Clinical peculiarities of tuberculosis

BMC Infectious Diseases

Volumn 14, Issue , 2014, Pages

  Piccini, Paola ^a   Chiappini, Elena ^a   Tortoli, Enrico ^a   de Martino, Maurizio ^b   Galli, Luisa ^b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOSALICYLIC ACID; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIMYCOBACTERIAL AGENT; CAPREOMYCIN; CLARITHROMYCIN; CLOFAZIMINE; CYCLOSERINE; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; LEVOFLOXACIN; LINEZOLID; MEROPENEM; MOXIFLOXACIN; OFLOXACIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROTIONAMIDE; PYRAZINAMIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT;

AGE DISTRIBUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL TRANSMISSION; BACTERIUM DETECTION; CENTRAL NERVOUS SYSTEM TUBERCULOSIS; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; EYE TOXICITY; GASTRIC SUCTION; GENE MUTATION; HEADACHE; HEARING DISORDER; HUMAN; INCIDENCE; INTERFERON GAMMA RELEASE ASSAY; JAUNDICE; LATENT TUBERCULOSIS; LIVER TOXICITY; LUNG TUBERCULOSIS; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NAUSEA; OFF LABEL DRUG USE; PERIPHERAL NEUROPATHY; RASH; RELIABILITY; SPUTUM SMEAR; THORAX RADIOGRAPHY; TOXIC HEPATITIS; TUBERCULIN TEST; TUBERCULOSIS; TUBERCULOUS LYMPHADENITIS; TUBERCULOUS OSTEOMYELITIS;

EID: 84989344915     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-14-S1-S4     Document Type: Article

References (114)

1. Center for Disease Control and Prevention: Trends in Tuberculosis-United States, 2012. MMWR 2013, 62:201-205.
2. European Center for Disease Control and Prevention: Annual epidemiological report 2012. Reporting on 2010 surveillance data and 2011 epidemic intelligence data Stockholm: ECDC; 2013.
3. The World Health Organization: Global tuberculosis report 2012. Geneva: World Health Organization; 2012.
4. Marais BJ, Gie RP, Schaarf HS, Hesseling AC, Obihara CC, Nelson LJ, Earson DA, Donald PR, Beyers N: The clinical epidemiology of childhood pulmonary tuberculosis: a critical review of literature from the prechemotherapy era. Int J Tuberc Lung Dis 2004, 8:278-85.
5. Walls T, Shingadia D: Global epidemiology of pediatric tuberculosis. J Infect 2004, 48:13-22.
6. Nelson LJ, Wells CD: Global epidemiology of childhood tuberculosis. Int J Tuberc Lung Dis 2004, 8:636-47.
7. Marais BJ, Gie RP, Schaaf HS, Beyers N, Donald PR, Starke JR: Childhood pulmonary tuberculosis: old wisdom and new challenges. Am J Resp Crit Care Med 2006, 173:1078-1090.
8. Cruz AT, Starke JR: A current review of infection control for childhood tuberculosis. Tuberculosis (Edinb) 2011, 1S: S11-5.
9. Singh M, Mynak ML, Kumar L, Mathew JL, Jindal SK: Prevalence and risk factors for transmission of infection among children in household contact with adults having pulmonary tuberculosis. Arch Dis Child 2005, 90:624-8.
10. Roberts JR, Mason BW, Paranjhoty S, Parmer SR: The transmission of tuberculosis in schools involving children 3 to 11 years of age. Pediatr Infect Dis J 2011, 31:82-4.
11. Mtombmeni S, Mahomva A, Siziya C, Sanyika C, Doolabh R, Nathoo KJ: A clinical evaluation of children under the age of five years who are household contacts of adults with sputum positive tuberculosis in Harare, Zimbawe. Cent Afr J Med 2002, 48:28-32.
12. Totsmann A: Tuberculosis transmission by patients smear-negative pulmonary tuberculosis in a large cohort in The Netherlands. Clin Infect Dis 2009, 47:1135-1142.
13. Behr MA: Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli. Lancet 1999, 1135-1142.
14. Elwood RK, Cook VJ, Hernandez-Garduno E: Risk of tuberculosis in children from smear negative source cases. Int J Tuberc Lung Dis 2005, 9:49-55.
