-
1
-
-
84918815964
-
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
-
Ferlay, J. et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136, E359-E386, doi: 10.1002/ijc.29210 (2015).
-
(2015)
Int J Cancer
, vol.136
, pp. E359-E386
-
-
Ferlay, J.1
-
2
-
-
84954400636
-
Cancer statistics, 2016
-
Siegel, R. L., Miller, K. D. & Jemal, A. Cancer statistics, 2016. CA Cancer J Clin 66, 7-30, doi: 10.3322/caac.21332 (2016).
-
(2016)
CA Cancer J Clin
, vol.66
, pp. 7-30
-
-
Siegel, R.L.1
Miller, K.D.2
Jemal, A.3
-
3
-
-
20244388126
-
Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
-
Mitsudomi, T. et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 23, 2513-2520, doi: 10.1200/JCO.2005.00.992 (2005).
-
(2005)
J Clin Oncol
, vol.23
, pp. 2513-2520
-
-
Mitsudomi, T.1
-
4
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok, T. S. et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 361, 947-957, doi: 10.1056/NEJMoa0810699 (2009).
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
-
5
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutationpositive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell, R. et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutationpositive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial. Lancet Oncol 13, 239-246, doi: 10.1016/S1470-2045(11)70393-X (2012).
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
-
6
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-smallcell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou, C. et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-smallcell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study. Lancet Oncol 12, 735-742, doi: 10.1016/S1470-2045(11)70184-X (2011).
-
(2011)
Lancet Oncol
, vol.12
, pp. 735-742
-
-
Zhou, C.1
-
7
-
-
84872020299
-
Cancer genome scanning in plasma: Detection of tumor-Associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
-
Chan, K. C. et al. Cancer genome scanning in plasma: detection of tumor-Associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing. Clin Chem 59, 211-224, doi: 10.1373/clinchem.2012.196014 (2013).
-
(2013)
Clin Chem
, vol.59
, pp. 211-224
-
-
Chan, K.C.1
-
8
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson, S. J. et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med 368, 1199-1209, doi: 10.1056/NEJMoa1213261 (2013).
-
(2013)
N Engl J Med
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
-
9
-
-
84946559772
-
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
-
Murtaza, M. et al. Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer. Nat Commun 6, 8760, doi: 10.1038/ncomms9760 (2015).
-
(2015)
Nat Commun
, vol.6
, pp. 8760
-
-
Murtaza, M.1
-
10
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
-
Murtaza, M. et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 497, 108-112, doi: 10.1038/nature12065 (2013).
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
-
11
-
-
84903218109
-
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
-
Newman, A. M. et al. An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat Med 20, 548-554, doi: 10.1038/nm.3519 (2014).
-
(2014)
Nat Med
, vol.20
, pp. 548-554
-
-
Newman, A.M.1
-
12
-
-
84863000299
-
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
-
Diaz, L. A., Jr. et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 486, 537-540, doi: 10.1038/nature11219 (2012).
-
(2012)
Nature
, vol.486
, pp. 537-540
-
-
Diaz, L.A.1
-
13
-
-
84942521073
-
Early prediction of response to tyrosine kinase inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients
-
Marchetti, A. et al. Early Prediction of Response to Tyrosine Kinase Inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients. J Thorac Oncol 10, 1437-1443, doi: 10.1097/JTO.0000000000000643 (2015).
-
(2015)
J Thorac Oncol
, vol.10
, pp. 1437-1443
-
-
Marchetti, A.1
-
14
-
-
84902495614
-
Detection of EGFR mutations in the plasma of patients with lung adenocarcinoma for real-Time monitoring of therapeutic response to tyrosine kinase inhibitors?
-
Marcq, M., Vallee, A., Bizieux, A. & Denis, M. G. Detection of EGFR mutations in the plasma of patients with lung adenocarcinoma for real-Time monitoring of therapeutic response to tyrosine kinase inhibitors? J Thorac Oncol 9, e49-e50, doi: 10.1097/JTO.0000000000000134 (2014).
-
(2014)
J Thorac Oncol
, vol.9
, pp. e49-e50
-
-
Marcq, M.1
Vallee, A.2
Bizieux, A.3
Denis, M.G.4
-
15
-
-
84862999938
-
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
-
Misale, S. et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 486, 532-536, doi: 10.1038/nature11156 (2012).
