메뉴 건너뛰기




Volumn 73, Issue 10, 2016, Pages 2029-2039

G72 primate-specific gene: A still enigmatic element in psychiatric disorders

Author keywords

d Serine; DAOA; Molecular basis; NMDA receptors; pLG72; Schizophrenia

Indexed keywords

DEXTRO AMINO ACID OXIDASE; DEXTRO AMINO ACID OXIDASE ACTIVATOR; PLG72 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; DAOA PROTEIN, HUMAN; RECOMBINANT PROTEIN;

EID: 84989794455     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-016-2165-6     Document Type: Review
Times cited : (30)

References (64)
  • 1
    • 0037108758 scopus 로고    scopus 로고
    • Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia
    • 1:CAS:528:DC%2BD38XotVKmtrk%3D 12364586 129739
    • Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H et al (2002) Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia. Proc Natl Acad Sci USA 99:13675-13680
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13675-13680
    • Chumakov, I.1    Blumenfeld, M.2    Guerassimenko, O.3    Cavarec, L.4    Palicio, M.5    Abderrahim, H.6
  • 2
    • 85027953437 scopus 로고    scopus 로고
    • Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia
    • 1:CAS:528:DC%2BC3MXnsFKksLo%3D 21508934 3138664
    • Schultz CC, Nenadic I, Koch K, Wagner G, Roebel M, Schachtzabel C et al (2011) Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia. Neuropsychopharmacology 36:1747-1753
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1747-1753
    • Schultz, C.C.1    Nenadic, I.2    Koch, K.3    Wagner, G.4    Roebel, M.5    Schachtzabel, C.6
  • 4
    • 84856706805 scopus 로고    scopus 로고
    • Puzzling over schizophrenia: Schizophrenia as a pathway disease
    • 1:CAS:528:DC%2BC38XhvVSitLk%3D 22310687 4188922
    • Sullivan PF (2012) Puzzling over schizophrenia: schizophrenia as a pathway disease. Nat Med 18:210-212
    • (2012) Nat Med , vol.18 , pp. 210-212
    • Sullivan, P.F.1
  • 5
    • 84868094723 scopus 로고    scopus 로고
    • Structure-function relationships in human d-amino acid oxidase
    • 1:CAS:528:DC%2BC38XhsFSqtbbO 22865246
    • Sacchi S, Caldinelli L, Cappelletti P, Pollegioni L, Molla G (2012) Structure-function relationships in human d-amino acid oxidase. Amino Acids 43:1833-1850
    • (2012) Amino Acids , vol.43 , pp. 1833-1850
    • Sacchi, S.1    Caldinelli, L.2    Cappelletti, P.3    Pollegioni, L.4    Molla, G.5
  • 6
    • 77954584505 scopus 로고    scopus 로고
    • Metabolism of the neuromodulator d-serine
    • 1:CAS:528:DC%2BC3cXnslSmtbo%3D 20195697
    • Pollegioni L, Sacchi S (2010) Metabolism of the neuromodulator d-serine. Cell Mol Life Sci 67:2387-2404
    • (2010) Cell Mol Life Sci , vol.67 , pp. 2387-2404
    • Pollegioni, L.1    Sacchi, S.2
  • 7
    • 0034712857 scopus 로고    scopus 로고
    • D-serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor
    • 1:CAS:528:DC%2BD3cXivFKisrw%3D 10781100 18334
    • Mothet JP, Parent AT, Wolosker H, Brady RO Jr, Linden DJ, Ferris CD et al (2000) d-serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor. Proc Natl Acad Sci USA 97:4926-4931
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4926-4931
    • Mothet, J.P.1    Parent, A.T.2    Wolosker, H.3    Brady, R.O.4    Linden, D.J.5    Ferris, C.D.6
  • 8
    • 33646522699 scopus 로고    scopus 로고
    • Glia-derived d-serine controls NMDA receptor activity and synaptic memory
    • 1:CAS:528:DC%2BD28XltlSkt7k%3D 16713567
    • Panatier A, Theodosis DT, Mothet JP, Touquet B, Pollegioni L, Poulain DA et al (2006) Glia-derived d-serine controls NMDA receptor activity and synaptic memory. Cell 125:775-784
