Role of 14-3-3ζ in platelet glycoprotein Ibα-von willebrand factor interaction-induced signaling

International Journal of Molecular Sciences

Volumn 13, Issue 5, 2012, Pages 5364-5374

  Zhang, Weilin ^a   Zhao, Lili ^a   Liu, Jun ^a   Du, Juan ^a   Yan, Rong ^b   Dai, Kesheng ^b  

^a BEIHANG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

14 3 3 ; Glycoprotein (GP) Ib IX; Platelets; Von willebrand factor (VWF)

Indexed keywords

ALANINE; CALCIUM ION; GLYCOPROTEIN IB ALPHA; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; SERINE; STRATIFIN; VON WILLEBRAND FACTOR; PROTEIN 14 3 3; THROMBIN RECEPTOR;

ARTICLE; BINDING AFFINITY; CALCIUM SIGNALING; CYTOMETRY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; INHIBITION KINETICS; INTRACELLULAR SIGNALING; MUTATIONAL ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; CHO CELL LINE; CRICETULUS; GENETICS; HUMAN; METABOLISM; POINT MUTATION; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; ANIMALS; CHO CELLS; CRICETULUS; HUMANS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; POINT MUTATION; PROTEIN INTERACTION MAPS; SIGNAL TRANSDUCTION; VON WILLEBRAND FACTOR;

EID: 84861563971     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13055364     Document Type: Article

References (25)

1. Lopez, J.A. The platelet glycoprotein Ib-IX complex. Blood Coagul. Fibrinolysis 1994, 5, 97-119.
2. Du, X. Signaling and regulation of the glycoprotein Ib-IX-V complex. Curr. Opin. Hematol. 2007, 14, 262-269.
3. Andrews, R.K.; Berndt, M.C. Platelet adhesion: A game of catch and release. J. Clin. Invest. 2008, 118, 3009-3011.
4. Kroll, M.H.; Harris, T.S.; Moake, J.L.; Handin, R.I.; Schafer, A.I. Von Willebrand factor binding to platelet GPIb initiates signals for platelet activation. J. Clin. Invest. 1991, 88, 1568-1573.
5. Kasirer-Friede, A.; Cozzi, M.R.; Mazzucato, M.; De Marco, L.; Ruggeri, Z.M.; Shattil, S.J. Signaling through GP Ib-IX-V activates αIIbβ3 independently of other receptors. Blood 2004, 103, 3403-3411.
6. Feng, S.; Resendiz, J.C.; Lu, X.; Kroll, M.H. Filamin A binding to the cytoplasmic tail of glycoprotein Ibα regulates von Willebrand factor-induced platelet activation. Blood 2003, 102, 2122-2129.
7. Williamson, D.; Pikovski, I.; Cranmer, S.L.; Mangin, P.; Mistry, N.; Domagala, T.; Chehab, S.; Lanza, F.; Salem, H.H.; Jackson, S.P. Interaction between platelet glycoprotein Ibα and filamin-1 is essential for glycoprotein Ib/IX receptor anchorage at high shear. J. Biol. Chem. 2002, 277, 2151-2159.
8. Englund, G.D.; Bodnar, R.J.; Li, Z.; Ruggeri, Z.M.; Du, X. Regulationn of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal. J. Biol. Chem. 2001, 276, 16952-16959.
9. Okita, J.R.; Pidard, D.; Newman, P.J.; Montgomery, R.R.; Kunicki, T.J. On the association of glycoprotein Ib and actin-binding protein in human platelets. J. Cell Biol. 1985, 100, 317-321.
10. Andrew, R.K.; Munday, A.D.; Mitchell, C.A.; Berndt, M.C. Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. Blood 2001, 98, 681-687.
11. Mu, F.T.; Andrews, R.K.; Arthur, J.F.; Munday, A.D.; Cranmer, S.L.; Jackson, S.P.; Stomski, F.C.; Lopez, A.F.; Berndt, M.C. A functional 14-3-3ζ-independent association of PI3-kinase with glycoprotein Ibα, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-B complex. Blood 2008, 111, 4580-4587.
12. Dai, K.; Bodnar, R.; Berndt, M.C.; Du, X. A critical role for 14-3-3ζ protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood 2005, 106, 1975-1981.
13. Bodnar, R.J.; Xi, X.; Li, Z.; Berndt, M.C.; Du, X. Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ibβ. J. Biol. Chem. 2002, 277, 47080-47087.
14. Yuan, Y.; Zhang, W.; Yan, R.; Liao, Y.; Zhao, L.; Ruan, C.; Du, X.; Dai, K. Identification of a novel 14-3-3ζ binding site within the cytoplasmic domain of platelet glycoprotein Ibα that plays a key role in regulating the von Willebrand factor binding function of glycoprotein Ib-IX. Circ. Res. 2009, 105, 1177-1185.
15. Gu, M.; Xi, X.; Englund, G.D.; Berndt, M.C.; Du, X. Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin αIIbβ3 using a reconstituted mammalian cell expression model. J. Cell Biol. 1999, 147, 1085-1096.
16. Bialkowska, K.; Zaffran, Y.; Meyer, S.C.; Fox, J.E. 14-3-3ζ mediates integrin-induced activation of Cdc42 and Rac. J. Biol. Chem. 2003, 278, 33342-33350.
17. Zaffran, Y.; Meyer, S.C.; Negrescu, E.; Reddy, K.B.; Fox, J.E. Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces αIIbβ3 activation both in platelets and a transfected chinese hamster ovary cell system. J. Biol. Chem. 2000, 275, 16779-16787.
18. Wu, Y.; Asazuma, N.; Satoh, K.; Yakafuta, Y.; Berndt, M.C.; Ozaki, Y. Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: Role of phosphoinositide 3-kinase. Blood 2003, 101, 3469-3476.
19. Jackson, S.P.; Schoenwaelder, S.M.; Yuan, Y.; Rabinowitz, I.; Salem, H.H.; Mitchell, C.A. Adhesion receptor activation of phosphatidylinositol 3-kinase. Von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets. J. Biol. Chem. 1994, 269, 27093-27099.
20. Mazzucato, M.; Pradella, P.; Cozzi M.R.; de Marco, L.; Ruggeri, Z.M. Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibα mechanoreceptor. Blood 2002, 100, 2793-2800.
21. Li, S.; Wang, Z.; Liao, Y.; Zhang, W.; Shi, Q.; Yan, R.; Ruan, C.; Dai, K. The glycoprotein Ibα-von Willebrand factor interaction induces platelet apoptosis. J. Thromb. Haemost. 2010, 8, 341-350.
22. Mu, F.T.; Cranmer, S.L.; Andrews, R.K.; Berndt, M.C. Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibα, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex. J. Thromb. Haemost. 2010, 8, 324-330.
23. Ruan, C.G.; Xi, X.D.; Gu, J.M. Studies on monoclonal antibodies to human von Willebrand factor. Chung Hua Nei KoTsa Chih 1986, 25, 547-550, 576.
24. Ruan, C.G.; Du, X.P.; Xi, X.D.; Castaldi, P.A.; Berndt, M.C. A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen. Blood 1987, 69, 570-577.
25. Li, S.; Shi, Q.; Liu, G.; Zhang, W.; Wang, Z.; Wang, Y.; Dai, K. Mechanism of platelet functional changes and effects of anti-platelet agents on in vivo hemostasis under different gravity conditions. J. Appl. Physiol. 2010, 108, 1241-1249.