-
(2012)
Nature
, vol.486
, pp. 532-536
-
-
Misale, S.1
-
16
-
-
84896539307
-
Noninvasive detection of response and resistance in EGFR-mutant lung cancer using quantitative nextgeneration genotyping of cell-free plasma DNA
-
Oxnard, G. R. et al. Noninvasive detection of response and resistance in EGFR-mutant lung cancer using quantitative nextgeneration genotyping of cell-free plasma DNA. Clin Cancer Res 20, 1698-1705, doi: 10.1158/1078-0432.CCR-13-2482 (2014).
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1698-1705
-
-
Oxnard, G.R.1
-
17
-
-
84930755018
-
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M
-
Thress, K. S. et al. Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M. Nat Med 21, 560-562, doi: 10.1038/nm.3854 (2015).
-
(2015)
Nat Med
, vol.21
, pp. 560-562
-
-
Thress, K.S.1
-
18
-
-
84926312116
-
Microdroplet digital PCR: Detection and quantitation of biomarkers in archived tissue and serial plasma samples in patients with lung cancer
-
Gao, F. et al. Microdroplet digital PCR: detection and quantitation of biomarkers in archived tissue and serial plasma samples in patients with lung cancer. J Thorac Oncol 10, 212-217, doi: 10.1097/JTO.0000000000000349 (2015).
-
(2015)
J Thorac Oncol
, vol.10
, pp. 212-217
-
-
Gao, F.1
-
19
-
-
84863967346
-
Ultrasensitive measurement of hotspot mutations in tumor DNA in blood using error-suppressed multiplexed deep sequencing
-
Narayan, A. et al. Ultrasensitive measurement of hotspot mutations in tumor DNA in blood using error-suppressed multiplexed deep sequencing. Cancer Res 72, 3492-3498, doi: 10.1158/0008-5472.CAN-11-4037 (2012).
-
(2012)
Cancer Res
, vol.72
, pp. 3492-3498
-
-
Narayan, A.1
-
20
-
-
84958569032
-
Plasma EGFR T790M ctDNA status is associated with clinical outcome in advanced NSCLC patients with acquired EGFR-TKI resistance
-
Zheng, D. et al. Plasma EGFR T790M ctDNA status is associated with clinical outcome in advanced NSCLC patients with acquired EGFR-TKI resistance. Sci Rep 6, 20913, doi: 10.1038/srep20913 (2016).
-
(2016)
Sci Rep
, vol.6
, pp. 20913
-
-
Zheng, D.1
-
21
-
-
28044468634
-
Detection and quantification of mutations in the plasma of patients with colorectal tumors
-
Diehl, F. et al. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proc Natl Acad Sci USA 102, 16368-16373, doi: 10.1073/pnas.0507904102 (2005).
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16368-16373
-
-
Diehl, F.1
-
22
-
-
84925338452
-
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
-
Jiang, P. et al. Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients. Proc Natl Acad Sci USA 112, E1317-E1325, doi: 10.1073/pnas.1500076112 (2015).
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E1317-E1325
-
-
Jiang, P.1
-
23
-
-
80052436485
-
High fragmentation characterizes tumour-derived circulating DNA
-
Mouliere, F. et al. High fragmentation characterizes tumour-derived circulating DNA. PLoS One 6, e23418, doi: 10.1371/journal. pone.0023418 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e23418
-
-
Mouliere, F.1
-
24
-
-
84914703538
-
Quantification and dynamic monitoring of EGFR T790M in plasma cell-free DNA by digital PCR for prognosis of EGFR-TKI treatment in advanced NSCLC
-
Wang, Z. et al. Quantification and dynamic monitoring of EGFR T790M in plasma cell-free DNA by digital PCR for prognosis of EGFR-TKI treatment in advanced NSCLC. PLoS One 9, e110780, doi: 10.1371/journal.pone.0110780 (2014).
-
(2014)
PLoS One
, vol.9
, pp. e110780
-
-
Wang, Z.1
-
25
-
-
52449101985
-
A phase II pharmacodynamic study of erlotinib in patients with advanced non-small cell lung cancer previously treated with platinum-based chemotherapy
-
Felip, E. et al. A phase II pharmacodynamic study of erlotinib in patients with advanced non-small cell lung cancer previously treated with platinum-based chemotherapy. Clin Cancer Res 14, 3867-3874, doi: 10.1158/1078-0432.CCR-07-5186 (2008).