15. Phillips L, Carlile J, Smith D: Epidemiology of a tuberculosis outbreak in a rural Missouri high school. Pediatrics 2004, 113:e514-9.
16. Sacks JJ, Brenner ER, Breeden DC, Anders HM, Parker RL: Epidemiologyof a tuberculosis outbreak in a South Carolina junior high school. Am J Public Health 1985, 75:361-5.
17. Baghaie N, Khalilzadeh S, Bolursaz MR, Parsanejad N: Contact tracing of a 15-year-old girl with smear-negative pulmonary tuberculosis in Tehran. East Mediterr Health 2012, 18:399-401.
18. Caley M, Fowler T, Welch S, Wood A: Risk of developing tuberculosis from a school contact: retrospective cohort study, United Kingdom, 2009. Euro Surveill 2010, 15:1-4.
19. Paranjothy S, Eisenhut M, Lilley M, Bracebridge S, Abubakar I, Mulla R, Lack K, Chalkley D, Howard J, Thomas S, McEvoy M: Extensive transmission of mycobacterium tuberculosis from 9 years old child with pulmonary tuberculosis and negative sputum smear. BMJ 2008, 337:a1184, doi:10.1136/bmj.a1184.
20. Curtis AB, Ridzdon R, Vogel R, McDonough S, Hargreaves J, Ferry J, Valway S, Onorato IM: Extensive transmission of mycobacterium tuberculosis from a child. N Engl J Med 1999, 34:1491-5.
21. Cardona M, Bek MD, Mills K, Isaacs D, Alperstein G: Transmission of tuberculosis from a seven-year-old child in a Sydney school. J Pediatr Child Health 1999, 35:375-8.
22. Lee EH, Graham PL, O'Keefe M, Fuentes L, Saiman L: Nosocomial transmission of Mycobacterium tuberculosis in a children's hospital. Int J Tuberc Lung Dis 2005, 9:689-92.
23. Molicotti P, Bua A, Mela G, Olmeo P, Delogu R, Ortu S, Sechi LA, Zanetti S: Performance of quantiFERON-TB testing in a tuberculosis outbreak at a primary school. J Pediatr 2008, 152:585-6.
24. Reynolds DL, Gillis F, Kitai I, Deamond SL, Silverman M, King SM, Matlow AG, Crockett M: Transmission of Mycobacterium tuberculosis from an infant. Int J Tuberc Lung Dis 2006, 10:1051-6.
25. Ciofidegli Atti ML, Castelli Gattinara G, Ciliento G, Lancella L, Russo C, Coltella L, Vinci MR, Zaffina S, Raponi M: Prolonged in-hospital exposure to an infant with active pulmonary tuberculosis. Epidemiol Infect 2011, 139:139-42.
26. Griffith-Richards SB, Goussard P, Andronikou S, Andronikou S, Gie RP, Przybojewski SJ, Strachan M, Vadachia Y, Kathan DL: Cavitating pulmonary tuberculosis in children: correlating radiology with pathogenesis. Pediatr Radiol 2007, 37:798-804.
27. Carrol ED, Clark JE, Cant AJ: Non-pulmonary tuberculosis. Pediatr Respir Rev 2001, 2:113-9.
28. von Pirquet C: Frequency of tuberculosis in children. J Am Med Assoc 1909, 52:675-678.
29. American Academy of Pediatrics: Tuberculosis. In Red Book: 2012 Report of the Committee on Infectious Diseases. 28 edition. Elk Grove Village, IL: American Academy of Pediatrics;Pickering LK, Baker CJ, Kimberlin DW, Long SS 2012:.
30. Abubakar I, Griffiths C, Ormarod P: Guideline Development Group. Diagnosis of active and latent tuberculosis: summary of NICE guidance. BMJ 2012, 345:e6828.
31. Gideon HP, Flynn JL: Latent tuberculosis: what the host "sees"? Immunol Res 2011, 50:202-12.
32. Cruz AT, Starke JR: Pediatric tuberculosis. Pediatr Rev 2010, 31:13-25.
33. Mandalakas AM, Starke JS: Current concepts of childhood tuberculosis. Semin Pediatr Infect Dis 2005, 16:93-104.
34. Starke JR, Munoz FM: Tuberculosis. In Nelson Textbook of pediatrics. 18 edition. Saunders Elsevier;Kliegman RM, Jenson HB, Behrman RE, Stanton BF 2007:1240-1254.
