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Volumn 24, Issue 9, 2015, Pages 1261-1273

Focus on ceftazidime-avibactam for optimizing outcomes in complicated intra-abdominal and urinary tract infections

Author keywords

avibactam; ceftazidime; intra abdominal infections; urinary tract infections; lactamases

Indexed keywords

2 HYDROXY 3 (2 THIENYLACETAMIDO) 1,5,2 DIOXABOREPANE 7 ACETIC ACID; ANTIBIOTIC AGENT; AVIBACTAM; AVIBACTAM PLUS CEFTAZIDIME; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; CARBAPENEM; CARBAPENEMASE; CEFEPIME; CEFTAZIDIME; CEFTOLOZANE PLUS TAZOBACTAM; CEPHALOSPORIN; CILASTATIN PLUS IMIPENEM; CIPROFLOXACIN; CREATININE; EXTENDED SPECTRUM BETA LACTAMASE; LEVOFLOXACIN; LINEZOLID; LIVER ENZYME; MEROPENEM; METRONIDAZOLE; NEW DRUG; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RELEBACTAM; TOBRAMYCIN; UNINDEXED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; AVIBACTAM, CEFTAZIDIME DRUG COMBINATION; AZABICYCLO DERIVATIVE;

EID: 84939799864     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2015.1062873     Document Type: Review
Times cited : (8)

References (69)
  • 2
    • 77149165713 scopus 로고    scopus 로고
    • Updated functional classification of b-lactamases
    • Bush K, Jacoby GA. Updated functional classification of b-lactamases. Antimicrob Agents Chemother 2010;54:969-76
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 969-976
    • Bush, K.1    Jacoby, G.A.2
  • 3
    • 0029071785 scopus 로고
    • A functional classification scheme for b-lactamases and its correlation with molecular structure
    • Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for b-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother 1995;39:1211-33
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 1211-1233
    • Bush, K.1    Jacoby, G.A.2    Medeiros, A.A.3
  • 4
    • 27144490073 scopus 로고    scopus 로고
    • Extended-spectrum b-lactamases: A clinical update
    • Paterson DL, Bonomo RA. Extended-spectrum b-lactamases: a clinical update. Clin Microbiol Rev 2005;18:657-86
    • (2005) Clin Microbiol Rev , vol.18 , pp. 657-686
    • Paterson, D.L.1    Bonomo, R.A.2
  • 5
    • 71549169890 scopus 로고    scopus 로고
    • Extended-spectrum b-lactamase-producing organisms
    • Falagas ME, Karageorgopoulos DE. Extended-spectrum b-lactamase-producing organisms. J Hosp Infect 2009;73:345-54
    • (2009) J Hosp Infect , vol.73 , pp. 345-354
    • Falagas, M.E.1    Karageorgopoulos, D.E.2
  • 6
  • 7
    • 84908030429 scopus 로고    scopus 로고
    • Carbapenemases in enterobacteriaceae: The magnitude of a worldwide concern
    • Rolain JM, Cornaglia G. Carbapenemases in Enterobacteriaceae: the magnitude of a worldwide concern. Clin Microbiol Infect 2014;20:819-20
    • (2014) Clin Microbiol Infect , vol.20 , pp. 819-820
    • Rolain, J.M.1    Cornaglia, G.2
  • 8
    • 84877798581 scopus 로고    scopus 로고
    • Carbapenem-resistant enterobacteriaceae: A menace to our most vulnerable patients
    • Perez F, van Duin D. Carbapenem-resistant Enterobacteriaceae: A menace to our most vulnerable patients. Cleve Clin J Med 2013;80:224-33
    • (2013) Cleve Clin J Med , vol.80 , pp. 224-233
    • Perez, F.1    Van Duin, D.2
  • 9
    • 84899511797 scopus 로고    scopus 로고
    • Worldwide dissemination of the ndmtype carbapenemases in gram-negative bacteria
    • Dortet L, Poirel L, Nordmann P. Worldwide dissemination of the NDMtype carbapenemases in Gram-negative bacteria. BioMed Res Int 2014;2014:249856
    • (2014) BioMed Res Int , vol.2014 , pp. 249856
    • Dortet, L.1    Poirel, L.2    Nordmann, P.3
  • 10
    • 69049110965 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-A phenomenon of bacterial resistance
    • Strateva T, Yordanov D. Pseudomonas aeruginosa-A phenomenon of bacterial resistance. J Med Microbiol 2009;58:1133-48
    • (2009) J Med Microbiol , vol.58 , pp. 1133-1148
    • Strateva, T.1    Yordanov, D.2
  • 11
    • 42549108748 scopus 로고    scopus 로고
    • Acinetobacter baumannii: Epidemiology, antimicrobial resistance, and treatment options
    • Maragakis LL, Perl TM. Acinetobacter baumannii: Epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis 2008;46:1254-63
