Graphene oxide promotes the differentiation of mouse embryonic stem cells to dopamine neurons

Nanomedicine

Volumn 9, Issue 16, 2014, Pages 2445-2455

  Yang, Dehua ^a,c   Li, Ting ^a   Xu, Minghan ^b   Gao, Feng ^b   Yang, Juan ^a   Yang, Zhi ^b   Le, Weidong ^a,d  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Jiao Tong University   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^d DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

carbon nanotubes; differentiation; dopamine neurons; embryonic stem cells; graphene; graphene oxide

Indexed keywords

ASCORBIC ACID; CARBON NANOTUBE; CARBOXYLIC ACID; GRAPHENE; GRAPHENE OXIDE; NITROGEN; SUCCINATE DEHYDROGENASE; GRAPHITE; OXIDE;

ANIMAL CELL; ARTICLE; BRIGHT FIELD MICROSCOPY; CELL ADHESION; CELL COUNT; CHEMICAL ANALYSIS; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; FIBROBLAST; FLUORESCENCE; GENE EXPRESSION; HYDROGEN BOND; HYDROPHILICITY; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; INFRARED SPECTROSCOPY; MITOCHONDRION; MOUSE; MRNA EXPRESSION ASSAY; MTT ASSAY; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA CELL; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; STEM CELL; STEM CELL CULTURE; UPREGULATION; VAPOR; ANIMAL; CELL DIFFERENTIATION; CHEMISTRY; DRUG EFFECTS;

ANIMALS; CELL DIFFERENTIATION; DOPAMINERGIC NEURONS; EMBRYONIC STEM CELLS; GRAPHITE; MICE; NANOTUBES, CARBON; OXIDES;

EID: 84918508852     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.13.197     Document Type: Article

References (35)

