Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function (Nature Communications (2016) 7 (12862) DOI: 10.1038/ncomms12862);14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

Nature Communications

Volumn 7, Issue , 2016, Pages

  Schoenwaelder, Simone M ^a,b,c   Darbousset, Roxane ^a,b,c   Cranmer, Susan L ^c   Ramshaw, Hayley S ^d   Orive, Stephanie L ^c   Sturgeon, Sharelle ^c   Yuan, Yuping ^a,b,c   Yao, Yu ^c   Krycer, James R ^b   Woodcock, Joanna ^d   Maclean, Jessica ^a,b,c   Pitson, Stuart ^d   Zheng, Zhaohua ^c   Henstridge, Darren C ^e   Van Der Wal, Dianne ^c   Gardiner, Elizabeth E ^c,f   Berndt, Michael C ^g   Andrews, Robert K ^c   James, David E ^b,h   Lopez, Angel F ^d   Jackson, Shaun P ^a,b,c,i   more..

^a HEART RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^e BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^f Australian National University   (Australia)

^g CURTIN UNIVERSITY   (Australia)

^h UNIVERSITY OF SYDNEY   (Australia)

ⁱ SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; PHOSPHATIDYLSERINE; PROCOAGULANT; PROTEIN 14 3 3; PROTEIN 14 3 3 ZETA; THROMBIN RECEPTOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

APOPTOSIS; BIOENERGETICS; CELLS AND CELL COMPONENTS; COAGULATION; GENE; LIPID; METABOLISM; MITOCHONDRION; RESPIRATION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; BLEEDING TIME; BLOOD CLOTTING; CALCIUM TRANSPORT; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; DEPOLARIZATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LUNG EMBOLISM; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTEIN FUNCTION; REGULATORY MECHANISM; SURVIVAL; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOEMBOLISM;

MUS;

EID: 84989331449     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms16125     Document Type: Erratum

References (70)

