-
1
-
-
39449103059
-
The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America
-
B.Spellberg, R.Guidos, D.Gilbert, et al. The epidemic of antibiotic-resistant infections:a call to action for the medical community from the Infectious Diseases Society of America. Clin Infect Dis. 2008;46(2):155–164.
-
(2008)
Clin Infect Dis
, vol.46
, Issue.2
, pp. 155-164
-
-
Spellberg, B.1
Guidos, R.2
Gilbert, D.3
-
2
-
-
84878278251
-
10 x ‘20 progress–development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America
-
H.W.Boucher, G.H.Talbot, D.K.BenjaminJr., et al. 10 x ‘20 progress–development of new drugs active against gram-negative bacilli:an update from the Infectious Diseases Society of America. Clin Infect Dis. 2013;56(12):1685–1694.
-
(2013)
Clin Infect Dis
, vol.56
, Issue.12
, pp. 1685-1694
-
-
Boucher, H.W.1
Talbot, G.H.2
Benjamin, D.K.3
-
3
-
-
57749107808
-
Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America
-
H.W.Boucher, G.H.Talbot, J.S.Bradley, et al. Bad bugs, no drugs:no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis. 2009;48(1):1–12.
-
(2009)
Clin Infect Dis
, vol.48
, Issue.1
, pp. 1-12
-
-
Boucher, H.W.1
Talbot, G.H.2
Bradley, J.S.3
-
4
-
-
81155162497
-
Diazabicyclooctanes (DBOs): a potent new class of non-beta-lactam beta-lactamase inhibitors
-
K.Coleman Diazabicyclooctanes (DBOs):a potent new class of non-beta-lactam beta-lactamase inhibitors. Curr Opin Microbiol. 2011;14(5):550–555.
-
(2011)
Curr Opin Microbiol
, vol.14
, Issue.5
, pp. 550-555
-
-
Coleman, K.1
-
5
-
-
84882239083
-
The ABCD’s of beta-lactamase nomenclature
-
K.Bush. The ABCD’s of beta-lactamase nomenclature. J Infect Chemother. 2013;19(4):549–559.
-
(2013)
J Infect Chemother
, vol.19
, Issue.4
, pp. 549-559
-
-
Bush, K.1
-
6
-
-
84872858103
-
Proliferation and significance of clinically relevant beta-lactamases
-
K.Bush. Proliferation and significance of clinically relevant beta-lactamases. Ann N Y Acad Sci. 2013;1277:84–90.
-
(2013)
Ann N Y Acad Sci
, vol.1277
, pp. 84-90
-
-
Bush, K.1
-
7
-
-
84882270910
-
Carbapenemases: partners in crime
-
K.Bush. Carbapenemases:partners in crime. J Global Antimicrob Resist. 2013;1(1):7–16.
-
(2013)
J Global Antimicrob Resist
, vol.1
, Issue.1
, pp. 7-16
-
-
Bush, K.1
-
8
-
-
84893488293
-
Widespread dissemination of CTX-M-15 genotype extended-spectrum-beta-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States
-
L.F.Chen, J.T.Freeman, B.Nicholson, et al. Widespread dissemination of CTX-M-15 genotype extended-spectrum-beta-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States. Antimicrob Agents Chemother. 2014;58(2):1200–1202.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.2
, pp. 1200-1202
-
-
Chen, L.F.1
Freeman, J.T.2
Nicholson, B.3
-
9
-
-
84906099443
-
A new clone sweeps clean: the enigmatic emergence of Escherichia coli sequence type 131
-
R.Banerjee, J.R.Johnson. A new clone sweeps clean:the enigmatic emergence of Escherichia coli sequence type 131. Antimicrob Agents Chemother. 2014;58(9):4997–5004.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.9
, pp. 4997-5004
-
-
Banerjee, R.1
Johnson, J.R.2
-
10
-
-
84898814306
-
Global dissemination of a multidrug resistant Escherichia coli clone
-
N.K.Petty, N.L.Ben Zakour, M.Stanton-Cook, et al. Global dissemination of a multidrug resistant Escherichia coli clone. Proc Natl Acad Sci U S A. 2014;111(15):5694–5699.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.15
, pp. 5694-5699
-
-
Petty, N.K.1
Ben Zakour, N.L.2
Stanton-Cook, M.3
-
11
-
-
74249108028
-
Three decades of beta-lactamase inhibitors
-
S.M.Drawz, R.A.Bonomo. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010;23(1):160–201.
-
(2010)
Clin Microbiol Rev
, vol.23
, Issue.1
, pp. 160-201
-
-
Drawz, S.M.1
Bonomo, R.A.2
-
12
-
-
84946567642
-
A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens
-
K.Bush. A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015;46(5):483–493.
-
(2015)
Int J Antimicrob Agents
, vol.46
, Issue.5
, pp. 483-493
-
-
Bush, K.1
-
13
-
-
84911483559
-
Ceftolozane/tazobactam (CXA 201) for the treatment of intra-abdominal infections
-
E.Maseda, L.Aguilar, M.-J.Gimenez, et al. Ceftolozane/tazobactam (CXA 201) for the treatment of intra-abdominal infections. Expert Rev Anti Infect Ther. 2014;12(11):1311–1324.
-
(2014)
Expert Rev Anti Infect Ther
, vol.12
, Issue.11
, pp. 1311-1324
-
-
Maseda, E.1
Aguilar, L.2
Gimenez, M.-J.3
-
14
-
-
0020041206
-
Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa
-
H.C.Neu, P.Labthavikul. Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1982;21(1):11–18.
-
(1982)
Antimicrob Agents Chemother
, vol.21
, Issue.1
, pp. 11-18
-
-
Neu, H.C.1
Labthavikul, P.2
-
15
-
-
84894441748
-
Ceftazidime-avibactam: an evidence-based review of its pharmacology and potential use in the treatment of gram-negative bacterial infections
-
P.Lagace-Wiens, A.Walkty, J.A.Karlowsky. Ceftazidime-avibactam:an evidence-based review of its pharmacology and potential use in the treatment of gram-negative bacterial infections. Core Evid. 2014;9:13–25.
-
(2014)
Core Evid
, vol.9
, pp. 13-25
-
-
Lagace-Wiens, P.1
Walkty, A.2
Karlowsky, J.A.3
-
16
-
-
84872732888
-
Ceftazidime-avibactam: a novel cephalosporin/beta-lactamase inhibitor combination
-
G.G.Zhanel, C.D.Lawson, H.Adam, et al. Ceftazidime-avibactam:a novel cephalosporin/beta-lactamase inhibitor combination. Drugs. 2013;73(2):159–177.
