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Volumn 6, Issue , 2016, Pages

Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms

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EID: 84988472348     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep31414     Document Type: Article
Times cited : (17)

References (51)
  • 3
    • 33646449061 scopus 로고    scopus 로고
    • Inflammation and cellular immune responses in abdominal aortic aneurysms
    • Shimizu, K., Mitchell, R. N. & Libby, P. Inflammation and cellular immune responses in abdominal aortic aneurysms. Arteriosclerosis, thrombosis, and vascular biology 26, 987-994, doi: 10. 1161/01. ATV. 0000214999. 12921. 4f (2006).
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , pp. 987-994
    • Shimizu, K.1    Mitchell, R.N.2    Libby, P.3
  • 4
    • 84921653721 scopus 로고    scopus 로고
    • Mechanisms of aortic aneurysm formation: Translating preclinical studies into clinical therapies
    • Davis, F. M., Rateri, D. L. & Daugherty, A. Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies. Heart 100, 1498-1505, doi: 10. 1136/heartjnl-2014-305648 (2014).
    • (2014) Heart , vol.100 , pp. 1498-1505
    • Davis, F.M.1    Rateri, D.L.2    Daugherty, A.3
  • 5
    • 0025025349 scopus 로고
    • Atherosclerosis and aneurysm disease
    • Tilson, M. D. Atherosclerosis and aneurysm disease. Journal of vascular surgery 12, 371-372 (1990).
    • (1990) Journal of Vascular Surgery , vol.12 , pp. 371-372
    • Tilson, M.D.1
  • 6
    • 77952886312 scopus 로고    scopus 로고
    • Atherosclerosis in abdominal aortic aneurysms: A causal event or a process running in parallel? the Tromso study
    • Johnsen, S. H., Forsdahl, S. H., Singh, K. & Jacobsen, B. K. Atherosclerosis in abdominal aortic aneurysms: a causal event or a process running in parallel? The Tromso study. Arteriosclerosis, thrombosis, and vascular biology 30, 1263-1268, doi: 10. 1161/ ATVBAHA. 110. 203588 (2010).
    • (2010) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.30 , pp. 1263-1268
    • Johnsen, S.H.1    Forsdahl, S.H.2    Singh, K.3    Jacobsen, B.K.4
  • 7
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil, G. S. Inflammation and metabolic disorders. Nature 444, 860-867, doi: 10. 1038/nature05485 (2006).
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 8
    • 84908127334 scopus 로고    scopus 로고
    • Adiponectin attenuates abdominal aortic aneurysm formation in hyperlipidemic mice
    • Yoshida, S., Fuster, J. J. & Walsh, K. Adiponectin attenuates abdominal aortic aneurysm formation in hyperlipidemic mice. Atherosclerosis 235, 339-346, doi: 10. 1016/j. atherosclerosis. 2014. 05. 923 (2014).
    • (2014) Atherosclerosis , vol.235 , pp. 339-346
    • Yoshida, S.1    Fuster, J.J.2    Walsh, K.3
  • 9
    • 84872959139 scopus 로고    scopus 로고
    • Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice
    • Tao, M. et al. Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice. Arteriosclerosis, thrombosis, and vascular biology 33, 311-320, doi: 10. 1161/ATVBAHA. 112. 300543 (2013).
    • (2013) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.33 , pp. 311-320
    • Tao, M.1
  • 10
    • 36048977283 scopus 로고    scopus 로고
    • Obesity, adipokines, and abdominal aortic aneurysm: Health in Men study
    • Golledge, J., Clancy, P., Jamrozik, K. & Norman, P. E. Obesity, adipokines, and abdominal aortic aneurysm: Health in Men study. Circulation 116, 2275-2279, doi: 10. 1161/CIRCULATIONAHA. 107. 717926 (2007).
    • (2007) Circulation , vol.116 , pp. 2275-2279
    • Golledge, J.1    Clancy, P.2    Jamrozik, K.3    Norman, P.E.4
  • 11
    • 84899657349 scopus 로고    scopus 로고
    • Adiponectin Expression Protects against Angiotensin IIMediated Inflammation and Accelerated Atherosclerosis
    • van Stijn, C. M., Kim, J., Barish, G. D., Tietge, U. J. & Tangirala, R. K. Adiponectin Expression Protects against Angiotensin IIMediated Inflammation and Accelerated Atherosclerosis. PloS one 9, e86404, doi: 10. 1371/journal. pone. 0086404 (2014).
    • (2014) PloS One , vol.9 , pp. e86404
    • Van Stijn, C.M.1    Kim, J.2    Barish, G.D.3    Tietge, U.J.4    Tangirala, R.K.5
  • 12
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • Berg, A. H. & Scherer, P. E. Adipose tissue, inflammation, and cardiovascular disease. Circulation research 96, 939-949, doi: 10. 1161/01. RES. 0000163635. 62927. 34 (2005).