    • (2008) Clin Infect Dis , vol.46 , pp. 1254-1263
    • Maragakis, L.L.1    Perl, T.M.2
  • 12
    • 73649114948 scopus 로고    scopus 로고
    • Diagnosis and management of complicated intra-Abdominal infection in adults and children: Guidelines by the surgical infection society and the infectious diseases society of america
    • Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-Abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis 2010;50:133-64
    • (2010) Clin Infect Dis , vol.50 , pp. 133-164
    • Solomkin, J.S.1    Mazuski, J.E.2    Bradley, J.S.3
  • 13
    • 84865864098 scopus 로고    scopus 로고
    • Changing bacteriology of abdominal and surgical sepsis
    • Chen YH, Hsueh PR. Changing bacteriology of abdominal and surgical sepsis. Curr Opin Infect Dis 2012;25:590-5
    • (2012) Curr Opin Infect Dis , vol.25 , pp. 590-595
    • Chen, Y.H.1    Hsueh, P.R.2
  • 14
    • 84887157965 scopus 로고    scopus 로고
    • A review of ten years of the study for monitoring antimicrobial resistance trends (smart) from 2002 to 2011
    • Morrissey I, Hackel M, Badal R, et al. A review of ten years of the Study for Monitoring Antimicrobial Resistance Trends (SMART) from 2002 to 2011. Pharmaceuticals 2013;6:1335-46
    • (2013) Pharmaceuticals , vol.6 , pp. 1335-1346
    • Morrissey, I.1    Hackel, M.2    Badal, R.3
  • 15
    • 84902120635 scopus 로고    scopus 로고
    • In vitro susceptibility and distribution of b-lactamases in enterobacteriaceae causing intra-Abdominal infections in North America 2010-2011
    • Hoban DJ, Badal R, Bouchillon S, et al. In vitro susceptibility and distribution of b-lactamases in Enterobacteriaceae causing intra-Abdominal infections in North America 2010-2011. Diagn Microbiol Infect Dis 2014;79:367-72
    • (2014) Diagn Microbiol Infect Dis , vol.79 , pp. 367-372
    • Hoban, D.J.1    Badal, R.2    Bouchillon, S.3
  • 16
    • 85027920728 scopus 로고    scopus 로고
    • Trends in susceptibility of selected gram-negative bacilli isolated from intraabdominal infections in North America: Smart 2005-2010
    • Babinchak T, Badal R, Hoban D, et al. Trends in susceptibility of selected gram-negative bacilli isolated from intraabdominal infections in North America: SMART 2005-2010. Diagn Microbiol Infect Dis 2013;76:379-81
    • (2013) Diagn Microbiol Infect Dis , vol.76 , pp. 379-381
    • Babinchak, T.1    Badal, R.2    Hoban, D.3
  • 17
    • 84886924257 scopus 로고    scopus 로고
    • Trends in antibiotic resistance over time among pathogens from canadian hospitals: Results of the canward study 2007-11
    • Lagace-Wiens PRS, Adam HJ, Low DE, et al. Trends in antibiotic resistance over time among pathogens from Canadian hospitals: results of the CANWARD study 2007-11. J Antimicrob Chemother 2013;68(Suppl 1):i23-9
    • (2013) J Antimicrob Chemother , vol.68 , pp. i23-i29
    • Lagace-Wiens, P.R.S.1    Adam, H.J.2    Low, D.E.3
  • 18
    • 84903893512 scopus 로고    scopus 로고
    • Ceftazidime/avibactam activity tested against gram-negative bacteria isolated from bloodstream, pneumonia, intraabdominal and urinary tract infections in us medical centres (2012)
    • Flamm RK, Farrell DJ, Sader HS, et al. Ceftazidime/avibactam activity tested against Gram-negative bacteria isolated from bloodstream, pneumonia, intraabdominal and urinary tract infections in US medical centres (2012). J Antimicrob Chemother 2014;69:1589-98
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1589-1598
    • Flamm, R.K.1    Farrell, D.J.2    Sader, H.S.3
  • 19
    • 0029833749 scopus 로고    scopus 로고
    • Emergence of antibiotic-resistance bacteria in cases of peritonitis after intraabdominal surgery affects the efficacy of empirical antimicrobial therapy
    • Montravers P, Gauzit R, Muller C, et al. Emergence of antibiotic-resistance bacteria in cases of peritonitis after intraabdominal surgery affects the efficacy of empirical antimicrobial therapy. Clin Infect Dis 1996;23:486-94
    • (1996) Clin Infect Dis , vol.23 , pp. 486-494
    • Montravers, P.1    Gauzit, R.2    Muller, C.3
  • 20
    • 0025949142 scopus 로고
    • Antibiotic treatment for surgical peritonitis