35. Kim WS, Moon WK, Kim IO, Lee HJ, Im JG, Yeon KM, Han MC: Pulmonary tuberculosis in children: evaluation with CT. AJR Am J Roetgenol 1997, 168:1005-9.
36. Chakrabarti B, Davies PD: Pleural tuberculosis. Monaldi Arch Chest Dis 2006, 65:26-33.
37. Gie RP, Beyers N, Schaaf HS, Nel ED, Smuts NA, van Zyl S, Donald PR: TB or not TB?An evaluation of children an incorrect initial diagnosis of pulmonary tuberculosis. S Afr Med J 1995, 85:658-62.
38. Lzarus AA, Thilagar B: Tuberculosis of pericardium, larynx, and other uncommon sites. Dis Mon 2007, 53:46-54.
39. Marais BJ: Childhood tuberculosis: epidemiology and natural history of disease. Indian J Pediatr 2011, 78:321-327.
40. Erinie SA: An appraisal of the radiological features of pulmonary tuberculosis in Ilorin. Niger Postgrad Med J 2003, 10:264-9.
41. Lee EY, Tracy DA, Eisenberg RL, Arellano CM, Mahmood SA, Cleveland RH, Zurakowski D, Boiselle PM: Screening of asymptomatic children for tuberculosis is a lateral chest radiograph routinely indicated? Acad Radiol 2011, 18:184-90.
42. Delacourt C, Mani TM, Bonnerot V, de Blic J, Sayerg N, Lallemand D, Sheimann P: Computed tomography with normal chest radiograph in tuberculous infection. Arch Dis Child 1993, 69:430-432.
43. Donald PR: The chemotherapy of tuberculous lymphadenopathy in children. Tuberculosis 2010, 90:213-224.
44. Uysal G, Gursoy T, Guven A, Gunindi F, Cuhaci B: Clinical features of extrapulmonary tuberculosis in children. Saudi Med J 2005, 26:270-3.
45. Christensen AS, Andersen AB, Thomsen VO, Andersen PH, Johansen IS: Tuberculous meningitis in Denmark: a review of 50 cases. BMC Infect Dis 2011, 22:11-47.
46. Patayatchi N, Bamber S, Dawood H, Bobat R: Multidrug-resistant tuberculous meningitis in children in Durban, South Africa. Pediatr Infect Dis J 2006, 25:147-50.
47. Yaramis A, Gurkan F, Elevli M: Central nervous system tuberculosis in children: a review of 214 cases. Pediatrics 1998, 102:E49.
48. Farinha NJ, Razali KA, Holzel H, Morgan G, Novelli VM: Tuberculosis of the central nervous system in children: a 20-year survey. J Infect 2000, 41:61-68.
49. Anderson NE, Somaratne J, Holland D, Thomas MG: A review of tuberculous meningitis at Auckland city hospital, New Zeland. J of Clin Neurosc 2010, 1018-1022.
50. Singh DK, Rastogi M, Sharma A, Husain M: Unilateral hydrocephalus: atypical presentation of intracranial tuberculoma. Turk Neurosurg 2011, 21:242-5.
51. Tyagi DK, Balasubramanian S, Purandare HR, Savant HV: Intramedullary tuberculoma in a six years old. Neurol India 2010, 58:736-8.
52. Yanardag H, Uygun S, Yumuk V, Caner M, Canbaz B: Cerebral tuberculosis mimicking intracranial tumour. Singapore Med J 2005, 46:731-3.
53. Benzagmout M, Boujraf S, Chakour K, Chaoui Mel F: Pott's disease in children. SurgNeurol Int 2011, 11:2-1.
54. Mignone F, Calitri C, Scolfaro C, Garofalo S, Lonati L, Versace A, Tovo PA: An adolescent with persistent cervical lymphadenopathy and retropharyngeal abscess: case report. Minerva Pediatr 2013, 65:569-74.
55. Sultana A, Bhuiyan MS, Haque A, Bashar A, Islam MT, Rahman MM: Pattern of cutaneous tuberculosis among children and adolescent. Bangladesh Med Res Counc Bull 2012, 38:94-7.
