eIF4B stimulates translation of long mRNAs with structured 5′ UTRs and low closed-loop potential but weak dependence on eIF4G

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 38, 2016, Pages 10464-10472

  Sen, Neelam Dabas ^a   Zhou, Fujun ^a   Harris, Michael S ^b,c   Ingolia, Nicholas T ^b,c   Hinnebusch, Alan G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Ded1; eIF4A; eIF4B; eIF4G; Translation

Indexed keywords

INITIATION FACTOR 4A; INITIATION FACTOR 4B; INITIATION FACTOR 4G; MESSENGER RNA; POLYADENYLIC ACID BINDING PROTEIN; DEAD BOX PROTEIN; DED1 PROTEIN, S CEREVISIAE; EIF-4B; INITIATION FACTOR; INITIATION FACTOR 4F; PAB1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

5' UNTRANSLATED REGION; ALLELE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FUNGAL STRAIN; IN VIVO STUDY; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SECONDARY STRUCTURE; RIBOSOME; RNA STRUCTURE; START CODON; TRANSLATION INITIATION; CONFORMATION; GENETICS; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE;

5' UNTRANSLATED REGIONS; DEAD-BOX RNA HELICASES; EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4F; EUKARYOTIC INITIATION FACTOR-4G; EUKARYOTIC INITIATION FACTORS; NUCLEIC ACID CONFORMATION; POLY(A)-BINDING PROTEINS; PROTEIN BIOSYNTHESIS; RIBOSOMES; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84988930273     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1612398113     Document Type: Article

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