Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation

Science

Volumn 353, Issue 6307, 2016, Pages 1549-1552

  Kanakkanthara, Arun ^a   Jeganathan, Karthik B ^a   Limzerwala, Jazeel F ^b   Baker, Darren J ^a   Hamada, Masakazu ^a   Nam, Hyun Ja ^a   Van Deursen, Willemijn H ^a   Hamada, Naomi ^a   Naylor, Ryan M ^b   Becker, Nicole A ^b   Davies, Brian A ^b   Van Ree, Janine H ^a   Mer, Georges ^b   Shapiro, Virginia S ^b   Maher, L James ^b   Katzmann, David J ^b   Van Deursen, Jan M ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; COHESIN; CYCLIN A2; CYCLIN DEPENDENT KINASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; HEMAGGLUTININ; HISTONE H2AX; INITIATION FACTOR 4A; MESSENGER RNA; MOLECULAR MOTOR; MOTOR PROTEIN EG5; MRE11 PROTEIN; NIBRIN; PROTEIN; RAD50 PROTEIN; RNA BINDING PROTEIN; RPA2 PROTEIN; SINGLE STRANDED DNA; TRANSLATION INITIATION FACTOR EIF4A2; UNCLASSIFIED DRUG; CCNA2 PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE 1; DNA BINDING PROTEIN; DNA LIGASE; EG5 PROTEIN, MOUSE; KINESIN; MRE11A PROTEIN, MOUSE;

CHROMOSOME; EXPERIMENTAL STUDY; GENE EXPRESSION; GENETIC ANALYSIS; PROTEIN; REACTION KINETICS; RECOMBINATION; RNA; RODENT;

3' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ANEUPLOIDY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CENTROSOME; CHROMOSOMAL INSTABILITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; ECTOPIC EXPRESSION; EMBRYO DEVELOPMENT; FEMALE; HUMAN; HUMAN CELL; MEIOTIC RECOMBINATION; MITOSIS INDEX; MITOSIS SPINDLE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROPHASE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN RNA BINDING; RNA SEQUENCE; TRANSLATION REGULATION; UPREGULATION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; MEIOSIS; METABOLISM; MITOSIS; MUTANT MOUSE STRAIN; PROTEIN SYNTHESIS;

MUS;

ANIMALS; CDC2 PROTEIN KINASE; CENTROSOME; CHROMOSOMAL INSTABILITY; CYCLIN A2; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPAIR ENZYMES; DNA REPLICATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; KINESIN; MEIOSIS; MICE; MICE, MUTANT STRAINS; MITOSIS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; RNA-BINDING PROTEINS; S PHASE;

EID: 84988929188     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf7463     Document Type: Article

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