NETosis - does it really represent nature's "suicide bomber"?

Frontiers in Immunology

Volumn 7, Issue AUG, 2016, Pages

  Yousefi, Shida ^a   Simon, Hans Uwe ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Adaptive immunity; Cell death; Innate immunity; NETosis; Neutrophil extracellular traps

Indexed keywords

CITRULLINE;

ADAPTIVE IMMUNITY; APOPTOSIS; CONTROLLED STUDY; MICROBIAL COMMUNITY; NECROPTOSIS; NONHUMAN; NOTE; PHAGOCYTOSIS; PHYSIOLOGY; PUBLICATION; SIGNAL TRANSDUCTION;

EID: 84989318334     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2016.00328     Document Type: Note

References (35)

1. Fuchs TA, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol (2007) 176:231-41. doi:10.1083/jcb.200606027
2. Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ (2012) 19:107-20. doi:10.1038/cdd.2011.96
3. Amini P, Stojkov D, Wang X, Wicki S, Kaufmann T, Wong WWL, et al. NET formation can occur independently of RIPK3 and MLKL signaling. Eur J Immunol (2016) 46:178-84. doi:10.1002/eji.201545615
4. Yipp BG, Kubes P. NETosis: how vital is it? Blood (2013) 122:2784-94. doi:10.1182/blood-2013-04-457671
5. Conus S, Perozzo R, Reinheckel T, Peters C, Scapozza L, Yousefi S, et al. Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. J Exp Med (2008) 205:685-98. doi:10.1084/jem.20072152
6. Mihalache CC, Yousefi S, Conus S, Villiger PM, Schneider EM, Simon HU. Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events. J Immunol (2011) 186:6532-42. doi:10.4049/jimmunol.1004055
7. Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature (2010) 464:104-8. doi:10.1038/nature08780
8. Galluzzi L, Kepp O, Kroemer G. Mitochondria: master regulators of danger signaling. Nat Rev Mol Cell Biol (2012) 13:780-8. doi:10.1038/nrm3479
9. Wang H, Li T, Chen S, Gu Y, Ye S. Neutrophil extracellular trap mitochondrial DNA and its autoantibody in systemic lupus erythematosus and a proof-of-concept trial of metformin. Arthritis Rheum (2015) 67:3190-200. doi:10.1002/art.39296
10. Lood C, Blanco LP, Purmalek MM, Carmona-Rivera C, De Ravin SS, Smith CK, et al. Extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease. Nat Med (2016) 22:146-53. doi:10.1038/nm.4027
11. Caielli S, Athale A, Domic B, Murat E, Chandra M, Banchereau R, et al. Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus. J Exp Med (2016) 213:697-713. doi:10.1084/jem.20151876
12. Farrera C, Fadeel B. Macrophage clearance of neutrophil extracellular traps is a silent process. J Immunol (2013) 191:2647-56. doi:10.4049/jimmunol.1300436
13. Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, et al. Neutrophil extracellular traps kill bacteria. Science (2004) 303:1532-5. doi:10.1126/science.1092385
14. Losman MJ, Fasy TM, Novick KE, Monestier M. Monoclonal autoantibodies to subnucleosomes from a MRL/Mp(-)+/+ mouse. Oligoclonality of the antibody response and recognition of a determinant composed of histones H2A, H2B, and DNA. J Immunol (1992) 148:1561-9
15. Parseghian MH, Luhrs KA. Beyond the walls of the nucleus: the role of histones in cellular signaling and innate immunity. Biochem Cell Biol (2006) 84:589-604. doi:10.1139/o06-082
16. Darrah E, Rosen A, Giles JT, Andrade F. Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis. Ann Rheum Dis (2012) 71:92-8. doi:10.1136/ard.2011.151712
17. Spengler J, Lugonja B, Ytterberg AJ, Zubarev RA, Creese AJ, Pearson M, et al. Release of active peptidyl arginine deiminases by neutrophils can explain production of extracellular citrullinated autoantigens in rheumatoid arthritis synovial fluid. Arthritis Rheum (2015) 67:3135-45. doi:10.1002/art.39313
