACTIVATION; GENE REGULATORY NETWORK; GENOME ANALYSIS; GENOME IMPRINTING; INDUCED PLURIPOTENT STEM CELL; MERVL GENE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN DEPLETION; TRANSCRIPTOMICS; TRANSLATION REGULATION; UPREGULATION; VIRUS GENOME; ZSCAN4 GENE; ANIMAL; CELL CYCLE; CHEMISTRY; CHROMATIN; CYTOLOGY; DEFICIENCY; ENDOGENOUS RETROVIRUS; GENETIC EPIGENESIS; GENETICS; GENOME; METABOLISM; MOUSE EMBRYONIC STEM CELL; MULTIGENE FAMILY; SINGLE CELL ANALYSIS; TRANSCRIPTION INITIATION;

ANIMALS; CELL CYCLE; CELLULAR REPROGRAMMING; CHROMATIN; DNA METHYLATION; DNA MODIFICATION METHYLASES; ENDOGENOUS RETROVIRUSES; EPIGENESIS, GENETIC; GENOME; GENOMIC IMPRINTING; INDUCED PLURIPOTENT STEM CELLS; MICE; MOUSE EMBRYONIC STEM CELLS; MULTIGENE FAMILY; RNA, MESSENGER; SINGLE-CELL ANALYSIS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME;

EID: 84989818851     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.087     Document Type: Article

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