-
(2013)
Drugs
, vol.73
, Issue.2
, pp. 159-177
-
-
Zhanel, G.G.1
Lawson, C.D.2
Adam, H.3
-
17
-
-
84863905057
-
Avibactam is a covalent, reversible, non-beta-lactam beta-lactamase inhibitor
-
D.E.Ehmann, H.Jahic, P.L.Ross, et al. Avibactam is a covalent, reversible, non-beta-lactam beta-lactamase inhibitor. Proc Natl Acad Sci U S A. 2012;109(29):11663–11668.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.29
, pp. 11663-11668
-
-
Ehmann, D.E.1
Jahic, H.2
Ross, P.L.3
-
18
-
-
78649683457
-
Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor
-
T.Stachyra, M.C.Pechereau, J.M.Bruneau, et al. Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor. Antimicrob Agents Chemother. 2010;54(12):5132–5138.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.12
, pp. 5132-5138
-
-
Stachyra, T.1
Pechereau, M.C.2
Bruneau, J.M.3
-
19
-
-
4444347175
-
In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor
-
A.Bonnefoy, C.Dupuis-Hamelin, V.Steier, et al. In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor. J Antimicrob Chemother. 2004;54(2):410–417.
-
(2004)
J Antimicrob Chemother
, vol.54
, Issue.2
, pp. 410-417
-
-
Bonnefoy, A.1
Dupuis-Hamelin, C.2
Steier, V.3
-
20
-
-
67650718178
-
In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and enterobacteriaceae expressing KPC carbapenemases
-
T.Stachyra, P.Levasseur, M.C.Pechereau, et al. In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and enterobacteriaceae expressing KPC carbapenemases. J Antimicrob Chemother. 2009;64(2):326–329.
-
(2009)
J Antimicrob Chemother
, vol.64
, Issue.2
, pp. 326-329
-
-
Stachyra, T.1
Levasseur, P.2
Pechereau, M.C.3
-
21
-
-
84977964862
-
Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects
-
S.Das, J.Li, J.Armstrong, et al. Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects. Pharmacol Res Perspect. 2015;3(5):e00172.
-
(2015)
Pharmacol Res Perspect
, vol.3
, Issue.5
, pp. e00172
-
-
Das, S.1
Li, J.2
Armstrong, J.3
-
22
-
-
84940007604
-
Safety and pharmacokinetics of single and multiple ascending doses of avibactam alone and in combination with ceftazidime in healthy male volunteers: results of two randomized, placebo-controlled studies
-
H.Merdjan, M.Rangaraju, A.Tarral. Safety and pharmacokinetics of single and multiple ascending doses of avibactam alone and in combination with ceftazidime in healthy male volunteers:results of two randomized, placebo-controlled studies. Clin Drug Investig. 2015;35(5):307–317.
-
(2015)
Clin Drug Investig
, vol.35
, Issue.5
, pp. 307-317
-
-
Merdjan, H.1
Rangaraju, M.2
Tarral, A.3
-
23
-
-
84937627900
-
Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers
-
N.Tominaga, T.Edeki, J.Li, et al. Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers. J Infect Chemother. 2015;21(8):551–558.
-
(2015)
J Infect Chemother
, vol.21
, Issue.8
, pp. 551-558
-
-
Tominaga, N.1
Edeki, T.2
Li, J.3
-
24
-
-
84957426156
-
A randomized, phase I study to assess the safety, tolerability and pharmacokinetics of ceftazidime-avibactam in healthy Chinese subjects
-
J.Li, M.Learoyd, F.Qiu, et al. A randomized, phase I study to assess the safety, tolerability and pharmacokinetics of ceftazidime-avibactam in healthy Chinese subjects. Clin Drug Investig. 2016;36(2):119–126.
-
(2016)
Clin Drug Investig
, vol.36
, Issue.2
, pp. 119-126
-
-
Li, J.1
Learoyd, M.2
Qiu, F.3
-
25
-
-
84988397380
-
-
Avycaz (Ceftazidime-Avibactam). Package insert. Cincinnati, OH:Forest Pharmaceuticals; 2015.• Package insert.
-
(2015)
-
-
-
26
-
-
84906074469
-
Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-avibactam against beta-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa
-
T.R.Keepers, M.Gomez, C.Celeri, et al. Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-avibactam against beta-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa. Antimicrob Agents Chemother. 2014;58(9):5297–5305.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.9
, pp. 5297-5305
-
-
Keepers, T.R.1
Gomez, M.2
Celeri, C.3
-
27
-
-
84896844160
-
Efficacies of ceftazidime-avibactam and ceftazidime against pseudomonas aeruginosa in a murine lung infection model
-
S.T.Housman, J.L.Crandon, W.W.Nichols, et al. Efficacies of ceftazidime-avibactam and ceftazidime against pseudomonas aeruginosa in a murine lung infection model. Antimicrob Agents Chemother. 2014;58(3):1365–1371.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.3
, pp. 1365-1371
-
-
Housman, S.T.1
Crandon, J.L.2
Nichols, W.W.3
-
28
-
-
80054898230
-
-
Hoboken: CRC Press
-
M.L.Grayson, S.M.Crowe, J.S.McCarthy, et al. Kucers’ the use of antibiotics sixth edition, a clinical review of antibacterial, antifungal and antiviral drugs. Hoboken:CRC Press; 2010.
-
(2010)
Kucers’ the use of antibiotics sixth edition, a clinical review of antibacterial, antifungal and antiviral drugs
-
-
Grayson, M.L.1
Crowe, S.M.2
McCarthy, J.S.3
-
29
-
-
34547422759
-
Carbapenemases: the versatile beta-lactamases
-
A.M.Queenan, K.Bush. Carbapenemases:the versatile beta-lactamases. Clin Microbiol Rev. 2007;20(3):440–458.
-
(2007)
Clin Microbiol Rev
, vol.20
, Issue.3
, pp. 440-458
-
-
Queenan, A.M.1
Bush, K.2
-
30
-
-
0031952586
-
Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men
-
W.A.Craig. Pharmacokinetic/pharmacodynamic parameters:rationale for antibacterial dosing of mice and men. Clin Infect Dis. 1998;26(1):1–10.
