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Volumn 4, Issue 7, 2015, Pages

Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN DEPENDENT KINASE 9; CYCLIN T1; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; RNA; WNT PROTEIN;

EID: 84989336964     PISSN: None     EISSN: 21579024     Source Type: Journal    
DOI: 10.1038/oncsis.2015.20     Document Type: Article
Times cited : (34)

References (49)
  • 1
    • 34249810952 scopus 로고    scopus 로고
    • Adrenocortical cancer: Pathophysiology and clinical management
    • Libe R, Fratticci A, Bertherat J. Adrenocortical cancer: pathophysiology and clinical management. Endocr Relat Cancer 2007; 14: 13-28.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 13-28
    • Libe, R.1    Fratticci, A.2    Bertherat, J.3
  • 3
    • 8444251784 scopus 로고    scopus 로고
    • The wnt signaling pathway in development and disease
    • Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20: 781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 5
    • 84872498040 scopus 로고    scopus 로고
    • On the role of wnt/beta-catenin signaling in stem cells
    • Kuhl SJ, Kuhl M. On the role of Wnt/beta-catenin signaling in stem cells. Biochim Biophys Acta 2013; 1830: 2297-2306.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 2297-2306
    • Kuhl, S.J.1    Kuhl, M.2
  • 6
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell 2012; 149: 1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 7
    • 50649101532 scopus 로고    scopus 로고
    • Targeted disruption of beta-catenin in sf1-expressing cells impairs development and maintenance of the adrenal cortex
    • Kim AC, Reuter AL, Zubair M, Else T, Serecky K, Bingham NC et al. Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development 2008; 135: 2593-2602.
    • (2008) Development , vol.135 , pp. 2593-2602
    • Kim, A.C.1    Reuter, A.L.2    Zubair, M.3    Else, T.4    Serecky, K.5    Bingham, N.C.6
  • 10
    • 84865260495 scopus 로고    scopus 로고
    • Progression to adrenocortical tumorigenesis in mice and humans through insulinlike growth factor 2 and beta-catenin
    • Heaton JH, Wood MA, Kim AC, Lima LO, Barlaskar FM, Almeida MQ et al. Progression to adrenocortical tumorigenesis in mice and humans through insulinlike growth factor 2 and beta-catenin. Am J Pathol 2012; 181: 1017-1033.
    • (2012) Am J Pathol , vol.181 , pp. 1017-1033
    • Heaton, J.H.1    Wood, M.A.2    Kim, A.C.3    Lima, L.O.4    Barlaskar, F.M.5    Almeida, M.Q.6
  • 11
    • 49249137734 scopus 로고    scopus 로고
    • The t cell factor/beta-catenin antagonist pkf115-584 inhibits proliferation of adrenocortical carcinoma cells
    • Doghman M, Cazareth J, Lalli E. The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells. J Clin Endocrinol Metab 2008; 93: 3222-3225.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3222-3225
    • Doghman, M.1    Cazareth, J.2    Lalli, E.3
  • 12
    • 84873577222 scopus 로고    scopus 로고
    • Silencing mutated beta-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line h295r
    • Gaujoux S, Hantel C, Launay P, Bonnet S, Perlemoine K, Lefevre L et al. Silencing mutated beta-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R. PLoS ONE 2013; 8: e55743.
    • (2013) PLoS ONE , vol.8 , pp. e55743
    • Gaujoux, S.1    Hantel, C.2    Launay, P.3    Bonnet, S.4    Perlemoine, K.5    Lefevre, L.6
  • 13
    • 78449270065 scopus 로고    scopus 로고
    • Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers
    • Ragazzon B, Libe R, Gaujoux S, Assie G, Fratticci A, Launay P et al. Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers. Cancer Res 2010; 70: 8276-8281.
    • (2010) Cancer Res , vol.70 , pp. 8276-8281
    • Ragazzon, B.1    Libe, R.2    Gaujoux, S.3    Assie, G.4    Fratticci, A.5    Launay, P.6
  • 15
    • 79955409469 scopus 로고    scopus 로고
    • Functional characterization of the aff (af4/fmr2) family of RNA-binding proteins: Insights into the molecular pathology of fraxe intellectual disability
    • Melko M, Douguet D, Bensaid M, Zongaro S, Verheggen C, Gecz J et al. Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability. Hum Mol Genet 2011; 20: 1873-1885.
    • (2011) Hum Mol Genet , vol.20 , pp. 1873-1885
    • Melko, M.1    Douguet, D.2    Bensaid, M.3    Zongaro, S.4    Verheggen, C.5    Gecz, J.6
  • 16
    • 84864020768 scopus 로고    scopus 로고
    • The super elongation complex family of RNA polymerase II elongation factors: Gene target specificity and transcriptional output
    • Luo Z, Lin C, Guest E, Garrett AS, Mohaghegh N, Swanson S et al. The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Mol Cell Biol 2012; 32: 2608-2617.
