-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
[1] Ferlay, J., Shin, H.-R., Bray, F., Forman, D., Mathers, C., Parkin, D.M., Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127 (2010), 2893–2917, 10.1002/ijc.25516.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.-R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
84872853140
-
Global estimates of cancer prevalence for 27 sites in the adult population in 2008
-
[2] Bray, F., Ren, J.-S., Masuyer, E., Ferlay, J., Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int. J. Cancer 132 (2013), 1133–1145, 10.1002/ijc.27711.
-
(2013)
Int. J. Cancer
, vol.132
, pp. 1133-1145
-
-
Bray, F.1
Ren, J.-S.2
Masuyer, E.3
Ferlay, J.4
-
3
-
-
84918815964
-
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
-
[3] Ferlay, J., Soerjomataram, I. I, Dikshit, R., Eser, S., Mathers, C., Rebelo, M., Parkin, D.M., Forman D, D., Bray, F., Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer 136 (2015), E359–E386, 10.1002/ijc.29210.
-
(2015)
Int. J. Cancer
, vol.136
, pp. E359-E386
-
-
Ferlay, J.1
Soerjomataram, I.2
Dikshit, R.3
Eser, S.4
Mathers, C.5
Rebelo, M.6
Parkin, D.M.7
Forman D, D.8
Bray, F.9
-
4
-
-
84988508386
-
-
World Cancer Research Fund International, Worldwide data, (accessed 08.02.15).
-
[4] World Cancer Research Fund International, Worldwide data, http://www.wcrf.org/int/cancer-facts-figures/worldwide-data (accessed 08.02.15).
-
-
-
-
5
-
-
84865682929
-
New anticancer agents: recent developments in tumor therapy
-
[5] Ali, R., Mirza, Z., Ashraf, G.M.D., Kamal, M.A., Ansari, S.A., Damanhouri, G.A., Abuzenadah, A.M., Chaudhary, A.G.A., Sheikh, I.A., New anticancer agents: recent developments in tumor therapy. Anticancer Res. 32 (2012), 2999–3005.
-
(2012)
Anticancer Res.
, vol.32
, pp. 2999-3005
-
-
Ali, R.1
Mirza, Z.2
Ashraf, G.M.D.3
Kamal, M.A.4
Ansari, S.A.5
Damanhouri, G.A.6
Abuzenadah, A.M.7
Chaudhary, A.G.A.8
Sheikh, I.A.9
-
6
-
-
84908375133
-
Nature as a remarkable chemist: a personal story of the discovery and development of Taxol
-
[6] Wani, M.C., Horwitz, S.B., Nature as a remarkable chemist: a personal story of the discovery and development of Taxol. Anticancer Drugs 25 (2014), 482–487, 10.1097/CAD.0000000000000063.
-
(2014)
Anticancer Drugs
, vol.25
, pp. 482-487
-
-
Wani, M.C.1
Horwitz, S.B.2
-
7
-
-
0029838904
-
The clinical use of mutagenic anticancer drugs
-
[7] Ferguson, L.R., Pearson, A.E., The clinical use of mutagenic anticancer drugs. Mutat. Res. 355 (1996), 1–12, 10.1016/0027-5107(96)00019-X.
-
(1996)
Mutat. Res.
, vol.355
, pp. 1-12
-
-
Ferguson, L.R.1
Pearson, A.E.2
-
8
-
-
79955597636
-
Drug therapy of cancer
-
[8] Peterson, C., Drug therapy of cancer. Eur. J. Clin. Pharmacol. 67 (2011), 437–447, 10.1007/s00228-011-1011-x.
-
(2011)
Eur. J. Clin. Pharmacol.
, vol.67
, pp. 437-447
-
-
Peterson, C.1
-
9
-
-
84895836004
-
Targeting tumour-supportive cellular machineries in anticancer drug development
-
[9] Dobbelstein, M., Moll, U., Targeting tumour-supportive cellular machineries in anticancer drug development. Nat. Rev. Drug Discov. 13 (2014), 179–196, 10.1038/nrd4201.