-
(1998)
Clin Infect Dis
, vol.26
, Issue.1
, pp. 1-10
-
-
Craig, W.A.1
-
31
-
-
84860188286
-
Novel modeling framework to guide design of optimal dosing strategies for beta-lactamase inhibitors
-
P.Bhagunde, K.T.Chang, E.B.Hirsch, et al. Novel modeling framework to guide design of optimal dosing strategies for beta-lactamase inhibitors. Antimicrob Agents Chemother. 2012;56(5):2237–2240.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.5
, pp. 2237-2240
-
-
Bhagunde, P.1
Chang, K.T.2
Hirsch, E.B.3
-
32
-
-
84901260013
-
Activities of ceftazidime and avibactam against beta-lactamase-producing Enterobacteriaceae in a hollow-fiber pharmacodynamic model
-
K.Coleman, P.Levasseur, A.M.Girard, et al. Activities of ceftazidime and avibactam against beta-lactamase-producing Enterobacteriaceae in a hollow-fiber pharmacodynamic model. Antimicrob Agents Chemother. 2014;58(6):3366–3372.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.6
, pp. 3366-3372
-
-
Coleman, K.1
Levasseur, P.2
Girard, A.M.3
-
33
-
-
84921784867
-
In vitro activity of ceftazidime-avibactam combination in in vitro checkerboard assays
-
J.Berkhout, M.J.Melchers, A.C.Van Mil, et al. In vitro activity of ceftazidime-avibactam combination in in vitro checkerboard assays. Antimicrob Agents Chemother. 2015;59(2):1138–1144.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.2
, pp. 1138-1144
-
-
Berkhout, J.1
Melchers, M.J.2
Van Mil, A.C.3
-
34
-
-
84911896976
-
Microbiological interaction studies between ceftazidime-avibactam and pulmonary surfactant and between ceftazidime-avibactam and antibacterial agents of other classes
-
J.Dallow, L.G.Otterson, M.D.Huband, et al. Microbiological interaction studies between ceftazidime-avibactam and pulmonary surfactant and between ceftazidime-avibactam and antibacterial agents of other classes. Int J Antimicrob Agents. 2014;44(6):552–556.
-
(2014)
Int J Antimicrob Agents
, vol.44
, Issue.6
, pp. 552-556
-
-
Dallow, J.1
Otterson, L.G.2
Huband, M.D.3
-
36
-
-
84988355754
-
European committee on antimicrobial susceptibility testing: clinical breakpoints
-
European Society of Clinical Microbiology and Infectious Diseases
-
EUCAST. European committee on antimicrobial susceptibility testing:clinical breakpoints. EUCAST. European Society of Clinical Microbiology and Infectious Diseases; 2016 Available at www.eucast.org
-
(2016)
EUCAST
-
-
-
37
-
-
84940186561
-
Validation of sensititre dry-form broth microdilution panels for susceptibility testing of ceftazidime-avibactam, a broad-spectrum-beta-lactamase inhibitor combination
-
R.N.Jones, N.M.Holliday, K.M.Krause. Validation of sensititre dry-form broth microdilution panels for susceptibility testing of ceftazidime-avibactam, a broad-spectrum-beta-lactamase inhibitor combination. Antimicrob Agents Chemother. 2015;59(8):5036–5039.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.8
, pp. 5036-5039
-
-
Jones, R.N.1
Holliday, N.M.2
Krause, K.M.3
-
39
-
-
84896833758
-
Antimicrobial activity of ceftazidime-avibactam against Gram-negative organisms collected from U.S. medical centers in 2012
-
H.S.Sader, M.Castanheira, R.K.Flamm, et al. Antimicrobial activity of ceftazidime-avibactam against Gram-negative organisms collected from U.S. medical centers in 2012. Antimicrob Agents Chemother. 2014;58(3):1684–1692.• Large US-based microbiologic survey demonstrating in vitro activity of CTZ–AVI against a wide variety of Gram-negative organisms.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.3
, pp. 1684-1692
-
-
Sader, H.S.1
Castanheira, M.2
Flamm, R.K.3
-
40
-
-
84903893512
-
Ceftazidime/avibactam activity tested against Gram-negative bacteria isolated from bloodstream, pneumonia, intra-abdominal and urinary tract infections in US medical centres (2012)
-
R.K.Flamm, D.J.Farrell, H.S.Sader, et al. Ceftazidime/avibactam activity tested against Gram-negative bacteria isolated from bloodstream, pneumonia, intra-abdominal and urinary tract infections in US medical centres (2012). J Antimicrob Chemother. 2014;69(6):1589–1598.
-
(2014)
J Antimicrob Chemother
, vol.69
, Issue.6
, pp. 1589-1598
-
-
Flamm, R.K.1
Farrell, D.J.2
Sader, H.S.3
-
41
-
-
84893488813
-
Contemporary diversity of beta-lactamases among Enterobacteriaceae in the nine U.S. census regions and ceftazidime-avibactam activity tested against isolates producing the most prevalent beta-lactamase groups
-
M.Castanheira, S.E.Farrell, K.M.Krause, et al. Contemporary diversity of beta-lactamases among Enterobacteriaceae in the nine U.S. census regions and ceftazidime-avibactam activity tested against isolates producing the most prevalent beta-lactamase groups. Antimicrob Agents Chemother. 2014;58(2):833–838.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.2
, pp. 833-838
-
-
Castanheira, M.1
Farrell, S.E.2
Krause, K.M.3
-
42
-
-
84929587395
-
Ceftazidime-avibactam activity tested against Enterobacteriaceae isolates from U.S. hospitals (2011 to 2013) and characterization of beta-lactamase-producing strains
-
M.Castanheira, J.C.Mills, S.E.Costello, et al. Ceftazidime-avibactam activity tested against Enterobacteriaceae isolates from U.S. hospitals (2011 to 2013) and characterization of beta-lactamase-producing strains. Antimicrob Agents Chemother. 2015;59(6):3509–3517.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.6
, pp. 3509-3517
-
-
Castanheira, M.1
Mills, J.C.2
Costello, S.E.3
-
43
-
-
84927574043
-
Ceftazidime-avibactam and comparator agents tested against urinary tract isolates from a global surveillance program (2011)
-
R.K.Flamm, H.S.Sader, D.J.Farrell, et al. Ceftazidime-avibactam and comparator agents tested against urinary tract isolates from a global surveillance program (2011). Diagn Microbiol Infect Dis. 2014;80(3):233–238.