    • (2006) Cell , vol.125 , pp. 775-784
    • Panatier, A.1    Theodosis, D.T.2    Mothet, J.P.3    Touquet, B.4    Pollegioni, L.5    Poulain, D.A.6
  • 9
    • 84864634182 scopus 로고    scopus 로고
    • Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists
    • 1:CAS:528:DC%2BC38XhtFGrtrfK 22863013
    • Papouin T, Ladépêche L, Ruel J, Sacchi S, Labasque M, Hanini M et al (2012) Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists. Cell 150:633-646
    • (2012) Cell , vol.150 , pp. 633-646
    • Papouin, T.1    Ladépêche, L.2    Ruel, J.3    Sacchi, S.4    Labasque, M.5    Hanini, M.6
  • 10
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • 1:CAS:528:DyaK3sXntlOntw%3D%3D 8421494
    • Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 11
    • 0028356548 scopus 로고
    • Synaptic plasticity: LTP and LTD
    • 1:STN:280:DyaK2M%2FgtlKmsw%3D%3D 7919934
    • Bear MF, Malenka RC (1994) Synaptic plasticity: LTP and LTD. Curr Opin Neurobiol 4:389-399
    • (1994) Curr Opin Neurobiol , vol.4 , pp. 389-399
    • Bear, M.F.1    Malenka, R.C.2
  • 12
    • 45549098188 scopus 로고    scopus 로고
    • Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function
    • 1:CAS:528:DC%2BD1cXnt1alt78%3D 17684499
    • Kvajo M, Dhilla A, Swor DE, Karayiorgou M, Gogos JA (2008) Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function. Mol Psychiatry 13:685-696
    • (2008) Mol Psychiatry , vol.13 , pp. 685-696
    • Kvajo, M.1    Dhilla, A.2    Swor, D.E.3    Karayiorgou, M.4    Gogos, J.A.5
  • 13
    • 0037730178 scopus 로고    scopus 로고
    • Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series
    • 1:CAS:528:DC%2BD3sXjslagtbk%3D 12647258 1180266
    • Hattori E, Liu C, Badner JA, Bonner TI, Christian SL, Maheshwari M et al (2003) Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series. Am J Hum Genet 72:1131-1140
    • (2003) Am J Hum Genet , vol.72 , pp. 1131-1140
    • Hattori, E.1    Liu, C.2    Badner, J.A.3    Bonner, T.I.4    Christian, S.L.5    Maheshwari, M.6
  • 14
    • 3242755008 scopus 로고    scopus 로고
    • Is the G72/G30 locus associated with schizophrenia? Single nucleotide polymorphisms, haplotypes, and gene expression analysis
    • 1:CAS:528:DC%2BD2cXlvFyksLk%3D 15271585
    • Korostishevsky M, Kaganovich M, Cholostoy A, Ashkenazi M, Ratner Y, Dahary D et al (2004) Is the G72/G30 locus associated with schizophrenia? Single nucleotide polymorphisms, haplotypes, and gene expression analysis. Biol Psychiatry 56:169-176
    • (2004) Biol Psychiatry , vol.56 , pp. 169-176
    • Korostishevsky, M.1    Kaganovich, M.2    Cholostoy, A.3    Ashkenazi, M.4    Ratner, Y.5    Dahary, D.6
  • 15
    • 84901255969 scopus 로고    scopus 로고
    • Distinctively higher plasma G72 protein levels in patients with schizophrenia than in healthy individuals
    • 1:CAS:528:DC%2BC2cXosV2gt7s%3D 23857119
    • Lin CH, Chang HT, Chen YJ, Lin CH, Huang CH, Tun R et al (2014) Distinctively higher plasma G72 protein levels in patients with schizophrenia than in healthy individuals. Mol Psychiatry 19:636-637
    • (2014) Mol Psychiatry , vol.19 , pp. 636-637
    • Lin, C.H.1    Chang, H.T.2    Chen, Y.J.3    Lin, C.H.4    Huang, C.H.5    Tun, R.6
  • 16
    • 52049087606 scopus 로고    scopus 로고
    • PLG72 modulates intracellular d-serine levels through its interaction with d-amino acid oxidase: Effect on schizophrenia susceptibility
    • 1:CAS:528:DC%2BD1cXpt1aru70%3D 18544534
    • Sacchi S, Bernasconi M, Martineau M, Mothet JP, Ruzzene M, Pilone MS et al (2008) pLG72 modulates intracellular d-serine levels through its interaction with d-amino acid oxidase: effect on schizophrenia susceptibility. J Biol Chem 283:22244-22256
