Graphene based scaffolds effects on stem cells commitment

Journal of Translational Medicine

Volumn 12, Issue 1, 2014, Pages

  Bressan, Eriberto ^a   Ferroni, Letizia ^a   Gardin, Chiara ^a   Sbricoli, Luca ^a   Gobbato, Luca ^a   Ludovichetti, Francesco Saverio ^a   Tocco, Ilaria ^b   Carraro, Amedeo ^c   Piattelli, Adriano ^d   Zavan, Barbara ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^c UNIVERSITY HOSPITAL OF VERONA   (Italy)

^d UNIVERSITY OF CHIETI   (Italy)

Author keywords

Adipogenic differentiation; Graphene; Neuronal differentiation; Oosteogenic differentiation; Stem cells; Tissue engineering

Indexed keywords

CARBON NANOPARTICLE; GRAPHENE; GRAPHITE;

ADIPOGENIC CELL; BIOCOMPATIBILITY; CARDIAC MUSCLE CELL; CELL DIFFERENTIATION; CELL LINEAGE; CELLS BY BODY ANATOMY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; EPITHELIAL MESENCHYMAL TRANSITION; INDUCED PLURIPOTENT STEM CELL; NERVE CELL; OSTEOBLAST; PERIODONTAL LIGAMENT; REGENERATIVE MEDICINE; REVIEW; STEM CELL; TISSUE ENGINEERING; TISSUE SCAFFOLD; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; HUMAN;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; GRAPHITE; HUMANS; STEM CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84988603070     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-014-0296-9     Document Type: Review

References (52)