-
(2014)
Diagn Microbiol Infect Dis
, vol.80
, Issue.3
, pp. 233-238
-
-
Flamm, R.K.1
Sader, H.S.2
Farrell, D.J.3
-
44
-
-
84947026302
-
Ceftazidime-avibactam activity when tested against ceftazidime-nonsusceptible Citrobacter spp., Enterobacter spp., Serratia marcescens, and Pseudomonas aeruginosa from Unites States medical centers (2011-2014)
-
H.S.Sader, M.Castanheira, D.J.Farrell, et al. Ceftazidime-avibactam activity when tested against ceftazidime-nonsusceptible Citrobacter spp., Enterobacter spp., Serratia marcescens, and Pseudomonas aeruginosa from Unites States medical centers (2011-2014). Diagn Microbiol Infect Dis. 2015;83(4):389–394.
-
(2015)
Diagn Microbiol Infect Dis
, vol.83
, Issue.4
, pp. 389-394
-
-
Sader, H.S.1
Castanheira, M.2
Farrell, D.J.3
-
45
-
-
84934963355
-
Ceftazidime/avibactam tested against Gram-negative bacteria from intensive care unit (ICU) and non-ICU patients, including those with ventilator-associated pneumonia
-
H.S.Sader, M.Castanheira, R.K.Flamm, et al. Ceftazidime/avibactam tested against Gram-negative bacteria from intensive care unit (ICU) and non-ICU patients, including those with ventilator-associated pneumonia. Int J Antimicrob Agents. 2015;46(1):53–59.
-
(2015)
Int J Antimicrob Agents
, vol.46
, Issue.1
, pp. 53-59
-
-
Sader, H.S.1
Castanheira, M.2
Flamm, R.K.3
-
46
-
-
84929583498
-
Ceftazidime-avibactam activity against multidrug-resistant Pseudomonas aeruginosa isolated in U.S. medical centers in 2012 and 2013
-
H.S.Sader, M.Castanheira, R.E.Mendes, et al. Ceftazidime-avibactam activity against multidrug-resistant Pseudomonas aeruginosa isolated in U.S. medical centers in 2012 and 2013. Antimicrob Agents Chemother. 2015;59(6):3656–3659.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.6
, pp. 3656-3659
-
-
Sader, H.S.1
Castanheira, M.2
Mendes, R.E.3
-
47
-
-
84929615655
-
In vitro activity of ceftazidime-avibactam against 338 molecularly characterized gentamicin-nonsusceptible gram-negative clinical isolates obtained from patients in Canadian hospitals
-
A.J.Denisuik, J.A.Karlowsky, T.Denisuik, et al. In vitro activity of ceftazidime-avibactam against 338 molecularly characterized gentamicin-nonsusceptible gram-negative clinical isolates obtained from patients in Canadian hospitals. Antimicrob Agents Chemother. 2015;59(6):3623–3626.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.6
, pp. 3623-3626
-
-
Denisuik, A.J.1
Karlowsky, J.A.2
Denisuik, T.3
-
48
-
-
84920099992
-
Avibactam reverts the ceftazidime MIC90 of European gram-negative bacterial clinical isolates to the epidemiological cut-off value
-
R.K.Flamm, G.G.Stone, H.S.Sader, et al. Avibactam reverts the ceftazidime MIC90 of European gram-negative bacterial clinical isolates to the epidemiological cut-off value. J Chemother. 2014;26(6):333–338.
-
(2014)
J Chemother
, vol.26
, Issue.6
, pp. 333-338
-
-
Flamm, R.K.1
Stone, G.G.2
Sader, H.S.3
-
49
-
-
84857173233
-
In vitro antibacterial activity of the ceftazidime-avibactam (NXL104) combination against Pseudomonas aeruginosa clinical isolates
-
P.Levasseur, A.M.Girard, M.Claudon, et al. In vitro antibacterial activity of the ceftazidime-avibactam (NXL104) combination against Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother. 2012;56(3):1606–1608.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.3
, pp. 1606-1608
-
-
Levasseur, P.1
Girard, A.M.2
Claudon, M.3
-
50
-
-
82955187694
-
In vitro activity of avibactam (NXL104) in combination with beta-lactams against gram-negative bacteria, including OXA-48 beta-lactamase-producing Klebsiella pneumoniae
-
Z.Aktas, C.Kayacan, O.Oncul. In vitro activity of avibactam (NXL104) in combination with beta-lactams against gram-negative bacteria, including OXA-48 beta-lactamase-producing Klebsiella pneumoniae. Int J Antimicrob Agents. 2012;39(1):86–89.
-
(2012)
Int J Antimicrob Agents
, vol.39
, Issue.1
, pp. 86-89
-
-
Aktas, Z.1
Kayacan, C.2
Oncul, O.3
-
51
-
-
79955537450
-
Activity of NXL104 in combination with beta-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing class A extended-spectrum beta-lactamases and class C beta-lactamases
-
P.R.Lagace-Wiens, F.Tailor, P.Simner, et al. Activity of NXL104 in combination with beta-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing class A extended-spectrum beta-lactamases and class C beta-lactamases. Antimicrob Agents Chemother. 2011;55(5):2434–2437.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.5
, pp. 2434-2437
-
-
Lagace-Wiens, P.R.1
Tailor, F.2
Simner, P.3
-
52
-
-
67749143907
-
In vitro activity of NXL104 in combination with beta-lactams against Klebsiella pneumoniae isolates producing KPC carbapenemases
-
A.Endimiani, Y.Choudhary, R.A.Bonomo. In vitro activity of NXL104 in combination with beta-lactams against Klebsiella pneumoniae isolates producing KPC carbapenemases. Antimicrob Agents Chemother. 2009;53(8):3599–3601.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.8
, pp. 3599-3601
-
-
Endimiani, A.1
Choudhary, Y.2
Bonomo, R.A.3
-
53
-
-
84896832898
-
In vitro activities of ceftazidime-avibactam and aztreonam-avibactam against 372 gram-negative bacilli collected in 2011 and 2012 from 11 teaching hospitals in China
-
X.Wang, F.Zhang, C.Zhao, et al. In vitro activities of ceftazidime-avibactam and aztreonam-avibactam against 372 gram-negative bacilli collected in 2011 and 2012 from 11 teaching hospitals in China. Antimicrob Agents Chemother. 2014;58(3):1774–1778.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.3
, pp. 1774-1778
-
-
Wang, X.1
Zhang, F.2
Zhao, C.3
-
54
-
-
84928893993
-
In vitro antibacterial activity of the ceftazidime-avibactam combination against enterobacteriaceae, including strains with well-characterized beta-lactamases
-
P.Levasseur, A.M.Girard, C.Miossec, et al. In vitro antibacterial activity of the ceftazidime-avibactam combination against enterobacteriaceae, including strains with well-characterized beta-lactamases. Antimicrob Agents Chemother. 2015;59(4):1931–1934.• Microbiologic study demonstrating restoration of activity of ceftazidime following addition of avibactam in resistant Enterobacteriaceae.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.4
, pp. 1931-1934
-
-
Levasseur, P.1
Girard, A.M.2
Miossec, C.3
-
55
-
-
84947867553
-
Activity of temocillin, mecillinam, ceftazidime, and ceftazidime/avibactam against carbapenem-nonsusceptible Enterobacteriaceae without carbapenemase production
-
N.T.Mutters, S.Zimmermann, M.Kaase, et al. Activity of temocillin, mecillinam, ceftazidime, and ceftazidime/avibactam against carbapenem-nonsusceptible Enterobacteriaceae without carbapenemase production. Eur J Clin Microbiol Infect Dis. 2015;34(12):2429–2437.
