Identification of a novel 14-3-3ζ binding site within the cytoplasmic domain of platelet glycoprotein Ibα that plays a key role in regulating the von willebrand factor binding function of glycoprotein Ib-IX

Circulation Research

Volumn 105, Issue 12, 2009, Pages 1177-1185

  Yuan, Yanhong ^a   Zhang, Weilin ^a   Yan, Rong ^a   Liao, Yi ^a   Zhao, Lili ^a   Ruan, Changgeng ^b   Du, Xiaoping ^c   Dai, Kesheng ^a  

^a BEIHANG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c UNIVERSITY OF ILLINOIS   (United States)

Author keywords

14 3 3 ; GPIb ; Platelets; Thrombosis; Von Willebrand factor

Indexed keywords

FILAMIN A; GLYCOPROTEIN IB; GLYCOPROTEIN IB ALPHA; GLYCOPROTEIN IB IX; STRATIFIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; ACTIN BINDING PROTEIN; CONTRACTILE PROTEIN; FILAMINS; PEPTIDE; PROTEIN 14 3 3; RECOMBINANT PROTEIN; RISTOCETIN; THROMBIN RECEPTOR;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHO CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; THROMBOCYTE ADHESION; THROMBOGENESIS; THROMBOSIS; ANIMAL; CELL MEMBRANE PERMEABILITY; CRICETULUS; CYTOPLASM; CYTOSKELETON; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; THROMBOCYTE; THROMBOCYTE ADHESIVENESS;

14-3-3 PROTEINS; ANIMALS; BINDING SITES; BLOOD PLATELETS; CELL MEMBRANE PERMEABILITY; CHO CELLS; CONTRACTILE PROTEINS; CRICETINAE; CRICETULUS; CYTOPLASM; CYTOSKELETON; HUMANS; MICROFILAMENT PROTEINS; MUTATION; PEPTIDES; PHOSPHORYLATION; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RISTOCETIN; TRANSFECTION; VON WILLEBRAND FACTOR;

EID: 73349085606     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.204669     Document Type: Article

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