56. Shah I, Rahangdale A: Ileal perforation in a child with abdominal tuberculosis. Ann Trop Paediatr 2010, 30:241-3.
57. Shah I, Uppuluri R: Clinical profile of abdominal tuberculosis in children. Indian J Med Sci 2010, 64:204-9.
58. Malaviya AN, Kotwal PP: Arthritis associated with tuberculosis. Best Pract Res Clin Rheumatol 2003, 17:319-43.
59. Eren A, Atay EF, Omeroglu H, Altintas F: Solitary cystic tuberculosis of long tubular bones in children. J Pediatr Orthop B 2003, 12:72-5.
60. Cantinotti M, De Gaudio M, de Martino M, Assanta N, Moschetti R, Veneruso G, Crocetti M, Murzi B, Chiappini E, Galli L: Intracardiac left atrial tuberculoma in an eleven-month-old infant: case report. MC Infect Dis 2011, 11:359.
61. Santos FC, Nascimento AL, Lira LA, Lima JF, Montenegro Rde A, Montenegro LM, Schindler HC: Bone tuberculosis: a case report on child. Rev Soc Bras Med Trop 2013, 46:249-51.
62. Bhatt GC, Nandan D, Singh S: Isolated tuberculous liver abscess in immunocompetent children-report of two cases. Pathog Glob Health 2013, 107:35-7.
63. Cox SG, Naidoo NG, Wood RJ, Clark L, Kilborn T: Tuberculous iliac artery aneurysm in a pediatric patient. J Vasc Surg 2013, 57:834-6.
64. Norazizah MA, Wan Hazabbah WH, Rohaizan Y, Shatriah I: Isolated optic neuritis secondary to presumed tuberculosis in an immunocompetent child. Med J Malaysia 2012, 67:102-4.
65. Singal R, Gupta S, Gupta S: Primary abdominal tuberculosis presenting as peritonitis in a young child-managed surgically. Asian Pac J Trop Med 2012, 5:413-5.
66. Prasad P, Bhardwaj M: Primary tuberculosis of tonsils: a case report. Case Rep Med 2012, 2012:120382.
67. Alp H, Orbak Z, Sepetcigil O, Kantarci M, Kartal I: Abdominal tuberculosis in a child presenting with radiological evidence of pneumatosis intestinalis and portal venous gas. J Health Popul Nutr 2010, 28:628-32.
68. Kumar V, Singh AP, Meher R, Raj A: Primary tuberculosis of oral cavity: a rare entity revisited. Indian J Pediatr 2011, 78:354-6.
69. Sookpotarom P, Nimanussornkul K, Luecha O, Poolsavatkitikool R, Vejchapipat P: Isolated tuberculosis of tunica vaginalis in a child. Pediatr Surg Int 2010, 26:763-5.
70. Tuli N: Orbital tuberculosis in childhood with intracranial extension: a case report. Cases J 2010, 28:3-38.
71. Mishra D, Singh S, Juneja M: Enterolithiasis: An uncommon finding in abdominal tuberculosis. Indian J Pediatr 2009, 76:1049-50.
72. Nerli RB, Kamat GV, Alur SB, Koura A, Vikram P, Amarkhed SS: Genitourinary tuberculosis in pediatric urological practice. J Pediatr Urol 2008, 4:299-303.
73. Shingadia D, Novelli V: Diagnosis and treatment of tuberculosis in children. Lancet Infect Dis 2003, 3:624-32.
74. Sun L, Xiao J, Miao Q, Feng WX, Wu XR, Yin QQ, Jiao WW, Shen C, Liu F, Shen D, Shen AD: Interferon gamma release assay in diagnosis of pediatric tuberculosis: a meta-analysis. FEMS Immunol Med Microbiol 2011, 63:165-173.
75. Chiappini E, Accetta G, Bonsignori F, Boddi V, Galli L, Biggeri A, de Martino M: Interferon-γrelease assays for the diagnosis of Mycobacterium tuberculosis infection in children: a systematic review and meta-analysis. Int J ImmunophatolPharmacol 2012, 25:557-64.
76. Lee JE, Kim HJ, Sei WL: The clinical utility of tuberculin skin test and interferon-γ release assay in the diagnosis of active tuberculosis among young adults: a prospective observational study. BMC infect Dis 2011, 18:11-96.