    • Mosdell DM, Morris DM, Voltura A, et al. Antibiotic treatment for surgical peritonitis. Ann Surg 1991;214:543-9
    • (1991) Ann Surg , vol.214 , pp. 543-549
    • Mosdell, D.M.1    Morris, D.M.2    Voltura, A.3
  • 21
    • 84876445247 scopus 로고    scopus 로고
    • Diagnosis and management of simple and complicated urinary tract infections (utis)
    • Mazzulli T. Diagnosis and management of simple and complicated urinary tract infections (UTIs). Can J Urol 2012;19(Suppl 1):42-8
    • (2012) Can J Urol , vol.19 , pp. 42-48
    • Mazzulli, T.1
  • 22
    • 76749145037 scopus 로고    scopus 로고
    • Diagnosis prevention and treatment of catheter-Associated urinary tract infection in adults: 2009 international clinical practice guidelines from the infectious diseases society of america
    • Hooton TM, Bradley SF, Cardenas DD, et al. Diagnosis, prevention, and treatment of catheter-Associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis 2010;50:625-63
    • (2010) Clin Infect Dis , vol.50 , pp. 625-663
    • Hooton, T.M.1    Bradley, S.F.2    Cardenas, D.D.3
  • 23
    • 84870946642 scopus 로고    scopus 로고
    • Antimicrobial-resistant pathogens associated with healthcare-Associated infections: Summary of data reported to the national healthcare safety network at the centers for disease control and prevention 2009-2010
    • Sievert DM, Ricks P, Edwards JR, et al. Antimicrobial-resistant pathogens associated with healthcare-Associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010. Infect Control Hosp Epidemiol 2013;34:1-14
    • (2013) Infect Control Hosp Epidemiol , vol.34 , pp. 1-14
    • Sievert, D.M.1    Ricks, P.2    Edwards, J.R.3
  • 24
    • 84900306358 scopus 로고    scopus 로고
    • Frequency of occurrence and antimicrobial susceptibility of gramnegative bacteremia isolates in patients with urinary tract infection: Results from United States and european hospitals 2009-2011)
    • Sader HS, Flamm RK, Jones RN. Frequency of occurrence and antimicrobial susceptibility of Gramnegative bacteremia isolates in patients with urinary tract infection: results from United States and European hospitals (2009-2011). J Chemother 2014;26:133-8
    • (2014) J Chemother , vol.26 , pp. 133-138
    • Sader, H.S.1    Flamm, R.K.2    Jones, R.N.3
  • 25
    • 84866469331 scopus 로고    scopus 로고
    • Fluoroquinolone resistance among gramnegative urinary tract pathogens: Global smart program results 2009-2010
    • Bouchillon S, Hoban DJ, Badal R, et al. Fluoroquinolone resistance among Gramnegative urinary tract pathogens: global SMART program results, 2009-2010. Open Microbiol J 2012;6:74-8
    • (2012) Open Microbiol J , vol.6 , pp. 74-78
    • Bouchillon, S.1    Hoban, D.J.2    Badal, R.3
  • 26
    • 84903382735 scopus 로고    scopus 로고
    • Influence of inadequate antimicrobial therapy on prognosis in elderly patients with severe urinary tract infections
    • Esparcia A, Artero A, Eiros JM, et al. Influence of inadequate antimicrobial therapy on prognosis in elderly patients with severe urinary tract infections. Eur J Intern Med 2014;25:523-7
    • (2014) Eur J Intern Med , vol.25 , pp. 523-527
    • Esparcia, A.1    Artero, A.2    Eiros, J.M.3
  • 27
    • 84898602351 scopus 로고    scopus 로고
    • Impact of extended-spectrum b-lactamase-producing organisms on clinical and economic outcomes in patients with urinary tract infections
    • MacVane SH, Tuttle LO, Nicolau DP. Impact of extended-spectrum b-lactamase-producing organisms on clinical and economic outcomes in patients with urinary tract infections. J Hosp Med 2014;9:232-8
    • (2014) J Hosp Med , vol.9 , pp. 232-238
    • MacVane, S.H.1    Tuttle, L.O.2    Nicolau, D.P.3
  • 28
    • 84943585403 scopus 로고    scopus 로고
    • Demography and burden of care associated with patients readmitted for urinary tract infection
    • [Epub ahead of print]
    • MacVane SH, Tuttle LO, Nicolau DP. Demography and burden of care associated with patients readmitted for urinary tract infection. J Microbiol Immunol Infect 2014. [Epub ahead of print]
    • (2014) J Microbiol Immunol Infect
    • MacVane, S.H.1    Tuttle, L.O.2    Nicolau, D.P.3
  • 29