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 179-196
-
-
Dobbelstein, M.1
Moll, U.2
-
10
-
-
84959144672
-
Cancer stem cells and chemoresistance: the smartest survives the raid
-
[10] Zhao, J., Cancer stem cells and chemoresistance: the smartest survives the raid. Pharmacol. Ther. 160 (2016), 145–158, 10.1016/j.pharmthera.2016.02.008.
-
(2016)
Pharmacol. Ther.
, vol.160
, pp. 145-158
-
-
Zhao, J.1
-
11
-
-
84884535896
-
Cancer drug resistance: an evolving paradigm
-
[11] Holohan, C., Van Schaeybroeck, S., Longley, D.B., Johnston, P.G., Cancer drug resistance: an evolving paradigm. Nat. Rev. Cancer 13 (2013), 714–726, 10.1038/nrc3599.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 714-726
-
-
Holohan, C.1
Van Schaeybroeck, S.2
Longley, D.B.3
Johnston, P.G.4
-
12
-
-
84859438323
-
The valley of death in anticancer drug development: a reassessment
-
[12] Adams, D.J., The valley of death in anticancer drug development: a reassessment. Trends Pharmacol. Sci. 33 (2012), 173–180, 10.1016/j.tips.2012.02.001.
-
(2012)
Trends Pharmacol. Sci.
, vol.33
, pp. 173-180
-
-
Adams, D.J.1
-
13
-
-
71749100398
-
Cationic amphiphilic peptides with cancer-selective toxicity
-
[13] Schweizer, F., Cationic amphiphilic peptides with cancer-selective toxicity. Eur. J. Pharmacol. 625 (2009), 190–194, 10.1016/j.ejphar.2009.08.043.
-
(2009)
Eur. J. Pharmacol.
, vol.625
, pp. 190-194
-
-
Schweizer, F.1
-
14
-
-
84885416827
-
From antimicrobial to anticancer peptides. A review
-
[14] Gaspar, D., Salomé Veiga, A., Castanho, M.A.R.B., From antimicrobial to anticancer peptides. A review. Front. Microbiol., 4(294), 2013, 10.3389/fmicb.2013.00294.
-
(2013)
Front. Microbiol.
, vol.4
, Issue.294
-
-
Gaspar, D.1
Salomé Veiga, A.2
Castanho, M.A.R.B.3
-
15
-
-
82255189885
-
Oncolytic activities of host defense peptides
-
[15] Al-Benna, S., Shai, Y., Jacobsen, F., Steinstraesser, L., Oncolytic activities of host defense peptides. Int. J. Mol. Sci. 12 (2011), 8027–8051, 10.3390/ijms12118027.
-
(2011)
Int. J. Mol. Sci.
, vol.12
, pp. 8027-8051
-
-
Al-Benna, S.1
Shai, Y.2
Jacobsen, F.3
Steinstraesser, L.4
-
16
-
-
84880996730
-
Melittin: a lytic peptide with anticancer properties
-
[16] Gajski, G., Garaj-Vrhovac, V., Melittin: a lytic peptide with anticancer properties. Environ. Toxicol. Pharmacol. 36 (2013), 697–705, 10.1016/j.etap.2013.06.009.
-
(2013)
Environ. Toxicol. Pharmacol.
, vol.36
, pp. 697-705
-
-
Gajski, G.1
Garaj-Vrhovac, V.2
-
17
-
-
40649123558
-
The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8
-
[17] Wrasidlo, W., Mielgo, A., a Torres, V., Barbero, S., Stoletov, K., Suyama, T.L., Klemke, R.L., Gerwick, W.H., a Carson, D., Stupack, D.G., The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 2313–2318, 10.1073/pnas.0712198105.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 2313-2318
-
-
Wrasidlo, W.1
Mielgo, A.2
a Torres, V.3
Barbero, S.4
Stoletov, K.5
Suyama, T.L.6
Klemke, R.L.7
Gerwick, W.H.8
a Carson, D.9
Stupack, D.G.10
-
18
-
-
79960384535
-
Antitumor cell activity in vitro by myristoylated-peptide
-
[18] Ourth, D.D., Antitumor cell activity in vitro by myristoylated-peptide. Biomed. Pharmacother. 65 (2011), 271–274, 10.1016/j.biopha.2011.02.015.
-
(2011)
Biomed. Pharmacother.