1. Mackintosh, C. Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes. Biochem. J. 381, 329-342 (2004).
2. Pozuelo Rubio, M. et al. 14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking. Biochem. J. 379, 395-408 (2004).
3. Morrison, D. K. The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol. 19, 16-23 (2009).
4. Kleppe, R., Martinez, A., Doskeland, S. O. & Haavik, J. The 14-3-3 proteins in regulation of cellular metabolism. Semin. Cell Dev. Biol. 22, 713-719 (2011).
5. Jackson, S. P. Arterial thrombosis-insidious, unpredictable and deadly. Nat. Med. 17, 1423-1436 (2011).
6. Jackson, S. P., Nesbitt, W. S. & Westein, E. Dynamics of platelet thrombus formation. J. Thromb. Haemost. 7(Suppl 1): 17-20 (2009).
7. Ruggeri, Z. M. Platelets in atherothrombosis. Nat. Med. 8, 1227-1234 (2002).
8. Du, X., Harris, S. J., Tetaz, T. J., Ginsberg, M. H. & Berndt, M. C. Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex. J. Biol. Chem. 269, 18287-18290 (1994).
9. Gu, M., Xi, X., Englund, G. D., Berndt, M. C. & Du, X. Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model. J. Cell Biol. 147, 1085-1096 (1999).
10. Mangin, P. et al. Identification of a novel 14-3-3{zeta} binding site within the cytoplasmic tail of platelet glycoprotein Ib{alpha}. Blood 104, 420-427 (2004).
11. Bialkowska, K., Zaffran, Y., Meyer, S. C. & Fox, J. E. 14-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta. J. Biol. Chem. 278, 33342-33350 (2003).
12. Zaffran, Y., Meyer, S. C., Negrescu, E., Reddy, K. B. & Fox, J. E. Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces alpha IIbbeta 3 activation both in platelets and a transfected Chinese hamster ovary cell system. J. Biol. Chem. 275, 16779-16787 (2000).
13. Dai, K., Bodnar, R., Berndt, M. C. & Du, X. A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood 106, 1975-1981 (2005).
14. Cunningham, J. G., Meyer, S. C. & Fox, J. E. The cytoplasmic domain of the alpha-subunit of glycoprotein (GP) Ib mediates attachment of the entire GP Ib-IX complex to the cytoskeleton and regulates von Willebrand factor-induced changes in cell morphology. J. Biol. Chem. 271, 11581-11587 (1996).
15. Kanaji, T. et al. Megakaryocyte proliferation and ploidy regulated by the cytoplasmic tail of glycoprotein Ibalpha. Blood 104, 3161-3168 (2004).
16. Mu, F. T. et al. A functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex. Blood 111, 4580-4587 (2008).
17. Mu, F. T., Cranmer, S. L., Andrews, R. K. & Berndt, M. C. Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibalpha, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex. J. Thromb. Haemost. 8, 324-330 (2010).
18. Mangin, P. H. et al. Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets. J. Thromb. Haemost. 7, 1550-1555 (2009).
19. Cheah, P. S. et al. Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3zeta deficiency. Mol. Psychiatry 17, 451-466 (2011).
20. Mangin, P. et al. Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency. Blood 107, 4346-4353 (2006).
21. Morowski, M. et al. Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice. Blood 121, 4938-4947 (2013).
22. Schoenwaelder, S. M. et al. Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets. Blood 118, 1663-1674 (2011).
23. Woodcock, J. M. et al. Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics. Oncotarget 6, 14522-14536 (2015).
24. Michelson, A. D. Antiplatelet therapies for the treatment of cardiovascular disease. Nat. Rev. Drug Discov. 9, 154-169 (2010).
25. Kulkarni, S., Woollard, K. J., Thomas, S., Oxley, D. & Jackson, S. P. Conversion of platelets from a proaggregatory to a proinflammatory adhesive phenotype: role of PAF in spatially regulating neutrophil adhesion and spreading. Blood 110, 1879-1886 (2007).
26. Schoenwaelder, S. M. et al. Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function. Blood 114, 663-666 (2009).
27. Choi, J. H., Kim, S. & Kim, S. J. Spirulan from blue-green algae inhibits fibrin and blood clots: its potent antithrombotic effects. J. Biochem. Mol. Toxicol. 29, 240-248 (2015).
28. Mizurini, D. M., Francischetti, I. M. & Monteiro, R. Q. Aegyptin inhibits collagen-induced coagulation activation in vitro and thromboembolism in vivo. Biochem. Biophys. Res. Commun. 436, 235-239 (2013).
29. Kidd, J. F. et al. Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore. J. Biol. Chem. 277, 6504-6510 (2002).
30. Jackson, S. P. & Schoenwaelder, S. M. Procoagulant platelets: are they necrotic? Blood 116, 2011-2018 (2010).
31. Lhermusier, T., Chap, H. & Payrastre, B. Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome. J. Thromb. Haemost. 9, 1883-1891 (2011).
32. Corton, J. M., Gillespie, J. G. & Hardie, D. G. Role of the AMP-activated protein kinase in the cellular stress response. Curr. Biol. 4, 315-324 (1994).
33. Kramer, P. A., Ravi, S., Chacko, B., Johnson, M. S. & Darley-Usmar, V. M. A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: implications for their use as bioenergetic biomarkers. Redox Biol. 2, 206-210 (2014).
34. Paglia, G. et al. Comprehensive metabolomic study of platelets reveals the expression of discrete metabolic phenotypes during storage. Transfusion 54, 2911-2923 (2014).
35. Aducci, P., Camoni, L., Marra, M. & Visconti, S. From cytosol to organelles: 14-3-3 proteins as multifunctional regulators of plant cell. IUBMB Life 53, 49-55 (2002).
36. de Boer, A. H. Plant 14-3-3 proteins assist ion channels and pumps. Biochem. Soc. Trans. 30, 416-421 (2002).
