PERK Regulates working memory and protein synthesis-dependent memory flexibility

PLoS ONE

Volumn 11, Issue 9, 2016, Pages

  Zhu, Siying ^a   Henninger, Keely ^a   McGrath, Barbara C ^a   Cavener, Douglas R ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYL 5 [1 [[3 (TRIFLUOROMETHYL)PHENYL]ACETYL] 2,3 DIHYDRO 1H INDOL 5 YL] 7H P YRROLO[2,3 D]PYRIMIDIN 4 AMINE; CALCIUM ION; PERK PROTEIN; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG; 7-METHYL-5-(1-((3-(TRIFLUOROMETHYL)PHENYL)ACETYL)-2,3-DIHYDRO-1H-INDOL-5-YL)-7H-PYRROLO(2,3-D)PYRIMIDIN-4-AMINE; ADENINE; INDOLE DERIVATIVE; NERVE PROTEIN; PERK KINASE; PROTEIN KINASE R;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; CALCIUM CELL LEVEL; CEREBELLUM; COGNITION; CONTROLLED STUDY; FEAR; FOREBRAIN; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMORY DISORDER; MEMORY TEST; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PROTEIN FUNCTION; PROTEIN SYNTHESIS; WORKING MEMORY; Y-MAZE TEST; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; KNOCKOUT MOUSE; MAZE TEST; METABOLISM; PHYSIOLOGY; REINFORCEMENT; SHORT TERM MEMORY; WESTERN BLOTTING;

ADENINE; ANIMALS; BLOTTING, WESTERN; EIF-2 KINASE; EXTINCTION, PSYCHOLOGICAL; INDOLES; MAZE LEARNING; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; PROSENCEPHALON;

EID: 84989210846     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0162766     Document Type: Article

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