    • (2008) J Biol Chem , vol.283 , pp. 22244-22256
    • Sacchi, S.1    Bernasconi, M.2    Martineau, M.3    Mothet, J.P.4    Ruzzene, M.5    Pilone, M.S.6
  • 18
    • 84897406127 scopus 로고    scopus 로고
    • A promoter-level mammalian expression atlas
    • FANTOM Consortium and the RIKEN PMI and CLST (DGT)
    • FANTOM Consortium and the RIKEN PMI and CLST (DGT), Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ et al (2014) A promoter-level mammalian expression atlas. Nature 507:462-470
    • (2014) Nature , vol.507 , pp. 462-470
    • Forrest, A.R.1    Kawaji, H.2    Rehli, M.3    Baillie, J.K.4    De Hoon, M.J.5
  • 19
    • 84885645853 scopus 로고    scopus 로고
    • Transcriptome and genome sequencing uncovers functional variation in humans
    • 1:CAS:528:DC%2BC3sXhsVertLzN 24037378 3918453
    • Lappalainen T, Sammeth M, Friedländer MR, 't Hoen PA, Monlong J, Rivas MA et al (2013) Transcriptome and genome sequencing uncovers functional variation in humans. Nature 501:506-511
    • (2013) Nature , vol.501 , pp. 506-511
    • Lappalainen, T.1    Sammeth, M.2    Friedländer, M.R.3    'T Hoen, P.A.4    Monlong, J.5    Rivas, M.A.6
  • 21
    • 84929001104 scopus 로고    scopus 로고
    • Human genomics. the Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
    • Ardlie KG, Deluca DS, Segrè AV, Sullivan TJ, Young TR, Gelfand ET et al (2015) Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 348:648-660
    • (2015) Science , vol.348 , pp. 648-660
    • Ardlie, K.G.1    Deluca, D.S.2    Segrè, A.V.3    Sullivan, T.J.4    Young, T.R.5    Gelfand, E.T.6
  • 22
    • 32644480821 scopus 로고    scopus 로고
    • Expression in Escherichia coli and in vitro refolding of the human protein pLG72
    • 1:CAS:528:DC%2BD28XhsFyltLo%3D 16183301
    • Molla G, Bernasconi M, Sacchi S, Pilone MS, Pollegioni L (2006) Expression in Escherichia coli and in vitro refolding of the human protein pLG72. Protein Expr Purif 46:150-155
    • (2006) Protein Expr Purif , vol.46 , pp. 150-155
    • Molla, G.1    Bernasconi, M.2    Sacchi, S.3    Pilone, M.S.4    Pollegioni, L.5
  • 23
    • 34250002745 scopus 로고    scopus 로고
    • Physiological functions of d-amino acid oxidases: From yeast to humans
    • 1:CAS:528:DC%2BD2sXntVOgsrk%3D 17396222
    • Pollegioni L, Piubelli L, Sacchi S, Pilone MS, Molla G (2007) Physiological functions of d-amino acid oxidases: from yeast to humans. Cell Mol Life Sci 64:1373-1394
    • (2007) Cell Mol Life Sci , vol.64 , pp. 1373-1394
    • Pollegioni, L.1    Piubelli, L.2    Sacchi, S.3    Pilone, M.S.4    Molla, G.5
  • 24
    • 77955102371 scopus 로고    scopus 로고
    • Effect of ligand binding on human d-amino acid oxidase: Implications for the development of new drugs for schizophrenia treatment
    • 1:CAS:528:DC%2BC3cXptlarurk%3D 20521334 2923503
    • Caldinelli L, Molla G, Bracci L, Lelli B, Pileri S, Cappelletti P et al (2010) Effect of ligand binding on human d-amino acid oxidase: implications for the development of new drugs for schizophrenia treatment. Protein Sci 19:1500-1512
    • (2010) Protein Sci , vol.19 , pp. 1500-1512
    • Caldinelli, L.1    Molla, G.2    Bracci, L.3    Lelli, B.4    Pileri, S.5    Cappelletti, P.6
  • 25
    • 84922346390 scopus 로고    scopus 로고
    • Characterization of the enzymatic and structural properties of human d-aspartate oxidase and comparison with those of the rat and mouse enzymes
    • 1:CAS:528:DC%2BC2MXmt1akuro%3D 25747990