, vol.65
, pp. 271-274
-
-
Ourth, D.D.1
-
19
-
-
84961721905
-
Short antimicrobial peptides and peptide scaffolds as promising antibacterial agents
-
[19] Domalaon, R., Zhanel, G.G., Schweizer, F., Short antimicrobial peptides and peptide scaffolds as promising antibacterial agents. Curr. Top. Med. Chem. 16 (2016), 1217–1230, 10.2174/1568026615666150915112459.
-
(2016)
Curr. Top. Med. Chem.
, vol.16
, pp. 1217-1230
-
-
Domalaon, R.1
Zhanel, G.G.2
Schweizer, F.3
-
20
-
-
33750446295
-
Ultrashort antibacterial and antifungal lipopeptides
-
[20] Makovitzki, A., Avrahami, D., Shai, Y., Ultrashort antibacterial and antifungal lipopeptides. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 15997–16002, 10.1073/pnas.0606129103.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 15997-16002
-
-
Makovitzki, A.1
Avrahami, D.2
Shai, Y.3
-
21
-
-
53249151770
-
Antimicrobial lipopolypeptides composed of palmitoyl di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action
-
[21] Makovitzki, A., Baram, J., Shai, Y., Antimicrobial lipopolypeptides composed of palmitoyl di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action. Biochemistry 47 (2008), 10630–10636, 10.1021/bi8011675.
-
(2008)
Biochemistry
, vol.47
, pp. 10630-10636
-
-
Makovitzki, A.1
Baram, J.2
Shai, Y.3
-
22
-
-
66149142186
-
Antibacterial activity of ultrashort cationic lipo-beta-peptides
-
[22] Serrano, G.N., Zhanel, G.G., Schweizer, F., Antibacterial activity of ultrashort cationic lipo-beta-peptides. Antimicrob. Agents Chemother. 53 (2009), 2215–2217, 10.1128/AAC.01100-08.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2215-2217
-
-
Serrano, G.N.1
Zhanel, G.G.2
Schweizer, F.3
-
23
-
-
84861875478
-
Investigating the antimicrobial peptide window of activity using cationic lipopeptides with hydrocarbon and fluorinated tails
-
[23] Findlay, B., Zhanel, G.G., Schweizer, F., Investigating the antimicrobial peptide window of activity using cationic lipopeptides with hydrocarbon and fluorinated tails. Int. J. Antimicrob. Agents 40 (2012), 36–42, 10.1016/j.ijantimicag.2012.03.013.
-
(2012)
Int. J. Antimicrob. Agents
, vol.40
, pp. 36-42
-
-
Findlay, B.1
Zhanel, G.G.2
Schweizer, F.3
-
24
-
-
84864197064
-
Guanidylation and tail effects in cationic antimicrobial lipopeptoids
-
[24] Findlay, B., Szelemej, P., Zhanel, G.G., Schweizer, F., Guanidylation and tail effects in cationic antimicrobial lipopeptoids. PLoS One, 7, 2012, e41141, 10.1371/journal.pone.0041141.
-
(2012)
PLoS One
, vol.7
, pp. e41141
-
-
Findlay, B.1
Szelemej, P.2
Zhanel, G.G.3
Schweizer, F.4
-
25
-
-
84933517638
-
Structure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity
-
[25] Domalaon, R., Yang, X., O'Neil, J., Zhanel, G.G., Mookherjee, N., Schweizer, F., Structure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity. Amino Acids 46 (2014), 2517–2530, 10.1007/s00726-014-1806-z.
-
(2014)
Amino Acids
, vol.46
, pp. 2517-2530
-
-
Domalaon, R.1
Yang, X.2
O'Neil, J.3
Zhanel, G.G.4
Mookherjee, N.5
Schweizer, F.6
-
26
-
-
84873497595
-
Ultrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophages
-
[26] Findlay, B., Mookherjee, N., Schweizer, F., Ultrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophages. PLoS One, 8, 2013, e54280, 10.1371/journal.pone.0054280.
-
(2013)
PLoS One
, vol.8
, pp. e54280
-
-
Findlay, B.1
Mookherjee, N.2
Schweizer, F.3
-
27
-
-
0041666539
-
Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties
-
[27] Caserta, T.M., Smith, A.N., Gultice, A.D., Reedy, M.A., Brown, T.L., Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties. Apoptosis 8 (2003), 345–352.