1. Bressan E, Carraro A, Ferroni L, Gardin C, Sbricoli L, Guazzo R, Stellini E, Roman M, Pinton P, Sivolella S, Zavan B: Nanotechnology to drive stem cell commitment. Nanomedicine (Lond) 2013, 8:469-486.
2. McMurray RJ, Gadegaard N, Tsimbouri PM, Burgess KV, McNamara LE, Tare R, Murawski K, Kingham E, Oreffo RO, Dalby MJ: Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nat Mater 2011, 10:637-644.
3. Nayak TR, Andersen H, Makam VS, Khaw C, Bae S, Xu X, Ee PL, Ahn JH, Hong BH, Pastorin G, Özyilmaz B: Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells. ACS Nano 2011, 5:4670-4678.
4. Reilly GC, Engler AJ: Intrinsic extracellular matrix properties regulate stem cell differentiation. J Biomech 2010, 43:55-62.
5. Engler AJ, Sen S, Sweeney HL, Discher DE: Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
6. Discher DE, Mooney DJ, Zandstra PW: Growth factors, matrices, and forces combine and control stem cells. Science 2009, 324:1673-1677.
7. Spradling A, Drummond-Barbosa D, Kai T: Stem cells find their niche. Nature 2001, 414:98-104.
8. Novoselov KS, Geim AK, Morozov SV, Jiang D, Zhang Y, Dubonos SV, Grigorieva IV, Firsov AA: Electric field effect in atomically thin carbon films. Science 2004, 306:666-669.
9. Chen GY, Pang DW, Hwang SM, Tuan HY, Hu YC: A graphene-based platform for induced pluripotent stem cells culture and differentiation. Biomaterials 2012, 33:418-427.
10. Mimeault M, Batra SK: Great promise of tissue-resident adult stem/progenitor cells in transplantation and cancer therapies. Adv Exp Med Biol 2012, 741:171-186.
11. Kim J, Choi KS, Kim Y, Lim KT, Seonwoo H, Park Y, Kim DH, Choung PH, Cho CS, Kim SY, Choung YH, Chung JH: Bioactive effects of graphene oxide cell culture substratum on structure and function of human adipose-derived stem cells. J Biomed Mater Res A 2013, 101:3520-3530.
12. Mooney E, Dockery P, Greiser U, Murphy M, Barron V: Carbon nanotubes and mesenchymal stem cells: biocompatibility, proliferation and differentiation. Nano Lett 2008, 8:2137-2143.
13. Lee WC, Lim CH, Shi H, Tang LA, Wang Y, Lim CT, Loh KP: Origin of enhanced stem cell growth and differentiation on graphene and graphene oxide. ACS Nano 2011, 5:7334-7341.
14. La WG, Park S, Yoon HH, Jeong GJ, Lee TJ, Bhang SH, Han JY, Char K, Kim BS: Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide. Small 2013, 9:4051-4060.
15. Jastrzebska AM, Kurtycz P, Olszyna AR: Recent advances in graphene family materials toxicity investigations. J Nanopart Res 2012, 14:1320.
16. Kim KS, Zhao Y, Jang H, Lee SY, Kim JM, Kim KS, Ahn JH, Kim P, Choi JY, Hong BH: Large-scale pattern growth of graphene films for stretchable transparent electrodes. Nature 2009, 457:706-710.
17. Sanchez VC, Jachak A, Hurt RH, Kane AB: Biological interactions of graphene-family nanomaterials: an interdisciplinary review. Chem Res Toxicol 2012, 25:15-34.
18. Ku SH, Park CB: Myoblast differentiation on graphene oxide. Biomaterials 2013, 34:2017-2023.
19. Park SY, Park J, Sim SH, Sung MG, Kim KS, Hong BH, Hong S: Enhanced differentiation of human neural stem cells into neurons on graphene. Adv Mater 2011, 23:H263-267.
20. Gu M, Liu Y, Chen T, Du F, Zhao X, Xiong C, Zhou Y: Is graphene a promising nano-material for promoting surface modification of implants or scaffold materials in bone tissue engineering? Tissue Eng Part B Rev 2014, 20:477-491.
21. Kalbacova M, Broz A, Kong J, Kalbac M: Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells. Carbon 2010, 48:4323-4329.
22. Crowder SW, Prasai D, Rath R, Balikov DA, Bae H, Bolotin KI, Sung HJ: Threedimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells. Nanoscale 2013, 5:4171-4176.
23. Duan S, Yang X, Mei F, Tang Y, Li X, Shi Y, Mao J, Zhang H, Cai Q: Enhanced osteogenic differentiation of mesenchymal stem cells on poly(l-lactide) nanofibrous scaffolds containing carbon nanomaterials. J Biomed Mater Res A 2014, in press.
24. Tatavarty R, Ding H, Lu G, Taylor RJ, Bi X: Synergistic acceleration in the osteogenesis of human mesenchymal stem cells by graphene oxide-calcium phosphate nanocomposites. Chem Commun (Camb) 2014, 50:8484-8487.
25. Xie Y, Li H, Zhang C, Gu X, Zheng X, Huang L: Graphene-reinforced calcium silicate coatings for load-bearing implants. Biomed Mater 2014, 9:025009.
26. Orive G, Anitua E, Pedraz JL, Emerich DF: Biomaterials for promoting brain protection, repair and regeneration. Nat Rev Neurosci 2009, 10:682-692.
27. Li N, Zhang Q, Gao S, Song Q, Huang R, Wang L, Liu L, Dai J, Tang M, Cheng G: Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells. Sci Rep 2013, 3:1604.