    • Katane M, Kawata T, Nakayama K, Saitoh Y, Kaneko Y, Matsuda S et al (2015) Characterization of the enzymatic and structural properties of human d-aspartate oxidase and comparison with those of the rat and mouse enzymes. Biol Pharm Bull 38:298-305
    • (2015) Biol Pharm Bull , vol.38 , pp. 298-305
    • Katane, M.1    Kawata, T.2    Nakayama, K.3    Saitoh, Y.4    Kaneko, Y.5    Matsuda, S.6
  • 26
    • 79960917257 scopus 로고    scopus 로고
    • Evidence for the interaction of d-amino acid oxidase with pLG72 in a glial cell line
    • 1:CAS:528:DC%2BC3MXpvFCgu7Y%3D 21679769
    • Sacchi S, Cappelletti P, Giovannardi S, Pollegioni L (2011) Evidence for the interaction of d-amino acid oxidase with pLG72 in a glial cell line. Mol Cell Neurosci 48:20-28
    • (2011) Mol Cell Neurosci , vol.48 , pp. 20-28
    • Sacchi, S.1    Cappelletti, P.2    Giovannardi, S.3    Pollegioni, L.4
  • 27
    • 84897042700 scopus 로고    scopus 로고
    • The degradation (by distinct pathways) of human d-amino acid oxidase and its interacting partner pLG72 - Two key proteins in d-serine catabolism in the brain
    • 1:CAS:528:DC%2BC2cXht1Onurg%3D 24237903
    • Cappelletti P, Campomenosi P, Pollegioni L, Sacchi S (2014) The degradation (by distinct pathways) of human d-amino acid oxidase and its interacting partner pLG72 - two key proteins in d-serine catabolism in the brain. FEBS J 281:708-723
    • (2014) FEBS J , vol.281 , pp. 708-723
    • Cappelletti, P.1    Campomenosi, P.2    Pollegioni, L.3    Sacchi, S.4
  • 29
    • 84946071902 scopus 로고    scopus 로고
    • Identification of pLG72-induced oxidative stress using systemic approaches
    • (Article ID 429253)
    • Wang M, Chen H-J, Zhang J, Li W, Xie X, Chang H-T (2015) Identification of pLG72-induced oxidative stress using systemic approaches. BioMed Res Int (Article ID 429253)
    • (2015) BioMed Res Int
    • Wang, M.1    Chen, H.-J.2    Zhang, J.3    Li, W.4    Xie, X.5    Chang, H.-T.6
  • 30
    • 84867419174 scopus 로고    scopus 로고
    • Identification of an N-methyl-d-aspartate receptor in isolated nervous system mitochondria
    • 1:CAS:528:DC%2BC38XhsFSgsL3O 22918829 3471715
    • Korde AS, Maragos WF (2012) Identification of an N-methyl-d-aspartate receptor in isolated nervous system mitochondria. J Biol Chem 287:35192-35200
    • (2012) J Biol Chem , vol.287 , pp. 35192-35200
    • Korde, A.S.1    Maragos, W.F.2
  • 31
    • 84893904007 scopus 로고    scopus 로고
    • A polygenic burden of rare disruptive mutations in schizophrenia
    • 1:CAS:528:DC%2BC2cXisVamurc%3D 24463508 4136494
    • Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P et al (2014) A polygenic burden of rare disruptive mutations in schizophrenia. Nature 506:185-190
    • (2014) Nature , vol.506 , pp. 185-190
    • Purcell, S.M.1    Moran, J.L.2    Fromer, M.3    Ruderfer, D.4    Solovieff, N.5    Roussos, P.6
  • 33
    • 84893678359 scopus 로고    scopus 로고
    • Expression of the G72/G30 gene in transgenic mice induces behavioral changes
    • 1:CAS:528:DC%2BC2cXhsVCnsbs%3D 23337943 3636154
    • Cheng L, Hattori E, Nakajima A, Woehrle NS, Opal MD, Zhang C et al (2014) Expression of the G72/G30 gene in transgenic mice induces behavioral changes. Mol Psychiatry 19:175-183
    • (2014) Mol Psychiatry , vol.19 , pp. 175-183
    • Cheng, L.1    Hattori, E.2    Nakajima, A.3    Woehrle, N.S.4    Opal, M.D.5    Zhang, C.6
  • 34
    • 84865543418 scopus 로고    scopus 로고
    • Myelination and oxidative stress alterations in the cerebellum of the G72/G30 transgenic schizophrenia mouse model
    • 22884423