-
(2003)
Apoptosis
, vol.8
, pp. 345-352
-
-
Caserta, T.M.1
Smith, A.N.2
Gultice, A.D.3
Reedy, M.A.4
Brown, T.L.5
-
28
-
-
10144229398
-
Peptide helicity and membrane surface charge modulate the balance of electrostatic and hydrophobic interactions with lipid bilayers and biological membranes
-
[28] Datrie, M., Schumann, M., Wieprecht, T., Winkler, A., Beyermann, M., Krause, E., Matsuzaki, K., Murase, O., Bienert, M., Peptide helicity and membrane surface charge modulate the balance of electrostatic and hydrophobic interactions with lipid bilayers and biological membranes. Biochemistry 35 (1996), 12612–12622, 10.1021/bi960835f.
-
(1996)
Biochemistry
, vol.35
, pp. 12612-12622
-
-
Datrie, M.1
Schumann, M.2
Wieprecht, T.3
Winkler, A.4
Beyermann, M.5
Krause, E.6
Matsuzaki, K.7
Murase, O.8
Bienert, M.9
-
29
-
-
39749182234
-
Apoptosis: controlled demolition at the cellular level
-
[29] Taylor, R.C., Cullen, S.P., Martin, S.J., Apoptosis: controlled demolition at the cellular level. Nat. Rev. Mol. Cell Biol. 9 (2008), 231–241, 10.1038/nrm2312.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 231-241
-
-
Taylor, R.C.1
Cullen, S.P.2
Martin, S.J.3
-
30
-
-
2942616456
-
Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. Intermediacy of H(2)O(2)- and p53-dependent pathways
-
[30] Wang, S., Konorev, E.A., Kotamraju, S., Joseph, J., Kalivendi, S., Kalyanaraman, B., Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. Intermediacy of H(2)O(2)- and p53-dependent pathways. J. Biol. Chem. 279 (2004), 25535–25543, 10.1074/jbc.M400944200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25535-25543
-
-
Wang, S.1
Konorev, E.A.2
Kotamraju, S.3
Joseph, J.4
Kalivendi, S.5
Kalyanaraman, B.6
-
31
-
-
84874318706
-
Structure-activity relationships of glucosamine-derived glycerolipids: the role of the anomeric linkage, the cationic charge and the glycero moiety on the antitumor activity
-
[31] Xu, Y., Ogunsina, M., Samadder, P., Arthur, G., Schweizer, F., Structure-activity relationships of glucosamine-derived glycerolipids: the role of the anomeric linkage, the cationic charge and the glycero moiety on the antitumor activity. ChemMedChem 8 (2013), 511–520, 10.1002/cmdc.201200489.
-
(2013)
ChemMedChem
, vol.8
, pp. 511-520
-
-
Xu, Y.1
Ogunsina, M.2
Samadder, P.3
Arthur, G.4
Schweizer, F.5
-
32
-
-
64149103140
-
Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function
-
[32] Fowler, S.A., Blackwell, H.E., Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function. Org. Biomol. Chem. 7 (2009), 1508–1524, 10.1039/b817980h.
-
(2009)
Org. Biomol. Chem.
, vol.7
, pp. 1508-1524
-
-
Fowler, S.A.1
Blackwell, H.E.2
-
33
-
-
84896500814
-
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity
-
[33] Huang, W., Seo, J., Willingham, S.B., Czyzewski, A.M., Gonzalgo, M.L., Weissman, I.L., Barron, A.E., Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity. PLoS One, 9, 2014, e90397, 10.1371/journal.pone.0090397.
-
(2014)
PLoS One
, vol.9
, pp. e90397
-
-
Huang, W.1
Seo, J.2
Willingham, S.B.3
Czyzewski, A.M.4
Gonzalgo, M.L.5
Weissman, I.L.6
Barron, A.E.7
-
34
-
-
84878259928
-
Polyproline-II helix in proteins: structure and function
-
[34] Adzhubei, A.A., Sternberg, M.J.E., Makarov, A.A., Polyproline-II helix in proteins: structure and function. J. Mol. Biol. 425 (2013), 2100–2132, 10.1016/j.jmb.2013.03.018.