37. Andrews, R. K., Harris, S. J., McNally, T. & Berndt, M. C. Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. Biochemistry 37, 638-647 (1998).
38. Calverley, D. C., Kavanagh, T. J. & Roth, G. J. Human signaling protein 14-3-3zeta interacts with platelet glycoprotein Ib subunits Ibalpha and Ibbeta. Blood 91, 1295-1303 (1998).
39. Feng, S., Christodoulides, N., Resendiz, J. C., Berndt, M. C. & Kroll, M. H. Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V. Blood 95, 551-557 (2000).
40. Munday, A. D., Berndt, M. C. & Mitchell, C. A. Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. Blood 96, 577-584 (2000).
41. Yuan, Y. et al. Identification of a novel 14-3-3zeta binding site within the cytoplasmic domain of platelet glycoprotein Ibalpha that plays a key role in regulating the von Willebrand factor binding function of glycoprotein Ib-IX. Circ. Res. 105, 1177-1185 (2009).
42. Zhang, W. et al. Role of 14-3-3zeta in platelet glycoprotein Ibalpha-von Willebrand factor interaction-induced signaling. Int. J. Mol. Sci. 13, 5364-5374 (2012).
43. Mason, K. D. et al. Programmed anuclear cell death delimits platelet life span. Cell 128, 1173-1186 (2007).
44. Chacko, B. K. et al. The Bioenergetic Health Index: a new concept in mitochondrial translational research. Clin. Sci. 127, 367-373 (2014).
45. Bonora, M., Bravo-San Pedro, J. M., Kroemer, G., Galluzzi, L. & Pinton, P. Novel insights into the mitochondrial permeability transition. Cell Cycle 13, 2666-2670 (2014).
46. Bonora, M. et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene 34, 1475-1486 (2015).
47. Giorgioa, V. et al. Dimers of mitochondrial ATP synthase form the permeability transition pore. Proc. Natl Acad. Sci. USA 110, 5887-5892 (2013).
48. Morciano, G. et al. Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury. J. Mol. Cell Cardiol. 78, 142-153 (2015).
49. Bunney, T. D., van den Wijngaard, P. W. & de Boer, A. H. 14-3-3 protein regulation of proton pumps and ion channels. Plant Mol. Biol. 50, 1041-1051 (2002).
50. Bunney, T. D., van Walraven, H. S. & de Boer, A. H. 14-3-3 protein is a regulator of the mitochondrial and chloroplast ATP synthase. Proc. Natl Acad. Sci. USA 98, 4249-4254 (2001).
51. Braun, A. et al. Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation. Blood 113, 2056-2063 (2009).
52. Varga-Szabo, D., Braun, A. & Nieswandt, B. STIM and Orai in platelet function. Cell Calcium 50, 270-278 (2011).
53. Yang, X. et al. Targeting 14-3-3zeta in cancer therapy. Cancer Gene Ther. 19, 153-159 (2012).
54. Zhao, J., Meyerkord, C. L., Du, Y., Khuri, F. R. & Fu, H. 14-3-3 proteins as potential therapeutic targets. Semin. Cell Dev. Biol. 22, 705-712 (2011).
55. Matta, A. et al. Prognostic significance of head-and-neck cancer biomarkers previously discovered and identified using iTRAQ-labeling and multidimensional liquid chromatography-tandem mass spectrometry. J. Proteome Res. 7, 2078-2087 (2008).
56. Chatterjee, D. et al. Reduction of 9-nitrocamptothecin-triggered apoptosis in DU-145 human prostate cancer cells by ectopic expression of 14-3-3zeta. Int. J. Oncol. 25, 503-509 (2004).
57. Choi, J. E. et al. Silencing of 14-3-3zeta over-expression in hepatocellular carcinoma inhibits tumor growth and enhances chemosensitivity to cis-diammined dichloridoplatium. Cancer Lett. 303, 99-107 (2011).
58. Ge, F. et al. Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells. J. Proteome Res. 8, 3006-3019 (2009).
59. Dammacco, F. et al. Cancer-related coagulopathy (Trousseaus syndrome): review of the literature and experience of a single center of internal medicine. Clin. Exp. Med. 13, 85-97 (2013).
60. Hisada, Y., Geddings, J. E., Ay, C. & Mackman, N. Venous thrombosis and cancer: from mouse models to clinical trials. J. Thromb. Haemost. 13, 1372-1382 (2015).
61. Sousou, T. & Khorana, A. A. New insights into cancer-associated thrombosis. Arterioscler. Thromb. Vasc. Biol. 29, 316-320 (2009).
62. Monreal, M. et al. Fatal pulmonary embolism and fatal bleeding in cancer patients with venous thromboembolism: findings from the RIETE registry. J. Thromb. Haemost. 4, 1950-1956 (2006).
63. Cranmer, S. L. et al. High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIb{alpha}-filamin interaction. Blood 117, 2718-2727 (2011).
64. Donnelly, D. S., Zelterman, D., Sharkis, S. & Krause, D. S. Functional activity of murine CD34 and CD34- hematopoietic stem cell populations. Exp. Hematol. 27, 788-796 (1999).
65. Maxwell, M. J. et al. SHIP1 and Lyn kinase negatively regulate integrin alpha IIb beta 3 signaling in platelets. J. Biol. Chem. 279, 32196-32204 (2004).
66. Daniel, J. L., Molish, I. R. & Holmsen, H. Radioactive labeling of the adenine nucleotide pool of cells as a method to distinguish among intracellular compartments. Studies on human platelets. Biochim. Biophys. Acta 632, 444-453 (1980).
67. Holmsen, H., Storm, E. & Day, H. J. Determination of ATP and ADP in blood platelets: a modification of the firefly luciferase assay for plasma. Anal. Biochem. 46, 489-501 (1972).
68. Carrette, O., Burkhard, P. R., Sanchez, J. C. & Hochstrasser, D. F. State-of-the-art two-dimensional gel electrophoresis: a key tool of proteomics research. Nat. Protoc. 1, 812-823 (2006).
69. Mangin, P. et al. A PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1. FEBS Lett. 542, 53-59 (2003).
70. Schoenwaelder, S. M. et al. Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets. J. Biol. Chem. 282, 28648-28658 (2007).