Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy

Nature Genetics

Volumn 48, Issue 11, 2016, Pages 1327-1329

  Riaz, Nadeem ^a   Havel, Jonathan J ^a   Kendall, Sviatoslav M ^a   Makarov, Vladimir ^a   Walsh, Logan A ^a   Desrichard, Alexis ^a   Weinhold, Nils ^a   Chan, Timothy A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; OVALBUMIN; PROTEIN; SERPINB3 PROTEIN; SERPINB4 PROTEIN; UNCLASSIFIED DRUG; IPILIMUMAB; MONOCLONAL ANTIBODY; SERINE PROTEINASE INHIBITOR; SQUAMOUS CELL CARCINOMA-RELATED ANTIGEN; TUMOR ANTIGEN;

ARTICLE; AUTOIMMUNITY; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; EXOME; GENE; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOTHERAPY; MAJOR CLINICAL STUDY; MELANOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; SERPINB3 GENE; SERPINB4 GENE; SOMATIC MUTATION; COHORT ANALYSIS; GENETICS; MUTATION; SURVIVAL ANALYSIS;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; COHORT STUDIES; HUMANS; MELANOMA; MUTATION; SERPINS; SURVIVAL ANALYSIS;

EID: 84988734918     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3677     Document Type: Article

References (37)

1. Hodi, F.S. et al. N. Engl. J. Med. 363, 711-723 (2010).
2. Robert, C. et al. N. Engl. J. Med. 364, 2517-2526 (2011).
3. Brahmer, J. et al. N. Engl. J. Med. 373, 123-135 (2015).
4. Motzer, R.J. et al. N. Engl. J. Med. 373, 1803-1813 (2015).
5. Robert, C. et al. N. Engl. J. Med. 372, 320-330 (2015).
6. Snyder, A. et al. N. Engl. J. Med. 371, 2189-2199 (2014).
7. Rizvi, N.A. et al. Science 348, 124-128 (2015).
8. Le, D.T. et al. N. Engl. J. Med. 372, 2509-2520 (2015).
9. Van Allen, E.M. et al. Science 350, 207-211 (2015).
10. McGranahan, N. et al. Science 351, 1463-1469 (2016).
11. Cancer Genome Atlas Network. Cell 161, 1681-1696 (2015).
12. Vidalino, L. et al. Autoimmun. Rev. 9, 108-112 (2009).
13. Gatto, M. et al. Clin. Rev. Allergy Immunol. 45, 267-280 (2013).
14. Sivaprasad, U. et al. J. Invest. Dermatol. 135, 160-169 (2015).
15. Schneider, S.S. et al. Proc. Natl. Acad. Sci. USA 92, 3147-3151 (1995).
16. Catanzaro, J.M. et al. Nat. Commun. 5, 3729 (2014).
17. Guan, J., Gupta, R. & Filipp, F.V. Sci. Rep. 5, 7857 (2015).
18. Katagiri, C., Nakanishi, J., Kadoya, K. & Hibino, T. J. Cell Biol. 172, 983-990 (2006).
19. El-Rachkidy, R.G., Young, H.S., Griffths, C.E. & Camp, R.D. J. Invest. Dermatol. 128, 2219-2224 (2008).
20. Lysvand, H., Hagen, L., Klubicka, L., Slupphaug, G. & Iversen, O.J. Biochim. Biophys. Acta 1842, 734-738 (2014).
21. Münz, C. Front. Immunol. 3, 9 (2012).
22. Schumacher, T. et al. Nature 512, 324-327 (2014).
23. Mine, Y. & Yang, M. J. Agric. Food Chem. 56, 4874-4900 (2008).
24. Holen, E. & Elsayed, S. Clin. Exp. Allergy 26, 1080-1088 (1996).
25. DePristo, M.A. et al. Nat. Genet. 43, 491-498 (2011).
26. Li, H. & Durbin, R. Bioinformatics 25, 1754-1760 (2009).
27. McKenna, A. et al. Genome Res. 20, 1297-1303 (2010).
28. Cibulskis, K. et al. Nat. Biotechnol. 31, 213-219 (2013).
29. Koboldt, D.C. et al. Genome Res. 22, 568-576 (2012).
30. Larson, D.E. et al. Bioinformatics 28, 311-317 (2012).
31. Saunders, C.T. et al. Bioinformatics 28, 1811-1817 (2012).
32. Strona, G., Nappo, D., Boccacci, F. , Fattorini, S. & San-Miguel-Ayanz, J. Nat. Commun. 5, 4114 (2014).
33. Kim, J. et al. Nat. Genet. 48, 600-606 (2016).
34. Schellens, I.M. et al. PLoS One 10, e0136417 (2015).
35. Snyder, A. & Chan, T.A. Curr. Opin. Genet. Dev. 30, 7-16 (2015).
36. Nielsen, M. et al. Protein Sci. 12, 1007-1017 (2003).
37. Andreatta, M. et al. Immunogenetics 67, 641-650 (2015).