-
(2015)
Eur J Clin Microbiol Infect Dis
, vol.34
, Issue.12
, pp. 2429-2437
-
-
Mutters, N.T.1
Zimmermann, S.2
Kaase, M.3
-
56
-
-
84955294377
-
Activity of ceftazidime-avibactam against fluoroquinolone-resistant Enterobacteriaceae and Pseudomonas aeruginosa
-
C.Pitart, F.Marco, T.A.Keating, et al. Activity of ceftazidime-avibactam against fluoroquinolone-resistant Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2015;59(6):3059–3065.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.6
, pp. 3059-3065
-
-
Pitart, C.1
Marco, F.2
Keating, T.A.3
-
57
-
-
78650636489
-
Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae
-
D.M.Livermore, S.Mushtaq, M.Warner, et al. Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae. Antimicrob Agents Chemother. 2011;55(1):390–394.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.1
, pp. 390-394
-
-
Livermore, D.M.1
Mushtaq, S.2
Warner, M.3
-
58
-
-
79956326529
-
In vitro activity of ceftazidime combined with NXL104 versus Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals (CANWARD 2009 study)
-
A.Walkty, M.DeCorby, P.R.Lagace-Wiens, et al. In vitro activity of ceftazidime combined with NXL104 versus Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals (CANWARD 2009 study). Antimicrob Agents Chemother. 2011;55(6):2992–2994.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.6
, pp. 2992-2994
-
-
Walkty, A.1
DeCorby, M.2
Lagace-Wiens, P.R.3
-
59
-
-
77957862993
-
In vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermenters
-
S.Mushtaq, M.Warner, D.M.Livermore. In vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermenters. J Antimicrob Chemother. 2010;65(11):2376–2381.• Microbiologic study demonstrating in-vitro resistance to CTZ–AVI via non-β-lactamase mechanisms.
-
(2010)
J Antimicrob Chemother
, vol.65
, Issue.11
, pp. 2376-2381
-
-
Mushtaq, S.1
Warner, M.2
Livermore, D.M.3
-
60
-
-
84928412328
-
In vitro susceptibility of characterized beta-lactamase-producing gram-negative bacteria isolated in Japan to ceftazidime-, ceftaroline-, and aztreonam-avibactam combinations
-
A.Yoshizumi, Y.Ishii, K.Aoki, et al. In vitro susceptibility of characterized beta-lactamase-producing gram-negative bacteria isolated in Japan to ceftazidime-, ceftaroline-, and aztreonam-avibactam combinations. J Infect Chemother. 2015;21(2):148–151.
-
(2015)
J Infect Chemother
, vol.21
, Issue.2
, pp. 148-151
-
-
Yoshizumi, A.1
Ishii, Y.2
Aoki, K.3
-
61
-
-
79959230230
-
In vitro activity of ceftazidime-NXL104 against 396 strains of beta-lactamase-producing anaerobes
-
D.M.Citron, K.L.Tyrrell, V.Merriam, et al. In vitro activity of ceftazidime-NXL104 against 396 strains of beta-lactamase-producing anaerobes. Antimicrob Agents Chemother. 2011;55(7):3616–3620.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.7
, pp. 3616-3620
-
-
Citron, D.M.1
Tyrrell, K.L.2
Merriam, V.3
-
62
-
-
84940937491
-
Effects of Klebsiella pneumoniae carbapenemase subtypes, extended-spectrum beta-lactamases, and porin mutations on the in vitro activity of ceftazidime-avibactam against carbapenem-resistant K. pneumoniae
-
R.K.Shields, C.J.Clancy, B.Hao, et al. Effects of Klebsiella pneumoniae carbapenemase subtypes, extended-spectrum beta-lactamases, and porin mutations on the in vitro activity of ceftazidime-avibactam against carbapenem-resistant K. pneumoniae. Antimicrob Agents Chemother. 2015;59(9):5793–5797.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.9
, pp. 5793-5797
-
-
Shields, R.K.1
Clancy, C.J.2
Hao, B.3
-
63
-
-
84939545950
-
Activity of ceftazidime/avibactam against isogenic strains of Escherichia coli containing KPC and SHV beta-lactamases with single amino acid substitutions in the Omega-loop
-
M.L.Winkler, K.M.Papp-Wallace, R.A.Bonomo. Activity of ceftazidime/avibactam against isogenic strains of Escherichia coli containing KPC and SHV beta-lactamases with single amino acid substitutions in the Omega-loop. J Antimicrob Chemother. 2015;70(8):2279–2286.
