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Lipka, J.2
Gyaw, S.3
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55
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84894413746
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Combined population pharmacokinetic analysis of four phase 1studies with NXL104
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abstract P1599
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Felices M, Gualano V, Tarral A, Sable C, Merdjan H. Combined population pharmacokinetic analysis of four phase 1studies with NXL104 [abstract P1599]. 20th European Congress of Clinical Microbiology and Infectious Diseases; April 10-13, 2010; Vienna, Austria.
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20th European Congress of Clinical Microbiology and Infectious Diseases; April 10-13, 2010; Vienna, Austria
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Felices, M.1
Gualano, V.2
Tarral, A.3
Sable, C.4
Merdjan, H.5
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56
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84894426346
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Population pharmacokinetic modeling of ceftazidime (CAZ) and avibactam (AVI) in healthy volunteers and patients with complicated intra-abdominal infection (cIAI)
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abstract A-634
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Li J, Knebel W, Riggs M, Zou D, Nichols W, Das S. Population pharmacokinetic modeling of ceftazidime (CAZ) and avibactam (AVI) in healthy volunteers and patients with complicated intra-abdominal infection (cIAI) [abstract A-634]. 52nd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 9-12, 2012; San Francisco, CA.
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52nd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 9-12, 2012; San Francisco, CA
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Li, J.1
Knebel, W.2
Riggs, M.3
Zou, D.4
Nichols, W.5
Das, S.6
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57
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84894448046
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Concentration of avibactam (AVI) and ceftazidime (CAZ) in plasma and epithelial lining fluid (ELF) in healthy volunteers
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abstract A-1027
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Nicolau DP, Siew L, Armstrong J, Edeki T, Bouw R. Concentration of avibactam (AVI) and ceftazidime (CAZ) in plasma and epithelial lining fluid (ELF) in healthy volunteers [abstract A-1027]. 53rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 10-13, 2013; Denver, CO.
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53rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 10-13, 2013; Denver, CO
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Nicolau, D.P.1
Siew, L.2
Armstrong, J.3
Edeki, T.4
Bouw, R.5
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58
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84894449333
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Effect of pulmonary surfactant on the in vitro antibacterial activity of ceftazidime-avibactam
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abstract E-1170
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Huband MD, Otterson LG, Andrews B, Nichols WW. Effect of pulmonary surfactant on the in vitro antibacterial activity of ceftazidime-avibactam [abstract E-1170]. 53rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 10-13, 2013; Denver, CO.
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53rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 10-13, 2013; Denver, CO
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Huband, M.D.1
Otterson, L.G.2
Andrews, B.3
Nichols, W.W.4
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59
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84894445050
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Pharmacokinetics and tolerability of NXL104 in normal subjects and patients with varying degrees of renal insufficiency
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abstract P1598
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Merdjan H, Tarral A, Haazen W, Evene E, Robertson M, Sable C. Pharmacokinetics and tolerability of NXL104 in normal subjects and patients with varying degrees of renal insufficiency [abstract P1598]. 20th European Congress of Clinical Microbiology and Infectious Diseases; April 10-13, 2010; Vienna, Austria.
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20th European Congress of Clinical Microbiology and Infectious Diseases; April 10-13, 2010; Vienna, Austria
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Merdjan, H.1
Tarral, A.2
Haazen, W.3
Evene, E.4
Robertson, M.5
Sable, C.6
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61
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84894421624
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The pharmacodynamics of avibactam (NXL104) in combination with either ceftaroline or ceftazidime against β-lactamase producing Enterobacteriaceae
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abstract A-631
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Noel AR, Tomaselli SG, Nicholls DL, Bowker KE, Williams G, MacGowan AP. The pharmacodynamics of avibactam (NXL104) in combination with either ceftaroline or ceftazidime against β-lactamase producing Enterobacteriaceae [abstract A-631]. 52nd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 9-12, 2012; San Francisco, CA.