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: No eskape! An update from the infectious diseases society of america
    • Boucher HW, Talbot GH, Bradley JS, et al. Bad bugs, no drugs: No ESKAPE! an update from the infectious diseases society of america. Clin Infect Dis 2009;48:1-12
    • (2009) Clin Infect Dis , vol.48 , pp. 1-12
    • Boucher, H.W.1    Talbot, G.H.2    Bradley, J.S.3
  • 30
    • 84865393141 scopus 로고    scopus 로고
    • 2012 and beyond: Potential for the start of a second preantibiotic era?
    • Appelbaum PC. 2012 and beyond: potential for the start of a second preantibiotic era? J Antimicrob Chemother 2012;67:2062-8
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2062-2068
    • Appelbaum, P.C.1
  • 31
    • 84888579845 scopus 로고    scopus 로고
    • Ceftolozane/tazobactam: A novel antipseudomonal cephalosporin and b-lactamase-inhibitor combination
    • Hong M-C, Hsu DI, Bounthavong M. Ceftolozane/tazobactam: a novel antipseudomonal cephalosporin and b-lactamase-inhibitor combination. Infect Drug Res 2013;6:215-23
    • (2013) Infect Drug Res , vol.6 , pp. 215-223
    • Hong, M.-C.1    Hsu, D.I.2    Bounthavong, M.3
  • 32
    • 84888787952 scopus 로고    scopus 로고
    • Activity of mk-7655 combined with imipenem against enterobacteriaceae and pseudomonas aeruginosa
    • Livermore DM, Warner M, Mushtaq S. Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa. J Antimicrob Chemother 2013;68:2286-90
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2286-2290
    • Livermore, D.M.1    Warner, M.2    Mushtaq, S.3
  • 33
    • 84880714408 scopus 로고    scopus 로고
    • Activity of biapenem (rpx2003) combined with the boronate b-lactamase inhibitor rpx7009 against carbapenems-resistant enterobacteriaceae
    • Livermore DM, Mushtaq S. Activity of biapenem (RPX2003) combined with the boronate b-lactamase inhibitor RPX7009 against carbapenems-resistant Enterobacteriaceae. J Antimicrob Chemother 2013;68:1825-31
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1825-1831
    • Livermore, D.M.1    Mushtaq, S.2
  • 34
    • 78650636489 scopus 로고    scopus 로고
    • Activities of nxl104 combinations with ceftazidime and aztreonam against carbapenemase-producing enterobacteriaceae
    • Livermore DM, Mushtaq S, Warner M, et al. Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae. Antimicrob Agents Chemother 2011;55:390-4
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 390-394
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3
  • 35
    • 84897997775 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of gramnegative organisms isolates from patients hospitalized with pneumonia in us and european hospitals: Results from the sentry antimicrobial surveillance program 2009-2012
    • Sader HS, Farrell DJ, Flamm RK, et al. Antimicrobial susceptibility of Gramnegative organisms isolates from patients hospitalized with pneumonia in US and European hospitals: results from the SENTRY Antimicrobial Surveillance Program, 2009-2012. Int J Antimicrob Agents 2014;43:328-34
    • (2014) Int J Antimicrob Agents , vol.43 , pp. 328-334
    • Sader, H.S.1    Farrell, D.J.2    Flamm, R.K.3
  • 36
    • 84863905057 scopus 로고    scopus 로고
    • Avibactam is a covalent, reversible, non-b-lactam b-lactamase inhibitor
    • Ehmann DE, Jahić H, Ross PL, et al. Avibactam is a covalent, reversible, non-b-lactam b-lactamase inhibitor. Proc Natl Acad Sci USA 2012;109:11663-8
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 11663-11668
    • Ehmann, D.E.1    Jahić, H.2    Ross, P.L.3
  • 37
    • 84884764949 scopus 로고    scopus 로고
    • Kinetics of avibactam inhibition against class a, c, and d b-lactamases
    • Ehmann DE, Jahić H, Ross PL, et al. Kinetics of avibactam inhibition against Class A, C, and D b-lactamases. J Biol Chem 2013;288:27960-71
    • (2013) J Biol Chem , vol.288 , pp. 27960-27971
    • Ehmann, D.E.1    Jahić, H.2    Ross, P.L.3
  • 38
    • 79955537450 scopus 로고    scopus 로고
    • Activity of nxl 104 in combination with b-lactams against genetically characterized Escherichia coli and klebsiella pneumoniae isolates producing class a extended-spectrum b-lactamases and class c b-lactamases