77. National Tuberculosis controllers Association, Centers for Disease Control and Prevention (CDC): Guidelines for the Investigation of Contacts Persons with Infectious Tuberculosis. Recommendations from the National Tuberculosis Controllers Association and CDC. MMWR Recomm Rep 2005, 54:1-47.
78. Fahrat M, Greenaway C, Pai M, Menzies D: False-positive tuberculin skin tests. What is the absolute effect of BCG and non-tuberculous mycobacteria? Int J Tuberc Dis 2006, 10:1192-1204.
79. Snider DE Jr: BacilleCalmette-Guerine vaccinations and tuberculin skin tests. JAMA 1985, 253:3438-39.
80. Siddiqi K, Lambert ML, Walley J: Clinical diagnosis of smear-negative pulmonary tuberculosus in low-income countries: the current evidence. Lancet Infect Dis 2003, 3:288-96.
81. Sarmiento OL, Weigle KA, Alexander J, Weber DJ, Ammerman AS: Assessment by meta-analysis of PCR for diagnosis of smear-negative pulmonary tuberculosis. J Clin Microbiol 2003, 41:3233-3240.
82. Center for Disease Control and Prevention: Update guidelines for the use of nucleic acid amplification tests in the diagnosis of tuberculosis. MMWR Morb Mortal Wkly Rep 2009, 58:7-10.
83. Bianchi L, Galli L, Moriondo M, Veneruso G, Becciolini L, Azzari C, Chiappini E, de Martino M: Interferon-gamma release assay improvediagnosis of tuberculosis in children. Pediatr Infect Dis J 2009, 28:510-514.
84. Starke J, Ong L, Eisenach K: Detection of M. tuberculosis in gastric aspirates samples from children using polymerase chain reaction. Am Rev Respir Dis 1993, 147:A801.
85. Smith K, Starke J, Eisenach K, Ong LT, Denby M: Detection of Mycobacterium tuberculosis in clinical specimens from children using a polymerase chain reaction. Paediatrics 1996, 97:155-60.
86. Tortoli E, Russo C, Piersimoni C, Mazzola E, Dal Monte P, Pascarella M, Borroni E, Mondo A, Piana F, Scarparo C, Coltella L, Lombardi G, Cirillo DM: Clinical validation of Xpert MTB/RIF for the diagnosis of extrapulmonary tuberculosis. Eur. Respir J 2012, 40:442-7.
87. Pai M, Kalantri S, Dheda K: New tools and emerging technologies for the diagnosis of tuberculosis: part II. Active tuberculosis and drug resistance. Expert Rev Mol Diagn 2006, 6:423-432.
88. Graham SM, Ahmed T, Amanullah F, Browning R, Cardenas V, Casenghi M, Cuevas LE, Gale M, Gie RP, Grzemska M, Handelsman E, Haterill M, Hesseling AC, Jean-Philippe P, Kampmann B, Kabra SK, Lienhardt C, Lighter-Fisher J, Madhi S, Makhene M, Marais BJ, McNeeley DF, Menzies H, Mitchell C, Modi S, Mofenson L, Musoke P, Nachman S, Powell C, Rigaud M, Rouzier V, Starke JR, Swaminathan S, Wingfield C: Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. J Infect Dis 2012, 15(Suppl 2):S199-208.
89. NICE Guidelines: CG33 Tuberculosis: Full Guideline.[http://www.nice.org. uk/guidance/].
90. American Thoracic Society: Targeted tuberculin testing and treatment of latent tuberculosis infection. MMWR Recomm Rep 2000, 49:1-51.
91. Public Health Agency of Canada, Canadian Lung Association: Canadian Tuberculosis Standards. Ottawa; 2007.
92. Centre for disease Control and Prevention: Treatment of Latent Tuberculosis Infection (LTBI). 2010 [www.cdc.gov/tb].
93. The World Health Organization: Treatment of tuberculosis. Guidelines, 4 2010 [http://who.int].
94. Ena J, Valls V: Short-course therapy with rifampin plus isoniazid, compared with standard therapy with isoniazid, for latent tuberculosis infection: a meta-analysis. Clin Infect Dis 2005, 40:670-6.
95. Graham SM: Treatment of paediatric TB: revised WHO guidelines. Pediatr Resp Rev 2011, 12:22-26.
96. Donald PR, Maher D, Maritz JS, Qazi S: Ethambutoldosage for the treatment of children: literature review and recommendations. Int J Tuberc Lung Dis 2006, 10:1318-30.