28. Hong SW, Lee JH, Kang SH, Hwang EY, Hwang YS, Lee MH, Han DW, Park JC: Enhanced neural cell adhesion and neurite outgrowth on graphene-based biomimetic substrates. Biomed Res Int 2014, 2014:212149.
29. Wang Y, Lee WC, Manga KK, Ang PK, Lu J, Liu YP, Lim CT, Loh KP: Fluorinated graphene for promoting neuro-induction of stem cells. Adv Mater 2012, 24:4285-4290.
30. Li X, Macewan MR, Xie J Dr, Siewe D, Yuan X, Xia Y: Fabrication of Density Gradients of Biodegradable Polymer Microparticles and Their Use in Guiding Neurite Outgrowth. Adv Funct Mater 2010, 20:1632-1637.
31. Chang KA, Kim JW, Kim JA, Lee SE, Kim S, Suh WH, Kim HS, Kwon S, Kim SJ, Suh YH: Biphasic electrical currents stimulation promotes both proliferation and differentiation of fetal neural stem cells. PLoS One 2011, 6:e18738.
32. Yang D, Li T, Xu M, Gao F, Yang J, Yang Z, Le W: Graphene oxide promotes the differentiation of mouse embryonic stem cells to dopamine neurons. Nanomedicine (Lond) 2014, doi:10.2217/nnm.13.197
33. Tang M, Song Q, Li N, Jiang Z, Huang R, Cheng G: Enhancement of electrical signaling in neural networks on graphene films. Biomaterials 2013, 34:6402-6411.
34. Akhavan O, Ghaderi E: Flash photo stimulation of human neural stem cells on graphene/TiO2 heterojunction for differentiation into neurons. Nanoscale 2013, 5:10316-10326.
35. Shah S, Yin PT, Uehara TM, Chueng ST, Yang L, Lee KB: Guiding stem cell differentiation into oligodendrocytes using graphene-nanofiber hybrid scaffolds. Adv Mater 2014, 11:3673-3680.
36. Yang D, Li T, Xu M, Gao F, Yang J, Yang Z, Le W: Graphene oxide promotes the differentiation of mouse embryonic stem cells to dopamine neurons. Nanomedicine (Lond) 2014, in press.
37. Song Q, Jiang Z, Li N, Liu P, Liu L, Tang M, Cheng G: Anti-inflammatory effects of three-dimensional graphene foams cultured with microglial cells. Biomaterials 2014, 35:6930-6940.
38. Li N, Zhang X, Song Q, Su R, Zhang Q, Kong T: The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates. Biomaterials 2011, 32:9374-9382.
39. Rodríguez-Lozano FJ, García-Bernal D, Aznar-Cervantes S, Ros-Roca MA, Algueró MC, Atucha NM, Lozano-García AA, Moraleda JM, Cenis JL: Effects of composite films of silk fibroin and graphene oxide on the proliferation, cell viability and mesenchymal phenotype of periodontal ligament stem cells. J Mater Sci Mater Med. 2014, in press.
40. Lee TJ, Park S, Bhang SH, Yoon JK, Jo I, Jeong GJ, Hong BH, Kim BS: Graphene enhances the cardiomyogenic differentiation of human embryonic stem cells. Biochem Biophys Res Commun 2014, 12:174-180.
41. Park J, Park S, Ryu S, Bhang SH, Kim J, Yoon JK, Park YH, Cho SP, Lee S, Hong BH, Kim BS: Graphene-regulated cardiomyogenic differentiation process of mesenchymal stem cells by enhancing the expression of extracellular matrix proteins and cell signaling molecules. Biomaterials 2014, 35:4863-4877.
42. Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
43. Yoo J, Kim J, Baek S, Park Y, Im H, Kim J: Cell reprogramming into the pluripotent state using graphene based substrates. Biomaterials 2014, 35:8321-8329.
44. Talukdar Y, Rashkow JT, Lalwani G, Kanakia S, Sitharaman B: The effects of graphene nanostructures on mesenchymal stem cells. Biomaterials 2014, 35:4863-4877.
45. Zhang M, Bai L, Shang W, Xie W, Ma H, Fu Y: Facile synthesis of watersoluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells. J Mater Chem 2012, 22:7461e7.
46. Akhavan O, Ghaderi E, Akhavan A: Size-dependent genotoxicity of graphene nanoplatelets in human stem cells. Biomaterials 2012, 33:8017-8025.
47. Chen C, Dubin R, Kim MC: Emerging trends and new developments in regenerative medicine: a scientometric update (2000-2014). Expert Opin Biol Ther 2014, 14:1295-1317.
48. Nel AE, Madler L, Velegol D, Xia T, Hoek EM, Somasundaran P, Klaessig F, Castranova V, Thompson M: Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 2009, 8:543-557.
49. Chang Y, Yang ST, Liu JH, Dong E, Wang Y, Cao A, Liu Y, Wang H: In vitro toxicity evaluation of graphene oxide on A549 cells. Toxicol Lett 2011, 200:201-210.
50. Sanchez VC, Jachak A, Hurt RH, Kane AB: Biological interactions of graphene-family nanomaterials: an interdisciplinary review. Chem Res Toxicol 2012, 13:15-34.
51. Yang X, Wang Y, Huang X, Ma Y, Huang Y, Yang R, Duana H, Chen Y: Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity. J Mater Chem 2010, 21:3448-3454.
52. Zhang Y, Ali SF, Dervishi E, Xu Y, Li Z, Casciano D, Biris AS: Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells. ACS Nano 2010, 4:3181-3186.