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52nd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 9-12, 2012; San Francisco, CA
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Noel, A.R.1
Tomaselli, S.G.2
Nicholls, D.L.3
Bowker, K.E.4
Williams, G.5
MacGowan, A.P.6
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63
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84894469360
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Pharmacokinetics (PK) and efficacy of ceftazidime (CAZ)/NXL104 combination in a murine pneumonia model caused by an AmpC-producing Klebsiella pneumoniae
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abstract A1-006
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Merdjan H, Girard AM, Miossec C, Robertson M, Levasseur, P. Pharmacokinetics (PK) and efficacy of ceftazidime (CAZ)/NXL104 combination in a murine pneumonia model caused by an AmpC-producing Klebsiella pneumoniae [abstract A1-006]. 49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, CA.
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49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, CA
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Merdjan, H.1
Girard, A.M.2
Miossec, C.3
Robertson, M.4
Levasseur, P.5
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64
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84894475332
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Efficacy of ceftazidime/ NXL104 combination in murine septicemia caused by extended-spectrum β-lactamases and AmpC-producing Enterobacteriaceae sp.
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abstract P1564
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Levasseur P, Girard AM, Lavallade L, et al. Efficacy of ceftazidime/ NXL104 combination in murine septicemia caused by extended-spectrum β-lactamases and AmpC-producing Enterobacteriaceae sp. [abstract P1564]. 20th European Congress of Clinical Microbiology and Infectious Diseases; April 10-13, 2010; Vienna, Austria.
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20th European Congress of Clinical Microbiology and Infectious Diseases; April 10-13, 2010; Vienna, Austria
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Levasseur, P.1
Girard, A.M.2
Lavallade, L.3
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65
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78650664486
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Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae
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Endimiani A, Hujer KM, Hujer AM, Pulse ME, Weiss WJ, Bonomo RA. Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae. Antimicrob Agents Chemother. 2011;55:82-85.
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(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 82-85
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Endimiani, A.1
Hujer, K.M.2
Hujer, A.M.3
Pulse, M.E.4
Weiss, W.J.5
Bonomo, R.A.6
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66
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84894427057
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Pharmacokinetics of the new β-lactamase inhibitor NXL104 in an experimental rabbit meningitis model: Restoration of the bacteriological efficacy of ceftazidime (CAZ) against a class C producing K. pneumoniae
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abstract F1-321
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Cottagnoud P, Merdjan H, Acosta F, et al. Pharmacokinetics of the new β-lactamase inhibitor NXL104 in an experimental rabbit meningitis model: restoration of the bacteriological efficacy of ceftazidime (CAZ) against a class C producing K. pneumoniae [abstract F1-321]. 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL.
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47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL
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Cottagnoud, P.1
Merdjan, H.2
Acosta, F.3
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67
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84894414096
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The efficacy of ceftazidime combined with NXL104, a novel β-lactamase inhibitor, in a mouse model of kidney infections induced by β-lactamase producing Enterobacteriaceae
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abstract P794
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Borgonovi M, Miossec C, Lowther J. The efficacy of ceftazidime combined with NXL104, a novel β-lactamase inhibitor, in a mouse model of kidney infections induced by β-lactamase producing Enterobacteriaceae [abstract P794]. 17th European Congress of Clinical Microbiology and Infectious Diseases; March 31-April 3, 2007; Munich, Germany.
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17th European Congress of Clinical Microbiology and Infectious Diseases; March 31-April 3, 2007; Munich, Germany
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Borgonovi, M.1
Miossec, C.2
Lowther, J.3
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68
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84870399321
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Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: Results of a prospective, investigator-blinded, randomized study
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Vazquez JA, González Patzán LD, Stricklin D, et al. Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study. Curr Med Res Opin. 2012;28:1921-1931.
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(2012)
Curr Med Res Opin
, vol.28
, pp. 1921-1931
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Vazquez, J.A.1
González Patzán, L.D.2
Stricklin, D.3
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69
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84894495332
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Effect of a supratherapeutic dose of ceftazidime on the QTc interval in a thorough QTc study
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abstract P1417
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Edeki T, Das S, Armstrong J, Mathews D. Effect of a supratherapeutic dose of ceftazidime on the QTc interval in a thorough QTc study [abstract P1417]. 22nd European Congress of Clinical Microbiology and Infectious Diseases; March 31-April 3, 2012; London, UK.
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22nd European Congress of Clinical Microbiology and Infectious Diseases; March 31-April 3, 2012; London, UK
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Edeki, T.1
Das, S.2
Armstrong, J.3
Mathews, D.4
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