    • Filiou MD, Teplytska L, Otte DM, Zimmer A, Turck CW (2012) Myelination and oxidative stress alterations in the cerebellum of the G72/G30 transgenic schizophrenia mouse model. J Psychiatr Res 46:1359-1365
    • (2012) J Psychiatr Res , vol.46 , pp. 1359-1365
    • Filiou, M.D.1    Teplytska, L.2    Otte, D.M.3    Zimmer, A.4    Turck, C.W.5
  • 35
    • 0041328892 scopus 로고    scopus 로고
    • Oligodendrocyte dysfunction in schizophrenia and bipolar disorder
    • 1:CAS:528:DC%2BD3sXntVGktLc%3D 13678875
    • Tkachev D, Mimmack ML, Ryan MM, Wayland M, Freeman T, Jones PB et al (2003) Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362:798-805
    • (2003) Lancet , vol.362 , pp. 798-805
    • Tkachev, D.1    Mimmack, M.L.2    Ryan, M.M.3    Wayland, M.4    Freeman, T.5    Jones, P.B.6
  • 36
    • 67649226736 scopus 로고    scopus 로고
    • Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia
    • 19110265
    • Martins-de-Souza D, Gattaz WF, Schmitt A, Maccarrone G, Hunyadi-Gulyás E, Eberlin MN et al (2009) Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia. J Psychiatr Res 43:978-986
    • (2009) J Psychiatr Res , vol.43 , pp. 978-986
    • Martins-De-Souza, D.1    Gattaz, W.F.2    Schmitt, A.3    Maccarrone, G.4    Hunyadi-Gulyás, E.5    Eberlin, M.N.6
  • 37
    • 77954977417 scopus 로고    scopus 로고
    • Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia
    • 20471030
    • Martins-de-Souza D, Maccarrone G, Wobrock T, Zerr I, Gormanns P, Reckow S et al (2010) Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. J Psychiatr Res 44:1176-1189
    • (2010) J Psychiatr Res , vol.44 , pp. 1176-1189
    • Martins-De-Souza, D.1    Maccarrone, G.2    Wobrock, T.3    Zerr, I.4    Gormanns, P.5    Reckow, S.6
  • 38
    • 84921550855 scopus 로고    scopus 로고
    • Lipidomics reveals dysfunctional glycosynapses in schizophrenia and the G72/G30 transgenic mouse
    • 25263995
    • Wood PL, Filiou MD, Otte DM, Zimmer A, Turck CW (2014) Lipidomics reveals dysfunctional glycosynapses in schizophrenia and the G72/G30 transgenic mouse. Schizophr Res 159:365-369
    • (2014) Schizophr Res , vol.159 , pp. 365-369
    • Wood, P.L.1    Filiou, M.D.2    Otte, D.M.3    Zimmer, A.4    Turck, C.W.5
  • 40
    • 84908884043 scopus 로고    scopus 로고
    • Chronic nicotine improves short-term memory selectively in a G72 mouse model of schizophrenia
    • 1:CAS:528:DC%2BC2cXktlCjs7g%3D 24417347 3966754
    • Hambsch B, Keyworth H, Lind J, Otte DM, Racz I, Kitchen I et al (2014) Chronic nicotine improves short-term memory selectively in a G72 mouse model of schizophrenia. Br J Pharmacol 171:1758-1771
    • (2014) Br J Pharmacol , vol.171 , pp. 1758-1771
    • Hambsch, B.1    Keyworth, H.2    Lind, J.3    Otte, D.M.4    Racz, I.5    Kitchen, I.6
  • 41
    • 80052708116 scopus 로고    scopus 로고
    • N-acetyl cysteine treatment rescues cognitive deficits induced by mitochondrial dysfunction in G72/G30 transgenic mice
    • 1:CAS:528:DC%2BC3MXhtFyms7fI 21716263 3176560
    • Otte DM, Sommersberg B, Kudin A, Guerrero C, Albayram O, Filiou MD et al (2011) N-acetyl cysteine treatment rescues cognitive deficits induced by mitochondrial dysfunction in G72/G30 transgenic mice. Neuropsychopharmacology 36:2233-2243
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2233-2243
    • Otte, D.M.1    Sommersberg, B.2    Kudin, A.3    Guerrero, C.4    Albayram, O.5    Filiou, M.D.6
  • 43
    • 33745689721 scopus 로고    scopus 로고
    • G72/G30 in schizophrenia and bipolar disorder: Review and meta-analysis
    • 1:CAS:528:DC%2BD28Xmsl2jtbY%3D 16581030
