FRA2A Is a CGG Repeat Expansion Associated with Silencing of AFF3

PLoS Genetics

Volumn 10, Issue 4, 2014, Pages

  Metsu, Sofie ^a   Rooms, Liesbeth ^a   Rainger, Jacqueline ^b   Taylor, Martin S ^b   Bengani, Hemant ^b   Wilson, David I ^c   Chilamakuri, Chandra Sekhar Reddy ^d   Morrison, Harris ^b   Vandeweyer, Geert ^a   Reyniers, Edwin ^a   Douglas, Evelyn ^e   Thompson, Geoffrey ^f,g   Haan, Eric ^e,h   Gecz, Jozef ^e,f   FitzPatrick, David R ^b   Kooy, R Frank ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

^e Genetics and Molecular Pathology   (Australia)

^f UNIVERSITY OF ADELAIDE   (Australia)

^g FLINDERS UNIVERSITY   (Australia)

^h WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; AFF3 PROTEIN, HUMAN; FOSL2 PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR FRA 2;

AFF2 GENE; AFF3 GENE; ANIMAL TISSUE; ARTICLE; CHROMOSOME ANALYSIS; CYTOGENETICS; DNA METHYLATION; EMBRYO; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FMR2 GENE; FRA2A GENE; GENE; GENE EXPRESSION; GENE SILENCING; HAPLOINSUFFICIENCY; HUMAN; LANGUAGE DELAY; MALE; MOSAICISM; MOTOR PERFORMANCE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROMOTER REGION; PYROSEQUENCING; SINGLE NUCLEOTIDE POLYMORPHISM; TRINUCLEOTIDE REPEAT; ALLELE; CHROMOSOME FRAGILE SITE; GENETICS; INTELLECTUAL IMPAIRMENT;

ALLELES; CHROMOSOME FRAGILE SITES; DNA METHYLATION; FEMALE; FOS-RELATED ANTIGEN-2; GENE EXPRESSION; HUMANS; INTELLECTUAL DISABILITY; MALE; NUCLEAR PROTEINS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84901302565     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004242     Document Type: Article

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