Design, synthesis, and preliminary evaluation of the biological activity of dithiocarbamate-3-epi-jaspine B hybrids

Medicinal Chemistry Research

Volumn 25, Issue 12, 2016, Pages 3011-3020

  Zhang, En ^a,b   Jiao, Wei Wei ^a,b   Wang, Shang ^a,b   Xu, Jin Mei ^a,b   Shi, Xiao Jing ^a,b   Wang, Yan Chao ^a,b   Wang, Ya Na ^a,b   Liu, Hong Min ^a,b  

^a ZHENGZHOU UNIVERSITY   (China)

^b Department of Pharmaceutics   (China)

Author keywords

Antitumor activity; D xylose; Dithiocarbamates; Jaspine B

Indexed keywords

ANTINEOPLASTIC AGENT; DECYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; DITHIOCARBAMIC ACID DERIVATIVE; DODECYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; FLUOROURACIL; HEPTYL [5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; HEXADECYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; JASPINE B; NONYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; OCTADECYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBMO DITHIOATE; OCTYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; TETRADECYL [4 HYDROXY 5 (HYDROXYMETHYL)TETRAHYDROFURAN 3 YL]CARBAMO DITHIOATE; UNCLASSIFIED DRUG; XYLOSE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; B16 F10 CELL LINE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MELANOMA CELL LINE; MGC 803 CELL LINE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84988566053     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-016-1721-9     Document Type: Article

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