    • Lagace-Wiens PRS, Tailor F, Simner P, et al. Activity of NXL 104 in combination with b-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing Class A extended-spectrum b-lactamases and Class C b-lactamases. Antimicrob Agents Chemother 2011;55:2434-7
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2434-2437
    • Lagace-Wiens, P.R.S.1    Tailor, F.2    Simner, P.3
  • 39
    • 84857173233 scopus 로고    scopus 로고
    • In vitro antibacterial activity of the ceftazidime-Avibactam (nxl104) combination against pseudomonas aeruginosa clinical isolates
    • Levasseur P, Girard A-M, Claudon M, et al. In vitro antibacterial activity of the ceftazidime-Avibactam (NXL104) combination against Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother 2012;56:1606-8
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1606-1608
    • Levasseur, P.1    Girard, A.-M.2    Claudon, M.3
  • 40
    • 84921784867 scopus 로고    scopus 로고
    • In vitro activity of ceftazidimeavibactam combination in in vitro checkerboard assays
    • Berkhout J, Melchers MJ, van Mil AC, et al. In vitro activity of ceftazidimeavibactam combination in in vitro checkerboard assays. Antimicrob Agents Chemother 2015;59:1138-44
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 1138-1144
    • Berkhout, J.1    Melchers, M.J.2    Van Mil, A.C.3
  • 41
    • 84896833758 scopus 로고    scopus 로고
    • Antimicrobial activity of ceftazidime-Avibactam against gramnegative organisms collected from us medical centers in 2012
    • Sader HS, Castanheira M, Flamm RK, et al. Antimicrobial activity of ceftazidime-Avibactam against gramnegative organisms collected from US medical centers in 2012. Antimicrob Agents Chemother 2014;58:1684-92
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 1684-1692
    • Sader, H.S.1    Castanheira, M.2    Flamm, R.K.3
  • 42
    • 84896832898 scopus 로고    scopus 로고
    • In vitro activities of ceftazidime-Avibactam and aztreonam-Avibactam against 372 gram-negative bacilli collected in 2011 and 2012 from 11 teaching hospitals in China
    • Wang X, Zhang F, Zhao C, et al. In vitro activities of ceftazidime-Avibactam and aztreonam-Avibactam against 372 gram-negative bacilli collected in 2011 and 2012 from 11 teaching hospitals in China. Antimicrob Agents Chemother 2014;58:1774-8
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 1774-1778
    • Wang, X.1    Zhang, F.2    Zhao, C.3
  • 43
    • 82955187694 scopus 로고    scopus 로고
    • In vitro activity of avibactam (nxl 104) in combination with b-lactams against gram-negative bacteria, including oxa-48 b-lactamase-producing klebsiella pneumoniae
    • Aktas Z, Kayacan C, Oncul O. In vitro activity of avibactam (NXL 104) in combination with b-lactams against gram-negative bacteria, including OXA-48 b-lactamase-producing Klebsiella pneumoniae. Int J Antimicrob Agents 2012;39:86-9
    • (2012) Int J Antimicrob Agents , vol.39 , pp. 86-89
    • Aktas, Z.1    Kayacan, C.2    Oncul, O.3
  • 44
    • 84920099992 scopus 로고    scopus 로고
    • Avibactam reverts the ceftazidime mic90 of european gram-negative bacterial clinical isolates to the epidemiological cut-off value
    • Flamm RK, Stone GG, Sader HS, et al. Avibactam reverts the ceftazidime MIC90 of European gram-negative bacterial clinical isolates to the epidemiological cut-off value. J Chemother 2014;26:333-8
    • (2014) J Chemother , vol.26 , pp. 333-338
    • Flamm, R.K.1    Stone, G.G.2    Sader, H.S.3
  • 45
    • 84906074469 scopus 로고    scopus 로고
    • Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-Avibactam against b-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa
    • Keepers TR, Gomez M, Celeri C, et al. Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-Avibactam against b-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother 2014;58:5297-305
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 5297-5305
    • Keepers, T.R.1    Gomez, M.2    Celeri, C.3
  • 46
    • 0347694556 scopus 로고    scopus 로고
    • Basic pharmacodynamics of antibacterials with clinical applications to the use of b-lactams, glycopeptides, and linezolid