1. Olanow CW, Tatton WG. Etiology and pathogenesis of Parkinson's disease. Annu. Rev. Neurosci. 22, 123-144 (1999).
2. Le W, Shen C, Jankovic J. Etiopathogenesis of Parkinson disease: a new beginning? Neuroscientist 15 (1), 28-35 (2009).
3. Bjorklund A, Dunnett SB. Dopamine neuron systems in the brain: an update. Trends Neurosci. 30(5), 194-202 (2007).
4. Roy NS, Cleren C, Singh SK, Yang L, Beal MF, Goldman SA. Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat. Med. 12(11), 1259-1268 (2006).
5. Prakash N, Wurst W. Genetic networks controlling the development of midbrain dopaminergic neurons. J. Physiol. 575(Pt 2), 403-410 (2006).
6. Xia Y. Nanomaterials at work in biomedical research. Nat. Mater. 7(10), 758-760 (2008).
7. Zhao C, Tan A, Pastorin G, Ho HK. Nanomaterial scaffolds for stem cell proliferation and differentiation in tissue engineering. Biotechnol. Adv. 31(5), 654-668 (2012).
8. Ferreira L. Nanoparticles as tools to study and control stem cells. J. Cell. Biochem. 108(4), 746-752 (2009).
9. Ferreira L, Karp JM, Nobre L, Langer R. New opportunities: the use of nanotechnologies to manipulate and track stem cells. Cell Stem Cell 3(2), 136-146 (2008).
10. Nel AE, Madler L, Velegol D et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 8(7), 543-557 (2009).
11. Yi C, Liu D, Fong CC, Zhang J, Yang M. Gold nanoparticles promote osteogenic differentiation of mesenchymal stem cells through p38 MAPK pathway. ACS Nano 4(11), 6439-6448 (2010).
12. Ilie I, Ilie R, Mocan T, Bartos D, Mocan L. Infuence of nanomaterials on stem cell differentiation: designing an appropriate nanobiointerface. Int. J. Nanomedicine 7, 2211-2225 (2012).
13. Mooney E, Dockery P, Greiser U, Murphy M, Barron V. Carbon nanotubes and mesenchymal stem cells: bio compatibility, proliferation and differentiation. Nano Lett. 8(8), 2137-2143 (2008).
14. Kostarelos K, Lacerda L, Pastorin G et al. Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. Nat. Nanotechnol. 2(2), 108-113 (2007).
15. Nayak TR, Jian L, Phua LC, Ho HK, Ren Y, Pastorin G. Thin flms of functionalized multiwalled carbon nanotubes as suitable scaffold materials for stem cells proliferation and bone formation. ACS Nano 4(12), 7717-7725 (2010).
16. Li X, Wang X, Zhang L, Lee S, Dai H. Chemically derived, ultrasmooth graphene nanoribbon semiconductors. Science 319(5867), 1229-1232 (2008).
17. Stankovich S, Dikin DA, Dommett GH et al. Graphene-based composite materials. Nature 442(7100), 282-286 (2006).
18. Ueno Y, Furukawa K, Hayashi K, Takamura M, Hibino H, Tamechika E. Graphene-modifed inter digitated array electrode: fabrication, characterization, and electrochemical immunoassay application. Anal. Sci. 29(1), 55-60 (2013).
19. Gurunathan S, Han JW, Eppakayala V, Kim JH. Biocompatibility of microbially reduced graphene oxide in primary mouse embryonic fbroblast cells. Colloids Surf. B Biointerfaces 105C, 58-66 (2013).
20. Lee WC, Lim CH, Shi H et al. Origin of enhanced stem cell growth and differentiation on graphene and graphene oxide. ACS Nano 5(9), 7334-7341 (2011).
21. Park SY, Park J, Sim SH et al. Enhanced differentiation of human neural stem cells into neurons on graphene. Adv. Mater. 23(36), H263-267 (2011).
22. Nayak TR, Andersen H, Makam VS et al. Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells. ACS Nano 5(6), 4670-4678 (2011).
23. Chen GY, Pang DW, Hwang SM, Tuan HY, Hu YC. A graphene-based platform for induced pluripotent stem cells culture and differentiation. Biomaterials 33(2), 418-427 (2012).
24. Lv M, Zhang Y, Liang L et al. Effect of graphene oxide on undifferentiated and retinoic acid-differentiated SH-SY5Y cells line. Nanoscale 4(13), 3861-3816 (2012).
25. Sun X, Liu Z, Welsher K et al. Nano-graphene oxide for cellular imaging and drug delivery. Nano Res. 1(3), 203-212 (2008).
26. Yang D, Li T, Wang Y et al. miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression. J. Cell. Sci. 125(Pt 7), 1673-1682 (2012).
27. Hummers WS, Offerman RE. Preparation of graphitic oxide. J. Am. Chem. Soc. 80(6), 1339-1339 (1958).
28. Hu N, Gao R, Wang Y et al. The preparation and characterization of non-covalently function a li zed graphene. J. Nanosci. Nanotechnol. 12(1), 99-104 (2012).
29. Gao R, Hu N, Yang Z et al. Paper-like graphene-Ag composite flms with enhanced mechanical and electrical properties. Nanoscale Res. Lett. 8(1), 32 (2013).
30. Zhang J, Yang H, Shen G, Cheng P, Zhang J, Guo S. Reduction of graphene oxide via L-ascorbic acid. Chem. Commun. (Camb.) 46(7), 1112-1114 (2010).
31. Ying QL, Stavridis M, Griffths D, Li M, Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat. Biotechnol. 21(2), 183-186 (2003).
32. Kawasaki H, Mizuseki K, Nishikawa S et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28(1), 31-40 (2000).
33. Yoshizaki T, Inaji M, Kouike H et al. Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells. Neurosci. Lett. 363(1), 33-37 (2004).
34. Hedlund E, Pruszak J, Ferree A et al. Selection of embryonic stem cell-derived enhanced green fuorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations. Stem Cells 25(5), 1126-1135 (2007).
35. Kang W, Ruan J, Song H et al. Bio compatibility of graphene oxide. Nanoscale Res. Lett. 6, 8 (2011).