    • (2012) Mol Cell Biol , vol.32 , pp. 2608-2617
    • Luo, Z.1    Lin, C.2    Guest, E.3    Garrett, A.S.4    Mohaghegh, N.5    Swanson, S.6
  • 17
    • 84877012261 scopus 로고    scopus 로고
    • Pharmacological modulation of beta-catenin and its applications in cancer therapy
    • Thakur R, Mishra DP. Pharmacological modulation of beta-catenin and its applications in cancer therapy. J Cell Mol Med 2013; 17: 449-456.
    • (2013) J Cell Mol Med , vol.17 , pp. 449-456
    • Thakur, R.1    Mishra, D.P.2
  • 18
    • 24744454197 scopus 로고    scopus 로고
    • Mutations of beta-catenin in adrenocortical tumors: Activation of the wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors
    • Tissier F, Cavard C, Groussin L, Perlemoine K, Fumey G, Hagnere AM et al. Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors. Cancer Res 2005; 65: 7622-7627.
    • (2005) Cancer Res , vol.65 , pp. 7622-7627
    • Tissier, F.1    Cavard, C.2    Groussin, L.3    Perlemoine, K.4    Fumey, G.5    Hagnere, A.M.6
  • 19
    • 53749096474 scopus 로고    scopus 로고
    • Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase a signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors
    • Gaujoux S, Tissier F, Groussin L, Libe R, Ragazzon B, Launay P et al. Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors. J Clin Endocrinol Metab 2008; 93: 4135-4140.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4135-4140
    • Gaujoux, S.1    Tissier, F.2    Groussin, L.3    Libe, R.4    Ragazzon, B.5    Launay, P.6
  • 20
    • 38049130282 scopus 로고    scopus 로고
    • Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas
    • Tadjine M, Lampron A, Ouadi L, Bourdeau I. Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas. Clin Endocrinol (Oxf) 2008; 68: 264-270.
    • (2008) Clin Endocrinol (Oxf , vol.68 , pp. 264-270
    • Tadjine, M.1    Lampron, A.2    Ouadi, L.3    Bourdeau, I.4
  • 21
    • 67349102249 scopus 로고    scopus 로고
    • Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: Implications for adrenocortical carcinoma
    • Kim A, Giordano TJ, Kuick R, Serecky K, Hammer GD. Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma. Ann Endocrinol (Paris) 2009; 70: 156.
    • (2009) Ann Endocrinol (Paris , vol.70 , pp. 156
    • Kim, A.1    Giordano, T.J.2    Kuick, R.3    Serecky, K.4    Hammer, G.D.5
  • 22
    • 79251475279 scopus 로고    scopus 로고
    • Beta-catenin activation is associated with specific clinical and pathologic characteristics and a poor outcome in adrenocortical carcinoma
    • Gaujoux S, Grabar S, Fassnacht M, Ragazzon B, Launay P, Libe R et al. beta-catenin activation is associated with specific clinical and pathologic characteristics and a poor outcome in adrenocortical carcinoma. Clin Cancer Res 2011; 17: 328-336.
    • (2011) Clin Cancer Res , vol.17 , pp. 328-336
    • Gaujoux, S.1    Grabar, S.2    Fassnacht, M.3    Ragazzon, B.4    Launay, P.5    Libe, R.6
  • 23
    • 79951719257 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway activation in adrenocortical adenomas is frequently due to somatic ctnnb1-Activating mutations, which are associated with larger and nonsecreting tumors: A study in cortisol-secreting and-nonsecreting tumors
    • Bonnet S, Gaujoux S, Launay P, Baudry C, Chokri I, Ragazzon B et al. Wnt/beta-catenin pathway activation in adrenocortical adenomas is frequently due to somatic CTNNB1-Activating mutations, which are associated with larger and nonsecreting tumors: a study in cortisol-secreting and-nonsecreting tumors. J Clin Endocrinol Metab 2011; 96: E419-E426.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. E419-E426
    • Bonnet, S.1    Gaujoux, S.2    Launay, P.3    Baudry, C.4    Chokri, I.5    Ragazzon, B.6
  • 25
    • 0037954576 scopus 로고    scopus 로고
    • Fusion of an af4-related gene, laf4, to mll in childhood acute lymphoblastic leukemia with t (2;11 q11;q23)
    • Hiwatari M, Taki T, Taketani T, Taniwaki M, Sugita K, Okuya M et al. Fusion of an AF4-related gene, LAF4, to MLL in childhood acute lymphoblastic leukemia with t (2;11)(q11;q23). Oncogene 2003; 22: 2851-2855.
