-
1
-
-
44349150012
-
Inhibitory B7-family molecules in the tumour microenvironment
-
Zou W, Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol 2008; 8: 467-477.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 467-477
-
-
Zou, W.1
Chen, L.2
-
2
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN,Wang H, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med 2015; 372: 2509-2520.
-
(2015)
N Engl J Med
, vol.372
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
-
3
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12: 252-264.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
4
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn GP, Bruce AT, Ikeda H, et al. Cancer immunoediting: From immunosurveillance to tumor escape. Nat Immunol 2002; 3: 991-998.
-
(2002)
Nat Immunol
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
-
5
-
-
0035056185
-
In vivo activation of antigen-specific CD4 T cells
-
Jenkins MK, Khoruts A, Ingulli E, et al. In vivo activation of antigen-specific CD4 T cells. Annu Rev Immunol 2001; 19: 23-45.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 23-45
-
-
Jenkins, M.K.1
Khoruts, A.2
Ingulli, E.3
-
6
-
-
0033563265
-
Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses
-
Khattri R, Auger JA, Griffin MD, et al. Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses. J Immunol 1999; 162: 5784-5791.
-
(1999)
J Immunol
, vol.162
, pp. 5784-5791
-
-
Khattri, R.1
Auger, J.A.2
Griffin, M.D.3
-
7
-
-
55949083407
-
Anticytotoxic T-lymphocyte antigen-4 antibody: The first in an emerging class of immunomodulatory antibodies for cancer treatment
-
Fong L, Small EJ. Anticytotoxic T-lymphocyte antigen-4 antibody: The first in an emerging class of immunomodulatory antibodies for cancer treatment. J Clin Oncol 2008; 26: 5275-5283.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5275-5283
-
-
Fong, L.1
Small, E.J.2
-
8
-
-
84933678156
-
Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): A randomised, double-blind, phase 3 trial
-
Eggermont AM, Chiarion-Sileni V, Grob JJ, et al. Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): A randomised, double-blind, phase 3 trial. Lancet Oncol 2015; 16: 522-530.
-
(2015)
Lancet Oncol
, vol.16
, pp. 522-530
-
-
Eggermont, A.M.1
Chiarion-Sileni, V.2
Grob, J.J.3
-
9
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
10
-
-
77955256254
-
Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: A multicenter single-arm phase II study
-
O'Day SJ, Maio M, Chiarion-Sileni V, et al. Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: A multicenter single-arm phase II study. Ann Oncol 2010; 21: 1712-1717.
-
(2010)
Ann Oncol
, vol.21
, pp. 1712-1717
-
-
O'Day, S.J.1
Maio, M.2
Chiarion-Sileni, V.3
-
11
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial
-
Weber JS, D'Angelo SP, Minor D, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial. Lancet Oncol 2015; 16: 375-384.
-
(2015)
Lancet Oncol
, vol.16
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
-
12
-
-
84890288009
-
Immune-mediated adverse events associated with ipilimumab CTLA-4 blockade therapy: The underlying mechanisms and clinical management
-
Tarhini A. Immune-mediated adverse events associated with ipilimumab CTLA-4 blockade therapy: The underlying mechanisms and clinical management. Scientifica (Cairo) 2013; 2013: 857519.
-
(2013)
Scientifica (Cairo)
, vol.2013
, pp. 857519
-
-
Tarhini, A.1
-
13
-
-
80955130103
-
Safety and clinical activity of ipilimumab in melanoma patients with brain metastases: Retrospective analysis of data from a phase 2 trial
-
Weber JS, Amin A, Minor D, et al. Safety and clinical activity of ipilimumab in melanoma patients with brain metastases: Retrospective analysis of data from a phase 2 trial. Melanoma Res 2011; 21: 530-534.
-
(2011)
Melanoma Res
, vol.21
, pp. 530-534
-
-
Weber, J.S.1
Amin, A.2
Minor, D.3
-
14
-
-
84876248304
-
Endocrine side effects induced by immune checkpoint inhibitors
-
Corsello SM, Barnabei A, Marchetti P, et al. Endocrine side effects induced by immune checkpoint inhibitors. J Clin Endocrinol Metab 2013; 98: 1361-1375.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 1361-1375
-
-
Corsello, S.M.1
Barnabei, A.2
Marchetti, P.3
-
15
-
-
84922738416
-
Peripheral neuropathy associated with ipilimumab: A report of 2 cases
-
Thaipisuttikul I, Chapman P, Avila EK. Peripheral neuropathy associated with ipilimumab: A report of 2 cases. J Immunother 2015; 38: 77-79.
-
(2015)
J Immunother
, vol.38
, pp. 77-79
-
-
Thaipisuttikul, I.1
Chapman, P.2
Avila, E.K.3
-
16
-
-
79953300714
-
Anti-CTLA-4 antibody-induced Guillain-Barre syndrome in a melanoma patient
-
Wilgenhof S, Neyns B. Anti-CTLA-4 antibody-induced Guillain-Barre syndrome in a melanoma patient. Ann Oncol 2011; 22: 991-993.