    • Detera-Wadleigh SD, McMahon FJ (2006) G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis. Biol Psychiatry 60:106-114
    • (2006) Biol Psychiatry , vol.60 , pp. 106-114
    • Detera-Wadleigh, S.D.1    McMahon, F.J.2
  • 44
    • 46249104490 scopus 로고    scopus 로고
    • Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database
    • 1:CAS:528:DC%2BD1cXnslKku7w%3D 18583979
    • Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ et al (2008) Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 40:827-834
    • (2008) Nat Genet , vol.40 , pp. 827-834
    • Allen, N.C.1    Bagade, S.2    McQueen, M.B.3    Ioannidis, J.P.4    Kavvoura, F.K.5    Khoury, M.J.6
  • 46
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study Consortium
    • Schizophrenia Psychiatric Genome-Wide Association Study Consortium (2011) Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43:969-976
    • (2011) Nat Genet , vol.43 , pp. 969-976
  • 47
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • 1:CAS:528:DC%2BC38XpvFGjtL0%3D 22777127 4110909
    • Sullivan PF, Daly MJ, O'Donovan M (2012) Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet 13:537-551
    • (2012) Nat Rev Genet , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 48
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia working group of the Psychiatric Genomics Consortium 4112379
    • Schizophrenia working group of the Psychiatric Genomics Consortium (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature 511:421-427
    • (2014) Nature , vol.511 , pp. 421-427
  • 49
    • 48749104001 scopus 로고    scopus 로고
    • Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia
    • 1:CAS:528:DC%2BD1cXps1GmtL4%3D 18423426
    • Hall J, Whalley HC, Moorhead TW, Baig BJ, McIntosh AM, Job DE et al (2008) Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia. Biol Psychiatry 64:428-433
    • (2008) Biol Psychiatry , vol.64 , pp. 428-433
    • Hall, J.1    Whalley, H.C.2    Moorhead, T.W.3    Baig, B.J.4    McIntosh, A.M.5    Job, D.E.6
  • 50
    • 78650013234 scopus 로고    scopus 로고
    • Genetic variation in G72 correlates with brain activation in the right middle temporal gyrus in a verbal fluency task in healthy individuals
    • 20336655
    • Krug A, Markov V, Krach S, Jansen A, Zerres K, Eggermann T et al (2011) Genetic variation in G72 correlates with brain activation in the right middle temporal gyrus in a verbal fluency task in healthy individuals. Hum Brain Mapp 32:118-126
    • (2011) Hum Brain Mapp , vol.32 , pp. 118-126
    • Krug, A.1    Markov, V.2    Krach, S.3    Jansen, A.4    Zerres, K.5    Eggermann, T.6
  • 51
    • 46849089287 scopus 로고    scopus 로고
    • Theory of mind and schizophrenia: A positron emission tomography study of medication-free patients
    • 18559406 2632446
    • Andreasen NC, Calarge CA, O'Leary DS (2008) Theory of mind and schizophrenia: a positron emission tomography study of medication-free patients. Schizophr Bull 34:708-719
    • (2008) Schizophr Bull , vol.34 , pp. 708-719
    • Andreasen, N.C.1    Calarge, C.A.2    O'Leary, D.S.3
  • 52
    • 78951469505 scopus 로고    scopus 로고
    • An fMRI study of "theory of mind" in at-risk states of psychosis: Comparison with manifest schizophrenia and healthy controls
    • 21147235
    • Brüne M, Ozgürdal S, Ansorge N, von Reventlow HG, Peters S, Nicolas V et al (2011) An fMRI study of "theory of mind" in at-risk states of psychosis: comparison with manifest schizophrenia and healthy controls. Neuroimage 55:329-337
    • (2011) Neuroimage , vol.55 , pp. 329-337