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3867-3874
-
-
Felip, E.1
-
26
-
-
35648965243
-
Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas
-
Gong, Y. et al. Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas. PLoS Med 4, e294, doi: 10.1371/journal.pmed.0040294 (2007).
-
(2007)
PLoS Med
, vol.4
, pp. e294
-
-
Gong, Y.1
-
27
-
-
0032246317
-
Radiation-induced blood-brain barrier changes: Pathophysiological mechanisms and clinical implications
-
dAvella, D. et al. Radiation-induced blood-brain barrier changes: pathophysiological mechanisms and clinical implications. Acta Neurochir Suppl 71, 282-284 (1998).
-
(1998)
Acta Neurochir Suppl
, vol.71
, pp. 282-284
-
-
Davella, D.1
-
28
-
-
0035889349
-
Improved efficacy of chemotherapy for glioblastoma by radiation-induced opening of blood-brain barrier: Clinical results
-
Qin, D. et al. Improved efficacy of chemotherapy for glioblastoma by radiation-induced opening of blood-brain barrier: clinical results. Int J Radiat Oncol Biol Phys 51, 959-962 (2001).
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 959-962
-
-
Qin, D.1
-
29
-
-
84936748494
-
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
-
Siravegna, G. et al. Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients. Nat Med 21, 795-801, doi: 10.1038/nm.3870 (2015).
-
(2015)
Nat Med
, vol.21
, pp. 795-801
-
-
Siravegna, G.1
-
30
-
-
84918789657
-
Monitoring of epidermal growth factor receptor tyrosine kinase inhibitor-sensitizing and resistance mutations in the plasma DNA of patients with advanced non-small cell lung cancer during treatment with erlotinib
-
Sorensen, B. S. et al. Monitoring of epidermal growth factor receptor tyrosine kinase inhibitor-sensitizing and resistance mutations in the plasma DNA of patients with advanced non-small cell lung cancer during treatment with erlotinib. Cancer 120, 3896-3901, doi: 10.1002/cncr.28964 (2014).
-
(2014)
Cancer
, vol.120
, pp. 3896-3901
-
-
Sorensen, B.S.1
-
31
-
-
51349141191
-
Circulating mutant DNA to assess tumor dynamics
-
Diehl, F. et al. Circulating mutant DNA to assess tumor dynamics. Nat Med 14, 985-990, doi: 10.1038/nm.1789 (2008).
-
(2008)
Nat Med
, vol.14
, pp. 985-990
-
-
Diehl, F.1
-
32
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran, S. et al. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 359, 366-377, doi: 10.1056/NEJMoa0800668 (2008).
-
(2008)
N Engl J Med
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
-
33
-
-
79952264325
-
Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-Treated advanced non-small-cell lung cancer patients with EGFR mutations
-
Rosell, R. et al. Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-Treated advanced non-small-cell lung cancer patients with EGFR mutations. Clin Cancer Res 17, 1160-1168, doi: 10.1158/1078-0432.CCR-10-2158 (2011).
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1160-1168
-
-
Rosell, R.1
-
34
-
-
84941309223
-
Cell-free DNA: Preanalytical variables
-
Bronkhorst, A. J., Aucamp, J. & Pretorius, P. J. Cell-free DNA: Preanalytical variables. Clin Chim Acta 450, 243-253, doi: 10.1016/j. cca.2015.08.028 (2015).
-
(2015)
Clin Chim Acta
, vol.450
, pp. 243-253
-
-
Bronkhorst, A.J.1
Aucamp, J.2
Pretorius, P.J.3
-
35
-
-
72649092170
-
Is the role of circulating DNA as a biomarker of cancer being prematurely overrated?
-
van der Vaart, M. & Pretorius, P. J. Is the role of circulating DNA as a biomarker of cancer being prematurely overrated? Clin Biochem 43, 26-36, doi: 10.1016/j.clinbiochem.2009.08.027 (2010).
-
(2010)
Clin Biochem
, vol.43
, pp. 26-36
-
-
Van Der Vaart, M.1
Pretorius, P.J.2
|