-
(2011)
Ann Oncol
, vol.22
, pp. 991-993
-
-
Wilgenhof, S.1
Neyns, B.2
-
17
-
-
84964389238
-
Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy
-
Zimmer L, Goldinger SM, Hofmann L, et al. Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy. Eur J Cancer 2016; 60: 210-225.
-
(2016)
Eur J Cancer
, vol.60
, pp. 210-225
-
-
Zimmer, L.1
Goldinger, S.M.2
Hofmann, L.3
-
18
-
-
84896934432
-
Atypical neurological complications of ipilimumab therapy in patients with metastatic melanoma
-
Liao B, Shroff S, Kamiya-Matsuoka C, Tummala S. Atypical neurological complications of ipilimumab therapy in patients with metastatic melanoma. Neuro Oncol 2014; 16: 589-593.
-
(2014)
Neuro Oncol
, vol.16
, pp. 589-593
-
-
Liao, B.1
Shroff, S.2
Kamiya-Matsuoka, C.3
Tummala, S.4
-
19
-
-
0030062438
-
Chronic inflammatory demyelinating polyneuropathy associated with carcinoma
-
Antoine JC, Mosnier JF, Lapras J, et al. Chronic inflammatory demyelinating polyneuropathy associated with carcinoma. J Neurol Neurosurg Psychiatry 1996; 60: 188-190.
-
(1996)
J Neurol Neurosurg Psychiatry
, vol.60
, pp. 188-190
-
-
Antoine, J.C.1
Mosnier, J.F.2
Lapras, J.3
-
20
-
-
84875531958
-
Severe meningo-radiculo-neuritis associated with ipilimumab
-
Bompaire F, Mateus C, Taillia H, et al. Severe meningo-radiculo-neuritis associated with ipilimumab. Invest New Drugs 2012; 30: 2407-2410.
-
(2012)
Invest New Drugs
, vol.30
, pp. 2407-2410
-
-
Bompaire, F.1
Mateus, C.2
Taillia, H.3
-
21
-
-
63649143542
-
Inflammatory enteric neuropathy with severe constipation after ipilimumab treatment for melanoma: A case report
-
Bhatia S, Huber BR, Upton MP, Thompson JA. Inflammatory enteric neuropathy with severe constipation after ipilimumab treatment for melanoma: A case report. J Immunother 2009; 32: 203-205.
-
(2009)
J Immunother
, vol.32
, pp. 203-205
-
-
Bhatia, S.1
Huber, B.R.2
Upton, M.P.3
Thompson, J.A.4
-
22
-
-
84981271733
-
Association of autoimmune encephalitis with combined immune checkpoint inhibitor treatment for metastatic cancer
-
Williams TJ, Benavides DR, Patrice KA, et al. Association of autoimmune encephalitis with combined immune checkpoint inhibitor treatment for metastatic cancer. JAMA Neurol 2016; 73: 928-933.
-
(2016)
JAMA Neurol
, vol.73
, pp. 928-933
-
-
Williams, T.J.1
Benavides, D.R.2
Patrice, K.A.3
-
23
-
-
0142009530
-
Paraneoplastic syndromes involving the nervous system
-
Darnell RB, Posner JB. Paraneoplastic syndromes involving the nervous system. N Engl J Med 2003; 349: 1543-1554.
-
(2003)
N Engl J Med
, vol.349
, pp. 1543-1554
-
-
Darnell, R.B.1
Posner, J.B.2
-
24
-
-
84940107600
-
Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice
-
Planaguma J, Leypoldt F, Mannara F, et al. Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice. Brain 2015; 138: 94-109.
-
(2015)
Brain
, vol.138
, pp. 94-109
-
-
Planaguma, J.1
Leypoldt, F.2
Mannara, F.3
-
25
-
-
77951658372
-
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis
-
Hughes EG, Peng X, Gleichman AJ, et al. Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. J Neurosci 2010; 30: 5866-5875.
-
(2010)
J Neurosci
, vol.30
, pp. 5866-5875
-
-
Hughes, E.G.1
Peng, X.2
Gleichman, A.J.3
-
26
-
-
85027946522
-
Exome sequencing identifies GRIN2A as frequently mutated in melanoma
-
Wei X, Walia V, Lin JC, et al. Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nat Genet 2011; 43: 442-446.
-
(2011)
Nat Genet
, vol.43
, pp. 442-446
-
-
Wei, X.1
Walia, V.2
Lin, J.C.3
-
27
-
-
84937520489
-
Myasthenia gravis associated with ipilimumab and nivolumab in the treatment of small cell lung cancer
-
Loochtan AI, Nickolich MS, Hobson-Webb LD. Myasthenia gravis associated with ipilimumab and nivolumab in the treatment of small cell lung cancer. Muscle Nerve 2015; 52: 307-308.