-
(2015)
J Antimicrob Chemother
, vol.70
, Issue.8
, pp. 2279-2286
-
-
Winkler, M.L.1
Papp-Wallace, K.M.2
Bonomo, R.A.3
-
65
-
-
84908638638
-
Efficacy of a Ceftazidime-Avibactam combination in a murine model of Septicemia caused by Enterobacteriaceae species producing ampc or extended-spectrum beta-lactamases
-
P.Levasseur, A.M.Girard, L.Lavallade, et al. Efficacy of a Ceftazidime-Avibactam combination in a murine model of Septicemia caused by Enterobacteriaceae species producing ampc or extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 2014;58(11):6490–6495.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.11
, pp. 6490-6495
-
-
Levasseur, P.1
Girard, A.M.2
Lavallade, L.3
-
66
-
-
84908271938
-
In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates
-
S.H.MacVane, J.L.Crandon, W.W.Nichols, et al. In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates. Antimicrob Agents Chemother. 2014;58(11):6913–6919.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.11
, pp. 6913-6919
-
-
MacVane, S.H.1
Crandon, J.L.2
Nichols, W.W.3
-
68
-
-
78650664486
-
Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae
-
A.Endimiani, K.M.Hujer, A.M.Hujer, et al. Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae. Antimicrob Agents Chemother. 2011;55(1):82–85.• In vivo animal model demonstrating efficacy of CTZ–AVI.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.1
, pp. 82-85
-
-
Endimiani, A.1
Hujer, K.M.2
Hujer, A.M.3
-
69
-
-
84869237392
-
Comparative in vitro and in vivo efficacies of human simulated doses of ceftazidime and ceftazidime-avibactam against Pseudomonas aeruginosa
-
J.L.Crandon, V.J.Schuck, M.A.Banevicius, et al. Comparative in vitro and in vivo efficacies of human simulated doses of ceftazidime and ceftazidime-avibactam against Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2012;56(12):6137–6146.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.12
, pp. 6137-6146
-
-
Crandon, J.L.1
Schuck, V.J.2
Banevicius, M.A.3
-
70
-
-
73649114948
-
Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America
-
J.S.Solomkin, J.E.Mazuski, J.S.Bradley, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children:guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis. 2010;50(2):133–164.
-
(2010)
Clin Infect Dis
, vol.50
, Issue.2
, pp. 133-164
-
-
Solomkin, J.S.1
Mazuski, J.E.2
Bradley, J.S.3
-
71
-
-
84877123198
-
Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial
-
C.Lucasti, I.Popescu, M.K.Ramesh, et al. Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults:results of a randomized, double-blind, Phase II trial. J Antimicrob Chemother. 2013;68(5):1183–1192.•• Phase II clinical trial.
-
(2013)
J Antimicrob Chemother
, vol.68
, Issue.5
, pp. 1183-1192
-
-
Lucasti, C.1
Popescu, I.2
Ramesh, M.K.3
-
72
-
-
84870399321
-
Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study
-
J.A.Vazquez, L.D.Gonzalez Patzan, D.Stricklin, et al. Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults:results of a prospective, investigator-blinded, randomized study. Curr Med Res Opin. 2012;28(12):1921–1931.•• Phase II clinical trial.
-
(2012)
Curr Med Res Opin
, vol.28
, Issue.12
, pp. 1921-1931
-
-
Vazquez, J.A.1
Gonzalez Patzan, L.D.2
Stricklin, D.3
-
73
-
-
84960171720
-
beta-Lactamase characterization of Gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam: clinical efficacies analyzed against subsets of molecularly characterized isolates
-
R.E.Mendes, M.Castanheira, L.Gasink, et al. beta-Lactamase characterization of Gram-negative pathogens recovered from patients enrolled in the phase 2 trials for ceftazidime-avibactam:clinical efficacies analyzed against subsets of molecularly characterized isolates. Antimicrob Agents Chemother. 2015;60(3):1328–1335.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, Issue.3
, pp. 1328-1335
-
-
Mendes, R.E.1
Castanheira, M.2
Gasink, L.3
-
74
-
-
84971578709
-
Efficacy and safety of ceftazidime-avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infection - results from a randomized, controlled, double-blind, phase 3 program
-
J.E.Mazuski, L.Gasink, J.Armstrong, et al. Efficacy and safety of ceftazidime-avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infection - results from a randomized, controlled, double-blind, phase 3 program. Clin Infect Dis. 2016 Mar 8. doi:10.1093/cid/ciw133. [Epub ahead of print]•• First published Phase III clinical trial.
-
(2016)
Clin Infect Dis
-
-
Mazuski, J.E.1
Gasink, L.2
Armstrong, J.3
-
75
-
-
84988361957
-
-
cited, Jan, Available from
-
Positive Phase III Results Demonstrate Efficacy Of Antibiotic Medicine AVYCAZ™ (ceftazidime-avibactam) In Complicated Urinary Tract Infections. Allergen, Inc. [cited 2016 Jan 20]. Available from:http://www.allergan.com/news/news/thomson-reuters/positive-phase-iii-results-demonstrate-efficacy-of
-
(2016)
Allergen, Inc
-
-
-
76
-
-
84988420618
-
Efficacy and safety of ceftazidime-avibactam and best available therapy in the treatment of ceftazidime-resistant infections - results from a Phase III study
-
Y.Carmeli, J.Armstrong, P.J.Laud et al. Efficacy and safety of ceftazidime-avibactam and best available therapy in the treatment of ceftazidime-resistant infections - results from a Phase III study. Poster presentation, ECCMID, LBEV0061b. 2015.
-
(2015)
Poster presentation, ECCMID, LBEV0061b
-
-
Carmeli, Y.1
Armstrong, J.2
Laud, P.J.3
-
77
-
-
84898609105
-
Randomized, placebo-controlled study to assess the impact on QT/QTc interval of supratherapeutic doses of ceftazidime-avibactam or ceftaroline fosamil-avibactam
-
S.Das, J.Armstrong, D.Mathews, et al. Randomized, placebo-controlled study to assess the impact on QT/QTc interval of supratherapeutic doses of ceftazidime-avibactam or ceftaroline fosamil-avibactam. J Clin Pharmacol. 2014;54(3):331–340.
-
(2014)
J Clin Pharmacol
, vol.54
, Issue.3
, pp. 331-340
-
-
Das, S.1
Armstrong, J.2
Mathews, D.3
-
78
-
-
84934993852
-
Ecological effect of ceftazidime/avibactam on the normal human intestinal microbiota
-
M.U.Rashid, S.Rosenborg, G.Panagiotidis, et al. Ecological effect of ceftazidime/avibactam on the normal human intestinal microbiota. Int J Antimicrob Agents. 2015;46(1):60–65.
-
(2015)
Int J Antimicrob Agents
, vol.46
, Issue.1
, pp. 60-65
-
-
Rashid, M.U.1
Rosenborg, S.2
Panagiotidis, G.3
-
79
-
-
79953871631
-
Combating antimicrobial resistance: policy recommendations to save lives
-
Infectious Diseases Society of America, B.Spellberg, M.Blaser, et al. Combating antimicrobial resistance:policy recommendations to save lives. Clin Infect Dis. 2011;52(Suppl 5):S397–428.