-
(2013)
J. Mol. Biol.
, vol.425
, pp. 2100-2132
-
-
Adzhubei, A.A.1
Sternberg, M.J.E.2
Makarov, A.A.3
-
35
-
-
23944492106
-
Cell penetrating agents based on a polyproline helix scaffold
-
[35] Fillon, Y.A., Anderson, J.P., Chmielewski, J., Cell penetrating agents based on a polyproline helix scaffold. J. Am. Chem. Soc. 127 (2005), 11798–11803, 10.1021/ja052377g.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 11798-11803
-
-
Fillon, Y.A.1
Anderson, J.P.2
Chmielewski, J.3
-
36
-
-
34247382518
-
Probing length effects and mechanism of cell penetrating agents mounted on a polyproline helix scaffold
-
[36] Geisler, I., Chmielewski, J., Probing length effects and mechanism of cell penetrating agents mounted on a polyproline helix scaffold. Bioorg. Med. Chem. Lett. 17 (2007), 2765–2768, 10.1016/j.bmcl.2007.02.077.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 2765-2768
-
-
Geisler, I.1
Chmielewski, J.2
-
37
-
-
84655166544
-
Mitochondrial targeting of a cationic amphiphilic polyproline helix
-
[37] Kalafut, D., Anderson, T.N., Chmielewski, J., Mitochondrial targeting of a cationic amphiphilic polyproline helix. Bioorg. Med. Chem. Lett. 22 (2012), 561–563, 10.1016/j.bmcl.2011.10.077.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 561-563
-
-
Kalafut, D.1
Anderson, T.N.2
Chmielewski, J.3
-
38
-
-
33749319699
-
Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen
-
[38] Yip, K.W., Mao, X., Au, P.Y., Hedley, D.W., Chow, S., Dalili, S., Mocanu, J.D., Bastianutto, C., Schimmer, A., Liu, F.F., Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen. Clin. Cancer Res. 12 (2006), 5557–5569, 10.1158/1078-0432.CCR-06-0536.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5557-5569
-
-
Yip, K.W.1
Mao, X.2
Au, P.Y.3
Hedley, D.W.4
Chow, S.5
Dalili, S.6
Mocanu, J.D.7
Bastianutto, C.8
Schimmer, A.9
Liu, F.F.10
-
39
-
-
34247854895
-
Cationic surfactants induce apoptosis in normal and cancer cells
-
[39] Enomoto, R., Suzuki, C., Ohno, M., Ohasi, T., Futagami, R., Ishikawa, K., Komae, M., Nishino, T., Konishi, Y., Lee, E., Cationic surfactants induce apoptosis in normal and cancer cells. Ann. N. Y. Acad. Sci. 1095 (2007), 1–6, 10.1196/annals.1397.001.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1095
, pp. 1-6
-
-
Enomoto, R.1
Suzuki, C.2
Ohno, M.3
Ohasi, T.4
Futagami, R.5
Ishikawa, K.6
Komae, M.7
Nishino, T.8
Konishi, Y.9
Lee, E.10
-
40
-
-
84900792294
-
Die another way-non-apoptotic mechanisms of cell death
-
[40] Tait, S.W.G., Ichim, G., Green, D.R., Die another way-non-apoptotic mechanisms of cell death. J. Cell Sci. 127 (2014), 2135–2144, 10.1242/jcs.093575.
-
(2014)
J. Cell Sci.
, vol.127
, pp. 2135-2144
-
-
Tait, S.W.G.1
Ichim, G.2
Green, D.R.3
-
41
-
-
14644412456
-
Do inducers of apoptosis trigger caspase-independent cell death?
-
[41] Chipuk, J.E., Green, D.R., Do inducers of apoptosis trigger caspase-independent cell death?. Nat. Rev. Mol. Cell Biol. 6 (2005), 268–275, 10.1038/nrm1573.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 268-275
-
-
Chipuk, J.E.1
Green, D.R.2
-
42
-
-
79960934532
-
Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action
-
[42] Mangoni, M.L., Shai, Y., Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action. Cell. Mol. Life Sci. 68 (2011), 2267–2280, 10.1007/s00018-011-0718-2.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 2267-2280
-
-
Mangoni, M.L.1
Shai, Y.2
|