    • (2005) Circulation Research , vol.96 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 13
    • 77954322164 scopus 로고    scopus 로고
    • Low plasma adiponectin concentration is associated with myocardial infarction in young individuals
    • Persson, J. et al. Low plasma adiponectin concentration is associated with myocardial infarction in young individuals. Journal of internal medicine 268, 194-205, doi: 10. 1111/j. 1365-2796. 2010. 02247. x (2010).
    • (2010) Journal of Internal Medicine , vol.268 , pp. 194-205
    • Persson, J.1
  • 14
    • 78651260799 scopus 로고    scopus 로고
    • Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
    • Holland, W. L. et al. Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nature medicine 17, 55-63, doi: 10. 1038/nm. 2277 (2011).
    • (2011) Nature Medicine , vol.17 , pp. 55-63
    • Holland, W.L.1
  • 15
    • 33847733103 scopus 로고    scopus 로고
    • Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
    • Yamauchi, T. et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nature medicine 13, 332-339, doi: 10. 1038/nm1557 (2007).
    • (2007) Nature Medicine , vol.13 , pp. 332-339
    • Yamauchi, T.1
  • 17
    • 11144355637 scopus 로고    scopus 로고
    • Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity
    • Pajvani, U. B. et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. The Journal of biological chemistry 279, 12152-12162, doi: 10. 1074/jbc. M311113200 (2004).
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 12152-12162
    • Pajvani, U.B.1
  • 18
    • 0032787345 scopus 로고    scopus 로고
    • Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor ?/? Mice
    • Daugherty, A. & Cassis, L. Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor ?/? mice. Annals of the New York Academy of Sciences 892, 108-118 (1999).
    • (1999) Annals of the New York Academy of Sciences , vol.892 , pp. 108-118
    • Daugherty, A.1    Cassis, L.2
  • 19
    • 0031446107 scopus 로고    scopus 로고
    • Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms
    • Thompson, R. W., Liao, S. & Curci, J. A. Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms. Coronary artery disease 8, 623-631 (1997).
    • (1997) Coronary Artery Disease , vol.8 , pp. 623-631
    • Thompson, R.W.1    Liao, S.2    Curci, J.A.3
  • 20
    • 4043127656 scopus 로고    scopus 로고
    • Adaptive cellular immunity in aortic aneurysms: Cause, consequence, or context?
    • Curci, J. A. & Thompson, R. W. Adaptive cellular immunity in aortic aneurysms: cause, consequence, or context? The Journal of clinical investigation 114, 168-171, doi: 10. 1172/JCI22309 (2004).
    • (2004) The Journal of Clinical Investigation , vol.114 , pp. 168-171
    • Curci, J.A.1    Thompson, R.W.2
  • 21
    • 0031044735 scopus 로고    scopus 로고
    • Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms
    • Lopez-Candales, A. et al. Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms. The American journal of pathology 150, 993-1007 (1997).
    • (1997) The American Journal of Pathology , vol.150 , pp. 993-1007
    • Lopez-Candales, A.1
  • 22
    • 33846444939 scopus 로고    scopus 로고
    • Bone marrow transplantation reveals that recipient AT1a receptors are required to initiate angiotensin II-induced atherosclerosis and aneurysms
    • Cassis, L. A., Rateri, D. L., Lu, H. & Daugherty, A. Bone marrow transplantation reveals that recipient AT1a receptors are required to initiate angiotensin II-induced atherosclerosis and aneurysms. Arteriosclerosis, thrombosis, and vascular biology 27, 380-386, doi: 10. 1161/01. ATV. 0000254680. 71485. 92 (2007).
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , pp. 380-386
    • Cassis, L.A.1    Rateri, D.L.2    Lu, H.3    Daugherty, A.4
  • 23
    • 79953766381 scopus 로고    scopus 로고
    • Mast cells: Important players in the orchestrated pathogenesis of abdominal aortic aneurysms
    • Swedenborg, J., Mayranpaa, M. I. & Kovanen, P. T. Mast cells: important players in the orchestrated pathogenesis of abdominal aortic aneurysms. Arteriosclerosis, thrombosis, and vascular biology 31, 734-740, doi: 10. 1161/ATVBAHA. 110. 213157 (2011).
    • (2011) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.31 , pp. 734-740
    • Swedenborg, J.1    Mayranpaa, M.I.2    Kovanen, P.T.3
  • 24
    • 21544475911 scopus 로고    scopus 로고
    • Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm
    • Kazi, M. et al. Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm. Arteriosclerosis, thrombosis, and vascular biology 25, 1341-1346, doi: 10. 1161/01. ATV. 0000166601. 49954. 21 (2005).