    • (2003) Oncogene , vol.22 , pp. 2851-2855
    • Hiwatari, M.1    Taki, T.2    Taketani, T.3    Taniwaki, M.4    Sugita, K.5    Okuya, M.6
  • 26
    • 79954552505 scopus 로고    scopus 로고
    • The super elongation complex (sec) and mll in development and disease
    • Smith E, Lin C, Shilatifard A. The super elongation complex (SEC) and MLL in development and disease. Genes Dev 2011; 25: 661-672.
    • (2011) Genes Dev , vol.25 , pp. 661-672
    • Smith, E.1    Lin, C.2    Shilatifard, A.3
  • 27
    • 0036292550 scopus 로고    scopus 로고
    • The mouse laf4 gene: Exon/intron organization, cdna sequence, alternative splicing, and expression during central nervous system development
    • Britanova O, Lukyanov S, Gruss P, Tarabykin V. The mouse Laf4 gene: exon/intron organization, cDNA sequence, alternative splicing, and expression during central nervous system development. Genomics 2002; 80: 31-37.
    • (2002) Genomics , vol.80 , pp. 31-37
    • Britanova, O.1    Lukyanov, S.2    Gruss, P.3    Tarabykin, V.4
  • 29
    • 84940325910 scopus 로고    scopus 로고
    • Laf4/aff3, a gene involved in intellectual disability, is required for cellular migration in the mouse cerebral cortex
    • Moore JM, Oliver PL, Finelli MJ, Lee S, Lickiss T, Molnar Z et al. Laf4/Aff3, a gene involved in intellectual disability, is required for cellular migration in the mouse cerebral cortex. PLoS One 2014; 9: e105933.
    • (2014) PLoS One , vol.9 , pp. e105933
    • Moore, J.M.1    Oliver, P.L.2    Finelli, M.J.3    Lee, S.4    Lickiss, T.5    Molnar, Z.6
  • 30
    • 67449091146 scopus 로고    scopus 로고
    • Identification of af4/fmr2 family, member 3 (aff3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-Autoimmune susceptibility genes
    • Barton A, Eyre S, Ke X, Hinks A, Bowes J, Flynn E et al. Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-Autoimmune susceptibility genes. Hum Mol Genet 2009; 18: 2518-2522.
    • (2009) Hum Mol Genet , vol.18 , pp. 2518-2522
    • Barton, A.1    Eyre, S.2    Ke, X.3    Hinks, A.4    Bowes, J.5    Flynn, E.6
  • 31
    • 77955434703 scopus 로고    scopus 로고
    • Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a european cohort increases the evidence for nine markers
    • Plant D, Flynn E, Mbarek H, Dieude P, Cornelis F, Arlestig L et al. Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers. Ann Rheum Dis 2010; 69: 1548-1553.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1548-1553
    • Plant, D.1    Flynn, E.2    Mbarek, H.3    Dieude, P.4    Cornelis, F.5    Arlestig, L.6
  • 32
    • 77952888454 scopus 로고    scopus 로고
    • Genomewide association study meta-Analysis identifies seven new rheumatoid arthritis risk loci
    • Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP et al. Genomewide association study meta-Analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010; 42: 508-514.
    • (2010) Nat Genet , vol.42 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3    Xie, G.4    Eyre, S.5    Thomson, B.P.6
  • 33
    • 79953705986 scopus 로고    scopus 로고
    • Genome-wide association study of rheumatoid arthritis in koreans: Population-specific loci as well as overlap with european susceptibility loci
    • Freudenberg J, Lee HS, Han BG, Shin HD, Kang YM, Sung YK et al. Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci. Arthritis Rheum 2011; 63: 884-893.
    • (2011) Arthritis Rheum , vol.63 , pp. 884-893
    • Freudenberg, J.1    Lee, H.S.2    Han, B.G.3    Shin, H.D.4    Kang, Y.M.5    Sung, Y.K.6
  • 34
    • 84861719484 scopus 로고    scopus 로고
    • Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
    • Wallace C, Rotival M, Cooper JD, Rice CM, Yang JH, McNeill M et al. Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes. Hum Mol Genet 2012; 21: 2815-2824.