    • Brüne, M.1    Ozgürdal, S.2    Ansorge, N.3    Von Reventlow, H.G.4    Peters, S.5    Nicolas, V.6
  • 54
    • 34247863795 scopus 로고    scopus 로고
    • G72/G30 genes and schizophrenia: A systematic meta-analysis of association studies
    • 1:CAS:528:DC%2BD2sXkt1WgtL4%3D 17179078 1800627
    • Li D, He L (2007) G72/G30 genes and schizophrenia: a systematic meta-analysis of association studies. Genetics 175:917-922
    • (2007) Genetics , vol.175 , pp. 917-922
    • Li, D.1    He, L.2
  • 57
    • 84954376015 scopus 로고    scopus 로고
    • Genetic influences on the neural and physiological bases of acute threat: A research domain criteria (RDoC) perspective
    • Sumner JA, Powers A, Jovanovic T, Koenen K (2015) Genetic influences on the neural and physiological bases of acute threat: a research domain criteria (RDoC) perspective. Am J Med Genet Part B Neuropsychiatr.1718:44-64 doi: 10.1002/ajmg.b.32384
    • (2015) Am J Med Genet B Neuropsychiatr Part B , vol.1718 , pp. 44-64
    • Sumner, J.A.1    Powers, A.2    Jovanovic, T.3    Koenen, K.4
  • 58
    • 84901643079 scopus 로고    scopus 로고
    • Whole-genome analyses of whole-brain data: Working within an expanded search space
    • 1:CAS:528:DC%2BC2cXos1egtr4%3D 24866045 4300949
    • Medland SE, Jahanshad N, Neale BM, Thompson PM (2014) Whole-genome analyses of whole-brain data: working within an expanded search space. Nat Neurosci 17:791-800
    • (2014) Nat Neurosci , vol.17 , pp. 791-800
    • Medland, S.E.1    Jahanshad, N.2    Neale, B.M.3    Thompson, P.M.4
  • 59
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium 3912837
    • International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460:748-752
    • (2009) Nature , vol.460 , pp. 748-752
  • 61
    • 79953057217 scopus 로고    scopus 로고
    • Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia
    • 1:CAS:528:DC%2BC3MXitlerur4%3D 21346763 3351382
    • Vacic V, McCarthy S, Malhotra D, Murray F, Chou HH, Peoples A et al (2011) Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature 471:499-503
    • (2011) Nature , vol.471 , pp. 499-503
    • Vacic, V.1    McCarthy, S.2    Malhotra, D.3    Murray, F.4    Chou, H.H.5    Peoples, A.6
  • 62
    • 55749084543 scopus 로고    scopus 로고
    • Tilting at Quixotic Trait Loci (QTL): An evolutionary perspective on genetic causation
    • 18711218 2516055
    • Weiss KM (2008) Tilting at Quixotic Trait Loci (QTL): an evolutionary perspective on genetic causation. Genetics 179:1741-1756
    • (2008) Genetics , vol.179 , pp. 1741-1756
    • Weiss, K.M.1
  • 63
    • 84877723597 scopus 로고    scopus 로고
    • D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy
    • 1:CAS:528:DC%2BC3sXmt1ygtLY%3D 23116391
    • Sacchi S, Rosini E, Pollegioni L, Molla G (2013) d-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy. Curr Pharm Des 19:2499-2511
    • (2013) Curr Pharm des , vol.19 , pp. 2499-2511
    • Sacchi, S.1    Rosini, E.2    Pollegioni, L.3    Molla, G.4
  • 64
    • 84948407941 scopus 로고    scopus 로고
    • High-throughput screening strategy identifies allosteric, covalent human d-amino acid oxidase inhibitor
    • 1:CAS:528:DC%2BC28XlvVCktLw%3D 26296926
    • Terry-Lorenzo RT, Masuda K, Sugao K, Fang QK, Orsini MA, Sacchi S et al (2015) High-throughput screening strategy identifies allosteric, covalent human d-amino acid oxidase inhibitor. J Biomol Screen 20:1218-1231
    • (2015) J Biomol Screen , vol.20 , pp. 1218-1231
    • Terry-Lorenzo, R.T.1    Masuda, K.2    Sugao, K.3    Fang, Q.K.4    Orsini, M.A.5    Sacchi, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.