    • Craig WA. Basic pharmacodynamics of antibacterials with clinical applications to the use of b-lactams, glycopeptides, and linezolid. Infect Dis Clin N Am 2003;17:479-501
    • (2003) Infect Dis Clin N Am , vol.17 , pp. 479-501
    • Craig, W.A.1
  • 47
    • 84875273480 scopus 로고    scopus 로고
    • Optimal exposures of ceftazidime predict the probability of microbiological and clinical outcome in the treatment of nosocomial pneumonia
    • Muller AE, Punt N, Mouton JW. Optimal exposures of ceftazidime predict the probability of microbiological and clinical outcome in the treatment of nosocomial pneumonia. J Antimicrob Chemother 2013;68:900-6
    • (2013) J Antimicrob Chemother , vol.68 , pp. 900-906
    • Muller, A.E.1    Punt, N.2    Mouton, J.W.3
  • 48
    • 84896809646 scopus 로고    scopus 로고
    • Clinical pharmacodynamics of antipseudomonal cephalosporins in patients with ventilator-Associated pneumonia
    • MacVane SH, Kuti JL, Nicolau DP. Clinical pharmacodynamics of antipseudomonal cephalosporins in patients with ventilator-Associated pneumonia. Antimicrob Agents Chemother 2014;58:1359-64
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 1359-1364
    • MacVane, S.H.1    Kuti, J.L.2    Nicolau, D.P.3
  • 49
    • 84901260013 scopus 로고    scopus 로고
    • Activities of ceftazidime and avibactam against b-lactamase-producing enterobacteriaceae in a hollow-fiber pharmacodynamic model
    • Coleman K, Levasseur P, Girard AM, et al. Activities of ceftazidime and avibactam against b-lactamase-producing Enterobacteriaceae in a hollow-fiber pharmacodynamic model. Antimicrob Agents Chemother 2014;58:3366-72
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 3366-3372
    • Coleman, K.1    Levasseur, P.2    Girard, A.M.3
  • 50
    • 84939841898 scopus 로고    scopus 로고
    • A threshold concentration of avibactam (avi) during the pharmacokinetic decline phase below which b-lactamase inhibition in enterobacteriaceae becomes ineffective. [abstract a-1760]
    • 9-12 September; San Francisco, California, USA
    • Nichols W, Levasseur P, Li J, et al. A threshold concentration of avibactam (AVI) during the pharmacokinetic decline phase, below which b-lactamase inhibition in Enterobacteriaceae becomes ineffective. [abstract A-1760]. Paper presented at 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy9-12 September, 2012; San Francisco, California, USA
    • (2012) Paper Presented at 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Nichols, W.1    Levasseur, P.2    Li, J.3
  • 53
    • 84877070063 scopus 로고    scopus 로고
    • Population pharmacokinetic modeling of ceftazidime (caz) and avibactam (avi) in healthy volunteers and patients with complicated intra-Abdominal infection (ciais). [abstract a-634]
    • 9-12 September; San Francisco, California, USA
    • Li J, Knebel W, Riggs M, et al. Population pharmacokinetic modeling of ceftazidime (CAZ) and avibactam (AVI) in healthy volunteers and patients with complicated intra-Abdominal infection (cIAIs). [abstract A-634]. Paper presented at 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy; 9-12 September, 2012; San Francisco, California, USA
    • (2012) Paper Presented at 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy;
    • Li, J.1    Knebel, W.2    Riggs, M.3
  • 54
    • 84973425791 scopus 로고    scopus 로고
    • Pharmacokinetics of avibactam (avi) and ceftazidime (caz) following separate or combined administration in healthy volunteers. [abstract a-1019]
    • 10-13 September; Denver, Colorado, USA
    • Edeki T, Armstrong J, Li J. Pharmacokinetics of avibactam (AVI) and ceftazidime (CAZ) following separate or combined administration in healthy volunteers. [abstract A-1019]. Paper presented at 53rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; 10-13 September, 2013; Denver, Colorado, USA
    • (2013) Paper Presented at 53rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy;
    • Edeki, T.1    Armstrong, J.2    Li, J.3
  • 55
    • 84995439176 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of nxl 104 in normal subjects and patients with varying degrees of renal insufficiency [abstract p1598]
    • 10-13 April; Vienna, Austria