-
(2011)
Clin Infect Dis
, vol.52
, Issue.5
, pp. S397-S428
-
-
Spellberg, B.1
Blaser, M.2
-
80
-
-
84942154691
-
Fosfomycin for treatment of prostatitis: new tricks for old dogs
-
M.L.Grayson, N.Macesic, J.Trevillyan, et al. Fosfomycin for treatment of prostatitis:new tricks for old dogs. Clin Infect Dis. 2015;61(7):1141–1143.
-
(2015)
Clin Infect Dis
, vol.61
, Issue.7
, pp. 1141-1143
-
-
Grayson, M.L.1
Macesic, N.2
Trevillyan, J.3
-
81
-
-
84893256345
-
Is fosfomycin a potential treatment alternative for multidrug-resistant gram-negative prostatitis?
-
B.J.Gardiner, A.A.Mahony, A.G.Ellis, et al. Is fosfomycin a potential treatment alternative for multidrug-resistant gram-negative prostatitis? Clin Infect Dis. 2014;58(4):e101–105.
-
(2014)
Clin Infect Dis
, vol.58
, Issue.4
, pp. e101-e105
-
-
Gardiner, B.J.1
Mahony, A.A.2
Ellis, A.G.3
-
82
-
-
84884764949
-
Kinetics of avibactam inhibition against Class A, C, and D beta-lactamases
-
D.E.Ehmann, H.Jahic, P.L.Ross, et al. Kinetics of avibactam inhibition against Class A, C, and D beta-lactamases. J Biol Chem. 2013;288(39):27960–27971.
-
(2013)
J Biol Chem
, vol.288
, Issue.39
, pp. 27960-27971
-
-
Ehmann, D.E.1
Jahic, H.2
Ross, P.L.3
-
83
-
-
84960156283
-
The role of the outer membrane and porins in the susceptibility of beta-lactamase-producing Enterobacteriaceae to ceftazidime-avibactam
-
J.M.Pages, S.Peslier, T.A.Keating, et al. The role of the outer membrane and porins in the susceptibility of beta-lactamase-producing Enterobacteriaceae to ceftazidime-avibactam. Antimicrob Agents Chemother. 2015;60(3):1349–1359.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, Issue.3
, pp. 1349-1359
-
-
Pages, J.M.1
Peslier, S.2
Keating, T.A.3
-
84
-
-
84861873121
-
NXL104 irreversibly inhibits the beta-lactamase from Mycobacterium tuberculosis
-
H.Xu, S.Hazra, J.S.Blanchard. NXL104 irreversibly inhibits the beta-lactamase from Mycobacterium tuberculosis. Biochemistry. 2012;51(22):4551–4557.
-
(2012)
Biochemistry
, vol.51
, Issue.22
, pp. 4551-4557
-
-
Xu, H.1
Hazra, S.2
Blanchard, J.S.3
-
85
-
-
84957878384
-
Pharmacodynamics of Ceftazidime and Avibactam in neutropenic mice with thigh- or lung-infection
-
J.Berkhout, M.J.Melchers, A.C.Van Mil, et al. Pharmacodynamics of Ceftazidime and Avibactam in neutropenic mice with thigh- or lung-infection. Antimicrob Agents Chemother. 2015;60(1):368–375.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, Issue.1
, pp. 368-375
-
-
Berkhout, J.1
Melchers, M.J.2
Van Mil, A.C.3
-
86
-
-
79952120627
-
Activity of a novel combination against multidrug-resistant nonfermenters: ceftazidime plus NXL104
-
D.Curcio. Activity of a novel combination against multidrug-resistant nonfermenters:ceftazidime plus NXL104. Expert Rev Anti Infect Ther. 2011;9(2):173–176.
-
(2011)
Expert Rev Anti Infect Ther
, vol.9
, Issue.2
, pp. 173-176
-
-
Curcio, D.1
-
87
-
-
84928202650
-
Activity of avibactam against Enterobacter cloacae producing an extended-spectrum class C beta-lactamase enzyme
-
S.D.Lahiri, R.A.Giacobbe, M.R.Johnstone, et al. Activity of avibactam against Enterobacter cloacae producing an extended-spectrum class C beta-lactamase enzyme. J Antimicrob Chemother. 2014;69(11):2942–2946.
-
(2014)
J Antimicrob Chemother
, vol.69
, Issue.11
, pp. 2942-2946
-
-
Lahiri, S.D.1
Giacobbe, R.A.2
Johnstone, M.R.3
-
88
-
-
84923240983
-
In vitro susceptibility of characterized beta-lactamase-producing strains tested with avibactam combinations
-
H.Li, M.Estabrook, G.A.Jacoby, et al. In vitro susceptibility of characterized beta-lactamase-producing strains tested with avibactam combinations. Antimicrob Agents Chemother. 2015;59(3):1789–1793.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.3
, pp. 1789-1793
-
-
Li, H.1
Estabrook, M.2
Jacoby, G.A.3
-
89
-
-
54549112247
-
NXL104 combinations versus Enterobacteriaceae with CTX-M extended-spectrum beta-lactamases and carbapenemases
-
D.M.Livermore, S.Mushtaq, M.Warner, et al. NXL104 combinations versus Enterobacteriaceae with CTX-M extended-spectrum beta-lactamases and carbapenemases. J Antimicrob Chemother. 2008;62(5):1053–1056.
-
(2008)
J Antimicrob Chemother
, vol.62
, Issue.5
, pp. 1053-1056
-
-
Livermore, D.M.1
Mushtaq, S.2
Warner, M.3
-
90
-
-
84905406150
-
Reclaiming the efficacy of beta-lactam-beta-lactamase inhibitor combinations: avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime
-
K.M.Papp-Wallace, M.L.Winkler, J.A.Gatta, et al. Reclaiming the efficacy of beta-lactam-beta-lactamase inhibitor combinations:avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime. Antimicrob Agents Chemother. 2014;58(8):4290–4297.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.8
, pp. 4290-4297
-
-
Papp-Wallace, K.M.1
Winkler, M.L.2
Gatta, J.A.3
-
91
-
-
84941621511
-
Ceftazidime-avibactam in urinary tract infections due to carbapenemase-producing Klebsiella in kidney transplantation
-
F.Caravaca-Fontan, S.Jimenez-Alvaro, R.Marcen-Letosa, et al. Ceftazidime-avibactam in urinary tract infections due to carbapenemase-producing Klebsiella in kidney transplantation. Nefrologia. 2015;35(4):412–413.