97. Jones DH, Russell-Eggitt I: Is It Necessary to Screen Children for Ethambutol Toxicity? Recommendations for Clinical Surveillance. Great Ormond Street Hospital for Children, London; 2010.
98. The World Health Organization:Rapid advice: Treatment of tuberculosis in children. Geneva; 2010 [http://who.int].
99. Mcllleron H, Willemse M, Werely CJ, Hussey GD, Schaaf HS, Smith PJ, Donald PR: Isoniazid plasma concentrations in a cohort of South African children with tuberculosis: implications for paediatric dosing guidelines. Clin Infect Dis 2009, 48:1547-53.
100. Veraghen LM, Lopez D, Hermans PW, Warris A, de Groot R, Garcia JF, de Waard JH, Aarnoutse RE: Pharmacokinetics of anti-tuberculosis drugs in Venezuelan children younger than 16 years of age: supportive evidence for the implementation of revised WHO dosing recommendations. Trop Med Int Health 2012, Epub ahead of print.
101. Donald PR: Antituberculosis drug-induced hepatotoxicity in children. Pediatr Rep 2011, 3:e16.
102. Thee S, Seddon JA, Donald PR, Seifart HI, Werely CJ, Hesseling AC, Rosenkranz B, Roll S, Schaaf HS: Pharmacokinetics of isoniazid, rifampicin, and pyrazinamide in children younger than two years of age with tuberculosis: evidence for implementation of revised World Health Organization recommendations. Antimicrob Agents Chemother 2011, 55:5560-7.
103. Tostmann A, Boeree MJ, Aarnoutse RE, de Lange WC, van der Ven AJ, Dekhuijzen R: Antituberculosis drug-induced hepatotoxicity: concise upto-date review. J Gastroent and Hepat 2008, 23:192-292.
104. Nolan CM, Goldberg SV, Buskin SE: Hepatotoxicity associated with isoniazid preventive therapy: a 7 years survey from a Public Health Tuberculosis Clinic. JAMA 1999, 281:1014-1018.
105. LoBue PA, Moser KS: Use of isoniazid for latent tuberculosis in a public health clinic. Am J Respir Crit Care Med 2003, 168:143-447.
106. Pande JN, Singh SP, Khilnani GC, Khilnani S, Tandon RK: Risk factors for hepatotoxicity from antituberculosis drugs: a case-control study. Thorax 1996, 51:132-136.
107. Ohkawa K, Hashiguchi M, Ohno K, Takahashi S, Kondo S, Echizen H, Ogata H: Risk factors for antituberculous chemotherapy-induced hepatotoxicity in Japanese pediatric patients. Clin Pharmacol Ther 2002, 72:220-226.
108. Pinon M, Scolfaro C, Bignamini E, Cordola G, Esposito I, Milano R, Mignone F, Bertaina C, Tovo PA: Two pediatric cases of multidrugresistant tuberculosis with linezolid and moxifloxacin. Pediatrics 2010, 126:e1253-6.
109. Seddon JA, Hesseling AC, Schaaf HS: Retooling existing tuberculosis drugs for children. Clin Infect Dis 2012, Epud ahead of print.
110. Burman WJ, Cotton MF, Gibb DM, Walker AS, Vernon AA, Donald PR: Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens. PLoS Med 2008, 5:e176.
111. Seddon JA, Hesseling AC, Marai BJ, Mcllleron H, Peloquin CA, Donald PR, Schaaf HS: Paediatric use of second-line anti-tuberculosis agents: a review. Tuberculosis (Edinb) 2012, 92:9-17.
112. Seddon JA, Thee S, Jacobs K, Ebrahim A, Hesseling AC, Schaaf AS: Hearing loss in children treated for multidrug-resistant tuberculosis. J Infect 2012, Epud ahead of print.
113. Thee S, Zollner EW, Willemse M, Hesseling AC, Magdorf K, Shaaf HS: Abnormal thyroid function tests in children on ethionamide treatment. Int J Tuberc Lung Dis 2011, 15:1191-1193.
114. Hoskins W: Paediatric tuberculosis. Postgrad Med J 2003, 79:272-278.