    • Merdjan H, Tarral A, Haazen W, et al. Pharmacokinetics and tolerability of NXL 104 in normal subjects and patients with varying degrees of renal insufficiency [abstract P1598]. Paper presented at 20th European Congress of Clinical Microbiology and Infectious Diseases; 10-13 April, 2010; Vienna, Austria
    • (2010) Paper Presented at 20th European Congress of Clinical Microbiology and Infectious Diseases;
    • Merdjan, H.1    Tarral, A.2    Haazen, W.3
  • 56
    • 84971559966 scopus 로고    scopus 로고
    • Evaluation of ceftazidime-Avibactam (caz-Avi) dose regimens for phase III study in patients with different renal function. [abstract a-635]
    • 9-12 September; San Francisco, California, USA
    • Li J, Zhou D, Nichols W, et al. Evaluation of ceftazidime-Avibactam (CAZ-AVI) dose regimens for phase III study in patients with different renal function. [abstract A-635]. Paper presented at 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy; 9-12 September, 2012; San Francisco, California, USA
    • (2012) Paper Presented at 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy;
    • Li, J.1    Zhou, D.2    Nichols, W.3
  • 57
    • 84939841905 scopus 로고    scopus 로고
    • Prescribing information for ceftazidime injection
    • FORTAZ; Research Triangle Park, NC
    • FORTAZ. Prescribing Information for Ceftazidime injection. GlaxoSmithKline, LLC; Research Triangle Park, NC: 2010
    • (2010) GlaxoSmithKline LLC
  • 58
    • 84940007604 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of single and multiple ascending doses of avibactam alone and in combination with ceftazidime in healthy male volunteers: Results of two randomized, placebocontrolled studies
    • Merdjan H, Rangaraju M, Tarral A. Safety and pharmacokinetics of single and multiple ascending doses of avibactam alone and in combination with ceftazidime in healthy male volunteers: results of two randomized, placebocontrolled studies. Clin Drug Invest 2015;35:307-17
    • (2015) Clin Drug Invest , vol.35 , pp. 307-317
    • Merdjan, H.1    Rangaraju, M.2    Tarral, A.3
  • 59
    • 78650664486 scopus 로고    scopus 로고
    • Evaluation of ceftazidime and nxl104 in two murine models of infection due to kpc-producing klebsiella pneumoniae
    • Endimiani A, Hujer KM, Hujer AM, et al. Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae. Antimicrob Agents Chemother 2011;55:82-5
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 82-85
    • Endimiani, A.1    Hujer, K.M.2    Hujer, A.M.3
  • 60
    • 84908638638 scopus 로고    scopus 로고
    • Efficacy of a ceftazidime-Avibactam combination in a murine model of septicemia caused by enterobacteriaceae species producing ampc or extendedspectrum b-lactamases
    • Levasseur P, Girard A-M, Lavallade L, et al. Efficacy of a ceftazidime-Avibactam combination in a murine model of septicemia caused by Enterobacteriaceae species producing AmpC or extendedspectrum b-lactamases. Antimicrob Agents Chemother 2014;58:6490-5
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 6490-6495
    • Levasseur, P.1    Girard, A.-M.2    Lavallade, L.3
  • 61
    • 84869237392 scopus 로고    scopus 로고
    • Comparative in vitro and in vivo efficacies of human simulated doses of ceftazidime and ceftazidime-Avibactam against pseudomonas aeruginosa
    • Crandon JL, Schuck VJ, Banevicius MA, et al. Comparative in vitro and in vivo efficacies of human simulated doses of ceftazidime and ceftazidime-Avibactam against Pseudomonas aeruginosa. Antimicrob Agents Chemother 2012;56:6137-46
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 6137-6146
    • Crandon, J.L.1    Schuck, V.J.2    Banevicius, M.A.3
  • 62
    • 84908271938 scopus 로고    scopus 로고
    • In vivo efficacy of humanized exposures of ceftazidimeavibactam in comparison with ceftazidime against contemporary enterobacteriaceae isolates
    • MacVane SH, Crandon JL, Nichols WW, et al. In vivo efficacy of humanized exposures of ceftazidimeavibactam in comparison with ceftazidime against contemporary Enterobacteriaceae isolates. Antimicrob Agents Chemother 2014;58:6913-19
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 6913-6919
    • MacVane, S.H.1    Crandon, J.L.2    Nichols, W.W.3
  • 63