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , pp. 1341-1346
    • Kazi, M.1
  • 25
    • 70349763716 scopus 로고    scopus 로고
    • Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation
    • Sun, J. et al. Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation 120, 973-982, doi: 10. 1161/CIRCULATIONAHA. 109. 849679 (2009).
    • (2009) Circulation , vol.120 , pp. 973-982
    • Sun, J.1
  • 26
    • 0034090148 scopus 로고    scopus 로고
    • Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms
    • Pyo, R. et al. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. The Journal of clinical investigation 105, 1641-1649, doi: 10. 1172/JCI8931 (2000).
    • (2000) The Journal of Clinical Investigation , vol.105 , pp. 1641-1649
    • Pyo, R.1
  • 27
    • 0037027504 scopus 로고    scopus 로고
    • Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice
    • Maki, J. M. et al. Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice. Circulation 106, 2503-2509 (2002).
    • (2002) Circulation , vol.106 , pp. 2503-2509
    • Maki, J.M.1
  • 29
    • 17344366565 scopus 로고    scopus 로고
    • Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm
    • Juvonen, J. et al. Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm. Arteriosclerosis, thrombosis, and vascular biology 17, 2843-2847 (1997).
    • (1997) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.17 , pp. 2843-2847
    • Juvonen, J.1
  • 30
    • 70349144900 scopus 로고    scopus 로고
    • A systematic review of studies examining inflammation associated cytokines in human abdominal aortic aneurysm samples
    • Golledge, A. L., Walker, P., Norman, P. E. & Golledge, J. A systematic review of studies examining inflammation associated cytokines in human abdominal aortic aneurysm samples. Disease markers 26, 181-188, doi: 10. 3233/DMA-2009-0629 (2009).
    • (2009) Disease Markers , vol.26 , pp. 181-188
    • Golledge, A.L.1    Walker, P.2    Norman, P.E.3    Golledge, J.4
  • 31
    • 70349578367 scopus 로고    scopus 로고
    • Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation
    • Police, S. B., Thatcher, S. E., Charnigo, R., Daugherty, A. & Cassis, L. A. Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation. Arteriosclerosis, thrombosis, and vascular biology 29, 1458-1464, doi: 10. 1161/ATVBAHA. 109. 192658 (2009).
    • (2009) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.29 , pp. 1458-1464
    • Police, S.B.1    Thatcher, S.E.2    Charnigo, R.3    Daugherty, A.4    Cassis, L.A.5
  • 32
    • 80052845699 scopus 로고    scopus 로고
    • Prolonged infusion of angiotensin II in apoE(?/?) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm
    • Rateri, D. L. et al. Prolonged infusion of angiotensin II in apoE(?/?) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm. The American journal of pathology 179, 1542-1548, doi: 10. 1016/j. ajpath. 2011. 05. 049 (2011).
    • (2011) The American Journal of Pathology , vol.179 , pp. 1542-1548
    • Rateri, D.L.1
  • 33
    • 0034129997 scopus 로고    scopus 로고
    • Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice
    • Daugherty, A., Manning, M. W. & Cassis, L. A. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. The Journal of clinical investigation 105, 1605-1612, doi: 10. 1172/JCI7818 (2000).
    • (2000) The Journal of Clinical Investigation , vol.105 , pp. 1605-1612
    • Daugherty, A.1    Manning, M.W.2    Cassis, L.A.3
  • 34
    • 65449116497 scopus 로고    scopus 로고
    • Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan
    • Fujiwara, Y. et al. Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan. International journal of molecular medicine 22, 703-708 (2008).
    • (2008) International Journal of Molecular Medicine , vol.22 , pp. 703-708
    • Fujiwara, Y.1
  • 35
    • 59849112584 scopus 로고    scopus 로고
    • Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation
    • Kaschina, E. et al. Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation. Journal of hypertension 26, 2361-2373, doi: 10. 1097/HJH. 0b013e328313e547 (2008).
    • (2008) Journal of Hypertension , vol.26 , pp. 2361-2373
    • Kaschina, E.1
  • 36
    • 42249103284 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts
    • Jones, G. T. et al. Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts. Arteriosclerosis, thrombosis, and vascular biology 28, 764-770, doi: 10. 1161/ATVBAHA. 107. 155564 (2008).
    • (2008) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.28 , pp. 764-770
    • Jones, G.T.1
  • 37
    • 0029089366 scopus 로고
    • Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm
    • Freestone, T. et al. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arteriosclerosis, thrombosis, and vascular biology 15, 1145-1151 (1995).
    • (1995) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.15 , pp. 1145-1151
    • Freestone, T.1
  • 38
    • 28644445776 scopus 로고    scopus 로고
    • Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase
    • Yoshimura, K. et al. Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase. Nature medicine 11, 1330-1338, doi: 10. 1038/nm1335 (2005).