-
(2015)
Muscle Nerve
, vol.52
, pp. 307-308
-
-
Loochtan, A.I.1
Nickolich, M.S.2
Hobson-Webb, L.D.3
-
28
-
-
84872339660
-
The price of tumor control: An analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network
-
Voskens CJ, Goldinger SM, Loquai C, et al. The price of tumor control: An analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network. PLoS One 2013; 8: E53745.
-
(2013)
PLoS One
, vol.8
, pp. e53745
-
-
Voskens, C.J.1
Goldinger, S.M.2
Loquai, C.3
-
29
-
-
84928142532
-
A genome-wide association study of myasthenia gravis
-
Renton AE, Pliner HA, Provenzano C, et al. A genome-wide association study of myasthenia gravis. JAMA Neurol 2015; 72: 396-404.
-
(2015)
JAMA Neurol
, vol.72
, pp. 396-404
-
-
Renton, A.E.1
Pliner, H.A.2
Provenzano, C.3
-
30
-
-
84857517981
-
Posterior reversible encephalopathy syndrome during ipilimumab therapy for malignant melanoma
-
Maur M, TomaselloC, Frassoldati A, et al. Posterior reversible encephalopathy syndrome during ipilimumab therapy for malignant melanoma. J Clin Oncol 2012; 30: E76-e78.
-
(2012)
J Clin Oncol
, vol.30
, pp. e76-e78
-
-
Maur, M.1
Tomasello, C.2
Frassoldati, A.3
-
31
-
-
84864052441
-
Management of immune-related adverse events and kinetics of response with ipilimumab
-
Weber JS, Kahler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol 2012; 30: 2691-2697.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2691-2697
-
-
Weber, J.S.1
Kahler, K.C.2
Hauschild, A.3
-
32
-
-
84949988089
-
Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies
-
Naidoo J, Page DB, Li BT, et al. Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies. Ann Oncol 2015; 26: 2375-2391.
-
(2015)
Ann Oncol
, vol.26
, pp. 2375-2391
-
-
Naidoo, J.1
Page, D.B.2
Li, B.T.3
-
34
-
-
0021079551
-
Vitiligo in patients with metastatic melanoma: A good prognostic sign
-
Nordlund JJ, Kirkwood JM, Forget BM, et al. Vitiligo in patients with metastatic melanoma: A good prognostic sign. J Am Acad Dermatol 1983; 9: 689-696.
-
(1983)
J Am Acad Dermatol
, vol.9
, pp. 689-696
-
-
Nordlund, J.J.1
Kirkwood, J.M.2
Forget, B.M.3
-
35
-
-
32644454916
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
Gogas H, Ioannovich J, Dafni U, et al. Prognostic significance of autoimmunity during treatment of melanoma with interferon. N Engl J Med 2006; 354: 709-718.
-
(2006)
N Engl J Med
, vol.354
, pp. 709-718
-
-
Gogas, H.1
Ioannovich, J.2
Dafni, U.3
-
36
-
-
36748999428
-
Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade
-
Downey SG, Klapper JA, Smith FO, et al. Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade. Clin Cancer Res 2007; 13: 6681-6688.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6681-6688
-
-
Downey, S.G.1
Klapper, J.A.2
Smith, F.O.3
-
37
-
-
20044395957
-
Autoimmunity in a phase I trial of a fully human anticytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma
-
Sanderson K, Scotland R, Lee P, et al. Autoimmunity in a phase I trial of a fully human anticytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma. J Clin Oncol 2005; 23: 741-750.
-
(2005)
J Clin Oncol
, vol.23
, pp. 741-750
-
-
Sanderson, K.1
Scotland, R.2
Lee, P.3
-
38
-
-
84855387108
-
Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity
-
Liu SM, Sutherland AP, Zhang Z, et al. Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity. J Immunol 2012; 188: 155-162.
-
(2012)
J Immunol
, vol.188
, pp. 155-162
-
-
Liu, S.M.1
Sutherland, A.P.2
Zhang, Z.3
-
39
-
-
84856769074
-
Evaluation of serum IL-17 levels during ipilimumab therapy: Correlation with colitis
-
Callahan MK, Yang A, Tandon S. Evaluation of serum IL-17 levels during ipilimumab therapy: Correlation with colitis. J Clin Oncol 2011; 29s: 2505.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2505
-
-
Callahan, M.K.1
Yang, A.2
Tandon, S.3
-
40
-
-
33244458474
-
Skin reactions in a subset of patients with stage IV melanoma treated with anticytotoxic T-lymphocyte antigen 4 monoclonal antibody as a single agent
-
Jaber SH, Cowen EW, Haworth LR, et al. Skin reactions in a subset of patients with stage IV melanoma treated with anticytotoxic T-lymphocyte antigen 4 monoclonal antibody as a single agent. Arch Dermatol 2006; 142: 166-172.
-
(2006)
Arch Dermatol
, vol.142
, pp. 166-172
-
-
Jaber, S.H.1
Cowen, E.W.2
Haworth, L.R.3
|