Ultrasensitive measurement of hotspot mutations in tumor DNA in blood using error-suppressed multiplexed deep sequencing

Cancer Research

Volumn 72, Issue 14, 2012, Pages 3492-3498

  Narayan, Azeet ^a   Carriero, Nicholas J ^b   Gettinger, Scott N ^a   Kluytenaar, Jeannie ^a   Kozak, Kevin R ^c   Yock, Torunn I ^d   Muscato, Nicole E ^e   Ugarelli, Pedro ^e   Decker, Roy H ^a   Patel, Abhijit A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yale University   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e Lawrence and Memorial Hospital ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULATING TUMOR DNA; DNA FRAGMENT; GENOMIC DNA; TUMOR MARKER; UNCLASSIFIED DRUG;

ARTICLE; BLOOD ANALYSIS; CANCER CHEMOTHERAPY; CANCER GENETICS; CANCER RADIOTHERAPY; CANCER SURGERY; DNA DETERMINATION; DNA SEQUENCE; ERROR SUPPRESSED DEEP SEQUENCING; GENE AMPLIFICATION; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; TUMOR CELL;

CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DNA, NEOPLASM; FEMALE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LUNG NEOPLASMS; MALE; MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 84863967346     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-4037     Document Type: Article

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