    • (2012) Hum Mol Genet , vol.21 , pp. 2815-2824
    • Wallace, C.1    Rotival, M.2    Cooper, J.D.3    Rice, C.M.4    Yang, J.H.5    McNeill, M.6
  • 38
    • 0034636153 scopus 로고    scopus 로고
    • Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin d1 expression and cancer progression
    • Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y et al. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA 2000; 97: 4262-4266.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4262-4266
    • Lin, S.Y.1    Xia, W.2    Wang, J.C.3    Kwong, K.Y.4    Spohn, B.5    Wen, Y.6
  • 40
    • 84893370802 scopus 로고    scopus 로고
    • An rnai screen for aire cofactors reveals a role for hnrnpl in polymerase release and aire-Activated ectopic transcription
    • Giraud M, Jmari N, Du L, Carallis F, Nieland TJ, Perez-Campo FM et al. An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-Activated ectopic transcription. Proc Natl Acad Sci USA 2014; 111: 1491-1496.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 1491-1496
    • Giraud, M.1    Jmari, N.2    Du, L.3    Carallis, F.4    Nieland, T.J.5    Perez-Campo, F.M.6
  • 41
    • 80054984945 scopus 로고    scopus 로고
    • Inhibition of bet recruitment to chromatin as an effective treatment for mll-fusion leukaemia
    • Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 2011; 478: 529-533.
    • (2011) Nature , vol.478 , pp. 529-533
    • Dawson, M.A.1    Prinjha, R.K.2    Dittmann, A.3    Giotopoulos, G.4    Bantscheff, M.5    Chan, W.I.6
  • 42
    • 80052955256 scopus 로고    scopus 로고
    • Bet bromodomain inhibition as a therapeutic strategy to target c-myc
    • Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM et al. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 2011; 146: 904-917.
    • (2011) Cell , vol.146 , pp. 904-917
    • Delmore, J.E.1    Issa, G.C.2    Lemieux, M.E.3    Rahl, P.B.4    Shi, J.5    Jacobs, H.M.6
  • 43
    • 80055000824 scopus 로고    scopus 로고
    • Rnai screen identifies brd4 as a therapeutic target in acute myeloid leukaemia
    • Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 2011; 478: 524-528.
    • (2011) Nature , vol.478 , pp. 524-528
    • Zuber, J.1    Shi, J.2    Wang, E.3    Rappaport, A.R.4    Herrmann, H.5    Sison, E.A.6
  • 44
    • 0034457810 scopus 로고    scopus 로고
    • Loss of expression of the ubiquitous transcription factor camp response element-binding protein (creb) and compensatory overexpression of the activator cremtau in the human adrenocortical cancer cell line h295r
    • Groussin L, Massias JF, Bertagna X, Bertherat J. Loss of expression of the ubiquitous transcription factor cAMP response element-binding protein (CREB) and compensatory overexpression of the activator CREMtau in the human adrenocortical cancer cell line H295R. J Clin Endocrinol Metab 2000; 85: 345-354.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 345-354
    • Groussin, L.1    Massias, J.F.2    Bertagna, X.3    Bertherat, J.4
  • 45
    • 70349742485 scopus 로고    scopus 로고
    • Inactivation of the carney complex gene 1 (protein kinase a regulatory subunit 1 a) inhibits smad3 expression and tgf beta-stimulated apoptosis in adrenocortical cells
    • Ragazzon B, Cazabat L, Rizk-Rabin M, Assie G, Groussin L, Fierrard H et al. Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1 A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells. Cancer Res 2009; 69: 7278-7284.
    • (2009) Cancer Res , vol.69 , pp. 7278-7284
    • Ragazzon, B.1    Cazabat, L.2    Rizk-Rabin, M.3    Assie, G.4    Groussin, L.5    Fierrard, H.6
  • 46
    • 84888310600 scopus 로고    scopus 로고
    • Armc5 mutations in macronodular adrenal hyperplasia with cushing's syndrome
    • Assie G, Libe R, Espiard S, Rizk-Rabin M, Guimier A, Luscap W et al. ARMC5 mutations in macronodular adrenal hyperplasia with Cushing's syndrome. N Engl J Med 2013; 369: 2105-2114.
    • (2013) N Engl J Med , vol.369 , pp. 2105-2114
    • Assie, G.1    Libe, R.2    Espiard, S.3    Rizk-Rabin, M.4    Guimier, A.5    Luscap, W.6
  • 47
    • 36849073202 scopus 로고    scopus 로고
    • Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer
    • Doghman M, Karpova T, Rodrigues GA, Arhatte M, De Moura J, Cavalli LR et al. Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer. Mol Endocrinol 2007; 21: 2968-2987.
    • (2007) Mol Endocrinol , vol.21 , pp. 2968-2987
    • Doghman, M.1    Karpova, T.2    Rodrigues, G.A.3    Arhatte, M.4    De Moura, J.5    Cavalli, L.R.6
  • 48
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6
  • 49
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • Bolte S, Cordelieres FP. A guided tour into subcellular colocalization analysis in light microscopy. J Microsc 2006; 224: 213-232.
    • (2006) J Microsc , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelieres, F.P.2


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