18. Wang S, Wang Y. Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis. Biochim Biophys Acta (2013) 1829:1126-35. doi:10.1016/j.bbagrm.2013.07.003
19. Maugeri N, Campana L, Gavina M, Covino C, De Metrio M, Panciroli C, et al. Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps. J Thromb Haemost (2014) 12:2074-88. doi:10.1111/jth.12710
20. Brill A, Fuchs TA, Aavchnko AS, Thomas GM, Martinod K, De Meyer SF, et al. Neutrophil extracellular traps promote deep vein thrombosis in mice. J Thromb Haemost (2012) 10:136-44. doi:10.1111/j.1538-7836.2011.04544.x
21. Vossenaar ER, Zendman AJW, van Venrooij WJ, Pruijn GJM. PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays (2003) 25:1106-18. doi:10.1002/bies.10357
22. Yousefi S, Mihalache C, Kozlowski E, Schmid I, Simon HU. Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps. Cell Death Differ (2009) 16:1438-44. doi:10.1038/cdd.2009.96
23. McIlroy DJ, Jarnicki AG, Au GG, Lott N, Smith DW, Hansbro PM, et al. Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery. J Crit Care (2014) 29:.e1-1133. doi:10.1016/j.jcrc.2014.07.013
24. Pilsczek FH, Salina D, Poon KKH, Fahey C, Yipp BG, Sibley CD, et al. A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus. J Immunol (2010) 185:7413-25. doi:10.4049/jimmunol.1000675
25. Aulik NA, Hellenbrand KM, Klos H, Czuprynski CJ. Mannheimia haemolytica and its leukotoxin cause neutrophil extracellular trap formation by bovine neutrophils. Infect Immun (2010) 78:4454-66. doi:10.1128/IAI.00840-10
26. Malachowa N, Kobayashi SD, Freedman B, Dorward DW, DeLeo FR. Staphylococcus aureus leukotoxin GH promotes formation of neutrophil extracellular traps. J Immunol (2013) 191:6022-9. doi:10.4049/jimmunol.1301821
27. Brinkmann V, Zychlinsky A. Neutrophil extracellular traps: is immunity the second function of chromatin? J Cell Biol (2012) 198:773-83. doi:10.1083/jcb.201203170
28. Papayannopoulos V, Metzler KD, Hakkim A, Zychlinsky A. Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J Cell Biol (2010) 191:677-91. doi:10.1083/jcb.201006052
29. Martinod K, Witsch T, Farley K, Gallant M, Remold-O'Donnell E, Wagner DD. Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis. J Thromb Haemost (2016) 14:551-8. doi:10.1111/jth.13239
30. Desai J, Kumar SV, Mulay SR, Konrad L, Romoli S, Schauer C, et al. Neutrophil extracellular trap formation can involve RIPK1-RIPK3-MLKL signalling. Eur J Immunol (2016) 46:223-9. doi:10.1002/eji.201545605
31. Cools-Lartigue J, Spicer J, McDonald B, Gowing S, Chow S, Giannias B, et al. Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. J Clin Invest (2013) 123:3446-58. doi:10.1172/JCI67484
32. Ermert D, Urban CF, Laube B, Goosmann C, Zychlinsky A, Brinkmann V. Mouse neutrophil extracellular traps in microbial infections. J Innate Immun (2009) 1:181-93. doi:10.1159/000205281
33. Takei H, Araki A, Watanabe H, Lchinose A, Sendo F. Rapid killing of human neutrophils by the potent activator phorbol 12-myristate 1 3-acetate (PMA) accompanied by changes different from typical apoptosis or necrosis. J Leukoc Biol (1996) 59:229-40
34. Yousefi S, Gold JA, Andina N, Lee JJ, Kelly AM, Kozlowski E, et al. Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nat Med (2008) 14:949-53. doi:10.1038/nm.1855
35. Morshed M, Hlushchuk R, Simon D, Walls AF, Obata-Ninomiya K, Karasuyama H, et al. NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol (2014) 192:5314-23. doi:10.4049/jimmunol.1303418