    • 84896844160 scopus 로고    scopus 로고
    • Efficacies of ceftazidime-Avibactam and ceftazidime against pseudomonas aeruginosa in a murine lung infection model
    • Housman ST, Crandon JL, Nichols WW, et al. Efficacies of ceftazidime-Avibactam and ceftazidime against Pseudomonas aeruginosa in a murine lung infection model. Antimicrob Agents Chemother 2014;58:1365-71
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 1365-1371
    • Housman, S.T.1    Crandon, J.L.2    Nichols, W.W.3
  • 64
    • 84911896976 scopus 로고    scopus 로고
    • Microbiological interaction studies between ceftazidime-Avibactam and lung surfactant and between ceftazidimeavibactam and antibacterial agents of other classes
    • Dallow J, Otterson LG, Huband MD, et al. Microbiological interaction studies between ceftazidime-Avibactam and lung surfactant and between ceftazidimeavibactam and antibacterial agents of other classes. Int J Antimicrob Agents 2014;44:552-6
    • (2014) Int J Antimicrob Agents , vol.44 , pp. 552-556
    • Dallow, J.1    Otterson, L.G.2    Huband, M.D.3
  • 65
    • 84877123198 scopus 로고    scopus 로고
    • Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-Abdominal infections in hospitalized adults: Results of a randomized, double-blind, phase II trial
    • Lucasti C, Popescu I, Ramesh MK, et al. Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-Abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial. J Antimicrob Chemother 2013;68:1183-92
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1183-1192
    • Lucasti, C.1    Popescu, I.2    Ramesh, M.K.3
  • 66
    • 84870399321 scopus 로고    scopus 로고
    • Efficacy and safety of ceftazidime-Avibactam versus imipenemcilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: Results of a prospective, investigatorblinded, randomized study
    • Vazquez JA, González Patzán LD, Stricklin D, et al. Efficacy and safety of ceftazidime-Avibactam versus imipenemcilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigatorblinded, randomized study. Curr Med Res Opin 2012;28:1921-31
    • (2012) Curr Med Res Opin , vol.28 , pp. 1921-1931
    • Vazquez, J.A.1    González Patzán, L.D.2    Stricklin, D.3
  • 67
    • 84949099490 scopus 로고    scopus 로고
    • Efficacy and safety of ceftazidimeavibactam plus metronidazole versus meropenem in the treatment of complicated intra-Abdominal infection-results from a phase III program [abstract 0191]
    • 25-28 April; Copenhagen, Denmark
    • Mazuski JE, Gasnik L, Armstrong J, et al. Efficacy and safety of ceftazidimeavibactam plus metronidazole versus meropenem in the treatment of complicated intra-Abdominal infection-results from a Phase III program [abstract 0191]. Paper presented at 25th European Congress of Clinical Microbiology and Infectious Diseases; 25-28 April, 2015; Copenhagen, Denmark
    • (2015) Paper Presented at 25th European Congress of Clinical Microbiology and Infectious Diseases;
    • Mazuski, J.E.1    Gasnik, L.2    Armstrong, J.3
  • 68
    • 84939841907 scopus 로고    scopus 로고
    • Efficacy and safety of ceftazidimeavibactam and best available therapy in the treatment of ceftazidime-resistant infections-results from a phase III study [abstract lbev0061b]
    • 25-28 April; Copenhagen, Denmark
    • Carmeli Y, Armstrong J, Laud P, et al. Efficacy and safety of ceftazidimeavibactam and best available therapy in the treatment of ceftazidime-resistant infections-results from a Phase III study [abstract LBEV0061b]. Paper presented at 25th European Congress of Clinical Microbiology and Infectious Diseases; 25-28 April, 2015; Copenhagen, Denmark
    • (2015) Paper Presented at 25th European Congress of Clinical Microbiology and Infectious Diseases;
    • Carmeli, Y.1    Armstrong, J.2    Laud, P.3
  • 69
    • 0003358488 scopus 로고    scopus 로고
    • Performance standards for antimicrobial susceptibility testing;
    • Clinical and Laboratory Standards InstituteWayne; PA, USA
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; Twentieth informational supplement. M100-S20 Wayne; PA, USA: 2010
    • (2010) Twentieth Informational Supplement. , pp. M100-S20


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