    • (2005) Nature Medicine , vol.11 , pp. 1330-1338
    • Yoshimura, K.1
  • 39
    • 74749083638 scopus 로고    scopus 로고
    • Lysyl oxidase resolves inflammation by reducing monocyte chemoattractant protein-1 in abdominal aortic aneurysm
    • Onoda, M. et al. Lysyl oxidase resolves inflammation by reducing monocyte chemoattractant protein-1 in abdominal aortic aneurysm. Atherosclerosis 208, 366-369, doi: 10. 1016/j. atherosclerosis. 2009. 07. 036 (2010).
    • (2010) Atherosclerosis , vol.208 , pp. 366-369
    • Onoda, M.1
  • 40
    • 0031014499 scopus 로고    scopus 로고
    • Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases
    • Knox, J. B., Sukhova, G. K., Whittemore, A. D. & Libby, P. Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases. Circulation 95, 205-212 (1997).
    • (1997) Circulation , vol.95 , pp. 205-212
    • Knox, J.B.1    Sukhova, G.K.2    Whittemore, A.D.3    Libby, P.4
  • 42
    • 33646054230 scopus 로고    scopus 로고
    • Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-kappaB-mediated survival signaling
    • Leskinen, M. J. et al. Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-kappaB-mediated survival signaling. Experimental cell research 312, 1289-1298, doi: 10. 1016/j. yexcr. 2005. 12. 033 (2006).
    • (2006) Experimental Cell Research , vol.312 , pp. 1289-1298
    • Leskinen, M.J.1
  • 43
    • 67651004324 scopus 로고    scopus 로고
    • Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms
    • discussion 395-386
    • Mayranpaa, M. I. et al. Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms. Journal of vascular surgery 50, 388-395; discussion 395-386, doi: 10. 1016/j. jvs. 2009. 03. 055 (2009).
    • (2009) Journal of Vascular Surgery , vol.50 , pp. 388-395
    • Mayranpaa, M.I.1
  • 45
    • 84868274388 scopus 로고    scopus 로고
    • Mast cell chymase and tryptase in abdominal aortic aneurysm formation
    • Wang, Y. & Shi, G. P. Mast cell chymase and tryptase in abdominal aortic aneurysm formation. Trends in cardiovascular medicine 22, 150-155, doi: 10. 1016/j. tcm. 2012. 07. 012 (2012).
    • (2012) Trends in Cardiovascular Medicine , vol.22 , pp. 150-155
    • Wang, Y.1    Shi, G.P.2
  • 46
    • 0036968857 scopus 로고    scopus 로고
    • T(H)2 predominant immune responses prevail in human abdominal aortic aneurysm
    • Schonbeck, U., Sukhova, G. K., Gerdes, N. & Libby, P. T(H)2 predominant immune responses prevail in human abdominal aortic aneurysm. The American journal of pathology 161, 499-506, doi: 10. 1016/S0002-9440(10)64206-X (2002).
    • (2002) The American Journal of Pathology , vol.161 , pp. 499-506
    • Schonbeck, U.1    Sukhova, G.K.2    Gerdes, N.3    Libby, P.4
  • 47
    • 0033048632 scopus 로고    scopus 로고
    • Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
    • Frostegard, J. et al. Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 145, 33-43 (1999).
    • (1999) Atherosclerosis , vol.145 , pp. 33-43
    • Frostegard, J.1
  • 48
    • 0842300338 scopus 로고    scopus 로고
    • Key roles of CD4+ T cells and IFN-gamma in the development of abdominal aortic aneurysms in a murine model
    • Xiong, W., Zhao, Y., Prall, A., Greiner, T. C. & Baxter, B. T. Key roles of CD4+ T cells and IFN-gamma in the development of abdominal aortic aneurysms in a murine model. Journal of immunology 172, 2607-2612 (2004).
    • (2004) Journal of Immunology , vol.172 , pp. 2607-2612
    • Xiong, W.1    Zhao, Y.2    Prall, A.3    Greiner, T.C.4    Baxter, B.T.5
  • 49
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • Murray, P. J. & Wynn, T. A. Protective and pathogenic functions of macrophage subsets. Nature reviews. Immunology 11, 723-737, doi: 10. 1038/nri3073 (2011).
    • (2011) Nature Reviews. Immunology , vol.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 50
    • 33845233426 scopus 로고    scopus 로고
    • The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension
    • Watanabe, S. et al. The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension. Clinical therapeutics 28, 1677-1685, doi: 10. 1016/j. clinthera. 2006. 10. 012 (2006).
    • (2006) Clinical Therapeutics , vol.28 , pp. 1677-1685
    • Watanabe, S.1
  • 51
    • 41949123156 scopus 로고    scopus 로고
    • PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis
    • Takata, Y. et al. PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Proc Natl Acad Sci USA 105, 4277-4282, doi: 10. 1073/pnas. 0708647105 (2008).
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4277-4282
    • Takata, Y.1


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