-
(2015)
Nefrologia
, vol.35
, Issue.4
, pp. 412-413
-
-
Caravaca-Fontan, F.1
Jimenez-Alvaro, S.2
Marcen-Letosa, R.3
-
92
-
-
84942903035
-
First report of ceftazidime-avibactam resistance in a KPC-3 expressing Klebsiella pneumoniae
-
R.M.Humphries, S.Yang, P.Hemarajata, et al. First report of ceftazidime-avibactam resistance in a KPC-3 expressing Klebsiella pneumoniae. Antimicrob Agents Chemother. 2015;59(10):6605–6607.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.10
, pp. 6605-6607
-
-
Humphries, R.M.1
Yang, S.2
Hemarajata, P.3
-
93
-
-
84930510339
-
Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC
-
S.D.Lahiri, G.K.Walkup, J.D.Whiteaker, et al. Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC. J Antimicrob Chemother. 2015;70(6):1650–1658.
-
(2015)
J Antimicrob Chemother
, vol.70
, Issue.6
, pp. 1650-1658
-
-
Lahiri, S.D.1
Walkup, G.K.2
Whiteaker, J.D.3
-
94
-
-
84940901399
-
In vitro selection of ceftazidime-avibactam resistance in Enterobacteriaceae with KPC-3 Carbapenemase
-
D.M.Livermore, M.Warner, D.Jamrozy, et al. In vitro selection of ceftazidime-avibactam resistance in Enterobacteriaceae with KPC-3 Carbapenemase. Antimicrob Agents Chemother. 2015;59(9):5324–5330.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.9
, pp. 5324-5330
-
-
Livermore, D.M.1
Warner, M.2
Jamrozy, D.3
-
95
-
-
84931291736
-
Variants of beta-lactamase KPC-2 that are resistant to inhibition by avibactam
-
K.M.Papp-Wallace, M.L.Winkler, M.A.Taracila, et al. Variants of beta-lactamase KPC-2 that are resistant to inhibition by avibactam. Antimicrob Agents Chemother. 2015;59(7):3710–3717.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.7
, pp. 3710-3717
-
-
Papp-Wallace, K.M.1
Winkler, M.L.2
Taracila, M.A.3
-
96
-
-
84959570300
-
Co-production of KPC-18 and VIM-1 Carbapenemases by Enterobacter cloacae: implications for newer beta-lactam-beta-lactamase inhibitor combinations
-
G.K.Thomson, J.W.Snyder, C.L.McElheny, et al. Co-production of KPC-18 and VIM-1 Carbapenemases by Enterobacter cloacae:implications for newer beta-lactam-beta-lactamase inhibitor combinations. J Clin Microbiol. 2015;54(3):791–794.
-
(2015)
J Clin Microbiol
, vol.54
, Issue.3
, pp. 791-794
-
-
Thomson, G.K.1
Snyder, J.W.2
McElheny, C.L.3
-
97
-
-
84921797970
-
Unexpected challenges in treating multidrug-resistant gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa
-
M.L.Winkler, K.M.Papp-Wallace, A.M.Hujer, et al. Unexpected challenges in treating multidrug-resistant gram-negative bacteria:resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2015;59(2):1020–1029.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.2
, pp. 1020-1029
-
-
Winkler, M.L.1
Papp-Wallace, K.M.2
Hujer, A.M.3
-
98
-
-
77951060664
-
Current challenges in antimicrobial chemotherapy: focus on ss-lactamase inhibition
-
C.Bebrone, P.Lassaux, L.Vercheval, et al. Current challenges in antimicrobial chemotherapy:focus on ss-lactamase inhibition. Drugs. 2010;70(6):651–679.
-
(2010)
Drugs
, vol.70
, Issue.6
, pp. 651-679
-
-
Bebrone, C.1
Lassaux, P.2
Vercheval, L.3
-
99
-
-
77956666195
-
New beta-lactam antibiotics and beta-lactamase inhibitors
-
K.Bush, M.J.Macielag. New beta-lactam antibiotics and beta-lactamase inhibitors. Expert Opin Ther Pat. 2010;20(10):1277–1293.
-
(2010)
Expert Opin Ther Pat
, vol.20
, Issue.10
, pp. 1277-1293
-
-
Bush, K.1
Macielag, M.J.2
-
100
-
-
84934286719
-
A beta-lactamase inhibitor revival provides new hope for old antibiotics
-
K.Garber. A beta-lactamase inhibitor revival provides new hope for old antibiotics. Nat Rev Drug Discov. 2015;14(7):445–447.
-
(2015)
Nat Rev Drug Discov
, vol.14
, Issue.7
, pp. 445-447
-
-
Garber, K.1
-
101
-
-
84946497998
-
Ceftazidime-avibactam for the treatment of complicated urinary tract infections and complicated intra-abdominal infections
-
Y.Mawal, I.A.Critchley, T.A.Riccobene, et al. Ceftazidime-avibactam for the treatment of complicated urinary tract infections and complicated intra-abdominal infections. Expert Rev Clin Pharmacol. 2015;8(6):691–707.
-
(2015)
Expert Rev Clin Pharmacol
, vol.8
, Issue.6
, pp. 691-707
-
-
Mawal, Y.1
Critchley, I.A.2
Riccobene, T.A.3
-
102
-
-
84939799864
-
Focus on ceftazidime-avibactam for optimizing outcomes in complicated intra-abdominal and urinary tract infections
-
D.P.Nicolau. Focus on ceftazidime-avibactam for optimizing outcomes in complicated intra-abdominal and urinary tract infections. Expert Opin Investig Drugs. 2015;24(9):1261–1273.
-
(2015)
Expert Opin Investig Drugs
, vol.24
, Issue.9
, pp. 1261-1273
-
-
Nicolau, D.P.1
-
103
-
-
84975871919
-
Ceftazidime with beta-lactamase inhibitor approved for complicated infections
-
C.A.Thompson. Ceftazidime with beta-lactamase inhibitor approved for complicated infections. Am J Health Syst Pharm. 2015;72(7):511.
-
(2015)
Am J Health Syst Pharm
, vol.72
, Issue.7
, pp. 511
-
-
Thompson, C.A.1
-
104
-
-
84939486487
-
The beta-lactams strike sack: ceftazidime-avibactam
-
E.J.Zasowski, J.M.Rybak, M.J.Rybak. The beta-lactams strike sack:ceftazidime-avibactam. Pharmacotherapy. 2015;35(8):755–770.
-
(2015)
Pharmacotherapy
, vol.35
, Issue.8
, pp. 755-770
-
-
Zasowski, E.J.1
Rybak, J.M.2
Rybak, M.J.3
|